EP0941733A3 - Procédés d'hinibition de l'exportation de protéines sans séquence de tête à l'aide de glycosides ou d'aglycones cardiaques et de dérivés - Google Patents
Procédés d'hinibition de l'exportation de protéines sans séquence de tête à l'aide de glycosides ou d'aglycones cardiaques et de dérivés Download PDFInfo
- Publication number
- EP0941733A3 EP0941733A3 EP99100073A EP99100073A EP0941733A3 EP 0941733 A3 EP0941733 A3 EP 0941733A3 EP 99100073 A EP99100073 A EP 99100073A EP 99100073 A EP99100073 A EP 99100073A EP 0941733 A3 EP0941733 A3 EP 0941733A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- inhibiting
- derivatives
- cardiac glycosides
- protein export
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US599895 | 1996-02-12 | ||
US08/599,895 US5891855A (en) | 1996-02-12 | 1996-02-12 | Inhibitors of leaderless protein export |
PCT/US1997/002237 WO1997028808A1 (fr) | 1996-02-12 | 1997-02-12 | Procedes d'inhibition de l'exportation de proteines sans sequence de tete a l'aide de glycosides ou aglycones cardiaques et de derives |
EP97906577A EP0828497B1 (fr) | 1996-02-12 | 1997-02-12 | Procedes d'inhibition de l'exportation de proteines sans sequence de tete a l'aide de glycosides ou aglycones cardiaques et de derives |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97906577A Division EP0828497B1 (fr) | 1996-02-12 | 1997-02-12 | Procedes d'inhibition de l'exportation de proteines sans sequence de tete a l'aide de glycosides ou aglycones cardiaques et de derives |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0941733A2 EP0941733A2 (fr) | 1999-09-15 |
EP0941733A3 true EP0941733A3 (fr) | 1999-12-01 |
Family
ID=24401543
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97906577A Expired - Lifetime EP0828497B1 (fr) | 1996-02-12 | 1997-02-12 | Procedes d'inhibition de l'exportation de proteines sans sequence de tete a l'aide de glycosides ou aglycones cardiaques et de derives |
EP99100073A Withdrawn EP0941733A3 (fr) | 1996-02-12 | 1997-02-12 | Procédés d'hinibition de l'exportation de protéines sans séquence de tête à l'aide de glycosides ou d'aglycones cardiaques et de dérivés |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97906577A Expired - Lifetime EP0828497B1 (fr) | 1996-02-12 | 1997-02-12 | Procedes d'inhibition de l'exportation de proteines sans sequence de tete a l'aide de glycosides ou aglycones cardiaques et de derives |
Country Status (9)
Country | Link |
---|---|
US (4) | US5891855A (fr) |
EP (2) | EP0828497B1 (fr) |
JP (1) | JPH11500454A (fr) |
AT (1) | ATE183922T1 (fr) |
AU (1) | AU706644B2 (fr) |
CA (1) | CA2242245A1 (fr) |
DE (1) | DE69700464T2 (fr) |
ES (1) | ES2140215T3 (fr) |
WO (1) | WO1997028808A1 (fr) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2281925A1 (fr) * | 1997-02-26 | 1998-09-03 | Ciblex Corporation | Inhibiteurs d'exportation de proteine depourvue de sequence initiale |
US6306613B1 (en) | 1997-02-26 | 2001-10-23 | Ciblex Corporation | Modulators of leaderless protein export and methods for identifying and using the same |
US5910484A (en) * | 1997-05-30 | 1999-06-08 | The General Hospital Corporation | Treatment of ischemic cardiac malfunction |
GB9716273D0 (en) | 1997-07-31 | 1997-10-08 | Kimberly Clark Ltd | Hand cleanser |
GB9725480D0 (en) * | 1997-12-01 | 1998-01-28 | Univ London | Cytokines and their use in the treatment of established chronic infections and cancers |
AUPP249298A0 (en) * | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CZ295108B6 (cs) | 1998-03-20 | 2005-05-18 | Benitec Australia Ltd | Syntetický gen obsahující dispergovanou nebo cizorodou deoxyribonukleovou molekulu a genový konstrukt obsahující tento syntetický gen |
JP2002536415A (ja) * | 1999-02-12 | 2002-10-29 | セルパス インコーポレイテッド | 抗腫瘍療法 |
