EP1068362A4 - Compositions contenant des sequences ns5b du virus de l'hepatite c et leurs procedes d'utilisation - Google Patents

Compositions contenant des sequences ns5b du virus de l'hepatite c et leurs procedes d'utilisation

Info

Publication number
EP1068362A4
EP1068362A4 EP99921379A EP99921379A EP1068362A4 EP 1068362 A4 EP1068362 A4 EP 1068362A4 EP 99921379 A EP99921379 A EP 99921379A EP 99921379 A EP99921379 A EP 99921379A EP 1068362 A4 EP1068362 A4 EP 1068362A4
Authority
EP
European Patent Office
Prior art keywords
hepatitis
compositions
methods
virus ns5b
ns5b
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99921379A
Other languages
German (de)
English (en)
Other versions
EP1068362A1 (fr
Inventor
Marc S Collett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Viropharma Biologics LLC
Original Assignee
Viropharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viropharma Inc filed Critical Viropharma Inc
Publication of EP1068362A1 publication Critical patent/EP1068362A1/fr
Publication of EP1068362A4 publication Critical patent/EP1068362A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP99921379A 1998-04-02 1999-04-02 Compositions contenant des sequences ns5b du virus de l'hepatite c et leurs procedes d'utilisation Withdrawn EP1068362A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8050998P 1998-04-02 1998-04-02
US80509P 1998-04-02
US9035698P 1998-06-23 1998-06-23
US90356P 1998-06-23
PCT/US1999/007404 WO1999051781A1 (fr) 1998-04-02 1999-04-02 Compositions contenant des sequences ns5b du virus de l'hepatite c et leurs procedes d'utilisation

Publications (2)

Publication Number Publication Date
EP1068362A1 EP1068362A1 (fr) 2001-01-17
EP1068362A4 true EP1068362A4 (fr) 2005-07-20

Family

ID=26763614

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99921379A Withdrawn EP1068362A4 (fr) 1998-04-02 1999-04-02 Compositions contenant des sequences ns5b du virus de l'hepatite c et leurs procedes d'utilisation

Country Status (6)

Country Link
EP (1) EP1068362A4 (fr)
JP (1) JP2002510509A (fr)
AU (1) AU768177B2 (fr)
CA (1) CA2325016A1 (fr)
IL (1) IL138804A0 (fr)
WO (1) WO1999051781A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6461845B1 (en) * 1995-09-27 2002-10-08 Emory University Recombinant hepatitis C virus RNA replicase
JP2003514562A (ja) * 1999-11-23 2003-04-22 バイロファーマ・インコーポレイテッド ポリメラーゼ組成物およびその使用方法
US7018796B2 (en) 2000-04-07 2006-03-28 Shionogi & Co., Ltd. Preincubation assay methods
WO2001088161A1 (fr) * 2000-05-15 2001-11-22 Tokyo Metropolitan Organization For Medical Research Vecteur permettant d'analyser le mecanisme de replication d'un virus a arn et utilisation de ce vecteur
JP2004520839A (ja) * 2001-03-08 2004-07-15 ベーリンガー インゲルハイム （カナダ） リミテッド Ｈｃｖのｒｎａ依存性ｒｎａポリメラーゼ（ｎｓ５ｂ）の阻害剤を同定するための分析法
EP1256628A3 (fr) * 2001-05-10 2003-03-19 Agouron Pharmaceuticals, Inc. ARN polymerase NS5B du virus de la hepatite C et mutants derivés de la polymerase
WO2005070957A1 (fr) * 2004-01-09 2005-08-04 Merck & Co., Inc. Arn polymerase dependant de l'arn du vhc
WO2009022939A1 (fr) * 2007-08-09 2009-02-19 Uchrezhdenie Rossiiskoi Akademii Nauk Institut Molekulyarnoi Biologii Im. V.A. Engelgardta Ran (Imb Ran) Procédé d'identification du génotype et du sous-type du virus de l'hépatite c sur une biopuce

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037619A1 (fr) * 1995-05-25 1996-11-28 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Procede de reproduction in vitro de l'activite de l'arn-polymerase arn-dependante et de la nucleotidyl-transferase terminale codees par le virus de l'hepatite c (hcv)
WO1997012033A1 (fr) * 1995-09-27 1997-04-03 Emory University Replicase recombinee du virus de l'hepatite c

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
DE69133402T2 (de) * 1990-04-04 2004-11-11 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Protease von hepatitis-c-virus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037619A1 (fr) * 1995-05-25 1996-11-28 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Procede de reproduction in vitro de l'activite de l'arn-polymerase arn-dependante et de la nucleotidyl-transferase terminale codees par le virus de l'hepatite c (hcv)
WO1997012033A1 (fr) * 1995-09-27 1997-04-03 Emory University Replicase recombinee du virus de l'hepatite c

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 20 October 1995 (1995-10-20), ENOMOTO, N.: "Hepatitis C virus (strain HCV-1b, clone HCV-K1-R2), complete genome sequence" *
DATABASE EMBL 5 January 1998 (1998-01-05), LOHMAN ET AL.: "RNA-dependent RNA-polymerase (Fragment)." *
ENOMOTO N ET AL: "COMPARISON OF FULL-LENGTH SEQUENCES OF INTERFERON-SENSITIVE AND RESISTANT HEPATITIS C VIRUS 1B", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 96, no. 1, July 1995 (1995-07-01), pages 224 - 230, XP002910878, ISSN: 0021-9738 *
LOHMANN V ET AL: "BIOCHEMICAL PROPERTIES OF HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE AND INDENTIFICATION OF AMINO ACID SEQUENCE MOTIFS ESSENTIAL FOR ENZYMATIC ACTIVITY", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 71, no. 11, November 1997 (1997-11-01), pages 8416 - 8428, XP002931582, ISSN: 0022-538X *
See also references of WO9951781A1 *

Also Published As

Publication number Publication date
WO1999051781A1 (fr) 1999-10-14
WO1999051781A9 (fr) 2000-05-04
CA2325016A1 (fr) 1999-10-14
AU768177B2 (en) 2003-12-04
IL138804A0 (en) 2001-10-31
EP1068362A1 (fr) 2001-01-17
JP2002510509A (ja) 2002-04-09
AU3861099A (en) 1999-10-25

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20051216