EP1012333A4 - ISOLIERUNG EINES NEUEN ALTERUNGSFAKTOR-GENS, p23 - Google Patents

ISOLIERUNG EINES NEUEN ALTERUNGSFAKTOR-GENS, p23

Info

Publication number
EP1012333A4
EP1012333A4 EP98938406A EP98938406A EP1012333A4 EP 1012333 A4 EP1012333 A4 EP 1012333A4 EP 98938406 A EP98938406 A EP 98938406A EP 98938406 A EP98938406 A EP 98938406A EP 1012333 A4 EP1012333 A4 EP 1012333A4
Authority
EP
European Patent Office
Prior art keywords
isolation
factor gene
senescence
novel
novel senescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98938406A
Other languages
English (en)
French (fr)
Other versions
EP1012333A1 (de
Inventor
Karen Swisshelm
Suzanne Hosier
Manfred Kubbies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Original Assignee
University of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington filed Critical University of Washington
Publication of EP1012333A1 publication Critical patent/EP1012333A1/de
Publication of EP1012333A4 publication Critical patent/EP1012333A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP98938406A 1997-08-08 1998-08-05 ISOLIERUNG EINES NEUEN ALTERUNGSFAKTOR-GENS, p23 Withdrawn EP1012333A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90887397A 1997-08-08 1997-08-08
US908873 1997-08-08
PCT/US1998/016343 WO1999007893A1 (en) 1997-08-08 1998-08-05 ISOLATION OF A NOVEL SENESCENCE-FACTOR GENE, p23

Publications (2)

Publication Number Publication Date
EP1012333A1 EP1012333A1 (de) 2000-06-28
EP1012333A4 true EP1012333A4 (de) 2003-01-02

Family

ID=25426353

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98938406A Withdrawn EP1012333A4 (de) 1997-08-08 1998-08-05 ISOLIERUNG EINES NEUEN ALTERUNGSFAKTOR-GENS, p23

Country Status (9)

Country Link
EP (1) EP1012333A4 (de)
JP (1) JP2001512698A (de)
KR (1) KR20010022741A (de)
CN (1) CN1270637A (de)
AU (1) AU8693598A (de)
BR (1) BR9811865A (de)
CA (1) CA2296598A1 (de)
TR (1) TR200000331T2 (de)
WO (1) WO1999007893A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2344400T3 (es) * 2000-01-21 2010-08-26 Polymun Scientific Immunbiologische Forschung Gmbh Marcador tumoral y de senescencia.
AU750296B2 (en) * 2000-06-23 2002-07-11 F. Hoffmann-La Roche Ag Antibodies against SEMP1, methods for their production and uses thereof
EP1325020A4 (de) * 2000-09-20 2004-12-15 Human Genome Sciences Inc 21 humane sezernierte proteine
US7125663B2 (en) 2001-06-13 2006-10-24 Millenium Pharmaceuticals, Inc. Genes, compositions, kits and methods for identification, assessment, prevention, and therapy of cervical cancer
US20110105961A1 (en) * 2008-05-23 2011-05-05 Gruber Lewis S Methods, compositions and apparatuses for facilitating regeneration
ES2725852T3 (es) 2010-09-27 2019-09-27 Siwa Corp Eliminación selectiva de células modificadas por AGE para el tratamiento de la aterosclerosis
US8721571B2 (en) 2010-11-22 2014-05-13 Siwa Corporation Selective removal of cells having accumulated agents
ES2908203T3 (es) 2014-09-19 2022-04-28 Siwa Corp Anticuerpos anti-age para el tratamiento de inflamación y trastornos autoinmunes
US10358502B2 (en) 2014-12-18 2019-07-23 Siwa Corporation Product and method for treating sarcopenia
US9993535B2 (en) 2014-12-18 2018-06-12 Siwa Corporation Method and composition for treating sarcopenia
RU2728964C2 (ru) 2016-02-19 2020-08-03 Сива Корпорейшн Способ и композиция для лечения рака, уничтожения метастатических раковых клеток и профилактики метастазов рака, используя антитела к конечным продуктам повышенного гликирования ( AGE)
CN109311975A (zh) 2016-04-15 2019-02-05 Siwa有限公司 用于治疗神经退行性紊乱的抗age抗体
US11213585B2 (en) 2016-06-23 2022-01-04 Siwa Corporation Vaccines for use in treating various diseases and disorders
US10858449B1 (en) 2017-01-06 2020-12-08 Siwa Corporation Methods and compositions for treating osteoarthritis
US10925937B1 (en) 2017-01-06 2021-02-23 Siwa Corporation Vaccines for use in treating juvenile disorders associated with inflammation
US10995151B1 (en) 2017-01-06 2021-05-04 Siwa Corporation Methods and compositions for treating disease-related cachexia
US10961321B1 (en) 2017-01-06 2021-03-30 Siwa Corporation Methods and compositions for treating pain associated with inflammation
CA3059803A1 (en) 2017-04-13 2018-10-18 Siwa Corporation Humanized monoclonal advanced glycation end-product antibody
US11518801B1 (en) 2017-12-22 2022-12-06 Siwa Corporation Methods and compositions for treating diabetes and diabetic complications

