WO2000066456A2 - Container or capsule for segregated storing of two-component miscible substances - Google Patents

Container or capsule for segregated storing of two-component miscible substances Download PDF

Info

Publication number
WO2000066456A2
WO2000066456A2 PCT/NO2000/000147 NO0000147W WO0066456A2 WO 2000066456 A2 WO2000066456 A2 WO 2000066456A2 NO 0000147 W NO0000147 W NO 0000147W WO 0066456 A2 WO0066456 A2 WO 0066456A2
Authority
WO
WIPO (PCT)
Prior art keywords
inner chamber
container
capsule
segregated
storing
Prior art date
Application number
PCT/NO2000/000147
Other languages
French (fr)
Other versions
WO2000066456A3 (en
Inventor
Anders Älveborn
Per Erik Stribolt Halvorsen
Original Assignee
Aelveborn Anders
Per Erik Stribolt Halvorsen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aelveborn Anders, Per Erik Stribolt Halvorsen filed Critical Aelveborn Anders
Priority to AU43212/00A priority Critical patent/AU4321200A/en
Priority to EP00923026A priority patent/EP1189821B1/en
Priority to DE60001656T priority patent/DE60001656T2/en
Priority to JP2000615301A priority patent/JP2003525071A/en
Priority to AT00923026T priority patent/ATE234241T1/en
Priority to CA002372502A priority patent/CA2372502A1/en
Publication of WO2000066456A2 publication Critical patent/WO2000066456A2/en
Publication of WO2000066456A3 publication Critical patent/WO2000066456A3/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3216Rigid containers disposed one within the other

Definitions

  • the present invention relates to a container or a capsule for the storage of two- component miscible substances, such as medicaments where the one component is the medically active component in liquid, powdery or tablet form while the other component is a liquid such as water for dissolving or diluting the medically active component, the two components to be mixed at a desired or required point of time.
  • the container or capsule comprises a bottom member and a top member, and two concentric chambers, the outer chamber extending from the bottom of the bottom member and opening towards the top member whereas the inner chamber extends from the top member and having its mouth facing the bottom of the bottom member.
  • the container or the capsule according to the invention is characterized in that the mouth of the inner chamber, when the bottom and top members are tightly interconnected, is sealingly closed to the bottom member by means of a sealing member.
  • the drawing shows an axial section through a capsule comprising a bottom member 1 and a top member 2 which together define an outer chamber 11 and, concentrically therewith, an inner chamber 12.
  • the outer chamber 1 1 extends from the bottom of the bottom member 1 and opens towards the top member 2.
  • the inner chamber 1 1 extends from the top member 2 towards the bottom of the bottom member 1.
  • the bottom member 1 and the top member 2 are interconnectable through threads 3, the threading being further sealed by means of an O-ring 4.
  • the inner chamber 12 has such a length that its mouth will seal against the bottom of the bottom member 1, a sealing member 13 being provided which does also act as a plug for closing the inner chamber 12.
  • the outer chamber 11 is provided for receiving a predetermined quantity of a substance in liquid, powdery or tablet form which up to a given point of time should be kept separate from a predetermined quantity of liquid received in the inner chamber 12 and which at a such given time should be mixed with the liquid from the inner chamber.
  • the mixing is achieved by removing the top member 2 from the bottom member 1 the mouth of the inner chamber 12 thereby being uncovered so that the liquid in the inner chamber 12 mixes with the contents of the outer chamber 1 1.
  • a specific example of purpose of the invention is that a cardiac medicine in the form of a powder or an easily dissolvable tablet is kept in the outer chamber 1 1 while water is kept in the inner chamber 12, the water and the cardiac medicine being mixed only at the time when the user of the capsule suffers an acute cardiac emergency.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Package Specialized In Special Use (AREA)
  • Packages (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Closures For Containers (AREA)

Abstract

A container or capsule for segregated storing of two-component miscible substances comprises a bottom member (1) and a top member (2), and two concentric chambers (11, 12), the outer chamber (11) extending from the bottom of the bottom member (1) and opening towards the top member (2) whereas the inner chamber (12) being integral with the top member has its mouth facing the bottom of the bottom member. The mouth of the inner chamber (12) is sealingly closed to the bottom member by means of a sealing member (13) when the bottom and top members (1, 2) are tightly interconnected. The sealing member (13) of the inner chamber (12) constitutes a plug for closing the said inner chamber prior to bringing the two members (1, 2) together for segregated storing of the two components.

