EP1299036A2 - Dispositif chirurgical d'extraction de cellules de tissu d'une structure biologique - Google Patents
Dispositif chirurgical d'extraction de cellules de tissu d'une structure biologiqueInfo
- Publication number
- EP1299036A2 EP1299036A2 EP01957706A EP01957706A EP1299036A2 EP 1299036 A2 EP1299036 A2 EP 1299036A2 EP 01957706 A EP01957706 A EP 01957706A EP 01957706 A EP01957706 A EP 01957706A EP 1299036 A2 EP1299036 A2 EP 1299036A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- liquid jet
- surgical device
- tissue cells
- section
- capillary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3203—Fluid jet cutting instruments
- A61B17/32037—Fluid jet cutting instruments for removing obstructions from inner organs or blood vessels, e.g. for atherectomy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/08—Lipoids
Definitions
- the invention relates to a surgical device for removing tissue cells from a biological structure according to the preamble of claim 1. Such instruments are used in surgical clinics.
- the cell is the basic unit of living matter and essentially consists of one or more cell nuclei that are embedded in the cytoplasm and one
- Structure such as the human body.
- Fat tissue can be taken from all possible parts of the body.
- Adipose tissue to be inserted With the help of those exiting in all directions
- Tissue cells such as blood cells. This damages the human body and therefore complicates and extends the healing process.
- ultrasonic probes emit radiation on all sides and therefore cannot be used in a targeted manner. For example, it is not possible to work on border areas between the fat tissue to be extracted and an adjacent healthy tissue without damaging the healthy tissue.
- the invention is therefore based on the object of developing a surgical device for removing tissue cells from a biological structure, with which tissue cells can be separated and removed undamaged.
- the invention eliminates the disadvantages of the prior art mentioned.
- the particular advantage of the invention is that neither the tissue cells to be removed nor the adjacent and remaining tissue cells are damaged during the removal. On the one hand, this makes it possible to continue using the removed tissue cells, for example for an increase in the tissue cells carried out outside the human or animal body. This type of withdrawal but also protects all healthy tissue cells that remain in the body, because only the desired tissue cells are removed. For this purpose, it is expedient to design the liquid jet like a peeling knife or a scraper.
- the more or less flat liquid jet extends transversely at a right angle to the suction lines located on an axial line, because this results in the shortest transport path of the removed tissue cells between the peeling edge of the liquid jet and the suction holes.
- Fig. 1 the surgical handpiece of the surgical device with a round liquid jet
- Fig. 2 the surgical handpiece with a flat liquid jet.
- the structure of the surgical device for removing vital tissue cells from a biological structure largely corresponds to that of a liquid jet device for separating a biological structure.
- a separation device is generally mine known and need not be shown separately here.
- a corresponding separation device is described in EP 0 551 920 B1.
- the surgical device for removing tissue cells from a biological structure thus essentially consists of a pressure generator, a piston-cylinder unit and a special surgical handpiece 1.
- a cartridge is inserted in a form-fitting manner, which is fitted with a sterile Liquid is filled and which is connected to the surgical handpiece 1.
- the pressure medium of the pressure generator loads the cartridge, as a result of which the sterile liquid is pressed out of the cartridge and conveyed to the surgical handpiece 1, where it emerges under pressure in the form of a fine liquid jet.
- All device units of this high-pressure liquid jet device are designed and coordinated so that on the one hand a continuous sterile chain is guaranteed for the liquid and on the other hand the escaping liquid jet can intelligently process different biological structures with the highest precision.
- the special surgical handpiece 1 consists of a handle gap (not shown) for the surgeon and a cannula 2 for insertion into the biological structure. Inside the cannula 2 is a capillary 3 for the emerging
- Liquid jet and a capillary 4 for the suction of separated tissue cells and the used liquid Liquid jet and a capillary 4 for the suction of separated tissue cells and the used liquid.
- the capillary 3 for supplying liquid is preferably arranged on the inside and coaxial with the cannula 2, and the capillary 4 for suctioning the tissue cells is designed as an annular channel encompassing the inside capillary 2.
- both capillaries 3 and 4 can of course also be arranged separately next to one another in the cannula 2.
