EP1119313A2 - Ameliorations apportees a un appareil de retention - Google Patents

Ameliorations apportees a un appareil de retention

Info

Publication number
EP1119313A2
EP1119313A2 EP99954499A EP99954499A EP1119313A2 EP 1119313 A2 EP1119313 A2 EP 1119313A2 EP 99954499 A EP99954499 A EP 99954499A EP 99954499 A EP99954499 A EP 99954499A EP 1119313 A2 EP1119313 A2 EP 1119313A2
Authority
EP
European Patent Office
Prior art keywords
animal
delivery device
substance delivery
retention
restraining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99954499A
Other languages
German (de)
English (en)
Inventor
Brian Cornish
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advanced Animal Technology Ltd
Original Assignee
Advanced Animal Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Animal Technology Ltd filed Critical Advanced Animal Technology Ltd
Publication of EP1119313A2 publication Critical patent/EP1119313A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals

Definitions

  • This invention relates to improvements in and relating to retention apparatus.
  • the retention apparatus will be most commonly used to retain a substance delivery device in a passage or body cavity of an animal.
  • the retention apparatus will be most commonly used in situations for retaining a substance delivery device in a body cavity that can be readily accessed, such as the " vagina, uterus, rectum, and so forth.
  • the retention apparatus is designed to maintain the substance delivery device in said cavity for predetermined periods to enable substances in the delivery device to be delivered into the animal in a manner (controlled or otherwise) over the required period of time.
  • Such substance delivery devices may be used to control the release of substances into the animal for controlling parasites, release of nutritional supplements, for vaccines, for controlling reproduction and/or growth and so forth as part of a programme involving chemical and/or hormonal intervention.
  • a range of retention apparata is available in the prior art for use in retaining associated apparatus in or on an animal for a required time period.
  • the retention apparatus may be included on or be attachable to the apparatus.
  • Retention apparata for retaining a device within a passage or body cavity of an animal may be fully (along with the device) or partially inserted into the animal.
  • the retention apparatus may be compressible. Once inserted, the retention apparatus typically resumes its uncompressed configuration thereby retaining the device to which it is attached within the animal's body cavity.
  • Such retention apparata may be an integral part of the device as with compressible helical coils, or the devices may include multiple lobes or arms affixed to a device.
  • the latter types of retention apparata rely on the ability to fold the lobes or arms onto each other to facilitate insertion of the device into the body cavity of the animal.
  • the lobes or arms may be flexed or hinged to a position where they are substantially in line with the device to which they are attached for easy insertion of the device into the animal's body cavity. Once inserted the compressed coil, lobes or arms spring open to retain the device inside the animal's body cavity.
  • problems exist with the use of such retention apparata. For example, apparatus that expands once inserted into the body cavity of an animal can a) cause irritation to the walls of the cavity and discomfort to the animal.
  • retention apparata allow retention of the device within the animal's body cavity
  • movement of the device within the cavity is also typically permitted. This movement can lead to internal irritation of the cavity (and cervix if the cavity is the vagina of the animal)and cause discomfort to the animal, b) impact detrimentally on the flow of the animal's internal body secretions, c) be difficult to extract from the animal's body cavity once the functional utility of the device to which they are attached has been exhausted, and d) be problematic to insert into the animal's body cavity in the first instance due to the nature of the material from which the retention apparatus are made and therefore e) require a separate applicator to facilitate insertion of the device and the retention apparatus into the animal's body cavity, and. f) often be suitable only for use in small body cavities
  • the retention apparatus may itself be impregnated with, or contain, the substances required to be delivered into the animal's body cavity.
  • secretion of the substance into the body cavity can effectively reduce the surface area of the retention apparatus and in turn reduce the ability of the retention apparatus to retain the substance delivery device in the animal's body cavity.
  • muscular contractions of the walls of the animal's body cavity may force the device and its retention apparatus out of the animal's body cavity before complete delivery of the substance(s) has been achieved. Therefore, the effectiveness of the substance delivery device may be severely limited.
  • (d) is suitable for use with devices to be inserted into body cavities such as the vagina, uterus and rectum (principally); and (e) can be used without causing undue physical discomfort to the animal; and
  • retention apparatus capable of retaining a substance delivery device within a body cavity of an animal into which the substance delivery device is inserted, the retention apparatus including positioning apparatus capable of maintaining the substance delivery device in a preferred position within the body cavity of an animal, and restraining apparatus capable of hindering unwanted removal of the positioning apparatus and the substance delivery device from the animal' s body cavity, characterised in that at least a portion of the restraining apparatus is attached in a preferred location on the external surface of the animal's body via attachment means.
