EP1545575A4 - POLYPEPTIDES OF P. ARIASI POLYPEPTIDES P. PERNICIOSUS AND METHODS OF USE - Google Patents

POLYPEPTIDES OF P. ARIASI POLYPEPTIDES P. PERNICIOSUS AND METHODS OF USE

Info

Publication number
EP1545575A4
EP1545575A4 EP03759395A EP03759395A EP1545575A4 EP 1545575 A4 EP1545575 A4 EP 1545575A4 EP 03759395 A EP03759395 A EP 03759395A EP 03759395 A EP03759395 A EP 03759395A EP 1545575 A4 EP1545575 A4 EP 1545575A4
Authority
EP
European Patent Office
Prior art keywords
polypeptides
ariasi
methods
perniciosus
perniciosus polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP03759395A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1545575A2 (en
Inventor
Jesus G Valenzuela
Jose M C Ribiero
Shaden Kamhawi
Yasmine Belkaid
Laurent Fischer
Jean-Christophe Audonnet
Francis Milward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merial Ltd
US Department of Health and Human Services
Original Assignee
Merial Ltd
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, US Department of Health and Human Services filed Critical Merial Ltd
Priority to EP09175598A priority Critical patent/EP2158917A1/en
Publication of EP1545575A2 publication Critical patent/EP1545575A2/en
Publication of EP1545575A4 publication Critical patent/EP1545575A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/008—Leishmania antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP03759395A 2002-09-19 2003-09-18 POLYPEPTIDES OF P. ARIASI POLYPEPTIDES P. PERNICIOSUS AND METHODS OF USE Ceased EP1545575A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09175598A EP2158917A1 (en) 2002-09-19 2003-09-18 P.ariasi polypeptides, P.perniciosus polypeptides and methods of use

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41232702P 2002-09-19 2002-09-19
US412327P 2002-09-19
US42585202P 2002-11-12 2002-11-12
US425852P 2002-11-12
PCT/US2003/029833 WO2004027041A2 (en) 2002-09-19 2003-09-18 P. ariasi polypeptides, p. perniciosus polypeptides and methods of use

Publications (2)

Publication Number Publication Date
EP1545575A2 EP1545575A2 (en) 2005-06-29
EP1545575A4 true EP1545575A4 (en) 2006-04-05

Family

ID=32033599

Family Applications (2)

Application Number Title Priority Date Filing Date
EP03759395A Ceased EP1545575A4 (en) 2002-09-19 2003-09-18 POLYPEPTIDES OF P. ARIASI POLYPEPTIDES P. PERNICIOSUS AND METHODS OF USE
EP09175598A Ceased EP2158917A1 (en) 2002-09-19 2003-09-18 P.ariasi polypeptides, P.perniciosus polypeptides and methods of use

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP09175598A Ceased EP2158917A1 (en) 2002-09-19 2003-09-18 P.ariasi polypeptides, P.perniciosus polypeptides and methods of use

Country Status (7)

Country Link
US (2) US7741437B2 (es)
EP (2) EP1545575A4 (es)
JP (2) JP2006516883A (es)
AU (1) AU2003275127A1 (es)
BR (1) BR0314629A (es)
MX (1) MXPA05003049A (es)
WO (1) WO2004027041A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05003049A (es) 2002-09-19 2005-11-17 Us Gov Health & Human Serv Polipeptidos de phlebotomus ariasi, polipeptidos de phlebotomus perniciosus y metodos de uso.
ES2447843T3 (es) 2002-10-29 2014-03-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polip�ptidos de Lutzomyia longipalpis y m�todos de uso
US9101557B2 (en) 2011-04-13 2015-08-11 Auburn University Combination of protein forms for hornfly vaccination

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102324A2 (en) * 2001-06-19 2002-12-27 The Gouvernment Of The United States Of America, As Represented By The Secretary Department Of Health And Human Services, Anti-arthropod vector vaccines methods of selecting and uses thereof

