AU2001243327A1 - Novel quinoline ligands and metal complexes for diagnosis and therapy - Google Patents

Novel quinoline ligands and metal complexes for diagnosis and therapy

Info

Publication number
AU2001243327A1
AU2001243327A1 AU2001243327A AU4332701A AU2001243327A1 AU 2001243327 A1 AU2001243327 A1 AU 2001243327A1 AU 2001243327 A AU2001243327 A AU 2001243327A AU 4332701 A AU4332701 A AU 4332701A AU 2001243327 A1 AU2001243327 A1 AU 2001243327A1
Authority
AU
Australia
Prior art keywords
diagnosis
therapy
metal complexes
novel quinoline
quinoline ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001243327A
Inventor
Samuel I. Achilefu
Joseph E. Bugaj
Richard B. Dorshaw
Raghavan Rajagopalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of AU2001243327A1 publication Critical patent/AU2001243327A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
AU2001243327A 2000-03-02 2001-02-28 Novel quinoline ligands and metal complexes for diagnosis and therapy Abandoned AU2001243327A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09517252 2000-03-02
US09/517,252 US6277841B1 (en) 2000-03-02 2000-03-02 Quinoline ligands and metal complexes for diagnosis and therapy
PCT/US2001/006394 WO2001064660A1 (en) 2000-03-02 2001-02-28 Novel quinoline ligands and metal complexes for diagnosis and therapy

Publications (1)

Publication Number Publication Date
AU2001243327A1 true AU2001243327A1 (en) 2001-09-12

Family

ID=24059027

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001243327A Abandoned AU2001243327A1 (en) 2000-03-02 2001-02-28 Novel quinoline ligands and metal complexes for diagnosis and therapy

Country Status (5)

Country Link
US (1) US6277841B1 (en)
EP (1) EP1259497A4 (en)
JP (1) JP2003525282A (en)
AU (1) AU2001243327A1 (en)
WO (1) WO2001064660A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2408097A1 (en) 2000-05-08 2001-11-15 Brainsgate Ltd. Method and apparatus for stimulating the sphenopalatine ganglion to modify properties of the bbb and cerebral blood flow
US7117033B2 (en) * 2000-05-08 2006-10-03 Brainsgate, Ltd. Stimulation for acute conditions
US7640062B2 (en) 2000-05-08 2009-12-29 Brainsgate Ltd. Methods and systems for management of alzheimer's disease
US7146209B2 (en) * 2000-05-08 2006-12-05 Brainsgate, Ltd. Stimulation for treating eye pathologies
US7684859B2 (en) 2002-04-25 2010-03-23 Brainsgate Ltd. Stimulation of the OTIC ganglion for treating medical conditions
US7561919B2 (en) 2002-11-14 2009-07-14 Brainsgate Ltd. SPG stimulation via the greater palatine canal
JP2006515999A (en) 2002-11-14 2006-06-15 ブレインズゲート リミティド Surgical tools and techniques for stimulation
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
JP4748791B2 (en) * 2003-02-24 2011-08-17 独立行政法人科学技術振興機構 Fluorescent lanthanide complex
EP1718342A4 (en) * 2004-02-12 2009-07-22 Molecular Insight Pharm Inc Technetium-and rhenium-bis(heteroaryl) complexes, and methods of use thereof
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
US7589209B2 (en) * 2004-03-23 2009-09-15 New York University 8-hydroxyquinoline tripodal metal ion probes
CN101010107A (en) * 2004-08-26 2007-08-01 马林克罗特公司 Luminescent metal complexes for monitoring renal function
US20060094755A1 (en) * 2004-10-28 2006-05-04 Bioflexis, Llc Novel quinoline-based metal chelators as antiviral agents
US7414006B2 (en) * 2005-03-09 2008-08-19 Exxonmobil Chemical Patents Inc. Methods for oligomerizing olefins
WO2006096881A1 (en) * 2005-03-09 2006-09-14 Exxonmobil Chemical Patents Inc. Methods for oligomerizing olefins
CN101203248A (en) * 2005-06-21 2008-06-18 马林克罗特公司 Optical imaging contrast agents
US8003839B2 (en) * 2006-02-03 2011-08-23 Exxonmobil Chemical Patents Inc. Process for generating linear apha olefin comonomers
US7982085B2 (en) * 2006-02-03 2011-07-19 Exxonmobil Chemical Patents Inc. In-line process for generating comonomer
EP1987047B1 (en) * 2006-02-03 2015-07-01 ExxonMobil Chemical Patents Inc. Process for generating alpha olefin comonomers
JP2007230877A (en) * 2006-02-27 2007-09-13 Keio Gijuku Luminescent labeling reagent
US8404915B2 (en) * 2006-08-30 2013-03-26 Exxonmobil Chemical Patents Inc. Phosphine ligand-metal compositions, complexes, and catalysts for ethylene trimerizations
WO2009022279A2 (en) * 2007-08-15 2009-02-19 Koninklijke Philips Electronics N. V. Quinoline as contrast agent in laser induced fluorescence (lif) for lesions
US7860569B2 (en) 2007-10-18 2010-12-28 Brainsgate, Ltd. Long-term SPG stimulation therapy for prevention of vascular dementia
US20120070378A1 (en) * 2008-12-16 2012-03-22 The University Of Akron Lanthanide ion complexes and imaging method
WO2010129258A2 (en) 2009-04-27 2010-11-11 Mallinckrodt Inc. Tissue sealant compositions, vascular closure devices, and uses thereof
WO2011112184A1 (en) 2010-03-09 2011-09-15 Exxonmobil Chemical Patents Inc. System and method for selective trimerization
US20120016092A1 (en) * 2010-07-14 2012-01-19 Sandor Nagy Catalysts based on quinoline precursors
US8524972B1 (en) 2012-04-18 2013-09-03 Exxonmobil Chemical Patents Inc. Low temperature steam stripping for byproduct polymer and solvent recovery from an ethylene oligomerization process
EP2878335B1 (en) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant and delivery system for neural stimulator
CN104830313B (en) * 2015-04-21 2017-01-11 吉林化工学院 Preparation method of {[Co(5-amino-8-hydroxyquinoline)2].H2O}n complex with blue light property
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
EP3334464B1 (en) 2015-08-13 2024-04-10 The General Hospital Corporation Manganese-based chelate conjugates for molecular mr imaging
CN105949120B (en) * 2016-05-27 2018-07-24 广东工业大学 A kind of application of four teeth chelating type list quinoline and preparation method thereof and metal ion control agent as neurodegenerative disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE466534B (en) * 1988-12-30 1992-03-02 Exploaterings Ab Tbf ADSORPTIONS FOR METAL IONS, PROTEINS AND OTHER INORGANIC AND ORGANIC SUBSTANCES
US5118499A (en) * 1991-06-19 1992-06-02 Spyros Theodoropulos Quinoline polymers, their chelates and process of preparation and use
JPH11288784A (en) * 1998-04-03 1999-10-19 Toray Ind Inc Luminescent element

Also Published As

Publication number Publication date
WO2001064660A1 (en) 2001-09-07
JP2003525282A (en) 2003-08-26
EP1259497A1 (en) 2002-11-27
EP1259497A4 (en) 2004-09-01
US6277841B1 (en) 2001-08-21

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