EP1161237A4 - PROTEASE INHIBITORS - Google Patents

PROTEASE INHIBITORS

Info

Publication number
EP1161237A4
EP1161237A4 EP00917997A EP00917997A EP1161237A4 EP 1161237 A4 EP1161237 A4 EP 1161237A4 EP 00917997 A EP00917997 A EP 00917997A EP 00917997 A EP00917997 A EP 00917997A EP 1161237 A4 EP1161237 A4 EP 1161237A4
Authority
EP
European Patent Office
Prior art keywords
protease inhibitors
protease
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00917997A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1161237A1 (en
Inventor
Scott Kevin Thompson
Daniel Frank Veber
Stacie Marie Halbert
Sirishkumar Nidamarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1161237A1 publication Critical patent/EP1161237A1/en
Publication of EP1161237A4 publication Critical patent/EP1161237A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/04—Seven-membered rings not condensed with other rings
    • C07D321/06—1,3-Dioxepines; Hydrogenated 1,3-dioxepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EP00917997A 1999-03-16 2000-03-16 PROTEASE INHIBITORS Withdrawn EP1161237A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12465999P 1999-03-16 1999-03-16
US124659P 1999-03-16
PCT/US2000/006888 WO2000054769A1 (en) 1999-03-16 2000-03-16 Protease inhibitors

Publications (2)

Publication Number Publication Date
EP1161237A1 EP1161237A1 (en) 2001-12-12
EP1161237A4 true EP1161237A4 (en) 2002-03-27

Family

ID=22416114

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00917997A Withdrawn EP1161237A4 (en) 1999-03-16 2000-03-16 PROTEASE INHIBITORS

Country Status (9)

Country Link
EP (1) EP1161237A4 (es)
JP (1) JP2002539160A (es)
AR (1) AR022927A1 (es)
AU (1) AU3888200A (es)
CO (1) CO5180542A1 (es)
HK (1) HK1043534A1 (es)
PE (1) PE20001564A1 (es)
UY (1) UY26026A1 (es)
WO (1) WO2000054769A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US6583137B1 (en) 1999-11-10 2003-06-24 Smithkline Beecham Corporation Protease inhibitors
JP2003513924A (ja) 1999-11-10 2003-04-15 スミスクライン・ビーチャム・コーポレイション プロテア−ゼ阻害剤
EP1232155A4 (en) 1999-11-10 2002-11-20 Smithkline Beecham Corp PROTEASE INHIBITORS
NZ520588A (en) 2000-03-21 2004-06-25 Smithkline Beecham Corp Protease inhibitors
EP1465862A1 (en) 2002-01-17 2004-10-13 SmithKline Beecham Corporation Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors
JP2004196696A (ja) * 2002-12-18 2004-07-15 Kyowa Hakko Kogyo Co Ltd 関節炎の予防剤または治療剤
WO2012166458A1 (en) * 2011-05-27 2012-12-06 Lexicon Pharmaceuticals, Inc. 4h-thieno[3,2-c]chromene-based inhibitors of notum pectinacetylesterase and methods of their use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004172A1 (en) * 1992-08-20 1994-03-03 Prototek, Inc. Peptidyl activated ketone inhibitors containing natural and unnatural peptide sequences
EP0603769A1 (en) * 1992-12-25 1994-06-29 Mitsubishi Chemical Corporation Alpha-Aminoketone derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004172A1 (en) * 1992-08-20 1994-03-03 Prototek, Inc. Peptidyl activated ketone inhibitors containing natural and unnatural peptide sequences
EP0603769A1 (en) * 1992-12-25 1994-06-29 Mitsubishi Chemical Corporation Alpha-Aminoketone derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0054769A1 *

Also Published As

Publication number Publication date
UY26026A1 (es) 2000-10-31
WO2000054769A1 (en) 2000-09-21
JP2002539160A (ja) 2002-11-19
AU3888200A (en) 2000-10-04
HK1043534A1 (zh) 2002-09-20
EP1161237A1 (en) 2001-12-12
CO5180542A1 (es) 2002-07-30
PE20001564A1 (es) 2001-02-08
AR022927A1 (es) 2002-09-04

Similar Documents

Publication Publication Date Title
PL349192A1 (en) Protease inhibitors
GB9912961D0 (en) Metalloprotease inhibitors
IL150964A0 (en) Protease inhibitors
EP1093367A4 (en) PROTEASE INHIBITORS
PL350452A1 (en) Dihetero-substituted metalloprotease inhibitors
EP1067894A4 (en) PROTHEASEINHIBITOREN
EP1235577A4 (en) PROTEASE INHIBITORS
EP1079821A4 (en) PROTEASE INHIBITORS
IL153421A0 (en) Protease inhibitors
EP1232155A4 (en) PROTEASE INHIBITORS
EP1229912A4 (en) PROTEASE INHIBITORS
EP1231921A4 (en) PROTEASE INHIBITORS
EP1229915A4 (en) PROTEASE INHIBITORS
EP1229914A4 (en) PROTEASE INHIBITORS
EP1140897A4 (en) PROTEASE INHIBITORS
EP1086083A4 (en) PROTEASE INHIBITORS
IL151087A0 (en) Protease inhibitors
EP1161237A4 (en) PROTEASE INHIBITORS
EP1351930A4 (en) PROTEASE INHIBITORS
HK1044758A1 (zh) 蛋白酶抑制劑
EP1233771A4 (en) PROTEASE INHIBITORS
EP1229911A4 (en) PROTEASE INHIBITORS
EP1231923A4 (en) PROTEASE INHIBITORS
EP1231922A4 (en) PROTEASE INHIBITORS
EP1232154A4 (en) PROTEASE INHIBITORS

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010914

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20020212

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7A 61K 31/357 A, 7C 07D 321/06 B, 7C 07D 407/12 B, 7C 07D 409/12 B, 7C 07D 495/14 B

17Q First examination report despatched

Effective date: 20020523

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20021003

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1043534

Country of ref document: HK