  • retention apparatus substantially as described above wherein at least a portion of the positioning apparatus is inserted into the animal.
  • retention apparatus substantially as described above wherein the positioning apparatus also includes engaging apparatus capable of engaging with either or both a portion of the restraining apparatus and the substance delivery device.
  • the restraining apparatus is comprised of resilient material capable of being stretched to effect the required tension to maintain the positioning apparatus and the substance delivery device substantially within the animal's body.
  • retention apparatus substantially described above wherein the restraining apparatus includes a substantially elongate portion and a substantially expanded portion.
  • the attachment apparatus is a contact adhesive capable of being applied to either one or both of the expanded portion of the restraining apparatus and the external surface of the animal's body.
  • positioning apparatus shall mean and refer to any apparatus that is capable of positioning the substance delivery device in a preferred position within an animal's body cavity.
  • tail rod For ease of reference the positioning apparatus shall now be referred to as a tail rod. However, it should be appreciated that use of this term is not to be seen as limiting.
  • restraining apparatus in this specification shall mean (unless otherwise stated) any apparatus capable of maintaining at least the tail rod in the required position within the animal's body cavity whilst specifically hindering the ability of the tail rod and the substance delivery device attached thereto to work out of the animal's body cavity when the animal is engaged in normal daily activities and/or bodily functions.
  • the animal's activities include but are not limited to normal walking or running movements, mounting of the animal by another animal, defecation, urination, muscular activity within the animal's body cavity into which the substance delivery device has been inserted, and the production by the animal of secretions such as mucus that could operate to lubricate the entry to the animal's cavity and facilitate expulsion of the substance delivery device and the tail rod from the cavity.
  • attachment means in the specification shall mean unless otherwise stated, any apparatus or means of attachment capable of fastening, affixing or joining the restraining apparatus on to or around the external surface of the animal's body.
  • means of attachment shall now be referred to as an adhesive.
  • this term is not intended to limit the use of any other suitable means of attachment or apparatus capable of performing the required function as stated above.
  • the substance delivery device referred to in the specification substantially includes a body (or sheath) capable of substantially enclosing all of the components of the substance delivery device.
  • the applicant has described a preferred embodiment of the substance delivery device in New Zealand Patent Specification No. 304150. However, any suitable substance delivery device may be used with the present invention.
  • the substance delivery device preferably is used to deliver at least one therapeutic agent into the animal.
  • the therapeutic agent can include either or both one or more chemicals and hormonal substances.
  • the substance delivery device may be used to deliver nutrients, vaccines, breeding hormones, growth hormones, anti-parasitic treatments and so forth. Administration of the agents being achieved by insertion of the substance delivery device into an animal's body cavity, and release of the agents therefrom and into the animal.
  • the tail rod is a substantially solid and rigid rod.
  • a solid rod is preferred to ensure the rod is sufficiently strong enough to withstand wear and tear, particularly when used in the larger domestic animals such as horses and cows.
  • hollow rods may also be suitable.
  • the tail rod is a single unit.
  • the tail rod may be comprised of two or more sections attached to each other to obtain the required length, as needed for the particular animal with which the positioning apparatus is used.
  • the tail rod is preferably rod shaped to provide a smooth outer surface, free of angles or corners that may otherwise cause physical discomfort to the animal or result in irritation of the linings of the animal's body cavity or passages by such sharp edges.
  • the round rod shape contributes to the ease of insertion of the tail rod into the animal's cavity/passage.
  • the dimensions of the tail rod are specific to the species of animal with which the tail rod (and the substance delivery device attached to it) is used.
  • the dimensions of the tail rod for use with animals within the same species due to the age, sex and/or breeding status of the animal into which the tail rod and the substance delivery device are to be inserted.
  • the dimensions of the tail rod will be specifically (and therefore varyingly) designed for older dairy cows, first mated heifers, beef cows and early post-partem dairy cows and so forth.
  • the vaginal canal can differ depending on age of the animals within the same species, and also differs between species.
  • the tail rod may be used with a substance delivery device for insertion into different body cavities (such as the rectum), again the length of the tail rod will understandably vary.
