AU2003265853A8 - Hedgehog antagonists, methods and uses related thereto - Google Patents

Hedgehog antagonists, methods and uses related thereto

Info

Publication number
AU2003265853A8
AU2003265853A8 AU2003265853A AU2003265853A AU2003265853A8 AU 2003265853 A8 AU2003265853 A8 AU 2003265853A8 AU 2003265853 A AU2003265853 A AU 2003265853A AU 2003265853 A AU2003265853 A AU 2003265853A AU 2003265853 A8 AU2003265853 A8 AU 2003265853A8
Authority
AU
Australia
Prior art keywords
methods
hedgehog antagonists
uses related
uses
hedgehog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU2003265853A
Other versions
AU2003265853A1 (en
Inventor
Irina Karavanov
Lee Rubin
Henryk K Dudek
Karen Kotkow
Carmen Pepicelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Curis Inc
Original Assignee
Curis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US40714502P priority Critical
Priority to US60/407,145 priority
Application filed by Curis Inc filed Critical Curis Inc
Priority to PCT/US2003/027279 priority patent/WO2004020599A2/en
Publication of AU2003265853A1 publication Critical patent/AU2003265853A1/en
Publication of AU2003265853A8 publication Critical patent/AU2003265853A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
AU2003265853A 2002-08-29 2003-08-29 Hedgehog antagonists, methods and uses related thereto Abandoned AU2003265853A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US40714502P true 2002-08-29 2002-08-29
US60/407,145 2002-08-29
PCT/US2003/027279 WO2004020599A2 (en) 2002-08-29 2003-08-29 Hedgehog antagonists, methods and uses related thereto

Publications (2)

Publication Number Publication Date
AU2003265853A1 AU2003265853A1 (en) 2004-03-19
AU2003265853A8 true AU2003265853A8 (en) 2004-03-19

Family

ID=31978427

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003265853A Abandoned AU2003265853A1 (en) 2002-08-29 2003-08-29 Hedgehog antagonists, methods and uses related thereto

Country Status (2)

