EP1189821B1 - Container or capsule for segregated storing of two-component miscible substances - Google Patents
Container or capsule for segregated storing of two-component miscible substances Download PDFInfo
- Publication number
- EP1189821B1 EP1189821B1 EP00923026A EP00923026A EP1189821B1 EP 1189821 B1 EP1189821 B1 EP 1189821B1 EP 00923026 A EP00923026 A EP 00923026A EP 00923026 A EP00923026 A EP 00923026A EP 1189821 B1 EP1189821 B1 EP 1189821B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container
- inner chamber
- capsule
- segregated
- storing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3216—Rigid containers disposed one within the other
Definitions
- the present invention relates to a container or a capsule for the storage of two-component miscible substances, such as medicaments where the one component is the medically active component in liquid, powdery or tablet form while the other component is a liquid such as water for dissolving or diluting the medically active component, the two components to be mixed at a desired or required point of time, wherein the bottom end of the bottom member of the container is closed and is integral with the rest of the bottom member and the mouth of the inner chamber, when the two members of the container are tightly interconnected, is sealingly closed against the bottom of the first member by means of a sealing member.
- two-component miscible substances such as medicaments
- the one component is the medically active component in liquid, powdery or tablet form while the other component is a liquid such as water for dissolving or diluting the medically active component
- US-A-3 856 138 discloses a compartmentalized container for storing, mixing, and dispensing a plurality of incompatible liquids which must be segregated prior to use, which container includes bottom member 1, top member 2, concentric chambers within and around the top member 2, bottom end of bottom member 1 is closed by means of bottom plug 5, mouth 15 sealingly closed to the first member 1 by means of a sealing member 17.
- the bottom member 1 is closed by a different piece 5.
- Neither the above described container nor the other containers known in the prior art are suitable for rapid access to a mixed ready-to-use medicament, composed of separately stored components, for use by healthy persons or patients, such as for example cardiac patients.
- the container or capsule comprises a bottom member and a top member, and two concentric chambers, the outer chamber extending from the bottom of the bottom member and opening towards the top member whereas the inner chamber extends from the top member and having its mouth facing the bottom of the bottom member.
- the container or the capsule according to the invention is characterized in that the mouth of the inner chamber, when the bottom and top members are tightly interconnected, is sealingly closed to the bottom member by means of a sealing member.
- the drawing shows an axial section through a capsule comprising a bottom member 1 and a top member 2 which together define an outer chamber 11 and, concentrically therewith, an inner chamber 12.
- the outer chamber 11 extends from the bottom of the bottom member 1 and opens towards the top member 2.
- the inner chamber 11 extends from the top member 2 towards the bottom of the bottom member 1.
- the bottom member 1 and the top member 2 are interconnectable through threads 3, the threading being further sealed by means of an O-ring 4.
- the inner chamber 12 has such a length that its mouth will seal against the bottom of the bottom member 1, a sealing member 13 being provided which does also act as a plug for closing the inner chamber 12.
- the outer chamber 11 is provided for receiving a predetermined quantity of a substance in liquid, powdery or tablet form which up to a given point of time should be kept separate from a predetermined quantity of liquid received in the inner chamber 12 and which at a such given time should be mixed with the liquid from the inner chamber.
- the mixing is achieved by removing the top member 2 from the bottom member 1 the mouth of the inner chamber 12 thereby being uncovered so that the liquid in the inner chamber 12 mixes with the contents of the outer chamber 11.
- a specific example of purpose of the invention is that a cardiac medicine in the form of a powder or an easily dissolvable tablet is kept in the outer chamber 11 while water is kept in the inner chamber 12, the water and the cardiac medicine being mixed only at the time when the user of the capsule suffers an acute cardiac emergency.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Package Specialized In Special Use (AREA)
- Packages (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Closures For Containers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO992128 | 1999-05-03 | ||
NO992128A NO309761B1 (no) | 1999-05-03 | 1999-05-03 | Beholder eller kapsel for adskilt oppbevaring av to- komponents blandbare materialer |
PCT/NO2000/000147 WO2000066456A2 (en) | 1999-05-03 | 2000-05-02 | Container or capsule for segregated storing of two-component miscible substances |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1189821A1 EP1189821A1 (en) | 2002-03-27 |
EP1189821B1 true EP1189821B1 (en) | 2003-03-12 |
Family
ID=19903279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00923026A Expired - Lifetime EP1189821B1 (en) | 1999-05-03 | 2000-05-02 | Container or capsule for segregated storing of two-component miscible substances |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1189821B1 (no) |
JP (1) | JP2003525071A (no) |
AT (1) | ATE234241T1 (no) |
AU (1) | AU4321200A (no) |
CA (1) | CA2372502A1 (no) |
DE (1) | DE60001656T2 (no) |
NO (1) | NO309761B1 (no) |
WO (1) | WO2000066456A2 (no) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP20211761T1 (hr) * | 2016-06-28 | 2022-02-18 | Asamedic As | Dvokomponentna kompozicija koja sadrži acetilsalicilnu kiselinu |
EP3501523A1 (en) | 2017-12-22 | 2019-06-26 | Asamedic AS | Two-component compositions comprising acetyl salicylic acid and a carbonate salt |
EP3501522A1 (en) | 2017-12-22 | 2019-06-26 | Asamedic AS | Compositions comprising acetylsalicylic acid and a phosphate salt |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3856138A (en) * | 1973-05-31 | 1974-12-24 | Shionogi & Co | Compartmentalized container |
GB2235897A (en) * | 1989-09-15 | 1991-03-20 | Plaspharm | Plastics dispenser body having injection and blow moulded parts. |
DK171362B1 (da) * | 1996-01-26 | 1996-09-23 | Gea Farmaceutisk Fabrik As | Apparat til dispensering af øjendråber |
-
1999
- 1999-05-03 NO NO992128A patent/NO309761B1/no not_active IP Right Cessation
-
2000
- 2000-05-02 AU AU43212/00A patent/AU4321200A/en not_active Abandoned
- 2000-05-02 AT AT00923026T patent/ATE234241T1/de not_active IP Right Cessation
- 2000-05-02 DE DE60001656T patent/DE60001656T2/de not_active Expired - Fee Related
- 2000-05-02 EP EP00923026A patent/EP1189821B1/en not_active Expired - Lifetime
- 2000-05-02 JP JP2000615301A patent/JP2003525071A/ja not_active Withdrawn
- 2000-05-02 WO PCT/NO2000/000147 patent/WO2000066456A2/en active IP Right Grant
- 2000-05-02 CA CA002372502A patent/CA2372502A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NO992128L (no) | 2000-11-06 |
NO309761B1 (no) | 2001-03-26 |
NO992128D0 (no) | 1999-05-03 |
DE60001656T2 (de) | 2003-12-18 |
WO2000066456A3 (en) | 2007-10-25 |
DE60001656D1 (de) | 2003-04-17 |
AU4321200A (en) | 2000-11-17 |
EP1189821A1 (en) | 2002-03-27 |
JP2003525071A (ja) | 2003-08-26 |
ATE234241T1 (de) | 2003-03-15 |
CA2372502A1 (en) | 2000-11-09 |
WO2000066456A2 (en) | 2000-11-09 |
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