EP1061908A4 - Kombinationstherapie und zusammenstellung für akutes koronarischämiesyndrom und damit zusammenhängende zustände - Google Patents
Kombinationstherapie und zusammenstellung für akutes koronarischämiesyndrom und damit zusammenhängende zuständeInfo
- Publication number
- EP1061908A4 EP1061908A4 EP99911208A EP99911208A EP1061908A4 EP 1061908 A4 EP1061908 A4 EP 1061908A4 EP 99911208 A EP99911208 A EP 99911208A EP 99911208 A EP99911208 A EP 99911208A EP 1061908 A4 EP1061908 A4 EP 1061908A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- combination therapy
- related conditions
- acute coronary
- ischemic syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7790098P | 1998-03-13 | 1998-03-13 | |
US77900P | 1998-03-13 | ||
GBGB9815857.9A GB9815857D0 (en) | 1998-07-21 | 1998-07-21 | Combination therapy for treating preventing or reducing the risks associated with acute coronary ischemic syndrome and related conditions |
GB9815857 | 1998-07-21 | ||
PCT/US1999/005063 WO1999045913A1 (en) | 1998-03-13 | 1999-03-09 | Combination therapy and composition for acute coronary ischemic syndrome and related conditions |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1061908A1 EP1061908A1 (de) | 2000-12-27 |
EP1061908A4 true EP1061908A4 (de) | 2007-01-24 |
Family
ID=26314085
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99911208A Withdrawn EP1061908A4 (de) | 1998-03-13 | 1999-03-09 | Kombinationstherapie und zusammenstellung für akutes koronarischämiesyndrom und damit zusammenhängende zustände |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1061908A4 (de) |
JP (1) | JP2002506024A (de) |
CA (1) | CA2322824A1 (de) |
WO (1) | WO1999045913A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184248B1 (en) * | 1996-09-05 | 2001-02-06 | Robert K. K. Lee | Compositions and methods for treatment of neurological disorders and neurodegenerative diseases |
US7608640B2 (en) | 1999-03-02 | 2009-10-27 | Jallal Messadek | Glycine betaine and its use |
EA200100966A1 (ru) * | 1999-03-11 | 2002-02-28 | Дюпон Фармасьютикалз Компани | ЛЕЧЕНИЕ ТРОМБОЗА КОМБИНИРОВАННЫМ ПРИМЕНЕНИЕМ ИНГИБИТОРА ФАКТОРА Xa И АСПИРИНА, АКТИВАТОРА ТКАНЕВОГО ПЛАЗМИНОГЕНА (TPA), АНТАГОНИСТА GPIIB/IIIA, НИЗКОМОЛЕКУЛЯРНОГО ГЕПАРИНА ИЛИ ГЕПАРИНА |
US6794412B1 (en) | 1999-03-11 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Treatment of thrombosis by combined use of a factor Xa inhibitor and aspirin |
CA2432642A1 (en) | 2000-12-21 | 2002-08-08 | Subhash P. Khanapure | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
BE1015608A6 (fr) | 2003-07-15 | 2005-06-07 | Messadek Jallal | Traitement des arterites. |
ES2364155T3 (es) * | 2002-11-25 | 2011-08-25 | Jallal Messadek | Composiciones de betaína y ácido acetilsalicílico. |
JP2004189711A (ja) * | 2002-12-11 | 2004-07-08 | Raul Altman | 急性冠動脈症候群および関連病態の治療のための抗血小板薬と組合せたメロキシカムの使用 |
US7371759B2 (en) | 2003-09-25 | 2008-05-13 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
US7420059B2 (en) | 2003-11-20 | 2008-09-02 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
WO2006050581A2 (en) | 2004-11-10 | 2006-05-18 | Jallal Messadek | Betaine as agent against arthropod - or mosquito -borne diseases |
WO2006086856A1 (en) | 2005-02-15 | 2006-08-24 | Messadek, Jallal | Combination therapeutic compositions and method of use |
MX2007013486A (es) | 2005-04-27 | 2008-03-14 | Jallal Messadek | Combinaciones de insulinas. |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2105988A (en) * | 1981-09-18 | 1983-04-07 | Rocador Sa | Anti-platelet aggregation dipyridamole with Al aspirin |
WO1997021445A1 (en) * | 1995-12-12 | 1997-06-19 | Omeros Medical Systems, Inc. | Vascular irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis |
WO1997029753A1 (fr) * | 1996-02-19 | 1997-08-21 | Sanofi | Nouvelles associations de principes actifs contenant du clopidogrel et un antithrombotique |
