EP1292189A2 - Composition orale de bacteries gram (+) et de glutamine pour la prevention et/ou le traitement de gastro-intestinaux - Google Patents

Composition orale de bacteries gram (+) et de glutamine pour la prevention et/ou le traitement de gastro-intestinaux

Info

Publication number
EP1292189A2
EP1292189A2 EP01937205A EP01937205A EP1292189A2 EP 1292189 A2 EP1292189 A2 EP 1292189A2 EP 01937205 A EP01937205 A EP 01937205A EP 01937205 A EP01937205 A EP 01937205A EP 1292189 A2 EP1292189 A2 EP 1292189A2
Authority
EP
European Patent Office
Prior art keywords
bacteria
gram
glutamine composition
composition
glutamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01937205A
Other languages
German (de)
English (en)
Other versions
EP1292189A4 (fr
Inventor
Pinaki Panigrahi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Maryland at Baltimore
Original Assignee
University of Maryland at Baltimore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Maryland at Baltimore filed Critical University of Maryland at Baltimore
Publication of EP1292189A2 publication Critical patent/EP1292189A2/fr
Publication of EP1292189A4 publication Critical patent/EP1292189A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne une composition et une méthode de traitement et de prévention de troubles gastro-intestinaux. La composition comprend une combinaison de bactéries Gram (+), en particulier Lactobacillus et/ou Bifidobacteria, et de glutamine. La méthode consiste à administrer oralement ou par voie naso-gastrique une composition contenant des bactéries Gram (+), en particulier Lactobacillus, et de glutamine. La composition, qui bloque la translocation d'agents bactériens tels que des bactéries Gram(-), assurant une protection contre d'autres agents infectieux, des toxines, des produits chimiques et des substances dangereuses, peut être utilisée dans la prévention et le traitement de symptômes et/ou de maladies qui résultent de la translocation de bactéries Gram(-), comprenant l'inflammation du tractus gastro-intestinal, l'entérocolite nécrosante néonatale et la sepsie bactérienne.
EP01937205A 2000-05-03 2001-05-03 Composition orale de bacteries gram (+) et de glutamine pour la prevention et/ou le traitement de gastro-intestinaux Withdrawn EP1292189A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20140800P 2000-05-03 2000-05-03
US201408P 2000-05-03
PCT/US2001/014080 WO2001083700A2 (fr) 2000-05-03 2001-05-03 Composition orale de bacteries gram (+) et de glutamine pour la prevention et/ou le traitement de dysfonctionnements gastro-intestinaux y compris l'inflammation du tractus gastro-intestinal, l'enterocolite necrosante neonatale et la sepsie bacterienne

Publications (2)

Publication Number Publication Date
EP1292189A2 true EP1292189A2 (fr) 2003-03-19
EP1292189A4 EP1292189A4 (fr) 2003-08-13

Family

ID=22745700

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01937205A Withdrawn EP1292189A4 (fr) 2000-05-03 2001-05-03 Composition orale de bacteries gram (+) et de glutamine pour la prevention et/ou le traitement de gastro-intestinaux

Country Status (4)

Country Link
EP (1) EP1292189A4 (fr)
AU (1) AU2001262966A1 (fr)
CA (1) CA2407724A1 (fr)
WO (1) WO2001083700A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0114419D0 (en) * 2001-06-13 2001-08-08 Mars Uk Ltd Health food
SE526711C2 (sv) 2003-01-31 2005-10-25 Probi Ab Nya stammar av Bifidobacterium med förmåga att överleva i magtarmkanalen och producera glutamin in vivo, samt kompositioner och användningar därav

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007808A (en) * 1995-06-23 1999-12-28 Dibra S.P.A. Pharmaceutical and diet formulations for the prophylaxis and treatment of gastrointestinal disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5533973A (en) * 1995-01-13 1996-07-09 Abbott Laboratories Alteration of nutritional product during enteral tube feeding
US5707353A (en) * 1995-12-21 1998-01-13 Abbott Laboratories Oral administration of beneficial agents
US5981590A (en) * 1997-03-17 1999-11-09 Probiotix, Inc. Oral glutamine in the prevention of neonatal necrotizing enterocolitis and other gastrointestinal mucosal damage
US6132710A (en) * 1997-03-17 2000-10-17 Probiotix, Inc. Preventing/treating neonatal NEC by administering lactobacillus salivarius and lactobacillus plantarum or a combination thereof
US6203797B1 (en) * 1998-01-06 2001-03-20 Stephen C. Perry Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome
US6262019B1 (en) * 1998-04-30 2001-07-17 Vit-Immune, L. C. Method of treatment of glutathione deficient mammals
US6156355A (en) * 1998-11-02 2000-12-05 Star-Kist Foods, Inc. Breed-specific canine food formulations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007808A (en) * 1995-06-23 1999-12-28 Dibra S.P.A. Pharmaceutical and diet formulations for the prophylaxis and treatment of gastrointestinal disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ROTH E ET AL: "GLUTAMIN: WIRKUNGEN AUF DAS IMMUNOSYSTEM, AUF EIWEISSHAUSHALT UND DARMFUNKTIONEN" WIENER KLINISCHE WOCHENSCHRIFT, NEW YORK, NY, US, vol. 108, no. 21, 1996, pages 669-676, XP000937773 ISSN: 0043-5325 *
See also references of WO0183700A2 *

Also Published As

Publication number Publication date
WO2001083700A3 (fr) 2002-02-07
AU2001262966A1 (en) 2001-11-12
EP1292189A4 (fr) 2003-08-13
CA2407724A1 (fr) 2001-11-08
WO2001083700A2 (fr) 2001-11-08

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