  • the length of the tail rod is critical for ensuring the device is inserted past the pelvic bone of the animal.
  • trials with the retention apparatus having a tail rod inserted at 100mm into the vaginal cavity of mature cows resulted in rotation and expulsion of the device.
  • having the tail rod inserted 150mm into the vaginal cavity ensured greater retention of both the tail rod and the substance delivery device within the animal.
  • the tail rod is made from substantially rigid material.
  • the applicant has found that use of some polyurethane PNC materials provide too much flexibility to the rod, enabling the rod to be worked out of the animal's body cavity and leading to expulsion of the entire system by the animal.
  • materials used for the tail rods (and the substance delivery device body) should pose no physiological danger to, cause no allergic reactions in and cause minimal discomfort to the animal.
  • the tail rod is preferably configured to include an elongate straight portion.
  • the substantially elongate straight portion is designed to facilitate insertion of the tail rod into the animal's body cavity without causing undue discomfort to the animal.
  • an undulating elongate portion may be preferred for use in some cavities and/or passages, or with some animals to ensure optimum retention inside the animal.
  • the length of the elongate portion is such that it ensures and the attached substance delivery device is also inserted into the animal's body cavity to the required depth.
  • the tail rod also includes a substantially angled portion at one of its distal ends.
  • This angled portion may operate as a stop to complete insertion of the rod within the animal's cavity/passage.
  • the angled portion operating as a stop by pressing against the outside of the animal adjacent to the cavity /passage entrance.
  • the length of the angled portion may vary depending on the overall anatomy of the animal with which the positioning apparatus is used.
  • this angled portion of the rod may vary in configuration when it is used as a stop, to ensure better co-operation of the surface of the angled portion against the animal.
  • the overall configuration of the tail rod facilitates retention of it and the attached substance delivery device within in the animal's body cavity.
  • the opposite distal end (opposite in the angled portion) of the tail rod is substantially straight.
  • the substance delivery device may be fixedly or removably attached to this straight, distal, end of the substantially elongate straight portion.
  • the tail rod is fixed to the substance delivery device via a one-way engaging system, such as a bayonet system or press fitting system that operates to fix the tail rod to the substance delivery device in a non-removable manner.
  • the substance delivery device and the tail rod may be moulded in one piece to obviate problems of the substance delivery device becoming detached from the tail rod.
  • the substance delivery device may be removably attached to the tail rod to enable the tail rod to be used repeatedly, simply by replacing an expended substance delivery device with a new one.
  • Such removable attachment of the substance delivery device to the tail rod may be effected through engaging a complementarily configured section at the end of the substantially elongate portion of the tail rod with a corresponding section on the substance delivery device.
  • Such configuration could include a threaded, bayonet or other suitable system.
  • a portion of the substance delivery device may simply be inserted into the end of the tail rod and pinned in position.
  • insertion of a locking pin into an appropriately located aperture on the external surface of the tail rod which can be aligned with a similarly located aperture on the inserted portion of the substance delivery device.
  • any suitable arrangement for attaching the tail rod to the substance delivery device may be employed with this invention as required.
  • the substantially angled distal end of the tail rod is preferably configured to receive a portion of the restraining apparatus.
  • the restraining apparatus shall now be referred to as a tail.
  • the substantially angled portion includes a series of barbs integrally moulded into the tail rod. These projecting barbs are capable of being received into, or are capable of receiving, a complementarily configured portion of the tail.
  • the arrangement is designed to be a quick fit system to enable easy attachment and removal of the tail onto and from the tail rod.
  • any suitable means of attaching the tail to the substantially angled portion of the tail rod may be used with this invention.
  • the tail rod and the tail be a single structure ready for attachment to the substance delivery device.
  • the entire combination of the tail, tail rod and substance delivery device may be moulded in one piece for devices that are to be thrown away after use.
  • individual tails, tail rods and substance delivery devices may be preferred where reuse of the individual sections is required or desired.
  • the tail includes a substantially elongate portion and a substantially expanded portion.
  • the expanded tail portion is located towards one distal end of the elongate portion of the tail, whilst the other distal end the elongate portion is configured to attach (either fixedly or removable) to the angled portion of the tail rod.
  • substantially elongate portion shall be referred to as a strap and the substantially expanded portion shall be referred to as a patch.
  • the use of either of these terms is not intended to limit the scope of the specification.