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US4036945A (en) 1976-05-03 1977-07-19 The Massachusetts General Hospital Composition and method for determining the size and location of myocardial infarcts
US4444487A (en) 1979-07-02 1984-04-24 Xerox Corporation Multiple-flash fuser
US4331647A (en) 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4745051A (en) 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
EP0173552B1 (en) 1984-08-24 1991-10-09 The Upjohn Company Recombinant dna compounds and the expression of polypeptides such as tpa
US4745055A (en) 1985-05-07 1988-05-17 California Biotechnology Inc. Fused protein for enzyme immunoassay system
EP0256654B1 (en) 1986-07-07 1996-09-18 Centocor, Inc. Chimeric murine/human immunoglobulin specific for tumour-associated 17-1A Antigen
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
DE3730599A1 (de) 1986-09-12 1988-07-07 Genentech Inc Verfahren zur kontinuierlichen herstellung von heterologen proteinen in eukaryontischen wirtszellen
IE872748L (en) 1986-10-16 1988-04-16 Arjomari Europ Polypeptides derived from the evvelope gene of human¹immunodeficiency virus in recombinant baculovirus infected¹insect cells
GB8626412D0 (en) 1986-11-05 1986-12-03 Clark M R Antibodies
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
AU622426B2 (en) 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
DE3743138A1 (de) 1987-12-18 1989-09-14 Mayr Christian Gmbh & Co Kg Schleifringlose, elektromagnetische ueberlastkupplung
DE68926504T2 (de) 1988-07-20 1996-09-12 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
CA2003300A1 (en) 1988-11-21 1990-05-21 Franklin Volvovitz Skin test and test kit for aids
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5397772A (en) * 1989-06-29 1995-03-14 The President And Fellows Of Harvard College Vasodilatory peptides from the salivary gland of the sand fly Lutzomyia longipalpis
US5270202A (en) 1989-11-03 1993-12-14 Syamal Raychaudhuri Anti-idiotypic antibodies to human melanoma-associated proteoglycan antigen
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
ATE149841T1 (de) 1990-01-26 1997-03-15 Immunomedics Inc Impfstoffe gegen krebs und infektionskrankheiten
EP0575491B1 (en) 1991-03-07 2003-08-13 Virogenetics Corporation Genetically engineered vaccine strain
US5709860A (en) 1991-07-25 1998-01-20 Idec Pharmaceuticals Corporation Induction of cytotoxic T-lymphocyte responses
WO1993001831A1 (en) 1991-07-25 1993-02-04 Idec Pharmaceuticals Corporation Induction of cytotoxic t-lymphocyte responses
US5643578A (en) 1992-03-23 1997-07-01 University Of Massachusetts Medical Center Immunization by inoculation of DNA transcription unit
US5662907A (en) 1992-08-07 1997-09-02 Cytel Corporation Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes
EP0671926B1 (en) 1992-08-11 2002-11-13 President And Fellows Of Harvard College Immunomodulatory peptides
US5593972A (en) 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
AU7529194A (en) 1993-09-03 1995-03-22 Mcgill University Differentially expressed (leishmania) genes and proteins
FR2712603B1 (fr) 1993-11-18 1996-02-09 Centre Nat Rech Scient Virus recombinants, préparation et utilisation en thérapie génique.
US5529780A (en) 1994-03-30 1996-06-25 Virogenetics Corporation Nucleotide and amino acid sequences of canine herpesvirus gB and gC
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
JP3881009B2 (ja) 1994-07-15 2007-02-14 バイオメリオ・ベー・ベー 核酸増幅方法を改良するためのｒｎａポリメラーゼの使用
WO1996034109A1 (en) 1995-04-25 1996-10-31 Vical Incorporated Single-vial formulations of dna/lipid complexes
AT402203B (de) 1995-06-13 1997-03-25 Himmler Gottfried Dipl Ing Dr Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren
EP0803573A1 (en) 1996-04-25 1997-10-29 Gesellschaft für Biotechnologische Forschung mbH (GBF) Polycistronic expression construct with cytokines for multivalent vaccines
FR2750865B1 (fr) 1996-06-27 1998-12-04 Rhone Merieux Vaccin vivant recombinant a base d'herpesvirus canin, notamment contre la maladie de carre, la rage ou le virus parainfluenza de type 2
US6090393A (en) 1996-07-03 2000-07-18 Merial Recombinant canine adenoviruses, method for making and uses thereof
AU737243B2 (en) 1996-07-03 2001-08-16 Merial, Inc. Recombinant canine adenovirus (CAV) containing exogenous DNA
US6156567A (en) 1996-07-03 2000-12-05 Merial Truncated transcriptionally active cytomegalovirus promoters
ATE292980T1 (de) 1996-10-11 2005-04-15 Univ California Immunostimulierende oligonucleotidekonjugate
CA2306457A1 (en) * 1997-10-18 1999-04-29 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
US6017537A (en) 1998-12-18 2000-01-25 Connaught Laboratories, Inc. Formyl methionyl peptide vaccine adjuvant
US6645740B1 (en) 1999-06-10 2003-11-11 Merial Limited Nucleic acids encodings equine GM-CSF
MXPA05003049A (es) 2002-09-19 2005-11-17 Us Gov Health & Human Serv Polipeptidos de phlebotomus ariasi, polipeptidos de phlebotomus perniciosus y metodos de uso.
ES2447843T3 (es) 2002-10-29 2014-03-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polip�ptidos de Lutzomyia longipalpis y m�todos de uso

