EP1121598A4 - Nachweis von pleiotrophin - Google Patents

Nachweis von pleiotrophin

Info

Publication number
EP1121598A4
EP1121598A4 EP99951799A EP99951799A EP1121598A4 EP 1121598 A4 EP1121598 A4 EP 1121598A4 EP 99951799 A EP99951799 A EP 99951799A EP 99951799 A EP99951799 A EP 99951799A EP 1121598 A4 EP1121598 A4 EP 1121598A4
Authority
EP
European Patent Office
Prior art keywords
pleiotrophin
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99951799A
Other languages
English (en)
French (fr)
Other versions
EP1121598A1 (de
Inventor
Anton Wellstein
Boussad Souttou
Daniel Raulai
Marc Vigny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgetown University filed Critical Georgetown University
Publication of EP1121598A1 publication Critical patent/EP1121598A1/de
Publication of EP1121598A4 publication Critical patent/EP1121598A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99951799A 1998-10-06 1999-10-06 Nachweis von pleiotrophin Withdrawn EP1121598A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10319798P 1998-10-06 1998-10-06
US103197P 1998-10-06
PCT/US1999/023220 WO2000020869A1 (en) 1998-10-06 1999-10-06 Detection of pleiotrophin

Publications (2)

Publication Number Publication Date
EP1121598A1 EP1121598A1 (de) 2001-08-08
EP1121598A4 true EP1121598A4 (de) 2002-01-30

Family

ID=22293896

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99951799A Withdrawn EP1121598A4 (de) 1998-10-06 1999-10-06 Nachweis von pleiotrophin

Country Status (4)

Country Link
EP (1) EP1121598A4 (de)
JP (1) JP2002526777A (de)
CA (1) CA2346406C (de)
WO (1) WO2000020869A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7528109B2 (en) 2000-06-14 2009-05-05 Georgetown University Pleiotrophin growth factor receptor for the treatment of proliferative, vascular and neurological disorders
WO2002040715A2 (en) * 2000-09-05 2002-05-23 Incyte Genomics, Inc. Molecules for disease detection and treatment
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
US7888485B2 (en) 2003-03-26 2011-02-15 Georgetown University Anti-pleiotrophin antibodies and methods of use thereof
EP1644027B1 (de) * 2003-07-16 2014-04-09 Evotec International GmbH Verwendung von pleiotrophin zur behandlung von bauchspeicheldrüsenkrankheiten, fettsucht und metabolischem syndrom
CA2579764A1 (en) 2004-08-10 2006-02-23 Institute For Multiple Myeloma And Bone Cancer Research Methods of regulating differentiation and treating of multiple myeloma
US20150329912A1 (en) * 2013-01-13 2015-11-19 Emory University Biomarkers in cancer, methods, and systems related thereto
PT110722B (pt) * 2018-05-03 2021-08-17 Instituto De Patologia E Imunologia Molecular Da Univ Do Porto Ipatimup Uso de anticorpos para o antigénio thomsen-friedenreich num método e estojo para avaliação de instabilidade de microsatelites
CN114112584B (zh) * 2021-11-19 2023-07-18 西安近代化学研究所 一种用于确定高固含量发射药熟化温度的制样工具包及使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10506003A (ja) * 1994-07-18 1998-06-16 ジョージタウン ユニバーシティー プレイオトロフィンのアンチセンスオリゴヌクレオチド
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, MITSIADIS THIMIOS A ET AL: "Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis.", XP002184322, Database accession no. PREV199598168700 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, BRIGSTOCK D R ET AL: "Pig uterine luminal fluid contains the developmentally regulated neurotrophic factor, pleiotrophin.", XP002184321, Database accession no. PREV199698645742 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; March 1998 (1998-03-01), DREYFUS JEANNE ET AL: "HB-GAM/pleiotrophin: Localization of mRNA and protein in the chicken developing leg.", XP002184320, Database accession no. PREV199800208351 *
DEVELOPMENT (CAMBRIDGE), vol. 121, no. 1, 1995, pages 37 - 51, ISSN: 0950-1991 *
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, vol. 42, no. 2, March 1998 (1998-03-01), pages 189 - 198, ISSN: 0214-6282 *
JOURNAL OF ENDOCRINOLOGY, vol. 148, no. 1, 1996, pages 103 - 111, ISSN: 0022-0795 *
See also references of WO0020869A1 *
ZHANG N ET AL: "Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors", CURRENT OPINION IN HEMATOLOGY, RAPID SCIENCE PUBLISHERS, PHILADELPHIA, PA, US, vol. 6, no. 1, January 1999 (1999-01-01), pages 44 - 50, XP002122375, ISSN: 1065-6251 *

Also Published As

Publication number Publication date
JP2002526777A (ja) 2002-08-20
CA2346406A1 (en) 2000-04-13
EP1121598A1 (de) 2001-08-08
CA2346406C (en) 2009-02-17
WO2000020869A1 (en) 2000-04-13

Similar Documents

Publication Publication Date Title
EP1062365A4 (de) Nachweis von fermentation-verwandten mikroorganismen
EP1102535A4 (de) Verbindungen und verfahren
GB9801286D0 (en) Sensor
GB0111769D0 (en) Differential VGMR sensor
AU137416S (en) Sensor
EP1121598A4 (de) Nachweis von pleiotrophin
EP0927353A4 (de) Nachweis von mikroorganismen
GB9913856D0 (en) Detection of microorganisms
GB9923564D0 (en) Detection of objects
GB9823186D0 (en) Detection system
GB2332529B (en) Detection
GB9711941D0 (en) Detection of pathogens
GB2343104B (en) Carrying aid
GB9811934D0 (en) Leak detection
GB9814600D0 (en) Detecting microorganisms
GB9802503D0 (en) Sensor
GB9806759D0 (en) Detection of micro-organisms
GB9801668D0 (en) Detection of organisms
GB9900307D0 (en) Detecting concealead objects
GB9714594D0 (en) Detection of microorganisms
GB9909786D0 (en) Detection of microorganisms
GB9905711D0 (en) Rapid out of level detection
GB9807881D0 (en) Detection of proteins
GB9705953D0 (en) Detection
GB9705853D0 (en) Detection

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010426

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7G 01N 33/574 A, 7G 01N 33/74 B, 7G 01N 33/50 B

A4 Supplementary search report drawn up and despatched

Effective date: 20011217

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20050517

17Q First examination report despatched

Effective date: 20050517

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080805