Description

Container or capsule for segregated storing of two-component miscible substances
The present invention relates to a container or a capsule for the storage of two- component miscible substances, such as medicaments where the one component is the medically active component in liquid, powdery or tablet form while the other component is a liquid such as water for dissolving or diluting the medically active component, the two components to be mixed at a desired or required point of time.
For both patients and healthy persons there is a need for a small and simply operated container which contains two component medicaments to be stored separately and mixed only at the time of need.
In the prior art such containers or capsules are described both for use with pain killers, in the art of dental techniques and in the art of cosmetics. One such container is described in the Norwegian patent no. 156123, based on PCT/EP82/00032. This is a container comprised of two concentric containers, screewed together such that the open end of the inner container, defining an inner compartment, is pressed towards a sealing rim constituting an elevation on the closed bottom of the outer container, defining the outer compartment. This container lacks, however, a sealing member in the open end of the inner chamber which also functions as a plug, closing this chamber. Neither the above described container nor the other containers known in the prior art are suitable for rapid access to a mixed ready-to-use medicament, composed of separately stored components, for use by healthy persons or patients, such as for example cardiac patients.
This aspect is obtained by the present invention characterized by the enclosed claims.
For cardiac patients it may be necessary to have an easily accessible emergency supply of cardiac medicament for the case that the patient suffers an acute situation, and for such circumstances the container or capsule according to this invention is provided. The container or capsule comprises a bottom member and a top member, and two concentric chambers, the outer chamber extending from the bottom of the bottom member and opening towards the top member whereas the inner chamber extends from the top member and having its mouth facing the bottom of the bottom member. The container or the capsule according to the invention is characterized in that the mouth of the inner chamber, when the bottom and top members are tightly interconnected, is sealingly closed to the bottom member by means of a sealing member. Further features of the invention will appear from the following description and from the patent claims.
The invention shall now be described with reference to the accompanying drawing showing an axial section through an embodiment of a capsule according to the invention.
The drawing shows an axial section through a capsule comprising a bottom member 1 and a top member 2 which together define an outer chamber 11 and, concentrically therewith, an inner chamber 12. The outer chamber 1 1 extends from the bottom of the bottom member 1 and opens towards the top member 2. The inner chamber 1 1 extends from the top member 2 towards the bottom of the bottom member 1. The bottom member 1 and the top member 2 are interconnectable through threads 3, the threading being further sealed by means of an O-ring 4. The inner chamber 12 has such a length that its mouth will seal against the bottom of the bottom member 1, a sealing member 13 being provided which does also act as a plug for closing the inner chamber 12.
In operation, the outer chamber 11 is provided for receiving a predetermined quantity of a substance in liquid, powdery or tablet form which up to a given point of time should be kept separate from a predetermined quantity of liquid received in the inner chamber 12 and which at a such given time should be mixed with the liquid from the inner chamber. The mixing is achieved by removing the top member 2 from the bottom member 1 the mouth of the inner chamber 12 thereby being uncovered so that the liquid in the inner chamber 12 mixes with the contents of the outer chamber 1 1.
A specific example of purpose of the invention is that a cardiac medicine in the form of a powder or an easily dissolvable tablet is kept in the outer chamber 1 1 while water is kept in the inner chamber 12, the water and the cardiac medicine being mixed only at the time when the user of the capsule suffers an acute cardiac emergency.

Claims

PATENT CLAIMS
1. Container or capsule for the storage of two-component miscible substances, comprising a bottom member (1) and a top member (2), and two concentric chambers (1 1; 12), the outer chamber (1 1) extending from the bottom of one of said members, e.g. the bottom member (1), and is open towards the other member whereas the inner chamber (12) being integral with the said other member has its mouth facing the bottom of the said first member, characterized in that the mouth of the inner chamber (12), when the two members (1, 2) of the container or capsule are tightly interconnected, is sealingly closed to the said first member by means of a sealing member (13).
2. Container or capsule as claimed in claim 1 , characterized in that the sealing member (13) of the inner chamber (12) constitutes a plug for closing the said inner chamber prior to bringing the two members (1 , 2) together for segregated storing of the two components.
PCT/NO2000/000147 1999-05-03 2000-05-02 Container or capsule for segregated storing of two-component miscible substances WO2000066456A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU43212/00A AU4321200A (en) 1999-05-03 2000-05-02 Container or capsule for segregated storing of two-component miscible substances
EP00923026A EP1189821B1 (en) 1999-05-03 2000-05-02 Container or capsule for segregated storing of two-component miscible substances
DE60001656T DE60001656T2 (en) 1999-05-03 2000-05-02 CONTAINER FOR THE SEPARATE STORAGE OF TWO MIXABLE COMPONENTS
JP2000615301A JP2003525071A (en) 1999-05-03 2000-05-02 Containers or capsules for separation and storage of binary miscible substances
AT00923026T ATE234241T1 (en) 1999-05-03 2000-05-02 CONTAINER FOR STORING TWO MIXABLE COMPONENTS SEPARATELY
CA002372502A CA2372502A1 (en) 1999-05-03 2000-05-02 Container or capsule for segregated storing of two-component miscible substances

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO992128A NO309761B1 (en) 1999-05-03 1999-05-03 Container or capsule for separate storage of two-component miscible materials
NO19992128 1999-05-03