  • the length of the strap is dictated by the species of animal with which the retention apparatus is being used. In addition, the length will also be dictated by the age and sex of the particular animal.
  • the width of the strap is also dictated by a number of factors including the ability of the strap to perform the required function in relation to the retention apparatus without interfering with the normal bodily functions of the animal, or causing undue discomfort to the animal.
  • the tail is required to be made of substantially flexible material. The material is preferably soft/supple enough to be able to be moulded to conform to the external shape of the animal against which the strap rests again without interfering with the bodily functions of the animal and without causing unnecessary discomfort to the animal.
  • the restraining apparatus is also made of resilient material capable of being stretched to effect the tension required to maintain the tail rod and substance delivery device within the animal's body cavity whilst also being firmly attached at a suitable location to the exterior surface of the animal's body.
  • the tail is made of a rubber material of a particular formulation to provide the required resilience, flexibility and durability, without causing any adverse physiological reactions in (such as allergic reactions) or physical discomfort to the animal with which it is used.
  • any suitable material may be adapted for use with the invention.
  • early prototypes included plastic and/or metal wires capable of being bent to conform to and be moulded against the animal's body.
  • wires whilst capable of being used, have limitations in terms of their resilience.
  • the tail is made from layers of the preferred rubber material that is laminated.
  • the strap includes a greater number of laminated layers than the patch. Multiple layers can increase the strength of and contribute to the required resilience of the strap.
  • the patch is preferably thinner to enable the patch to be flexible enough to be secured to the animal's external surface by the attachment apparatus.
  • the tail is injection moulded using the specific rubber material to produce a tail in which the stem is substantially thicker than the patch (which essentially looks like a paddle), but where the entire tail is produced in one procedure.
  • the tail may be stamped/cut from sheet material having the required properties and thickness in the strap and patch areas.
  • the resilience of the material is also such that it is capable of being stretched to effect the required tension when the strap is attached to the animal.
  • the strap is flexible enough to enable the strap of the tail to be moulded to conform to the shape of the animal's external body surface without interfering with the animal's normal bodily " functions.
  • the tail is moulded to conform to the shape of the cow without interfering with the function of the cow's tail, or with the animal's defecation or urination.
  • the tail is able to fit closely to the perineum to prevent faecal matter from gaining ingress to the vaginal cavity.
  • the tail is required to be made of substantially resilient and flexible material, it is preferable that the material demonstrate a firm elasticity to prevent over-stretching of the tail. Over-stretching of the tail could enable the tail rod to rotate and be expelled from the animal's body cavity.
  • the patch is required to be of a sufficient surface area to ensure secure attachment of the tail to the animal's body.
  • the patch of the tail is substantially circular.
  • the applicant has experimented with a range of shapes for the patch portion of the tail, and whilst other shapes may be used, the circular patch is preferred. This overall configuration of the patch has been found to be critical to the success of attachment of the patch to the external surface of the animal's body.
  • the dimensions of the strap and/or patch may also be adjustable to enable the tail to be used on animals of different ages, sexes and so forth.
  • the tail used for cows may be different to that used for heifers or young stock, and so forth. Therefore, to accommodate the differing requirements, the patch and strap may be two separate portions that may be joined together as required.
  • Such an embodiment may also include adjustment apparatus to facilitate adjustment of the tail for use with a particular animal.
  • one-piece systems may also include such adjustment apparatus.
  • the material of the tail is required to be sufficiently strong to obviate against the tail breaking/snapping.
  • the substantially thicker strap contributes to providing the required strength.
  • the patch is preferably attached in the region of the animal's tail but to one side of the animal's backbone.
  • the point of attachment is located between the backbone and the pin bone (ischium) of an animal, such as a cow.
  • This positioning enables the tail to be attached to the animal's external surface whilst providing sufficient tension to maintain the tail rod in the body cavity without the retention apparatus interfering with other bodily functions of the animal such as urination and so forth (depending upon the cavity into which the substance delivery device is inserted).
  • the patch is attached to the external surface of the animal's body by the means of attachment.
  • the means of attachment is an adhesive.
  • the means of attachment is a contact adhesive that is fast curing and capable of being used on animals with minimal (if any) detrimental effects or discomfort. Accordingly, the contact adhesive is anti-allergenic, physiologically safe and so forth.