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102324A2 (en) * 2001-06-19 2002-12-27 The Gouvernment Of The United States Of America, As Represented By The Secretary Department Of Health And Human Services, Anti-arthropod vector vaccines methods of selecting and uses thereof

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BELKAID Y ET AL: "Delayed-type hypersensitivity to Phlebotomus papatasi sand fly bite: An adaptive response induced by the fly?", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 97, no. 12, 6 June 2000 (2000-06-06), pages 6704 - 6709, XP002330286, ISSN: 0027-8424 *
DATABASE GENESEQ_AA [online] DERWENT; 10 September 2003 (2003-09-10), VALENZUELA ET AL.: "P. papatasi salivary polypeptide immunogenic peptide Seq ID No 799", retrieved from EMBL Database accession no. ABR91965 *
DATABASE GENESEQ_AA [online] DERWENT; 10 September 2003 (2003-09-10), VALENZUELA ET AL.: "P. papatasi salivary polypeptide immunogenic peptide Seq ID No 844", retrieved from EMBL Database accession no. ABR92010 *
KAMHAWI S ET AL: "Protection against cutaneous leishmaniasis resulting from bites of uninfected sand flies", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 290, no. 5495, 17 November 2000 (2000-11-17), pages 1351 - 1354, XP002329857, ISSN: 0036-8075 *
KILLICK-KENDRICK R ET AL: "Mark-release-recapture of sand flies fed on leishmanial dogs: The natural life-cycle of Leishmania infantum in Phlebotomus ariasi", PARASSITOLOGIA (ROME), vol. 44, no. 1-2, June 2002 (2002-06-01), pages 67 - 71, XP009057499, ISSN: 0048-2951 *
VALENZUELA J G ET AL: "Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, vol. 194, no. 3, 6 August 2001 (2001-08-06), pages 331 - 342, XP002329854, ISSN: 0022-1007 *
VOLF P ET AL: "Salivary proteins and glycoproteins in phlebotomine sandflies of various species, sex and age", MEDICAL AND VETERINARY ENTOMOLOGY, BLACKWELL SCIENTIFIC PUBL., OXFORD,, GB, vol. 14, no. 3, September 2000 (2000-09-01), pages 251 - 256, XP002329855, ISSN: 0269-283X *
VOLF P ET AL: "SPECIES-SPECIFIC ANTIGENS IN SALIVARY GLANDS OF PHLEBOTOMINE SANDFLIES", PARASITOLOGY, CAMBRIDGE UNIVERSITY PRESS, LONDON, GB, vol. 122, no. PART 1, January 2001 (2001-01-01), pages 37 - 41, XP001206710, ISSN: 0031-1820 *

Also Published As

Publication number Publication date
WO2004027041A2 (en) 2004-04-01
JP2009060912A (ja) 2009-03-26
US20060004186A1 (en) 2006-01-05
WO2004027041A3 (en) 2005-02-24
BR0314629A (pt) 2005-08-02
US7741437B2 (en) 2010-06-22
EP2158917A1 (en) 2010-03-03
MXPA05003049A (es) 2005-11-17
AU2003275127A8 (en) 2004-04-08
US20100196381A1 (en) 2010-08-05
JP2006516883A (ja) 2006-07-13
EP1545575A2 (en) 2005-06-29
AU2003275127A1 (en) 2004-04-08

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