WO2000063364A2 (fr) * | 1999-04-21 | 2000-10-26 | American Home Products Corporation | Procedes et compositions pour l'inhibition de la fonction de sequences polynucleotidiques |
US6423885B1 (en) * | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
IL138529A0 (en) * | 2000-09-18 | 2003-09-17 | Yeda Res & Dev | High level expression of heterologous proteins |
US7112434B2 (en) * | 2001-05-02 | 2006-09-26 | University Of South Florida | Vector system for selection of genes encoding secreted proteins and membrane-bound proteins |
US20040082521A1 (en) * | 2002-03-29 | 2004-04-29 | Azaya Therapeutics Inc. | Novel formulations of digitalis glycosides for treating cell-proliferative and other diseases |
WO2003099011A1 (fr) * | 2002-05-28 | 2003-12-04 | Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Utilisation de glucosides cardiotoniques pour le traitement de la mucovicidose et autres troubles dependant de il-8 |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
US7560528B2 (en) * | 2003-06-20 | 2009-07-14 | Efthimios Ippikoglou | Method of producing recombinant DNA molecules |
WO2005060951A2 (fr) * | 2003-12-19 | 2005-07-07 | Bionaut Pharmaceuticals, Inc. | Argents anti-neoplasiques, therapies de combinaison et techniques associees |
DE102004036047A1 (de) * | 2004-07-24 | 2006-02-23 | Bioghurt Biogarde Gmbh & Co. Kg | Physiologisch aktive Zusammensetzung |
US20080027010A1 (en) * | 2004-09-02 | 2008-01-31 | Bionaut Pharmaceuticals, Inc. | Treatment of refractory cancers using Na+/K+-ATPase inhibitors |
US20060135442A1 (en) * | 2004-09-02 | 2006-06-22 | Bionaut Pharmaceuticals, Inc. | Pancreatic cancer treatment using Na+/K+ ATPase inhibitors |
US20070105790A1 (en) * | 2004-09-02 | 2007-05-10 | Bionaut Pharmaceuticals, Inc. | Pancreatic cancer treatment using Na+/K+ ATPase inhibitors |
US20060135468A1 (en) | 2004-09-02 | 2006-06-22 | Bionaut Pharmaceuticals, Inc. | Treatment of refractory cancers using NA+/K+ ATPase inhibitors |
US20060135441A1 (en) * | 2004-09-02 | 2006-06-22 | Bionaut Pharmaceuticals, Inc. | Combinatorial chemotherapy treatment using Na+/K+ ATPase inhibitors |
EP1812010A2 (fr) * | 2004-10-18 | 2007-08-01 | BTG International Limited | Utilisation d'inhibiteurs de la na+/k+-atpase et leurs antagonistes |
US20060205679A1 (en) * | 2004-10-22 | 2006-09-14 | Azaya Therapeutics, Inc. | Topical and oral formulations of cardiac glycosides for treating skin diseases |
WO2007089688A2 (fr) * | 2006-01-31 | 2007-08-09 | The University Of Toledo | LIGAND Na/K-ATPase |
CN109503584A (zh) | 2006-05-04 | 2019-03-22 | 勃林格殷格翰国际有限公司 | 多晶型 |
EP1852108A1 (fr) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Compositions d'inhibiteurs de la DPP IV |
PE20080251A1 (es) * | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
CN101541319B (zh) | 2006-10-31 | 2013-09-18 | 托莱多大学 | Src和Src家族激酶的Na+/K+-ATP酶特异性肽抑制剂/激活剂 |
WO2009064657A1 (fr) * | 2007-11-13 | 2009-05-22 | Phoenix Biotechnology Inc. | Procédé de détermination de la probabilité d'une réponse thérapeutique dans la chimiothérapie anticancéreuse avec un glycoside cardiaque |
PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
KR101717301B1 (ko) * | 2008-10-14 | 2017-03-16 | 네리엄 바이오테크놀로지, 인크. | 강심 배당체의 추출방법 및 조성물 |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
EP2477494B1 (fr) | 2009-09-16 | 2015-11-11 | The University of Toledo | Ligands de na/k-atpase, antagonistes ouabaïnes, leurs essais et leurs utilisations |
WO2011088210A1 (fr) | 2010-01-13 | 2011-07-21 | The University Of Toledo | Matériaux et méthodes concernant la sodium/potassium adénosine triphosphatase et src |
CN102203112B (zh) | 2010-01-15 | 2014-05-07 | 苏州润新生物科技有限公司 | 某些化合物、组合物及方法 |
US9226960B2 (en) | 2010-04-16 | 2016-01-05 | Andrew B. Bush | FGF modulation of in vivo antibody production and humoral immunity |