Country Link
AU (1) AU2003265853A1 (en)
WO (1) WO2004020599A2 (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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US7709454B2 (en) * 1997-06-20 2010-05-04 New York University Methods and compositions for inhibiting tumorigenesis
US7741298B2 (en) * 1997-06-20 2010-06-22 New York University Method and compositions for inhibiting tumorigenesis
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US7671200B2 (en) 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
JP5184077B2 (en) * 2004-03-26 2013-04-17 キュリス,インコーポレイテッド RNA interference modulator of hedgehog signaling and use thereof
EP1862180A4 (en) * 2005-03-25 2010-09-15 Takeda Pharmaceutical Prophylactic/therapeutic agent for cancer
EP1966130B1 (en) 2005-12-23 2013-12-11 Zealand Pharma A/S Modified lysine-mimetic compounds
AR064626A1 (en) 2006-12-21 2009-04-15 Wyeth Corp Synthesis of pyrrolidine compounds
TWI433674B (en) 2006-12-28 2014-04-11 Infinity Discovery Inc Cyclopamine analogs
US8716479B2 (en) 2007-12-27 2014-05-06 Infinity Pharmaceuticals, Inc. Methods for stereoselective reduction
MX2010009372A (en) 2008-02-26 2010-09-22 Takeda Pharmaceutical Fused heterocyclic derivative and use thereof.
US20110217294A1 (en) * 2008-04-11 2011-09-08 Daniel Fults Combination of hgf inhibitor and hedgehog inhibitor to treat cancer
US7981892B2 (en) 2008-04-29 2011-07-19 Eli Lilly And Company Disubstituted phthalazine hedgehog pathway antagonists
US8404687B2 (en) 2008-11-03 2013-03-26 Eli Lilly And Company Disubstituted phthalazine hedgehog pathway antagonists
WO2010056620A1 (en) 2008-11-17 2010-05-20 Eli Lilly And Company Tetrasubstituted pyridazines hedgehog pathway antagonists
JP5518887B2 (en) 2008-11-17 2014-06-11 イーライ リリー アンド カンパニー Tetrasubstituted pyridazine hedgehog pathway antagonist
AR077014A1 (en) 2009-06-19 2011-07-27 Lilly Co Eli Phthalazine derivative compound 1,4-disubstituted pharmaceutical composition comprising the same and use for preparing a medicament useful for treating cancer
ES2567134T3 (en) 2009-08-05 2016-04-20 Infinity Pharmaceuticals, Inc. enzymatic transamination of cyclopamine analogs
US8614208B2 (en) 2009-08-26 2013-12-24 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
EP2471789B9 (en) 2009-08-26 2015-03-25 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
SG178504A1 (en) 2009-08-26 2012-04-27 Takeda Pharmaceutical Fused heterocyclic ring derivative and use thereof
EP2471791B1 (en) 2009-08-26 2014-11-12 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
CA2799579A1 (en) 2010-05-21 2011-11-24 Intellikine, Inc. Chemical compounds, compositions and methods for kinase modulation
WO2012037217A1 (en) 2010-09-14 2012-03-22 Infinity Pharmaceuticals, Inc. Transfer hydrogenation of cyclopamine analogs
AU2011326427B2 (en) 2010-11-10 2016-01-07 Infinity Pharmaceuticals Inc. Heterocyclic compounds and uses thereof
JP2014501790A (en) 2011-01-10 2014-01-23 インフィニティー ファーマシューティカルズ, インコーポレイテッド Process for the preparation of isoquinolinone and solid form of isoquinolinone
MX2014000648A (en) 2011-07-19 2014-09-25 Infinity Pharmaceuticals Inc Heterocyclic compounds and uses thereof.
WO2013012915A1 (en) 2011-07-19 2013-01-24 Infinity Pharmaceuticals Inc. Heterocyclic compounds and uses thereof
AU2012302197B2 (en) 2011-08-29 2016-01-07 Infinity Pharmaceuticals Inc. Heterocyclic compounds and uses thereof
WO2013049332A1 (en) 2011-09-29 2013-04-04 Infinity Pharmaceuticals, Inc. Inhibitors of monoacylglycerol lipase and methods of their use
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
AU2013337717B2 (en) 2012-11-01 2018-10-25 Infinity Pharmaceuticals, Inc. Treatment of cancers using PI3 kinase isoform modulators
BR112015029969A2 (en) 2013-05-30 2017-07-25 Infinity Pharmaceuticals Inc cancer treatment using pi3 isoform kinase modulators
WO2014085523A1 (en) 2012-11-29 2014-06-05 Strasspharma Llc Methods of modulating follicle stimulating hormone activity
EP2968347A4 (en) 2013-03-15 2016-11-02 Univ California Modulators of the eif2alpha pathway
WO2014151386A1 (en) 2013-03-15 2014-09-25 Infinity Pharmaceuticals, Inc. Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
US9192609B2 (en) 2013-04-17 2015-11-24 Hedgepath Pharmaceuticals, Inc. Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors
US9751888B2 (en) 2013-10-04 2017-09-05 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CA2925944A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
WO2015061204A1 (en) 2013-10-21 2015-04-30 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CN104906113A (en) * 2014-03-12 2015-09-16 淄博赛维医药技术有限公司 Antitumor medicine
SG11201607705XA (en) 2014-03-19 2016-10-28 Infinity Pharmaceuticals Inc Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
US20150320754A1 (en) 2014-04-16 2015-11-12 Infinity Pharmaceuticals, Inc. Combination therapies
WO2015168079A1 (en) 2014-04-29 2015-11-05 Infinity Pharmaceuticals, Inc. Pyrimidine or pyridine derivatives useful as pi3k inhibitors
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
AU2016271468B2 (en) 2015-06-04 2020-01-02 PellePharm, Inc. Topical formulations for delivery of hedgehog inhibitor compounds and use thereof
WO2017139497A1 (en) 2016-02-11 2017-08-17 PellePharm, Inc. Hedgehog inhibitor for use in relief of and treatment of pruritus or itching
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US20190216816A1 (en) 2016-06-24 2019-07-18 Infinity Pharmaceuticals, Inc. Combination therapies

Also Published As

Publication number Publication date
WO2004020599A3 (en) 2006-12-28
AU2003265853A1 (en) 2004-03-19
WO2004020599A2 (en) 2004-03-11

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase