EP1112080A4 - REGULATION DE L'EXPRESSION D'ONCOGENE HER2/neu A L'AIDE DE POLYAMIDES SYNTHETIQUES - Google Patents

REGULATION DE L'EXPRESSION D'ONCOGENE HER2/neu A L'AIDE DE POLYAMIDES SYNTHETIQUES

Info

Publication number
EP1112080A4
EP1112080A4 EP19990952908 EP99952908A EP1112080A4 EP 1112080 A4 EP1112080 A4 EP 1112080A4 EP 19990952908 EP19990952908 EP 19990952908 EP 99952908 A EP99952908 A EP 99952908A EP 1112080 A4 EP1112080 A4 EP 1112080A4
Authority
EP
European Patent Office
Prior art keywords
her2
regulation
neu oncogene
synthetic polyamides
oncogene expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19990952908
Other languages
German (de)
English (en)
Other versions
EP1112080A1 (fr
Inventor
Peter B Dervan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Publication of EP1112080A1 publication Critical patent/EP1112080A1/fr
Publication of EP1112080A4 publication Critical patent/EP1112080A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP19990952908 1998-09-11 1999-09-10 REGULATION DE L'EXPRESSION D'ONCOGENE HER2/neu A L'AIDE DE POLYAMIDES SYNTHETIQUES Withdrawn EP1112080A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9990698P 1998-09-11 1998-09-11
US99906P 1998-09-11
PCT/US1999/020971 WO2000015242A1 (fr) 1998-09-11 1999-09-10 REGULATION DE L'EXPRESSION D'ONCOGENE HER2/neu A L'AIDE DE POLYAMIDES SYNTHETIQUES

Publications (2)

Publication Number Publication Date
EP1112080A1 EP1112080A1 (fr) 2001-07-04
EP1112080A4 true EP1112080A4 (fr) 2002-10-24

Family

ID=22277188

Family Applications (2)

Application Number Title Priority Date Filing Date
EP19990952908 Withdrawn EP1112080A4 (fr) 1998-09-11 1999-09-10 REGULATION DE L'EXPRESSION D'ONCOGENE HER2/neu A L'AIDE DE POLYAMIDES SYNTHETIQUES
EP99969022A Withdrawn EP1162961A2 (fr) 1998-09-11 1999-09-10 Regulation de l'expression oncongene de her2/neu par des polyamides synthetiques

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP99969022A Withdrawn EP1162961A2 (fr) 1998-09-11 1999-09-10 Regulation de l'expression oncongene de her2/neu par des polyamides synthetiques

Country Status (5)

Country Link
EP (2) EP1112080A4 (fr)
JP (2) JP2002524525A (fr)
AU (2) AU6496599A (fr)
CA (2) CA2343289A1 (fr)
WO (2) WO2000015242A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1252260C (zh) * 2000-07-21 2006-04-19 上海三维生物技术有限公司 肿瘤特异性启动子
US7122626B2 (en) 2001-04-26 2006-10-17 Genesoft Pharmceuticals, Inc. Halogen-substitued thienyl compounds
EP1470119A4 (fr) 2001-06-13 2005-10-19 Genesoft Pharmaceuticals Inc Composes benzothiophene presentant une activite anti-infectieuse
US6777425B2 (en) 2001-06-13 2004-08-17 Genesoft Pharmaceuticals, Inc. Isoquinoline compounds having antiinfective activity
US6716866B2 (en) 2001-06-13 2004-04-06 Genesoft Pharmaceuticals, Inc. Aryl-benzimidazole compounds having antiinfective activity
US20030236198A1 (en) 2001-06-13 2003-12-25 Genesoft, Inc. Antipathogenic benzamide compounds
WO2004012736A1 (fr) 2002-08-02 2004-02-12 Genesoft Pharmaceuticals, Inc. Composes biaryle a action anti-infectieuse
US7265129B2 (en) 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
WO2004052304A2 (fr) 2002-12-10 2004-06-24 Oscient Pharmaceuticals Corporation Composes antibacteriens possedant un motif (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide)
JP3792655B2 (ja) 2003-01-20 2006-07-05 日本電気株式会社 新規な癌遺伝子、該癌遺伝子由来の組換えタンパク質、およびそれらの用途
JP2006022063A (ja) * 2004-07-09 2006-01-26 Univ Nihon Ｌｏｘ−１遺伝子発現抑制剤
CA3034257A1 (fr) * 2016-08-29 2018-03-08 California Institute Of Technology Compositions et methodes de traitement du cancer de la prostate
US10723716B2 (en) 2016-12-21 2020-07-28 New York University Alpha-helix mimetics as modulators of Abeta self-assembly

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035702A1 (fr) * 1996-08-01 1998-08-20 California Institute Of Technology Inhibition de la transcription de genes par des ligands de polyamide se fixant a l'adn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035702A1 (fr) * 1996-08-01 1998-08-20 California Institute Of Technology Inhibition de la transcription de genes par des ligands de polyamide se fixant a l'adn

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO0015242A1 *
WHITE S ET AL: "RECOGNITION OF THE FOUR WATSON-CRICK BASE PAIRS IN THE DNA MINOR GROOVE BY SYNTHETIC LIGANDS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 391, no. 6666, 29 January 1998 (1998-01-29), pages 468 - 471, XP002072062, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
WO2000015209A3 (fr) 2000-05-25
JP2002524501A (ja) 2002-08-06
CA2344654A1 (fr) 2000-03-23
AU6034199A (en) 2000-04-03
CA2343289A1 (fr) 2000-03-23
AU768405B2 (en) 2003-12-11
AU6496599A (en) 2000-04-03
EP1112080A1 (fr) 2001-07-04
WO2000015242A1 (fr) 2000-03-23
JP2002524525A (ja) 2002-08-06
EP1162961A2 (fr) 2001-12-19
WO2000015209A2 (fr) 2000-03-23

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