EP1159619A2 - Nouvelles techniques permettant de traiter et de diagnostiquer le cancer du sein, compositions et techniques de criblage pour modulateurs de cancer du sein - Google Patents
Nouvelles techniques permettant de traiter et de diagnostiquer le cancer du sein, compositions et techniques de criblage pour modulateurs de cancer du seinInfo
- Publication number
- EP1159619A2 EP1159619A2 EP00916419A EP00916419A EP1159619A2 EP 1159619 A2 EP1159619 A2 EP 1159619A2 EP 00916419 A EP00916419 A EP 00916419A EP 00916419 A EP00916419 A EP 00916419A EP 1159619 A2 EP1159619 A2 EP 1159619A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- breast cancer
- protein
- bch1
- expression
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 230000000699 topical effect Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
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- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des techniques utilisées pour diagnostiquer et pronostiquer le cancer du sein. L'invention concerne également des techniques pouvant être utilisées pour cribler des agents bioactifs candidats, permettant de moduler le cancer du sein. L'invention concerne, en outre, des techniques et des cibles moléculaires (gènes et leurs produits) permettant d'intervenir thérapeutiquement dans le cancer du sein et dans d'autres cancers.
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US440493 | 1989-11-22 | ||
| US26886599A | 1999-03-15 | 1999-03-15 | |
| US268865 | 1999-03-15 | ||
| US43987899A | 1999-11-12 | 1999-11-12 | |
| US44037099A | 1999-11-12 | 1999-11-12 | |
| US440370 | 1999-11-12 | ||
| US439878 | 1999-11-12 | ||
| US44049399A | 1999-11-15 | 1999-11-15 | |
| US44067799A | 1999-11-16 | 1999-11-16 | |
| US44067699A | 1999-11-16 | 1999-11-16 | |
| US440676 | 1999-11-16 | ||
| US440677 | 1999-11-16 | ||
| US45081099A | 1999-11-29 | 1999-11-29 | |
| US450810 | 1999-11-29 | ||
| US45313799A | 1999-12-02 | 1999-12-02 | |
| PCT/US2000/006952 WO2000055629A2 (fr) | 1999-03-15 | 2000-03-15 | Nouvelles techniques permettant de traiter et de diagnostiquer le cancer du sein, compositions et techniques de criblage pour modulateurs de cancer du sein |
| US453137 | 2003-06-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP1159619A2 true EP1159619A2 (fr) | 2001-12-05 |
Family
ID=27575318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP00916419A Withdrawn EP1159619A2 (fr) | 1999-03-15 | 2000-03-15 | Nouvelles techniques permettant de traiter et de diagnostiquer le cancer du sein, compositions et techniques de criblage pour modulateurs de cancer du sein |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1159619A2 (fr) |
| AU (1) | AU3752700A (fr) |
| CA (1) | CA2368152A1 (fr) |
| WO (1) | WO2000055629A2 (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69939874D1 (de) | 1998-09-02 | 2008-12-18 | Diadexus Inc | Verfahren zur diagnose, bewertung sowie bilddarstellung verschiedener krebserkrankungen |
| US6902892B1 (en) | 1998-10-19 | 2005-06-07 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| US6962980B2 (en) | 1999-09-24 | 2005-11-08 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| US7888477B2 (en) | 1998-12-17 | 2011-02-15 | Corixa Corporation | Ovarian cancer-associated antibodies and kits |
| US6468546B1 (en) | 1998-12-17 | 2002-10-22 | Corixa Corporation | Compositions and methods for therapy and diagnosis of ovarian cancer |
| WO2001035811A2 (fr) * | 1999-11-16 | 2001-05-25 | Eos Biotechnology, Inc. | Nouvelles methodes diagnostiques et pronostiques du cancer du sein, compositions et procedes de criblage de modulateurs de cancer du sein |
| EP1267934A4 (fr) * | 1999-11-23 | 2004-03-17 | Diadexus Inc | Nouvelle methode de diagnostic, de surveillance, de stadification, d'imagerie et de traitement du cancer du sein |
