EP1490382A4 - Verfahren zur herstellung von azithromycin und dabei verwendetes kristallines 9-desoxo-9a-aza-9a-homoerythromycin-a-hydrat - Google Patents
Verfahren zur herstellung von azithromycin und dabei verwendetes kristallines 9-desoxo-9a-aza-9a-homoerythromycin-a-hydratInfo
- Publication number
- EP1490382A4 EP1490382A4 EP02717187A EP02717187A EP1490382A4 EP 1490382 A4 EP1490382 A4 EP 1490382A4 EP 02717187 A EP02717187 A EP 02717187A EP 02717187 A EP02717187 A EP 02717187A EP 1490382 A4 EP1490382 A4 EP 1490382A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- homoerythromycin
- deoxo
- aza
- crystalline
- hydrate used
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/KR2002/000588 WO2003082889A1 (en) | 2001-03-21 | 2002-04-03 | Process of preparing azithromycin and crystalline 9-deoxo-9a-aza-9a-homoerythromycin a hydrate used therein |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1490382A1 EP1490382A1 (de) | 2004-12-29 |
EP1490382A4 true EP1490382A4 (de) | 2007-09-12 |
Family
ID=33411531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02717187A Withdrawn EP1490382A4 (de) | 2002-04-03 | 2002-04-03 | Verfahren zur herstellung von azithromycin und dabei verwendetes kristallines 9-desoxo-9a-aza-9a-homoerythromycin-a-hydrat |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1490382A4 (de) |
JP (1) | JP2005522470A (de) |
CN (1) | CN1276919C (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101624412B (zh) * | 2008-07-10 | 2012-07-04 | 刘力 | 大环内酯类衍生物及其制备和用途 |
CN101724000B (zh) * | 2008-10-29 | 2012-05-30 | 广东东阳光药业有限公司 | 一种红霉素的结晶方法 |
CN103159811A (zh) * | 2011-12-10 | 2013-06-19 | 山东方明药业集团股份有限公司 | 一种阿齐霉素中间体9a-脱氧-9a-氮杂-9a-高红霉素A的制备方法 |
CN102417531B (zh) * | 2011-12-20 | 2014-06-11 | 浙江国邦药业有限公司 | 一种阿奇霉素一水合物的制备方法 |
CN105315316A (zh) * | 2014-07-21 | 2016-02-10 | 常州制药厂有限公司 | 一种阿奇霉素中间体的制备方法 |
CN106632543A (zh) * | 2016-12-20 | 2017-05-10 | 宁夏启元药业有限公司 | 一种氮红霉素的合成方法 |
CN109293719A (zh) * | 2018-10-12 | 2019-02-01 | 浙江国邦药业有限公司 | 一种二氢高红霉素新晶型化合物及其制备方法 |
CN114516895A (zh) * | 2020-11-19 | 2022-05-20 | 江苏威奇达药业有限公司 | 一种阿奇霉素胺结晶方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0827965A2 (de) * | 1996-07-11 | 1998-03-11 | Astur-Pharma, S.A. | Synthese von 9-Deoxo-9a-Aza 11,12-Deoxy-9a-Methyl-9a-Homoerythromycin A 11,12-hydrogenorthoborat-dihydrat |
EP0941999A2 (de) * | 1998-03-13 | 1999-09-15 | Hovione Inter Ltd. | Herstellung von Azithromycindihydrat |
WO2001000640A1 (en) * | 1999-06-29 | 2001-01-04 | Biochemie S.A. | Macrolides |
WO2002015842A2 (en) * | 2000-08-23 | 2002-02-28 | Wockhardt Limited | Process for preparation of anhydrous azithromycin |
-
2002
- 2002-04-03 JP JP2003580353A patent/JP2005522470A/ja active Pending
- 2002-04-03 CN CN02828700.2A patent/CN1276919C/zh not_active Expired - Fee Related
- 2002-04-03 EP EP02717187A patent/EP1490382A4/de not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0827965A2 (de) * | 1996-07-11 | 1998-03-11 | Astur-Pharma, S.A. | Synthese von 9-Deoxo-9a-Aza 11,12-Deoxy-9a-Methyl-9a-Homoerythromycin A 11,12-hydrogenorthoborat-dihydrat |
EP0941999A2 (de) * | 1998-03-13 | 1999-09-15 | Hovione Inter Ltd. | Herstellung von Azithromycindihydrat |
WO2001000640A1 (en) * | 1999-06-29 | 2001-01-04 | Biochemie S.A. | Macrolides |
WO2002015842A2 (en) * | 2000-08-23 | 2002-02-28 | Wockhardt Limited | Process for preparation of anhydrous azithromycin |
Non-Patent Citations (1)
Title |
---|
See also references of WO03082889A1 * |
Also Published As
Publication number | Publication date |
---|---|
CN1625560A (zh) | 2005-06-08 |
EP1490382A1 (de) | 2004-12-29 |
CN1276919C (zh) | 2006-09-27 |
JP2005522470A (ja) | 2005-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20040903 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: SEONG, MI RA Inventor name: KIM, GI JEONG Inventor name: SUH, KWEE HYUN Inventor name: YUN, SANG MIN |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: KIM, GI JEONG Inventor name: YUN, SANG MIN Inventor name: SUH, KWEE HYUN Inventor name: SEONG, MI RA |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20070813 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/7048 20060101ALI20070807BHEP Ipc: A61P 31/04 20060101ALI20070807BHEP Ipc: C07H 17/08 20060101AFI20031015BHEP |
|
17Q | First examination report despatched |
Effective date: 20071016 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20091102 |