CA2369319A1 - Methodes permettant de diagnostiquer du cancer colo-rectal, compositions, et methodes permettant de detecter des modulateurs du cancer colo-rectal - Google Patents

Methodes permettant de diagnostiquer du cancer colo-rectal, compositions, et methodes permettant de detecter des modulateurs du cancer colo-rectal Download PDF

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Publication number
CA2369319A1
CA2369319A1 CA002369319A CA2369319A CA2369319A1 CA 2369319 A1 CA2369319 A1 CA 2369319A1 CA 002369319 A CA002369319 A CA 002369319A CA 2369319 A CA2369319 A CA 2369319A CA 2369319 A1 CA2369319 A1 CA 2369319A1
Authority
CA
Canada
Prior art keywords
crc
protein
antibody
fragment
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002369319A
Other languages
English (en)
Inventor
David Mack
Kurt C. Gish
Keith E. Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EOS Biotechnology Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/268,866 external-priority patent/US6316272B1/en
Priority claimed from US09/436,983 external-priority patent/US6294343B1/en
Priority claimed from US09/435,945 external-priority patent/US6773878B1/en
Application filed by Individual filed Critical Individual
Publication of CA2369319A1 publication Critical patent/CA2369319A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Abstract

L'invention concerne des méthodes utiles pour le diagnostic et le pronostic du cancer colo-rectal. L'invention concerne également des méthodes permettant de détecter la capacité que possèdent des agents bioactifs candidats pour moduler un cancer colo-rectal. L'invention concerne en outre des méthodes et des cibles moléculaires (gènes et leurs produits) permettant d'effectuer une intervention thérapeutique pour lutter contre le cancer colo-rectal et d'autres types cancers.
CA002369319A 1999-03-15 2000-03-15 Methodes permettant de diagnostiquer du cancer colo-rectal, compositions, et methodes permettant de detecter des modulateurs du cancer colo-rectal Abandoned CA2369319A1 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US09/268,866 US6316272B1 (en) 1999-03-15 1999-03-15 Methods of diagnosis of colorectal cancer and methods of screening for colorectal cancer modulators
US09/268,866 1999-03-15
US09/436,983 US6294343B1 (en) 1999-11-09 1999-11-09 Methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators
US09/436,983 1999-11-09
US09/435,945 US6773878B1 (en) 1999-11-09 1999-11-09 Methods of diagnosing of colorectal cancer, compositions, and methods of screening for colorectal cancer modulators
US09/435,945 1999-11-09
US45085799A 1999-11-29 1999-11-29
US09/450,857 1999-11-29
US45385099A 1999-12-02 1999-12-02
US09/453,850 1999-12-02
US49344400A 2000-01-28 2000-01-28
US09/493,444 2000-01-28
PCT/US2000/007044 WO2000055633A2 (fr) 1999-03-15 2000-03-15 Methodes permettant de diagnostiquer du cancer colo-rectal, compositions, et methodes permettant de detecter des modulateurs du cancer colo-rectal

Publications (1)

Publication Number Publication Date
CA2369319A1 true CA2369319A1 (fr) 2000-09-21

Family

ID=27559474

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002369319A Abandoned CA2369319A1 (fr) 1999-03-15 2000-03-15 Methodes permettant de diagnostiquer du cancer colo-rectal, compositions, et methodes permettant de detecter des modulateurs du cancer colo-rectal

Country Status (6)

Country Link
EP (1) EP1163524A2 (fr)
JP (1) JP2004510951A (fr)
AU (1) AU3755300A (fr)
CA (1) CA2369319A1 (fr)
MX (1) MXPA01009369A (fr)
WO (1) WO2000055633A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981220A (en) 1996-03-27 1999-11-09 Human Genome Sciences, Inc. Epidermal differentiation factor
EP1005545A1 (fr) 1997-01-16 2000-06-07 Human Genome Sciences Matrice-1 extracellulaire humaine
CA2341142A1 (fr) 1998-09-02 2000-03-09 Diadexus Llc Nouveau procede de diagnostic, de surveillance, de classification par stades, d'imagerie et de traitement de divers cancers
WO2001070798A2 (fr) * 2000-03-16 2001-09-27 K.U. Leuven Research & Development Nusap, nouveau gene codant une proteine nucleaire de specificite tissulaire utile en tant qu'outil de diagnostic et agent therapeutique
US20030077568A1 (en) * 2000-09-15 2003-04-24 Gish Kurt C. Methods of diagnosis of colorectal cancer, compositions and methods of screening for colorectal cancer modulators
US20050272120A1 (en) 2001-06-20 2005-12-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
MXPA03011985A (es) 2001-06-20 2004-03-26 Genentech Inc Composiciones y metodos para el diagnostico y tratamiento de tumores.
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
WO2003021229A2 (fr) * 2001-09-05 2003-03-13 The Brigham And Women's Hospital, Inc. Tests diagnostiques et pronostiques
US7429450B2 (en) * 2001-11-15 2008-09-30 The Regents Of The University Of Michigan HIP1 cancer markers
US7473526B2 (en) 2002-03-29 2009-01-06 Veridex, Llc Breast cancer prognostic portfolio
US7348142B2 (en) 2002-03-29 2008-03-25 Veridex, Lcc Cancer diagnostic panel
AU2003227861A1 (en) * 2002-04-11 2003-10-27 Oxford Glycosciences (Uk) Ltd Protein involved in cancer
US7252976B2 (en) 2002-08-28 2007-08-07 Board Of Regents The University Of Texas System Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
WO2004066941A2 (fr) * 2003-01-24 2004-08-12 Bayer Pharmaceuticals Corporation Profils d'expression destines au cancer du colon et procedes d'utilisation
US20070117164A1 (en) 2003-04-08 2007-05-24 Raskov Hans H Method for detection of colorectal cancer in human samples
EP1652923B1 (fr) 2003-08-08 2011-10-12 Perseus Proteomics Inc. Gene surexprime dans le cancer
NZ544432A (en) * 2005-12-23 2009-07-31 Pacific Edge Biotechnology Ltd Prognosis prediction for colorectal cancer using a prognositc signature comprising markers ME2 and FAS
US8450057B2 (en) 2006-08-14 2013-05-28 The Brigham And Women's Hospital, Inc. Diagnostic tests using gene expression ratios

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2104964A1 (fr) * 1991-02-28 1992-08-29 Ruth Sager Diagnostic et traitement du cancer
US6455678B1 (en) * 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
AU5723996A (en) * 1996-05-03 1997-11-26 Erasmus University Human rad
US5874235A (en) * 1997-07-18 1999-02-23 The Johns Hopkins University Screening assays for cancer chemopreventative agents

Also Published As

Publication number Publication date
MXPA01009369A (es) 2003-06-06
WO2000055633A2 (fr) 2000-09-21
WO2000055633A9 (fr) 2001-11-22
EP1163524A2 (fr) 2001-12-19
AU3755300A (en) 2000-10-04
WO2000055633A3 (fr) 2001-02-22
JP2004510951A (ja) 2004-04-08

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Legal Events

Date Code Title Description
FZDE Discontinued