EP1259497A4 - Nouveaux ligands de la quinoline et complexes metalliques utilises pour le diagnostic et la therapie - Google Patents
Nouveaux ligands de la quinoline et complexes metalliques utilises pour le diagnostic et la therapieInfo
- Publication number
- EP1259497A4 EP1259497A4 EP01916286A EP01916286A EP1259497A4 EP 1259497 A4 EP1259497 A4 EP 1259497A4 EP 01916286 A EP01916286 A EP 01916286A EP 01916286 A EP01916286 A EP 01916286A EP 1259497 A4 EP1259497 A4 EP 1259497A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- diagnosis
- therapy
- metal complexes
- novel quinoline
- quinoline ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/517,252 US6277841B1 (en) | 2000-03-02 | 2000-03-02 | Quinoline ligands and metal complexes for diagnosis and therapy |
US517252 | 2000-03-02 | ||
PCT/US2001/006394 WO2001064660A1 (fr) | 2000-03-02 | 2001-02-28 | Nouveaux ligands de la quinoline et complexes metalliques utilises pour le diagnostic et la therapie |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1259497A1 EP1259497A1 (fr) | 2002-11-27 |
EP1259497A4 true EP1259497A4 (fr) | 2004-09-01 |
Family
ID=24059027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01916286A Withdrawn EP1259497A4 (fr) | 2000-03-02 | 2001-02-28 | Nouveaux ligands de la quinoline et complexes metalliques utilises pour le diagnostic et la therapie |
Country Status (5)
Country | Link |
---|---|
US (1) | US6277841B1 (fr) |
EP (1) | EP1259497A4 (fr) |
JP (1) | JP2003525282A (fr) |
AU (1) | AU2001243327A1 (fr) |
WO (1) | WO2001064660A1 (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2408097A1 (fr) | 2000-05-08 | 2001-11-15 | Brainsgate Ltd. | Methode et appareil permettant de stimuler le ganglion spheno-palatien afin de modifier les proprietes de la barriere hemato-encephalique et du debit sanguin cerebral |
US7117033B2 (en) * | 2000-05-08 | 2006-10-03 | Brainsgate, Ltd. | Stimulation for acute conditions |
US7640062B2 (en) | 2000-05-08 | 2009-12-29 | Brainsgate Ltd. | Methods and systems for management of alzheimer's disease |
US7146209B2 (en) * | 2000-05-08 | 2006-12-05 | Brainsgate, Ltd. | Stimulation for treating eye pathologies |
US7684859B2 (en) | 2002-04-25 | 2010-03-23 | Brainsgate Ltd. | Stimulation of the OTIC ganglion for treating medical conditions |
US7561919B2 (en) | 2002-11-14 | 2009-07-14 | Brainsgate Ltd. | SPG stimulation via the greater palatine canal |
JP2006515999A (ja) | 2002-11-14 | 2006-06-15 | ブレインズゲート リミティド | 刺激のための外科用ツール及び技法 |
US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
JP4748791B2 (ja) * | 2003-02-24 | 2011-08-17 | 独立行政法人科学技術振興機構 | 蛍光性ランタニド錯体 |
EP1718342A4 (fr) * | 2004-02-12 | 2009-07-22 | Molecular Insight Pharm Inc | Complexes de technetium-bis(heteroaryl) et de rhenium-bis(heteroaryl) et methodes d'utilisation associees |
US8010189B2 (en) | 2004-02-20 | 2011-08-30 | Brainsgate Ltd. | SPG stimulation for treating complications of subarachnoid hemorrhage |
US8055347B2 (en) | 2005-08-19 | 2011-11-08 | Brainsgate Ltd. | Stimulation for treating brain events and other conditions |
US9233245B2 (en) | 2004-02-20 | 2016-01-12 | Brainsgate Ltd. | SPG stimulation |
US7589209B2 (en) * | 2004-03-23 | 2009-09-15 | New York University | 8-hydroxyquinoline tripodal metal ion probes |
CN101010107A (zh) * | 2004-08-26 | 2007-08-01 | 马林克罗特公司 | 监测肾功能的发光金属络合物 |
US20060094755A1 (en) * | 2004-10-28 | 2006-05-04 | Bioflexis, Llc | Novel quinoline-based metal chelators as antiviral agents |
US7414006B2 (en) * | 2005-03-09 | 2008-08-19 | Exxonmobil Chemical Patents Inc. | Methods for oligomerizing olefins |
WO2006096881A1 (fr) * | 2005-03-09 | 2006-09-14 | Exxonmobil Chemical Patents Inc. | Methodes d’oligomerisation d’olefines |
CN101203248A (zh) * | 2005-06-21 | 2008-06-18 | 马林克罗特公司 | 光学成像造影剂 |