| US7238471B1 (en) | 1999-11-23 | 2007-07-03 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating breast cancer |
| US7285382B2 (en) | 2000-01-25 | 2007-10-23 | Genentech, Inc. | Compositions and methods for treatment of cancer |
| US7534417B2 (en) | 2000-02-24 | 2009-05-19 | Agensys, Inc. | 103P2D6: tissue specific protein highly expressed in various cancers |
| GB0004576D0 (en) * | 2000-02-25 | 2000-04-19 | Oxford Glycosciences Uk Ltd | Proteins |
| WO2001072826A2 (fr) * | 2000-03-24 | 2001-10-04 | Genzyme Corporation | Gene 1 associe a l'osteomalacie oncogene |
| US7108977B2 (en) * | 2000-05-19 | 2006-09-19 | Hoffmann-La Roche Inc. | Process for determining the tumoricidal potential of a sample the use of a nucleic acid which is downregulated in human tumor cells |
| US20030148920A1 (en) * | 2000-12-27 | 2003-08-07 | Steven Rosen | Sulfatases and methods of use thereof |
| US20060063230A1 (en) | 2000-12-27 | 2006-03-23 | Roman Naworth | Sulfatases and methods of use thereof |
| WO2002074906A2 (fr) * | 2001-03-16 | 2002-09-26 | Eli Lilly And Company | Proteines de mammiferes lp et reactifs associes |
| US6461847B1 (en) * | 2001-03-19 | 2002-10-08 | Applera Corporation | Polynucleotides encoding human estrone sulfatases |
| EP1470239B1 (fr) * | 2001-12-31 | 2009-12-30 | Dana-Farber Cancer Institute, Inc. | Expression de la psoriasine par les cellules epitheliales mammaires |
| EP3115470B1 (fr) | 2002-03-13 | 2018-07-18 | Genomic Health, Inc. | Profilage de l'expression génétique dans des tissus de tumeurs prélevées par biopsie |
| CA2527571A1 (fr) | 2003-05-29 | 2004-12-09 | Millennium Pharmaceuticals, Inc. | Compositions, kits et procedes d'identification, d'evaluation et de prevention, et therapie anticancereuse |
| US7666583B2 (en) | 2004-02-19 | 2010-02-23 | Yale University | Identification of cancer protein biomarkers using proteomic techniques |
| US7899623B2 (en) * | 2004-09-22 | 2011-03-01 | Tripath Imaging, Inc. | Methods and computer program products for analysis and optimization of marker candidates for cancer prognosis |
| JP5095416B2 (ja) | 2005-12-06 | 2012-12-12 | 協和発酵キリン株式会社 | 抗ｐｅｒｐ遺伝子組換え抗体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993003741A1 (fr) * | 1991-08-22 | 1993-03-04 | Becton, Dickinson & Company | Procedes et compositions de traitements de cancers et de pronostic de reactions auxdits traitements |
| EP0939824B1 (fr) * | 1996-10-31 | 2007-06-06 | Abbott Laboratories | Reactifs et procedes pour le depistage de pathologies mammaires |
| WO1998034118A1 (fr) * | 1997-01-30 | 1998-08-06 | Yale University | Methodes diagnostiques et compositions basees sur la repartition de rad51 |
| CA2308029A1 (fr) * | 1997-10-31 | 1999-05-14 | Abbott Laboratories | Reactifs et procedes utiles pour deceler les pathologies mammaires |
| EP1032706A1 (fr) * | 1997-11-18 | 2000-09-06 | Abbott Laboratories | Reactifs et procedes utiles pour detecter des maladies de la poitrine |
| JP2002507387A (ja) * | 1997-12-24 | 2002-03-12 | コリクサ コーポレイション | 乳癌の免疫療法および診断のための化合物ならびにそれらの使用のための方法 |
| CA2347906A1 (fr) * | 1998-08-04 | 2000-02-17 | Diadexus, Inc. | Nouvelle methode permettant de diagnostiquer, de surveiller le cancer du sein, d'en determiner le stade ainsi que d'en former des images et de le traiter |
-
2000
- 2000-03-15 AU AU37527/00A patent/AU3752700A/en not_active Abandoned
- 2000-03-15 CA CA002368152A patent/CA2368152A1/fr not_active Abandoned
- 2000-03-15 EP EP00916419A patent/EP1159619A2/fr not_active Withdrawn
- 2000-03-15 WO PCT/US2000/006952 patent/WO2000055629A2/fr not_active Application Discontinuation
Non-Patent Citations (1)
| Title |
|---|
| See references of WO0055629A3 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000055629A3 (fr) | 2001-03-22 |
| CA2368152A1 (fr) | 2000-09-21 |
| AU3752700A (en) | 2000-10-04 |
| WO2000055629A2 (fr) | 2000-09-21 |
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