US8435525B1 (en) | 2010-04-16 | 2013-05-07 | Andrew B. Bush | FGF modulation of in vivo antibody production and humoral immunity |
AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
WO2012103810A1 (fr) | 2011-02-02 | 2012-08-09 | Suzhou Neupharma Co., Ltd | Certaines entités chimiques, compositions et procédés |
CN102219821A (zh) * | 2011-05-05 | 2011-10-19 | 沈阳药科大学 | 一类强心苷类化合物及其抗肿瘤用途 |
EP3453713B1 (fr) * | 2012-04-29 | 2021-09-08 | Neupharma, Inc. | Dérivés bufadiènolides substitués en position 3 par un groupement amine pour le traitement du cancer |
WO2013169793A2 (fr) * | 2012-05-09 | 2013-11-14 | Ipierian, Inc. | Procédés et compositions pour des protéinopathies tdp-43 |
WO2013171167A1 (fr) | 2012-05-14 | 2013-11-21 | Boehringer Ingelheim International Gmbh | Dérivé de xanthine en tant qu'inhibiteur de dpp-4 pour l'utilisation dans le traitement de troubles associés aux podocytes et/ou un syndrome néphrotique |
US9561245B2 (en) * | 2012-09-06 | 2017-02-07 | The Board Of Regents Of The University Of Texas System | Combination treatments for melanoma |
US9572828B2 (en) | 2013-07-18 | 2017-02-21 | The Board Of Regents Of The University Of Texas System | Treatment for melanoma |
WO2017211979A1 (fr) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinaisons de linagliptine et de metformine |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996004921A1 (fr) * | 1994-08-13 | 1996-02-22 | Hong Keun Chung | INHIBITEUR DE LA SECRETION DU TNFα CONTENANT DE LA SYRINGINE OU SON AGLYCONE |
US5545623A (en) * | 1994-06-10 | 1996-08-13 | Akira Matsumori | Method of inhibiting secretion of inflammatory cytokines |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5872103A (en) * | 1986-11-26 | 1999-02-16 | Belletti; Dino A. | Prevention of mammary tumors by treatment with cardiac glycosides |
US5556963A (en) | 1994-08-05 | 1996-09-17 | Oklahoma Medical Research Foundation | Synthesis of 4-alkoxy-N-acetylneuraminic acid |
US5627195A (en) * | 1995-04-11 | 1997-05-06 | Massachusetts Eye And Ear Infirmary | Treatment for ocular inflammation |
-
1996
- 1996-02-12 US US08/599,895 patent/US5891855A/en not_active Expired - Fee Related
-
1997
- 1997-02-12 DE DE69700464T patent/DE69700464T2/de not_active Expired - Fee Related
- 1997-02-12 AT AT97906577T patent/ATE183922T1/de not_active IP Right Cessation
- 1997-02-12 ES ES97906577T patent/ES2140215T3/es not_active Expired - Lifetime
- 1997-02-12 AU AU21231/97A patent/AU706644B2/en not_active Ceased
- 1997-02-12 EP EP97906577A patent/EP0828497B1/fr not_active Expired - Lifetime
- 1997-02-12 EP EP99100073A patent/EP0941733A3/fr not_active Withdrawn
- 1997-02-12 WO PCT/US1997/002237 patent/WO1997028808A1/fr active IP Right Grant
- 1997-02-12 JP JP9528759A patent/JPH11500454A/ja active Pending
- 1997-02-12 CA CA002242245A patent/CA2242245A1/fr not_active Abandoned
-
1998
- 1998-12-14 US US09/211,290 patent/US6071885A/en not_active Expired - Fee Related
-
1999
- 1999-05-28 US US09/322,676 patent/US6107283A/en not_active Expired - Fee Related
- 1999-12-17 US US09/466,036 patent/US6281197B1/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545623A (en) * | 1994-06-10 | 1996-08-13 | Akira Matsumori | Method of inhibiting secretion of inflammatory cytokines |
WO1996004921A1 (fr) * | 1994-08-13 | 1996-02-22 | Hong Keun Chung | INHIBITEUR DE LA SECRETION DU TNFα CONTENANT DE LA SYRINGINE OU SON AGLYCONE |
Non-Patent Citations (3)
Title |
---|
BROOKS ET AL.: "Protein secretion by the rat epididymis can be selectively modified in vitro by local anesthetics, glucose privation, dinitrophenol, ouabain and ionophores", J. ANROL., vol. 5, no. 5, 1984, pages 351 - 360, XP002034262 * |
CRUTCHLEY ET AL.: "Monovalent cation dependence of tissue plasminogen activator synthesis by HELA cells", J. BIOL. CHEM., vol. 262, no. 7, 5 March 1987 (1987-03-05), pages 3017 - 3021, XP002034261 * |