  • the adhesive is one that is preferably capable of attaching the patch to the animal's external surface irrespective of the animal's hair or fur type, or length.
  • attachment of the patch to the animal's external surface may be affected by external conditions, such as material on which the animal beds down, or rolls in. Where the ground or bedding material is dusty and/or sandy, the animal's body may need to be shaved in the region where the patch is to be attached.
  • the area may also be cleaned with a suitable fluid (such as a solvent, or a burst of air, and so forth), to further reduce the amount of material on the animal's skin that may affect the ability of the patch to adhere the thereto.
  • a suitable fluid such as a solvent, or a burst of air, and so forth
  • the applicant has trialled a range of adhesives such as MULTIGRASSTM (supplied by Bostik) and KAMARTM with varying degrees of success.
  • the preferred adhesive is adapted to meet the applicant's objectives which are to use an adhesive compatible with both the animal and the preferred material used for the patch, whilst also providing a very fast cure.
  • One of the advantages of using the preferred contact adhesive in the attachment of the tail to the external surface of the animal is that the substance delivery device can be inserted into the animal's body cavity and the retention apparatus secured in place with minimal time and effort but with maximum retention of the substance delivery device in the animal's body cavity for the period required to complete the program of treatment of the animal with the appropriate therapeutic agent.
  • the application of the adhesive to the patch and/or the animal may vary however, depending upon the type and length of the animal's hair or fur. In any situation a successful patch/animal bond is essential.
  • the adhesive may be applied to the animal only, the patch only, the patch and the animal and so forth.
  • the patch is temporarily pressed on to the attachment area, removed, left for a short period and then re- applied to the attachment area to enable the adhesive to bond.
  • the adhesive may be pre-applied to the patch during manufacture of the retention apparatus.
  • the adhesive may then be covered by a removable material to prevent the patch sticking to objects before required. At the time the patch is to be applied to the animal the material is peeled from the surface of the patch to expose the adhesive, ready of use.
  • the patch may be secured via other means.
  • contact tapes bubble patches containing adhesive that is released when the bubbles are burst (on contact with the animal, or when pressure is applied), and so forth may be used.
  • the present invention has been developed specifically for retaining a substance delivery device in the body cavity of an animal by employing restraining apparatus capable of being attached between the back bone and the ischium (pin bone) of a domestic animal. Trials on cows suggest the invention will be equally effective in all cow types. This concept has been developed to remedy observed deficiencies in other retention systems for such substance delivery devices.
  • plugs of mucus may also be found following the removal of the device from (for example) the vaginal cavity.
  • mucus production is due to the interaction of the villi with the sensitive vaginal mucosa and from irritation of the cervix by the front of the device.
  • villi systems whilst retaining the device intravaginally, nevertheless enables the device to move backwards and forward within the vagina.
  • the present retention system is designed to reduce mucus production, as it is less invasive and provides less opportunity for the device to contact the cervix and therefore reduces interference of the cervix by the device.
  • the depth of insertion of the tail rod, the location of the patch on the animal, the patch/animal bond, and the tightness of the tail strap are all important factors, as is minimal trauma to the animal at any stage during the treatment programme (when the substance delivery device is intra animal).
  • Figure 1 is a diagrammatic side view of the restraining apparatus in accordance of one preferred embodiment of the present invention
  • Figure 2a is a diagrammatic plan view of the restraining apparatus in accordance with one preferred embodiment of the present invention
  • Figure 2b is a diagrammatic cross-sectional view through the strap of the restraining apparatus in accordance with one preferred embodiment of the present invention
  • Figure 3a is a diagrammatic side view of the restraining apparatus in accordance with another preferred embodiment of the present invention
  • Figure 3b is a diagrammatic cross sectional view through the distal end of the restraining apparatus configured to receive or be attached to the positioning apparatus of the retention apparatus in accordance with one preferred embodiment of the present invention
  • Figures 4. 5 are diagrammatic bottom and top plan views respectively of the restraining apparatus in accordance with another preffered embodiment of the present invention
  • Figures 6a. 6b are diagrammatic side views of the positioning apparatus of the retention apparatus in accordance with one preferred embodiment of the present invention.
  • Figure 6c is a diagrammatic top plan view of the positioning apparatus in accordance with one preferred embodiment of the present invention.
  • Figures 6d. 6e are diagrammatic representations of the angled distal portions of the positioning apparatus, configured to engage with the substance delivery device and the restraining apparatus, respectively, in accordance with one preferred embodiment of the present invention
  • Fi ure 7 is a diagrammatic representation of an early prototype of the retention apparatus attached to a substance delivery device in accordance with another embodiment of the present invention
  • Figure 7b is a diagrammatic representation of a preferred embodiment of the retention apparatus attached to a substance delivery device.
  • retention apparatus generally indicated by arrow 1 , as shown in Figures 1 through 7 for retaining a substance delivery device (generally indicated by arrow 2) within a body cavity of an animal (not shown) into which the substance delivery device (2) is inserted.
  • the retention apparatus (1) includes positioning apparatus, generally indicated by arrow 3.
  • the positioning apparatus (3) is capable of maintaining the substance delivery device (2) in a preferred position within the body cavity of the animal.
  • the retention apparatus (1) also includes restraining apparatus, generally indicated by arrow 4, for hindering removal of the positioning apparatus (3) and the substance delivery device (2) from the animal's body cavity.
  • the retention apparatus (1) also allows for a means of attachment, (generally indicated by arrow 5) for attaching a portion of the restraining apparatus (4) in a preferred position on the external surface of the animal's body.
  • the substance delivery device (2) is configured to be inserted into an animal's body cavity to release therapeutic agent(s) into the animal, for a pre-determined period.
  • the substance delivery device (2) is represented in Figures 6c and 7. However, it should be appreciated that the structural configuration of the substance delivery device (2) can vary.
  • the substance delivery device (2) is substantially integrally attached to the positioning apparatus or tail rod (3).
  • the substance delivery device (2) can be adapted such that the tail rod (3) may be fixedly or removably attached to the substance delivery device (2).
  • the tail rod (3) is appropriately dimensioned in terms of width and length to enable the substance delivery device (2) to be inserted into the animal's body cavity to a depth that prevents the tail rod (3) and the substance delivery device (2) from rotating and being expelled from the animal's body cavity during the animal's normal bodily functions (such as muscular contractions) and/or general physical activities (such as bulling in cows and so forth).
  • the tail rod (3) is a substantially circular rod with an elongate portion (6) and a substantially angled portion (7).
  • the substance deliver device (2) is attached to the appropriately configured distal end (8) of the substantially elongate portion (6) of the tail rod (3), whilst the substantially angled portion (7) is configured at (9) to receive a portion of the restraining apparatus or tail (4).
  • the tail rod illustrated is substantially circular and smooth to facilitate easy insertion of the substance delivery device (2) and the tail rod (3) into the animal's body cavity without causing undue irritation to the walls of the body cavity or the entry passage, or cause undue discomfort to the animal, during the insertion, withdrawl or retention period.
  • the tail rod (3) in Figure 7 also includes flexible joints (10) to enable the tail rod (3) to conform to the required shape to facilitate configuration of the tail rod (3) for the animal with which it is used.
  • Figure 7 representing an earlier prototype illustrates, the restraining apparatus or tail (4) comprising a wire tail (16) and a plastic tail (17), both of which are fed through the tail rod (3).
  • the tail (4) as illustrated in Figures 1-5 inclusive, are made of a substantially resilient and flexible rubber material to enable the tail (4) mould to the external surface of the animal as required to enable the tail (4) to effectively restrain the tail rod (3) and the substance delivery device (2) from being expelled from or working out of the animal's body cavity.
  • the tail (4) includes a strap (11) and a patch (12).
  • the strap (11) is substantially elongate, the length being dictated by either or both the species of animal with which it is to be used and the age of the animal.
  • the patch (12) is substantially circular and substantially thinner than the strap (11) portion of the tail (4) (as shown in Figures 1 through 5).
  • the dimensions and/or configuration of the patch (12) are critical to ensuring successful attachment of the patch (12) to the external surface of the animal's body.
  • the patch (12) is positioned towards one distal end (13) of the strap (11).
  • the opposite distal end (14) of the strap is configured at (18) to complement and be attached to the configured distal end (9) of the tail rod (3).
  • the retention apparatus (1) is either integral with the substance delivery device (2) or is attached to the substance delivery device (2) for use.
  • the substance delivery device (2), the tail rod (3) and the tail (4) may be either moulded in one piece.
  • one or more of the substance delivery device (2), the tail rod (3) and the tail (4) may be separate from or attached to, an adjacent portion depending upon the requirements of the retention apparatus (1) and the substance delivery device (2).
  • the retention apparatus (1) and the substance delivery device (2) are designed to be discarded after use, all three features may be moulded as one piece.
  • the tail rod (3) and/or the tail (4) can be re-used or interchanged, accordingly, they are preferably configured to be capable of inter-connection to the other apparata.
  • Figures 1 to 5 illustrate embodiments of the tail (4).
