EP1082463A4 - Durch mechanischen stress induzierte gene, deren expressionsprodukte und deren verwendung. - Google Patents
Durch mechanischen stress induzierte gene, deren expressionsprodukte und deren verwendung.Info
- Publication number
- EP1082463A4 EP1082463A4 EP99923223A EP99923223A EP1082463A4 EP 1082463 A4 EP1082463 A4 EP 1082463A4 EP 99923223 A EP99923223 A EP 99923223A EP 99923223 A EP99923223 A EP 99923223A EP 1082463 A4 EP1082463 A4 EP 1082463A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- expression products
- genes
- mechanical stress
- stress induced
- products therefrom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8567398P | 1998-05-15 | 1998-05-15 | |
US85673P | 1998-05-15 | ||
PCT/US1999/011066 WO1999060164A1 (en) | 1998-05-15 | 1999-05-14 | Mechanical stress induced genes, expression products therefrom, and uses thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1082463A1 EP1082463A1 (de) | 2001-03-14 |
EP1082463A4 true EP1082463A4 (de) | 2003-05-21 |
EP1082463B1 EP1082463B1 (de) | 2007-01-03 |
Family
ID=22193209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99923223A Expired - Lifetime EP1082463B1 (de) | 1998-05-15 | 1999-05-14 | Durch mechanischen stress induzierte gene, deren expressionsprodukte und deren verwendung. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1082463B1 (de) |
JP (1) | JP2002535956A (de) |
AT (1) | ATE350486T1 (de) |
AU (1) | AU4004699A (de) |
CA (1) | CA2332150A1 (de) |
DE (1) | DE69934688T2 (de) |
IL (2) | IL139637A0 (de) |
WO (1) | WO1999060164A1 (de) |
ZA (1) | ZA200006613B (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020151514A1 (en) * | 1998-05-11 | 2002-10-17 | Paz Einat | Genes associated with mechanical stress, expression products therefrom, and uses thereof |
US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
US7259253B2 (en) | 1999-05-14 | 2007-08-21 | Quark Biotech, Inc. | Genes associated with mechanical stress, expression products therefrom, and uses thereof |
US6528262B1 (en) | 1999-10-06 | 2003-03-04 | Quark Biotech, Inc. | Method for enrichment of natural antisense messenger RNA |
US6986988B2 (en) | 1999-10-06 | 2006-01-17 | Quark Biotech, Inc. | Method for enrichment of natural antisense messenger RNA |
US6468749B1 (en) | 2000-03-30 | 2002-10-22 | Quark Biotech, Inc. | Sequence-dependent gene sorting techniques |
WO2002046753A1 (fr) * | 2000-12-06 | 2002-06-13 | Takara Bio Inc. | Reseau d'adn fonctionnel |
CA2441936A1 (en) * | 2001-03-23 | 2002-10-03 | Yoshihiro Nakatani | Methods and compositions for modulating tumor suppression |
US20030191073A1 (en) | 2001-11-07 | 2003-10-09 | Challita-Eid Pia M. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
BE1014949A3 (fr) | 2001-08-14 | 2004-07-06 | Probiox | Procede de detection de stress oxydant et trousse pour sa mise en oeuvre. |
AU2002361610B2 (en) | 2001-11-07 | 2007-01-11 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
BRPI0411020A (pt) * | 2003-06-06 | 2006-07-18 | Wyeth Corp | perfil de expressão de gene, métodos de identificar agentes modulares do caminho de wnt, de preparar um perfil de expressão de gene, de triar um agente que realce a remodelagem associada com a carga óssea e reagentes que se ligam às proteìnas que modulam a remodelagem óssea e/ou mineralização óssea, de tratar uma doença ou distúrbio de mineralização óssea, de modular a mineralização óssea em uma célula e a mineralização óssea e/ou remodelagem óssea em um paciente e de determinar se um composto ou uma composição realçam o efeito de carga óssea na atividade/função e/ou mineralização da célula óssea, agente candidato para tratar uma condição de massa óssea baixa e composição |
CN101076348A (zh) | 2004-10-08 | 2007-11-21 | 克里纽沃药物有限公司 | 用于在受试者中诱导黑素原生成的组合物和方法 |
US8350009B2 (en) | 2005-03-31 | 2013-01-08 | Agensys, Inc. | Antibodies and related molecules that bind to 161P2F10B proteins |
CA2603093A1 (en) | 2005-03-31 | 2006-10-05 | Agensys, Inc. | Antibodies and related molecules that bind to 161p2f10b proteins |
WO2007022151A2 (en) | 2005-08-15 | 2007-02-22 | Vaxin, Inc. | Immunization of avians by administration of non-replicating vectored vaccines |
FR2893328B1 (fr) * | 2005-11-17 | 2014-01-31 | Lvmh Rech | Procede pour depister des marqueurs impliques dans la resistance de keratinocytes a des deformations mecaniques. |