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996013610A2 (en) * 1994-10-31 1996-05-09 Geron Corporation Methods and reagents for the identification and regulation of senescence-related genes
WO1999007850A1 (en) * 1997-08-06 1999-02-18 Millennium Biotherapeutics, Inc. Tango-71, tango-73, tango-74, tango-76, and tango-83 nucleic acid molecules and polypeptides
WO1999046281A2 (en) * 1998-03-10 1999-09-16 Genentech, Inc. Novel polypeptides and nucleic acids encoding the same
WO2000000609A2 (en) * 1998-06-29 2000-01-06 Incyte Pharmaceuticals, Inc. Molecules associated with apoptosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580726A (en) * 1994-04-29 1996-12-03 Geron Corporation Method and Kit for enhanced differential display

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996013610A2 (en) * 1994-10-31 1996-05-09 Geron Corporation Methods and reagents for the identification and regulation of senescence-related genes
WO1999007850A1 (en) * 1997-08-06 1999-02-18 Millennium Biotherapeutics, Inc. Tango-71, tango-73, tango-74, tango-76, and tango-83 nucleic acid molecules and polypeptides
WO1999046281A2 (en) * 1998-03-10 1999-09-16 Genentech, Inc. Novel polypeptides and nucleic acids encoding the same
WO2000000609A2 (en) * 1998-06-29 2000-01-06 Incyte Pharmaceuticals, Inc. Molecules associated with apoptosis

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 15 June 1999 (1999-06-15), "Human Tango-73 encoding cDNA", XP002217496, retrieved from EBI Database accession no. AAX19956 *
DATABASE EMBL [online] 15 June 1999 (1999-06-15), "Human Tango-73 protein", XP002217495, retrieved from EBI Database accession no. AAY04143 *
DATABASE EMBL [online] 5 May 2000 (2000-05-05), "cDNA encoding a human molecule associated with apoptosis 2 (MAPOP-2)", XP002217494, retrieved from EBI Database accession no. AAZ60459 *
DATABASE EMBL [online] 7 December 1999 (1999-12-07), "Human PRO944 nucleotide sequence", XP002217498, retrieved from EBI Database accession no. AAZ34118 *
DATABASE EMBL [online] 7 December 1999 (1999-12-07), "Human PRO944 protein sequence", XP002217497, retrieved from EBI Database accession no. AAY41726 *
DATABASE EMBLLEVANT [online] 5 May 2000 (2000-05-05), "A human molecule associated with apoptosis 2 (MAPOP-2)", XP002217493, retrieved from EBI Database accession no. AAY68679 *
FURUSE M ET AL: "CLAUDIN-1 AND -2: NOVEL INTEGRAL MEMBRANE PROTEINS LOCALIZING AT TIGHT JUNCTIONS WITH NO SEQUENCE SIMILARITY TO OCCLUDIN", JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, NEW YORK, US, US, vol. 141, no. 7, 29 June 1998 (1998-06-29), pages 1539 - 1550, XP001008152, ISSN: 0021-9525 *
JONASDOTTIR A. ET AL.: "Refinement of the dominant optic atrophy locus (OPA1) to a 1.4-cM interval on chromosome 3q28-3q29 within a 3-Mb YAC contig", ORIGINAL INVESTIGATION, vol. 99, 1997, pages 115 - 120, XP002217491 *
LINSKENS M H K ET AL: "CATALOGING ALTERED GENE EXPRESSION IN YOUNG AND SENESCENT CELLS USING ENHANCED DIFFERENTIAL DISPLAY", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 23, no. 16, 1995, pages 3244 - 3251, XP002047039, ISSN: 0305-1048 *
See also references of WO9907893A1 *
SMITH D. ET AL.: "Localization of 616 human chromosome 3-specific cosmids using a somatic cell hybrid deletion mapping panel", GENOMICS, vol. 11, September 1991 (1991-09-01), pages 179 - 187, XP001107125 *
SWISSHELM K ET AL: "SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 226, no. 2, 21 January 1999 (1999-01-21), pages 285 - 295, XP004155143, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
EP1012333A1 (de) 2000-06-28
KR20010022741A (ko) 2001-03-26
JP2001512698A (ja) 2001-08-28
AU8693598A (en) 1999-03-01
WO1999007893A1 (en) 1999-02-18
CN1270637A (zh) 2000-10-18
TR200000331T2 (tr) 2000-05-22
CA2296598A1 (en) 1999-02-18
BR9811865A (pt) 2000-08-15

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