EP0977590A4 - Menschliche monoklonale antikörper - Google Patents

Menschliche monoklonale antikörper

Info

Publication number
EP0977590A4
EP0977590A4 EP97913749A EP97913749A EP0977590A4 EP 0977590 A4 EP0977590 A4 EP 0977590A4 EP 97913749 A EP97913749 A EP 97913749A EP 97913749 A EP97913749 A EP 97913749A EP 0977590 A4 EP0977590 A4 EP 0977590A4
Authority
EP
European Patent Office
Prior art keywords
monoclonal antibodies
human monoclonal
human
antibodies
monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97913749A
Other languages
English (en)
French (fr)
Other versions
EP0977590A1 (de
Inventor
Keith Charles Deen
Susan Beth Dillon
Terence Graham Porter
Raymond Whitney Sweet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0977590A1 publication Critical patent/EP0977590A1/de
Publication of EP0977590A4 publication Critical patent/EP0977590A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP97913749A 1996-11-01 1997-10-23 Menschliche monoklonale antikörper Withdrawn EP0977590A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3014996P 1996-11-01 1996-11-01
US30149P 1996-11-01
PCT/US1997/019203 WO1998019704A1 (en) 1996-11-01 1997-10-23 Human monoclonal antibodies

Publications (2)

Publication Number Publication Date
EP0977590A1 EP0977590A1 (de) 2000-02-09
EP0977590A4 true EP0977590A4 (de) 2001-03-14

Family

ID=21852781

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97913749A Withdrawn EP0977590A4 (de) 1996-11-01 1997-10-23 Menschliche monoklonale antikörper

Country Status (4)

Country Link
EP (1) EP0977590A4 (de)
JP (1) JP2001510329A (de)
CA (1) CA2270288A1 (de)
WO (1) WO1998019704A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5280147A1 (es) * 1999-05-18 2003-05-30 Smithkline Beecham Corp Anticuerpo humano monoclonal
JP2003531866A (ja) * 2000-05-03 2003-10-28 メディミューン,インコーポレイテッド 抗体を用いた呼吸器疾患の組合せ治療法
JP2005522996A (ja) * 2001-11-02 2005-08-04 セントカー・インコーポレーテツド Rsvタンパク質、抗体、組成物、方法および使用
GB0210121D0 (en) * 2002-05-02 2002-06-12 Celltech R&D Ltd Biological products
US7070786B2 (en) 2003-06-06 2006-07-04 Centocor, Inc. RSV proteins, antibodies, compositions, methods and uses
US9193780B2 (en) 2008-06-05 2015-11-24 Ablynx N.V. Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases
JP5575377B2 (ja) 2008-07-18 2014-08-20 シスメックス株式会社 抗rsウイルスモノクローナル抗体を用いたrsウイルス検出用キット及びイムノクロマトグラフィー用試験具、並びに新規な抗rsウイルスモノクローナル抗体
CN105061592A (zh) 2009-06-05 2015-11-18 埃博灵克斯股份有限公司 用于预防和/或治疗呼吸道感染的单价、二价和三价抗人呼吸道合胞病毒(hrsv)纳米抗体构建体
EP2507262A1 (de) 2009-11-30 2012-10-10 Ablynx N.V. Verbesserte gegen hrsv gerichtete aminosäuresequenzen und polypeptide damit zur prävention und/oder behandlung von atemwegsinfektionen
JO3555B1 (ar) 2015-10-29 2020-07-05 Merck Sharp & Dohme جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006448A1 (en) * 1992-09-16 1994-03-31 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006448A1 (en) * 1992-09-16 1994-03-31 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9819704A1 *
WYDE P R ET AL: "Evaluation of the protective efficacy of reshaped human monoclonal antibody RSHZ19 against respiratory syncytial virus in cotton rats.", PEDIATRIC RESEARCH, (1995 OCT) 38 (4) 543-50., XP000972993 *

Also Published As

Publication number Publication date
CA2270288A1 (en) 1998-05-14
EP0977590A1 (de) 2000-02-09
JP2001510329A (ja) 2001-07-31
WO1998019704A1 (en) 1998-05-14

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Legal Events

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