EP1121598A4 - Detection de pleiotrophine - Google Patents

Detection de pleiotrophine

Info

Publication number
EP1121598A4
EP1121598A4 EP99951799A EP99951799A EP1121598A4 EP 1121598 A4 EP1121598 A4 EP 1121598A4 EP 99951799 A EP99951799 A EP 99951799A EP 99951799 A EP99951799 A EP 99951799A EP 1121598 A4 EP1121598 A4 EP 1121598A4
Authority
EP
European Patent Office
Prior art keywords
pleiotrophin
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99951799A
Other languages
German (de)
English (en)
Other versions
EP1121598A1 (fr
Inventor
Anton Wellstein
Boussad Souttou
Daniel Raulai
Marc Vigny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgetown University filed Critical Georgetown University
Publication of EP1121598A1 publication Critical patent/EP1121598A1/fr
Publication of EP1121598A4 publication Critical patent/EP1121598A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99951799A 1998-10-06 1999-10-06 Detection de pleiotrophine Withdrawn EP1121598A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10319798P 1998-10-06 1998-10-06
US103197P 1998-10-06
PCT/US1999/023220 WO2000020869A1 (fr) 1998-10-06 1999-10-06 Detection de pleiotrophine

Publications (2)

Publication Number Publication Date
EP1121598A1 EP1121598A1 (fr) 2001-08-08
EP1121598A4 true EP1121598A4 (fr) 2002-01-30

Family

ID=22293896

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99951799A Withdrawn EP1121598A4 (fr) 1998-10-06 1999-10-06 Detection de pleiotrophine

Country Status (4)

Country Link
EP (1) EP1121598A4 (fr)
JP (1) JP2002526777A (fr)
CA (1) CA2346406C (fr)
WO (1) WO2000020869A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60141518D1 (de) 2000-06-14 2010-04-22 Univ Georgetown Pleiotrophin wachstumfaktor rezeptor alk zur behandlung von proliferativen, gefässer- und neurologischen erkrankungen
EP1343885A2 (fr) * 2000-09-05 2003-09-17 Incyte Genomics, Inc. Molecules pour detection de maladie et traitement
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
US7888485B2 (en) 2003-03-26 2011-02-15 Georgetown University Anti-pleiotrophin antibodies and methods of use thereof
WO2005014022A1 (fr) * 2003-07-16 2005-02-17 Develogen Aktiengesellschaft Utilisation de pleitrophine pour prevenir et traiter des maladies pancreatiques et / ou l'obesite et / ou le syndrome metabolique
CA2579764A1 (fr) 2004-08-10 2006-02-23 Institute For Multiple Myeloma And Bone Cancer Research Procedes pour reguler la differenciation et traiter le myelome multiple
US20150329912A1 (en) * 2013-01-13 2015-11-19 Emory University Biomarkers in cancer, methods, and systems related thereto
PT110722B (pt) * 2018-05-03 2021-08-17 Instituto De Patologia E Imunologia Molecular Da Univ Do Porto Ipatimup Uso de anticorpos para o antigénio thomsen-friedenreich num método e estojo para avaliação de instabilidade de microsatelites
CN114112584B (zh) * 2021-11-19 2023-07-18 西安近代化学研究所 一种用于确定高固含量发射药熟化温度的制样工具包及使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10506003A (ja) * 1994-07-18 1998-06-16 ジョージタウン ユニバーシティー プレイオトロフィンのアンチセンスオリゴヌクレオチド
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, MITSIADIS THIMIOS A ET AL: "Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis.", XP002184322, Database accession no. PREV199598168700 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, BRIGSTOCK D R ET AL: "Pig uterine luminal fluid contains the developmentally regulated neurotrophic factor, pleiotrophin.", XP002184321, Database accession no. PREV199698645742 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; March 1998 (1998-03-01), DREYFUS JEANNE ET AL: "HB-GAM/pleiotrophin: Localization of mRNA and protein in the chicken developing leg.", XP002184320, Database accession no. PREV199800208351 *
DEVELOPMENT (CAMBRIDGE), vol. 121, no. 1, 1995, pages 37 - 51, ISSN: 0950-1991 *
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, vol. 42, no. 2, March 1998 (1998-03-01), pages 189 - 198, ISSN: 0214-6282 *
JOURNAL OF ENDOCRINOLOGY, vol. 148, no. 1, 1996, pages 103 - 111, ISSN: 0022-0795 *
See also references of WO0020869A1 *
ZHANG N ET AL: "Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors", CURRENT OPINION IN HEMATOLOGY, RAPID SCIENCE PUBLISHERS, PHILADELPHIA, PA, US, vol. 6, no. 1, January 1999 (1999-01-01), pages 44 - 50, XP002122375, ISSN: 1065-6251 *

Also Published As

Publication number Publication date
WO2000020869A1 (fr) 2000-04-13
CA2346406C (fr) 2009-02-17
EP1121598A1 (fr) 2001-08-08
JP2002526777A (ja) 2002-08-20
CA2346406A1 (fr) 2000-04-13

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