ES2525476T3 (es) | 2006-08-31 | 2014-12-23 | Clinuvel Pharmaceuticals Limited | Derivados de alfa-MSH para el tratamiento de fotodermatosis |
SI2957292T1 (en) | 2008-03-27 | 2018-04-30 | Clinuvel Pharmaceuticals Limited | Vitiligo therapy |
EP3395361A1 (de) | 2010-02-08 | 2018-10-31 | Agensys, Inc. | An 161p2f10b-proteine bindende antikörper-wirkstoffkonjugate (adc) |
EP2487185A1 (de) | 2011-02-11 | 2012-08-15 | Clinuvel Pharmaceuticals Limited | Hexapeptid mit verbesserter Aktivität bei der Reparatur von zellulärer DNA von Dermiszellen |
ES2645156T3 (es) | 2011-03-21 | 2017-12-04 | Altimmune Inc. | Agente terapéutico inmunológico de acción rápida y prolongada |
HUE035774T2 (en) | 2011-08-12 | 2018-05-28 | Merial Inc | Biological substances, in particular vaccines, preserved by vacuum |
WO2014012090A1 (en) | 2012-07-13 | 2014-01-16 | The Broad Institute, Inc. | Molecular sleds comprising a positively-charged amino acid sequence and a molecular cargo and uses thereof |
EP3494997B1 (de) | 2012-07-25 | 2019-09-18 | The Broad Institute, Inc. | Induzierbare dns-bindende proteine und genomperturbationstools sowie anwendungen davon |
WO2014121104A1 (en) * | 2013-01-31 | 2014-08-07 | The Regents Of The University Of California | Pooled genetic perturbation effects |
US11332719B2 (en) | 2013-03-15 | 2022-05-17 | The Broad Institute, Inc. | Recombinant virus and preparations thereof |
WO2015057671A1 (en) | 2013-10-14 | 2015-04-23 | The Broad Institute, Inc. | Artificial transcription factors comprising a sliding domain and uses thereof |
JP6545084B2 (ja) * | 2015-11-11 | 2019-07-17 | 株式会社Adeka | 潤滑油組成物及びその製造方法 |
WO2022198126A1 (en) * | 2021-03-19 | 2022-09-22 | Washington University | Methods for generating mechanically-responsive cells and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX9204303A (es) * | 1991-07-23 | 1993-11-01 | Rhone Poulenc Rorer Int | Factor regulador del crecimiento de osteoclasto. |
US5445941A (en) * | 1993-06-21 | 1995-08-29 | Eli Lilly And Company | Method for screening anti-osteoporosis agents |
US5763416A (en) * | 1994-02-18 | 1998-06-09 | The Regent Of The University Of Michigan | Gene transfer into bone cells and tissues |
US5834248A (en) * | 1995-02-10 | 1998-11-10 | Millennium Pharmaceuticals Inc. | Compositions and methods using rchd534, a gene uregulated by shear stress |
US5861249A (en) * | 1996-04-23 | 1999-01-19 | Cold Spring Harbor Laboratory | Assays and reagents for identifying modulators of cdc25-mediated mitotic activation |
-
1999
- 1999-05-14 JP JP2000549770A patent/JP2002535956A/ja active Pending
- 1999-05-14 IL IL13963799A patent/IL139637A0/xx unknown
- 1999-05-14 EP EP99923223A patent/EP1082463B1/de not_active Expired - Lifetime
- 1999-05-14 DE DE69934688T patent/DE69934688T2/de not_active Expired - Fee Related
- 1999-05-14 AU AU40046/99A patent/AU4004699A/en not_active Abandoned
- 1999-05-14 WO PCT/US1999/011066 patent/WO1999060164A1/en active IP Right Grant
- 1999-05-14 AT AT99923223T patent/ATE350486T1/de not_active IP Right Cessation
- 1999-05-14 CA CA002332150A patent/CA2332150A1/en not_active Abandoned
-
2000
- 2000-11-13 IL IL139637A patent/IL139637A/en active IP Right Grant
- 2000-11-14 ZA ZA200006613A patent/ZA200006613B/en unknown
Non-Patent Citations (8)
Also Published As
Publication number | Publication date |
---|---|
EP1082463B1 (de) | 2007-01-03 |
CA2332150A1 (en) | 1999-11-25 |
IL139637A0 (en) | 2002-02-10 |
AU4004699A (en) | 1999-12-06 |
ZA200006613B (en) | 2002-02-14 |
EP1082463A1 (de) | 2001-03-14 |
DE69934688D1 (de) | 2007-02-15 |
DE69934688T2 (de) | 2007-10-18 |
WO1999060164A1 (en) | 1999-11-25 |
JP2002535956A (ja) | 2002-10-29 |
IL139637A (en) | 2009-09-22 |
ATE350486T1 (de) | 2007-01-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL139637A0 (en) | Mechanical stress induced genes, expression products therefrom, and uses thereof | |
WO2002040634A3 (en) | Expression miniarrays and uses thereof | |
HUP0401591A2 (hu) | Új receptor-nukleinsavak és- polipeptidek | |
EP0837928A4 (de) | Zusammensetzungen aus rekombinierten poxvirus-cytomegalovirus und ihre verwendung | |
DK1005540T3 (da) | IKK-beta-proteiner, nukleinsyrer og fremgangsmåder | |