  • Figures 1 and 3b show the distal end (14) of the strap where it is configured at (18) to receive an appropriately configured portion of the tail rod (3).
  • Figure 2b further illustrates a cross-sectional view through the strap (11) having a preferred configuration.
  • the strap (11) portion of the tail (4) differs in thickness to the patch (12).
  • the means of attachment (5) in preferred embodiments is a preferred contact adhesive capable of being used with animals.
  • any suitable adhesive may be used with the retention apparatus provided it is effective at maintaining contact between the patch (12) and the external surface of the animal's body throughout the period of treatment. Treatment periods may be relatively short (up to a few days) or may be considerably longer (several weeks).
  • adhesive (5) is the preferred means of attachment, nevertheless, other embodiments of the invention may incorporate other attachment apparatus specifically designed for different species of animals where adhesive may be unsuitable.
  • Both the substance delivery device (2) and the tail rod (3) are inserted into an animal's body cavity such as the vaginal cavity, the rectal cavity and so forth into which a therapeutic agent(s) is required to be delivered.
  • the tail rod (3) is inserted to a depth where it optimally contributes to maintaining the substance delivery device (2) within the animal's body cavity.
  • the tail rod (3) may protrude only so far (or not at all) to ensure effectiveness of the tail (4) - providing the tail rod (3) does not catch on any part of the cow's anatomy (such as the tail) or is not capable of being contacted by another animal or by environmental objects that may cause movement of the tail rod (4) and the substance delivery device (2) within the animal's body cavity, or may contribute to the substance delivery device being expelled from the animal's body cavity.
  • the strap (11) of the tail (4) is stretched to create sufficient tension to enable the strap (11) to mould or conform to the shape of the body of the animal without interfering with the animal's bodily functions.
  • the strap (11) is stretched to provide sufficient tension to maintain the tail rod (3) in position whilst not impeding the function of the animal's tail, or the bodily functions of defecation or urination.
  • the strap (11) of the tail (4) is positioned to sit closely to the animal's perineum to prevent faecal matter from gaining ingress to the vaginal cavity.
  • the tail (4) holds the tail rod (3) firm and ensures the intravaginal device (2) remains securely in the vagina by ensuring appropriate tension of the strap (11) and attachment of the patch (12) to the cow's back between the back bone and the ischium (pin bone).
  • the point of attachment on the animal's external surface will depend upon the body cavity with which the substance delivery device (2) and the retention apparatus (1) are used.
  • the adhesive (5) is then applied to either or both the patch (12) and the external surface of the animal's body. After the required period of time to allow the adhesive to bond with the surface onto which it has been applied, the patch (12) is then pressed onto the glue patch on the animal's body. The patch (12) is held in position for sufficient time to ensure bonding between the patch (12) and the animal's body.
  • the dimensions and configuration of the substance delivery device (2), the tail rod (3) and the tail (4), as well as the type of attachment apparatus (5) will depend largely upon the species of animal with which the apparatus is used. The age and sex of the animal will also be factors to consider. Similarly, it may be necessary to use different materials for both the tail rod (3) and the tail (4) as required to ensure effectiveness of the retention apparatus (1) with different species of animals. Aspects of the present invention have been described by way of example only and it should be appreciated that modifications and additions may be made thereto without departing from the scope thereof as defined in the appended claims.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne des améliorations apportées à un appareil de rétention. L'appareil de rétention est utilisé afin de maintenir une administration de substance dans un passage ou une cavité corporelle d'un animal durant des périodes prédéterminées, en particulier dans une cavité d'accès facile et comprenant le vagin, l'utérus et le rectum. Une telle rétention est requise lorsqu'il est souhaitable d'administrer chez l'animal, à partir du dispositif d'administration, de manière régulée, des substances dans le cadre de programmes d'intervention chimique et/ou hormonal. Les substances administrées peuvent comprendre des agents antiparasitaires, des suppléments nutritionnels, des vaccins, des hormones, et ainsi de suite. L'appareil de rétention comprend un appareil de positionnement afin de maintenir le dispositif d'administration dans une position préférée dans la cavité de l'animal et un appareil de retenue afin d'empêcher un retrait non désiré de l'appareil de positionnement et du dispositif d'administration de substance de la cavité. L'invention est caractérisée par une partie de l'appareil de retenue attachée à un emplacement préféré sur la surface extérieure du corps de l'animal à l'aide de moyens d'attache.
EP99954499A 1998-10-05 1999-10-05 Ameliorations apportees a un appareil de retention Withdrawn EP1119313A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ33220898 1998-10-05
NZ33220898 1998-10-05
PCT/NZ1999/000167 WO2000019937A2 (fr) 1998-10-05 1999-10-05 Ameliorations apportees a un appareil de retention