- the capillary 4 for suctioning the tissue cells has at the distal end of the cannula 2 a plurality of radial suction openings 5, which are arranged on two opposite axial lines at equal distances from one another.
- Suction openings 5 are selected so that, on the one hand, the build-up of a suction force and, on the other hand, the passability of the separated tissue cells is made possible.
- the capillary 3 for the emerging liquid jet likewise opens at the distal end of the cannula 2 in a nozzle piece 6 which is rigidly connected to the cannula 2.
- the nozzle piece 6 is preferably screwed into the cannula 2.
- the nozzle piece 6 has an axially arranged nozzle opening 7, which is designed in a special way for a wide variety of applications.
- the nozzle opening 7 of the nozzle gap 6 according to FIG. 2 is designed to be flat in such a way that an emerging liquid jet with a strongly flattened cross section results.
- This flat liquid jet is oriented such that each of the two rows of radial suction openings 5 is at right angles to one of the two flattened long sides of the liquid cross section.
- the nozzle opening 7 of the nozzle piece 6 is designed, for example, for the removal of vital tissue cells from the liver according to FIG. 1 round or approximately round in such a way that a liquid jet with a round cross section, with a round cross section with a slight flattening or with an oval cross-section emerges.
- the radial suction openings 5 are arranged approximately at right angles to the existing flattenings of the liquid jet.
- the dashed outlet line 8 is intended to indicate that the emerging liquid jet can also emerge at a predetermined angle with respect to the central axis of the cannula 2 by a corresponding shape and arrangement of the nozzle opening 7 in the nozzle piece 6.
- a minimal surgical incision is first made in the patient's abdominal wall and then the cannula 2 with the liquid jet already emerging under pressure is attached to this opening.
- the opening of the abdominal wall is pressed apart so far by the pressure of the emerging liquid jet that the cannula 2 of the
- Surgical handpiece can be easily inserted under the abdominal wall into the area of the fatty tissue.
- the surgeon can feel the position of the cannula 2 and the direction and position of the flat liquid jet at the pressure emanating from the liquid jet outside the abdominal wall and correct or change it with the guide hand.
- the pressure of the liquid jet is regulated on site in such a way that the flat liquid jet emerges with a force which does not destroy the adipose tissue cells but only displaces it from the jet area.
- neighboring fat cells shift and stand out from one another, so that free spaces are formed between the fat cells, into which the liquid jet penetrates and there pushes apart the seams of the neighboring cell membranes that are still present.
- the cannula 2 of the surgical handpiece 1 is only equipped with such a nozzle piece 6, which produces a round, or approximately round and punctiform liquid jet, and a lower pressure on the liquid jet is set on the surgical device.
- the procedure is the same as for the removal of fat cells.
- the punctiform liquid jet is moved sideways on a line to increase the peeling effect.
- the individual or smaller cell bundles are again suctioned off and then placed in a corresponding station for the purpose of cell multiplication.
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Surgical Instruments (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10033278A DE10033278B4 (de) | 2000-07-07 | 2000-07-07 | Chirurgische Einrichtung zur Entnahme von Gewebezellen aus einer biologischen Struktur |
DE10033278 | 2000-07-07 | ||
PCT/DE2001/002417 WO2002003866A2 (fr) | 2000-07-07 | 2001-07-05 | Dispositif chirurgical d'extraction de cellules de tissu d'une structure biologique |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1299036A2 true EP1299036A2 (fr) | 2003-04-09 |
Family