FLOKIEWICZ ET AL.: "Quantitative export of FGF-2 occurs through an alternative, energy-dependent, non-ER/Golgi pathway", J. CELL. PHYSIOL., vol. 162, no. 3, March 1995 (1995-03-01), pages 388 - 399, XP000676621 * |
Also Published As
Publication number | Publication date |
---|---|
DE69700464T2 (de) | 2000-04-06 |
EP0828497B1 (fr) | 1999-09-01 |
AU706644B2 (en) | 1999-06-17 |
EP0941733A2 (fr) | 1999-09-15 |
CA2242245A1 (fr) | 1997-08-14 |
JPH11500454A (ja) | 1999-01-12 |
DE69700464D1 (de) | 1999-10-07 |
US6281197B1 (en) | 2001-08-28 |
AU2123197A (en) | 1997-08-28 |
US6107283A (en) | 2000-08-22 |
ES2140215T3 (es) | 2000-02-16 |
ATE183922T1 (de) | 1999-09-15 |
EP0828497A1 (fr) | 1998-03-18 |
WO1997028808A1 (fr) | 1997-08-14 |
US6071885A (en) | 2000-06-06 |
US5891855A (en) | 1999-04-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0941733A3 (fr) | Procédés d'hinibition de l'exportation de protéines sans séquence de tête à l'aide de glycosides ou d'aglycones cardiaques et de dérivés | |
NO20002957D0 (no) | Behandling med anti-ErbB2-antistoffer | |
DE69014478T2 (de) | Regelungsanordnung für eine sitzheizung. | |
HK1000786A1 (en) | Dna constructs for endogenous gene activation and expression modification. | |
DK0736532T3 (da) | Pyrido[3,2-e]pyrazinoner med antiastmatisk virkning og fremgangsmåde til deres fremstilling | |
DE68906550D1 (de) | Individuelle blattsteuerung fuer helikopter. | |
NO902750D0 (no) | Fremgangsmaate til fremstilling av 3,5,6-substituerte derivater av 1,2-0-isopropyliden-alfa-glukofuranose og mellomprodukter for fremstilling av derivatene. | |
NO875358L (no) | 6-benzoksazinyl- og 6-benzotiazinyl-2,3,4,5-tetrahydropyridazin-3-oner og fremgangsmaate for deres fremstilling. | |
GR1000519B (el) | Παραγωγα ερυθρομυκινης. | |
AU3524995A (en) | Method for treatment of cancers by regulating the activity of ras proteins | |
DE68900210D1 (de) | Pyranobenzoxadiazolderivate, herstellung, verwendung und diese enthaltende zubereitungen. | |
NO882940D0 (no) | Fremgangsmaate for fremstilling av castanosperminestere og glycosider. | |
IT8721841A0 (it) | Metodo per realizzare mobili, particolarmente poltrone, divani o simili, da fogli di feltro trattati con sostanze indurenti e mobili relativi | |
DK315387A (da) | Androst-4-en-3,17-dioner og fremgangsmaade til fremstilling deraf | |
OA09128A (en) | Platinum- (IV) -diamine complex, method for the preparation of this compound, preparation with an anti-tumour action, which contains at least one platinum compound, and shaped preparations with an anti-tumour action. | |
AU599133B2 (en) | Novel substituted (4.2.0.)bicyclooctane derivatives with valuable therapeutic properties | |
NO903484D0 (no) | Substituerte pyrazinderivater og fremgangsmaate for deres fremstilling. | |
NO894697D0 (no) | Penemderivater og fremgangsmaater for deres fremstilling. | |
NO893565L (no) | Etansulfonamidderivater og fremgangsmaate for deres fremstilling. | |
DK684987A (da) | Amycin og derivater deraf, fremgangsmaade til deres fremstilling og deres anvendelse samt mikroorganisme | |
NO872885D0 (no) | 1,3,5-tritianderivater og fremgangsmaate for dens fremstilling. | |
AU4857796A (en) | Sex-specific dna probe for parrots, methods and kits | |
IT8947916A0 (it) | Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoil derivato della d-carnitina | |
IT8560383V0 (it) | Pannello o sportello-antina curvo per mobili. | |
IT1210232B (it) | Dispositivo di bloccaggio di ante accoppiate girevoli, specialmente per mobili. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990105 |
|
AC | Divisional application: reference to earlier application |
Ref document number: 828497 Country of ref document: EP |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20010901 |