US8003839B2 (en) * | 2006-02-03 | 2011-08-23 | Exxonmobil Chemical Patents Inc. | Process for generating linear apha olefin comonomers |
US7982085B2 (en) * | 2006-02-03 | 2011-07-19 | Exxonmobil Chemical Patents Inc. | In-line process for generating comonomer |
EP1987047B1 (fr) * | 2006-02-03 | 2015-07-01 | ExxonMobil Chemical Patents Inc. | Procédé de génération de comonomères d'alpha-oléfine |
JP2007230877A (ja) * | 2006-02-27 | 2007-09-13 | Keio Gijuku | 発光標識試薬 |
US8404915B2 (en) * | 2006-08-30 | 2013-03-26 | Exxonmobil Chemical Patents Inc. | Phosphine ligand-metal compositions, complexes, and catalysts for ethylene trimerizations |
WO2009022279A2 (fr) * | 2007-08-15 | 2009-02-19 | Koninklijke Philips Electronics N. V. | Quinoléine en tant qu'agent de contraste dans une fluorescence induite par laser (lif) de lésions |
US7860569B2 (en) | 2007-10-18 | 2010-12-28 | Brainsgate, Ltd. | Long-term SPG stimulation therapy for prevention of vascular dementia |
US20120070378A1 (en) * | 2008-12-16 | 2012-03-22 | The University Of Akron | Lanthanide ion complexes and imaging method |
WO2010129258A2 (fr) | 2009-04-27 | 2010-11-11 | Mallinckrodt Inc. | Compositions de scellement tissulaire, dispositifs de fermeture vasculaire et utilisations de ceux-ci |
WO2011112184A1 (fr) | 2010-03-09 | 2011-09-15 | Exxonmobil Chemical Patents Inc. | Système et procédé de trimérisation sélective |
US20120016092A1 (en) * | 2010-07-14 | 2012-01-19 | Sandor Nagy | Catalysts based on quinoline precursors |
US8524972B1 (en) | 2012-04-18 | 2013-09-03 | Exxonmobil Chemical Patents Inc. | Low temperature steam stripping for byproduct polymer and solvent recovery from an ethylene oligomerization process |
EP2878335B1 (fr) | 2013-11-10 | 2018-01-03 | Brainsgate Ltd. | Implant et système d'implantation pour stimulateur neural |
CN104830313B (zh) * | 2015-04-21 | 2017-01-11 | 吉林化工学院 | 一种具有蓝光性能{[Co(5-氨基-8-羟基喹啉)2]·H2O}n配合物的制备方法 |
US10271907B2 (en) | 2015-05-13 | 2019-04-30 | Brainsgate Ltd. | Implant and delivery system for neural stimulator |
EP3334464B1 (fr) | 2015-08-13 | 2024-04-10 | The General Hospital Corporation | Conjugués chélatés à base de manganèse pour l'imagerie par résonance magnétique moléculaire |
CN105949120B (zh) * | 2016-05-27 | 2018-07-24 | 广东工业大学 | 一种四齿螯合型单喹啉衍生物及其制备方法和作为神经退行性疾病的金属离子调节剂的应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE466534B (sv) * | 1988-12-30 | 1992-03-02 | Exploaterings Ab Tbf | Adsorptionsmedel foer metalljoner, proteiner och andra oorganiska och organiska substanser |
US5118499A (en) * | 1991-06-19 | 1992-06-02 | Spyros Theodoropulos | Quinoline polymers, their chelates and process of preparation and use |
JPH11288784A (ja) * | 1998-04-03 | 1999-10-19 | Toray Ind Inc | 発光素子 |
-
2000
- 2000-03-02 US US09/517,252 patent/US6277841B1/en not_active Expired - Fee Related
-
2001
- 2001-02-28 EP EP01916286A patent/EP1259497A4/fr not_active Withdrawn
- 2001-02-28 JP JP2001563501A patent/JP2003525282A/ja active Pending
- 2001-02-28 WO PCT/US2001/006394 patent/WO2001064660A1/fr active Application Filing
- 2001-02-28 AU AU2001243327A patent/AU2001243327A1/en not_active Abandoned
Non-Patent Citations (1)
Title |
---|
No further relevant documents disclosed * |
Also Published As
Publication number | Publication date |
---|---|
WO2001064660A1 (fr) | 2001-09-07 |
JP2003525282A (ja) | 2003-08-26 |
EP1259497A1 (fr) | 2002-11-27 |
AU2001243327A1 (en) | 2001-09-12 |
US6277841B1 (en) | 2001-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020902 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040721 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 07F 13/00 B Ipc: 7A 61P 35/00 B Ipc: 7C 07D 215/26 A Ipc: 7A 61K 31/555 B Ipc: 7A 61P 31/00 B |
|
17Q | First examination report despatched |
Effective date: 20070726 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20100503 |