Publications (1)

Publication Number Publication Date
EP1119313A2 true EP1119313A2 (fr) 2001-08-01

Family

ID=19926963

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99954499A Withdrawn EP1119313A2 (fr) 1998-10-05 1999-10-05 Ameliorations apportees a un appareil de retention

Country Status (4)

Country Link
EP (1) EP1119313A2 (fr)
AU (1) AU750746B2 (fr)
CA (1) CA2346091A1 (fr)
WO (1) WO2000019937A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR202019016494U2 (pt) * 2019-08-08 2021-02-09 Wta - Watanabe Tecnologia Aplicada Eireli - Epp Dispositivo para liberação lenta de progesterona

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1212918A (fr) * 1982-07-06 1986-10-21 James S. Cullor Crossance de cellules in vitro dans du liquide allantoidien
FR2720929B1 (fr) * 1994-06-09 1996-10-11 Gestion Engineering Et Dispositif d'insémination artificielle par gravité, notamment pour truie.
CA2216256A1 (fr) * 1995-03-23 1996-09-26 Advanced Animal Technology Limited Dispositif d'administration d'une substance
NZ304150A (en) 1995-03-23 2000-01-28 Advance Animal Technology Ltd Substance delivery device
US6669682B1 (en) * 1998-02-25 2003-12-30 Bryher Holdings Limited Veterinary delivery device and method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0019937A2 *

Also Published As

Publication number Publication date
CA2346091A1 (fr) 2000-04-13
WO2000019937A2 (fr) 2000-04-13
WO2000019937A3 (fr) 2000-08-17
AU1083500A (en) 2000-04-26
AU750746B2 (en) 2002-07-25

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