ID=7648271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01957706A Withdrawn EP1299036A2 (fr) | 2000-07-07 | 2001-07-05 | Dispositif chirurgical d'extraction de cellules de tissu d'une structure biologique |
Country Status (5)
Country | Link |
---|---|
US (1) | US20040092987A1 (fr) |
EP (1) | EP1299036A2 (fr) |
CA (1) | CA2415129C (fr) |
DE (1) | DE10033278B4 (fr) |
WO (1) | WO2002003866A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE20210646U1 (de) * | 2002-07-09 | 2002-10-02 | Pein Andreas | Chirurgische Einrichtung zur Entnahme von Gewebezellen aus einer biologischen Struktur |
DE20211555U1 (de) | 2002-07-12 | 2002-11-28 | Peln Andreas | Chirurgische Einrichtung zur Entnahme von Gewebezellen aus einer biologischen Struktur |
DE102005030931B4 (de) * | 2005-06-30 | 2009-03-05 | P + P Medical Gmbh | Operationshandstück einer chirurgischen Einrichtung zur Entnahme von Gewebe aus einer biologischen Strukur |
DE202005018601U1 (de) * | 2005-11-29 | 2006-04-13 | Human Med Ag | Chirurgische Einrichtung zum Trennen einer biologischen Struktur mit Hilfe eines Flüssigkeitsstrahls |
DE102007002486B4 (de) * | 2007-01-11 | 2012-04-05 | Human Med Ag | Applikator für das chirurgische Wasserstrahltrennen zur Erzeugung eines Flachstrahls und Verfahren zur Herstellung des Applikators |
US9867636B2 (en) * | 2013-03-15 | 2018-01-16 | The Regents Of The University Of California | Method, apparatus, and a system for a water jet |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE206610C (fr) * | ||||
RO57165A2 (fr) * | 1972-09-29 | 1974-12-15 | ||
DE2447513A1 (de) * | 1974-10-04 | 1976-04-08 | Henke Sass Wolf Gmbh | Absaugkuerette fuer saugapparate |
US4024866A (en) * | 1974-12-02 | 1977-05-24 | Hydro Pulse Corporation | Surgical apparatus for removal of tissue |
DE3715418A1 (de) * | 1986-05-08 | 1987-11-12 | Olympus Optical Co | Lithotom |
DE4018736A1 (de) * | 1990-06-12 | 1992-01-02 | Wigbert S Prof Dr Med Rau | Hochdruck-aspirationskatheter zur wiedereroeffnung von krankhaft verschlossenen gefaessen |
DE4200976C2 (de) * | 1992-01-16 | 1995-08-24 | Andreas Pein | Vorrichtung zum Trennen einer biologischen Struktur, insbesondere des menschlichen Gewebes |
US5322504A (en) * | 1992-05-07 | 1994-06-21 | United States Surgical Corporation | Method and apparatus for tissue excision and removal by fluid jet |
MX9307838A (es) * | 1992-12-11 | 1994-06-30 | American Hydro Surgical Instr | Accesorio de desconexion rapida para acoplar una punta de sonda de prueba intercambiable con un instrumento laparoscopico. |
US5788667A (en) * | 1996-07-19 | 1998-08-04 | Stoller; Glenn | Fluid jet vitrectomy device and method for use |
US5766194A (en) * | 1996-12-23 | 1998-06-16 | Georgia Skin And Cancer Clinic, Pc | Surgical apparatus for tissue removal |
DE20009786U1 (de) * | 2000-05-31 | 2000-10-19 | Taufig Ahmmed Ziah | Fettabsaugvorrichtung |
-
2000
- 2000-07-07 DE DE10033278A patent/DE10033278B4/de not_active Expired - Fee Related
-
2001
- 2001-07-05 US US10/332,524 patent/US20040092987A1/en not_active Abandoned
- 2001-07-05 CA CA002415129A patent/CA2415129C/fr not_active Expired - Fee Related
- 2001-07-05 WO PCT/DE2001/002417 patent/WO2002003866A2/fr active Application Filing
- 2001-07-05 EP EP01957706A patent/EP1299036A2/fr not_active Withdrawn
Non-Patent Citations (1)
Title |
---|
See references of WO0203866A3 * |
Also Published As
Publication number | Publication date |
---|---|
CA2415129A1 (fr) | 2002-01-17 |
CA2415129C (fr) | 2007-09-04 |
WO2002003866A3 (fr) | 2002-03-28 |
WO2002003866A2 (fr) | 2002-01-17 |
DE10033278A1 (de) | 2002-01-24 |
US20040092987A1 (en) | 2004-05-13 |
DE10033278B4 (de) | 2006-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030204 |
|
AK | Designated contracting states |
Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
17Q | First examination report despatched |
Effective date: 20041208 |
|
19A | Proceedings stayed before grant |
Effective date: 20050107 |
|
19F | Resumption of proceedings before grant (after stay of proceedings) |
Effective date: 20070903 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: TAUFIG, AHMMED ZIAH |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20090203 |