WO1997038986A1 (en) * | 1996-04-12 | 1997-10-23 | G.D. Searle & Co. | Substituted benzenesulfonamide derivatives as prodrugs of cox-2 inhibitors |
WO1997044027A1 (en) * | 1996-05-17 | 1997-11-27 | Merck & Co., Inc. | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases |
WO1997044028A1 (en) * | 1996-05-17 | 1997-11-27 | Merck & Co., Inc. | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases |
WO1997045420A1 (en) * | 1996-05-31 | 1997-12-04 | Merck & Co., Inc. | Process for making phenyl heterocycles useful as cox-2 inhibitors |
WO1998000416A1 (en) * | 1996-07-03 | 1998-01-08 | Merck & Co., Inc. | Process of preparing phenyl heterocycles useful as cox-2 inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5239113A (en) * | 1991-10-15 | 1993-08-24 | Monsanto Company | Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof |
US5250679A (en) * | 1991-10-18 | 1993-10-05 | Genentech, Inc. | Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor |
UA57002C2 (uk) * | 1995-10-13 | 2003-06-16 | Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. | Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування |
IT1276071B1 (it) * | 1995-10-31 | 1997-10-24 | Nicox Ltd | Compositi ad attivita' anti-infiammatoria |
AU2202397A (en) * | 1996-03-28 | 1997-10-17 | G.D. Searle & Co. | Iib/iiia antagonists co-administered with aspirin and/or heparin |
HU224315B1 (hu) * | 1996-06-05 | 2005-07-28 | Gyógyszerkutató Intézet Kft. | Véralvadásgátló hatású peptidil-arginin-aldehid-származékok és a vegyületeket tartalmazó gyógyszerkészítmények |
AU723179B2 (en) * | 1996-07-18 | 2000-08-17 | Merck Canada Inc. | Substituted pyridines as selective cyclooxygenase-2 inhibitors |
-
1999
- 1999-03-09 EP EP99911208A patent/EP1061908A4/de not_active Withdrawn
- 1999-03-09 WO PCT/US1999/005063 patent/WO1999045913A1/en active Application Filing
- 1999-03-09 CA CA002322824A patent/CA2322824A1/en not_active Abandoned
- 1999-03-09 JP JP2000535328A patent/JP2002506024A/ja active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2105988A (en) * | 1981-09-18 | 1983-04-07 | Rocador Sa | Anti-platelet aggregation dipyridamole with Al aspirin |
WO1997021445A1 (en) * | 1995-12-12 | 1997-06-19 | Omeros Medical Systems, Inc. | Vascular irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis |
WO1997029753A1 (fr) * | 1996-02-19 | 1997-08-21 | Sanofi | Nouvelles associations de principes actifs contenant du clopidogrel et un antithrombotique |
WO1997038986A1 (en) * | 1996-04-12 | 1997-10-23 | G.D. Searle & Co. | Substituted benzenesulfonamide derivatives as prodrugs of cox-2 inhibitors |
WO1997044027A1 (en) * | 1996-05-17 | 1997-11-27 | Merck & Co., Inc. | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases |
WO1997044028A1 (en) * | 1996-05-17 | 1997-11-27 | Merck & Co., Inc. | Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases |
WO1997045420A1 (en) * | 1996-05-31 | 1997-12-04 | Merck & Co., Inc. | Process for making phenyl heterocycles useful as cox-2 inhibitors |
WO1998000416A1 (en) * | 1996-07-03 | 1998-01-08 | Merck & Co., Inc. | Process of preparing phenyl heterocycles useful as cox-2 inhibitors |
Non-Patent Citations (1)
Title |
---|
See also references of WO9945913A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999045913A1 (en) | 1999-09-16 |
EP1061908A1 (de) | 2000-12-27 |
JP2002506024A (ja) | 2002-02-26 |
CA2322824A1 (en) | 1999-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20001013 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
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AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20001013;LT PAYMENT 20001013;LV PAYMENT 20001013;MK PAYMENT 20001013;RO PAYMENT 20001013;SI PAYMENT 20001013 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20061227 |
|
17Q | First examination report despatched |
Effective date: 20070810 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080221 |