DE60233485D1 (de) | Verfahren zur diagnose, behandlung und prävention von knochenverlust | |
EP0831885A4 (de) | Verfahren und verwendung von bindegewebs-wachstumsfaktor als induzierendes mittel | |
WO2000018899A3 (en) | Angiotensin converting enzyme homolog and its use | |
EP1163515A4 (de) | Therapeutische und diagnostische mittel für krankheiter mit gestörter glukose-tolerenz | |
HUP0301581A2 (hu) | Sejteken prezentált peptidek | |
WO1999051186A3 (en) | Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders | |
MXPA03010100A (es) | Tratamiento de la piel. | |
WO2001062784A3 (en) | Use of breast cancer associated membrane proteins (bcmp) for treatment, prophylaxis and diagnosis of breast cancer | |
HUP0003684A2 (hu) | Alzheimer-kór diagnosztizálására szolgáló vizsgálat | |
WO2002018574A3 (en) | Human interleukin-four induced protein | |
PT831899E (pt) | Composições de poxvírus-calicivírus recombinantes e suas utilizações | |
EP1019092A4 (de) | Therapeutische und diagnostische mittel für krankheiten mit gestörter glukose-toleranz | |
SI1565573T1 (sl) | Sonde nukleinske kisline in primerji širokega območja iz regij v topoizomeraznih genih ter postopki, pri katerih jih uporabljamo | |
ATE405649T1 (de) | Hemmstoff zur diagnose und behandlung von haemophilia a patienten | |
WO2003103597A3 (en) | DIAGNOSIS AND TREATMENT OF DIABETES AND INSULIN RESISTANCE | |
EP1078003A4 (de) | Plasmin-inhibitoren aus der australischen braunen schlange (pseudonaja textilis textilis) | |
WO2003103601A3 (en) | DIAGNOSIS AND TREATMENT METHODS FOR DIABETES AND INSULIN RESISTANCE | |
ATE236250T1 (de) | Antisense-sequenzen für die hemmung der expression des adhäsionsmoleküls icam-1 | |
ATE337020T1 (de) | Fettsaure analoge zur diagnose von kranzarterie erkrankungen | |
WO1998051782A3 (en) | Human 3-hydroxyisobutyryl-coenzyme a hydrolase |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20001213 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 12Q 1/68 A, 7C 07K 14/47 B, 7C 12N 15/10 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030404 |
|
17Q | First examination report despatched |
Effective date: 20050225 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070103 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070103 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070103 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070103 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REF | Corresponds to: |
Ref document number: 69934688 Country of ref document: DE Date of ref document: 20070215 Kind code of ref document: P |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070403 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070414 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070604 |
|
NLV1 | Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act | ||
ET | Fr: translation filed | ||
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20071005 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070103 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070404 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070103 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: MC Payment date: 20090514 Year of fee payment: 11 Ref country code: IE Payment date: 20090526 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: LU Payment date: 20090602 Year of fee payment: 11 Ref country code: FR Payment date: 20090513 Year of fee payment: 11 Ref country code: DE Payment date: 20090525 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20090622 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20090518 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20090522 Year of fee payment: 11 |
|
BERE | Be: lapsed |
Owner name: QUARK BIOTECH, INC. Effective date: 20100531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100531 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20100514 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20110131 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100531 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100514 Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20101201 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100514 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100514 |