Publications (2)

Publication Number Publication Date
WO2000066456A2 true WO2000066456A2 (en) 2000-11-09
WO2000066456A3 WO2000066456A3 (en) 2007-10-25

Family

ID=19903279

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NO2000/000147 WO2000066456A2 (en) 1999-05-03 2000-05-02 Container or capsule for segregated storing of two-component miscible substances

Country Status (8)

Country Link
EP (1) EP1189821B1 (en)
JP (1) JP2003525071A (en)
AT (1) ATE234241T1 (en)
AU (1) AU4321200A (en)
CA (1) CA2372502A1 (en)
DE (1) DE60001656T2 (en)
NO (1) NO309761B1 (en)
WO (1) WO2000066456A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018002124A1 (en) * 2016-06-28 2018-01-04 Asamedic As Two-component composition
US11844806B2 (en) 2017-12-22 2023-12-19 Asamedic As Compositions comprising acetylsalicylic acid and a phosphate salt
US11850253B2 (en) 2017-12-22 2023-12-26 Asamedic As Two component compositions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856138A (en) * 1973-05-31 1974-12-24 Shionogi & Co Compartmentalized container
EP0417998A1 (en) * 1989-09-15 1991-03-20 Merck & Co. Inc. Fluid dispensing device
DK171362B1 (en) * 1996-01-26 1996-09-23 Gea Farmaceutisk Fabrik As Device for dispensing eye drops

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856138A (en) * 1973-05-31 1974-12-24 Shionogi & Co Compartmentalized container
EP0417998A1 (en) * 1989-09-15 1991-03-20 Merck & Co. Inc. Fluid dispensing device
DK171362B1 (en) * 1996-01-26 1996-09-23 Gea Farmaceutisk Fabrik As Device for dispensing eye drops

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018002124A1 (en) * 2016-06-28 2018-01-04 Asamedic As Two-component composition
US11369581B2 (en) 2016-06-28 2022-06-28 Asamedic As Two component composition
US11918554B2 (en) 2016-06-28 2024-03-05 Asamedic As Two-component composition
US11844806B2 (en) 2017-12-22 2023-12-19 Asamedic As Compositions comprising acetylsalicylic acid and a phosphate salt
US11850253B2 (en) 2017-12-22 2023-12-26 Asamedic As Two component compositions

Also Published As

Publication number Publication date
EP1189821A1 (en) 2002-03-27
ATE234241T1 (en) 2003-03-15
DE60001656D1 (en) 2003-04-17
CA2372502A1 (en) 2000-11-09
JP2003525071A (en) 2003-08-26
NO309761B1 (en) 2001-03-26
NO992128D0 (en) 1999-05-03
NO992128L (en) 2000-11-06
WO2000066456A3 (en) 2007-10-25
EP1189821B1 (en) 2003-03-12
AU4321200A (en) 2000-11-17
DE60001656T2 (en) 2003-12-18

Similar Documents

Publication Publication Date Title
US4994056A (en) Unit dose medicament storing and mixing system
US6113257A (en) Two-compartment container
US4610684A (en) Flexible container and mixing system for storing and preparing I.V. fluids
JP3561741B2 (en) Container with two or more compartments
US4731053A (en) Container device for separately storing and mixing two ingredients
US4182447A (en) Device for storing, transporting and mixing reactive ingredients
EA005847B1 (en) Multi-compartment container assembly system
CA2558473C (en) A cartridge unit for a multi-compartment container assembly
EP0533171A1 (en) Transfusion device
US8136660B2 (en) Multi compartment container system
US6957909B1 (en) Blister pack
US5257986A (en) Container for the separate sterile storage of at least two substances and for mixing said substances
JP2003135563A (en) Small bag-shaped medicine container
WO2013156808A1 (en) Reusable or one time use multi-compartment mixing and dispensing applicator tube or special spouted pouch with a sliding clamp
US5407437A (en) Closure of a medicament well
EP2576370A2 (en) A container having two or more compartments
US20170296001A1 (en) Container unit comprising two containers
EP0327519A1 (en) An appliance for the mixing and/or transfer of a substance
US3860114A (en) Multi-chamber container
EP3010826A1 (en) Container and method for the storage and extemporaneous reconstitution of a mixture of compounds in fixed proportions
EP1189821B1 (en) Container or capsule for segregated storing of two-component miscible substances
CN107073219A (en) Double-chamber syringe
JPH1129180A (en) Mixing container
KR200338755Y1 (en) Toilet articles a vessel
EP1084692B1 (en) Liquid container

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 00806729.5

Country of ref document: CN

ENP Entry into the national phase

Ref document number: 2372502

Country of ref document: CA

Ref document number: 2372502

Country of ref document: CA

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2000 615301

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2000923026

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09959163

Country of ref document: US

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 2000923026

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2000923026

Country of ref document: EP