EP0906448A4 - Methoden zur diagnose und prognose von krebs - Google Patents

Methoden zur diagnose und prognose von krebs

Info

Publication number
EP0906448A4
EP0906448A4 EP97920115A EP97920115A EP0906448A4 EP 0906448 A4 EP0906448 A4 EP 0906448A4 EP 97920115 A EP97920115 A EP 97920115A EP 97920115 A EP97920115 A EP 97920115A EP 0906448 A4 EP0906448 A4 EP 0906448A4
Authority
EP
European Patent Office
Prior art keywords
cancer
methods
prb2
mutations
predict
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP97920115A
Other languages
English (en)
French (fr)
Other versions
EP0906448B1 (de
EP0906448A1 (de
Inventor
Antonio Giordano
Alfonso Baldi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GIORDANO, ANTONIO
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP08009585A priority Critical patent/EP2014772A3/de
Publication of EP0906448A1 publication Critical patent/EP0906448A1/de
Publication of EP0906448A4 publication Critical patent/EP0906448A4/de
Application granted granted Critical
Publication of EP0906448B1 publication Critical patent/EP0906448B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4736—Retinoblastoma protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G01N33/5752—
    • G01N33/57545—
    • G01N33/5755—
    • G01N33/5758—
    • G01N33/5759—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
EP97920115A 1996-04-05 1997-04-03 Methoden zur diagnose und prognose von krebs Expired - Lifetime EP0906448B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08009585A EP2014772A3 (de) 1996-04-05 1997-04-03 Verfahren zur Diagnose und Prognose von Krebs

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US1494396P 1996-04-05 1996-04-05
US14943P 1996-04-05
US1937296P 1996-06-05 1996-06-05
US19372P 1996-06-05
US2019696P 1996-06-21 1996-06-21
US20196P 1996-06-21
US3953297P 1997-03-03 1997-03-03
US39532P 1997-03-03
PCT/US1997/005598 WO1997038125A1 (en) 1996-04-05 1997-04-03 Methods for the diagnosis and prognosis of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP08009585A Division EP2014772A3 (de) 1996-04-05 1997-04-03 Verfahren zur Diagnose und Prognose von Krebs

Publications (3)

Publication Number Publication Date
EP0906448A1 EP0906448A1 (de) 1999-04-07
EP0906448A4 true EP0906448A4 (de) 2004-12-01
EP0906448B1 EP0906448B1 (de) 2009-02-25

Family

ID=27486431

Family Applications (2)

Application Number Title Priority Date Filing Date
EP08009585A Withdrawn EP2014772A3 (de) 1996-04-05 1997-04-03 Verfahren zur Diagnose und Prognose von Krebs
EP97920115A Expired - Lifetime EP0906448B1 (de) 1996-04-05 1997-04-03 Methoden zur diagnose und prognose von krebs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP08009585A Withdrawn EP2014772A3 (de) 1996-04-05 1997-04-03 Verfahren zur Diagnose und Prognose von Krebs

Country Status (7)

Country Link
EP (2) EP2014772A3 (de)
JP (2) JP2000510330A (de)
AT (1) ATE423852T1 (de)
AU (1) AU2438997A (de)
CA (1) CA2250854C (de)
DE (1) DE69739276D1 (de)
WO (1) WO1997038125A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19882435B4 (de) * 1997-06-02 2007-09-20 Thomas Jefferson University Verfahren zur Hemmung von Krebszellwachstum mit einem pRb2/p130 exprimierenden Vektor
JP2002523760A (ja) 1998-09-02 2002-07-30 ダイアデクスアス・インコーポレーテッド 様々な癌を診断、監視、段階づけ、造影及び治療する新規な方法
US6261778B1 (en) * 1998-10-22 2001-07-17 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode SCP proteins, and uses thereof
AU2001275437A1 (en) * 2000-06-09 2001-12-17 Idec Pharmaceuticals Corporation Gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
JP2006503574A (ja) * 2002-10-22 2006-02-02 カン−フィテ・バイオファーマ・リミテッド 疾患の状態に関するマーカーとしてのａ３ａｒ
RU2007139516A (ru) * 2005-03-25 2009-04-27 Дженентек, Инк. (Us) Мутации с-мет при раке легких
RU2404193C2 (ru) 2005-03-25 2010-11-20 Дженентек, Инк. Способ лечения опухоли у субъекта

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015602A1 (en) * 1991-02-28 1992-09-17 Dana-Farber Cancer Institute, Inc. Cancer diagnosis and therapy
WO1992021771A1 (en) * 1991-06-03 1992-12-10 Triton Diagnostics, Inc. Epidermal growth factor receptor ectodomain
WO1995024503A1 (en) * 1994-03-07 1995-09-14 Rapaport, Erich Sensitive cancer test

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE120497T1 (de) 1988-05-09 1995-04-15 Univ Temple Verfahren zur voraussage der wirksamkeit einer antineoplastichen behandlung bei einzelnen patienten.
DE69019410T2 (de) * 1989-03-31 1995-10-05 Canji Inc Retinoblastoma-Genprodukt-Antikörper und deren Verwendungen.
US5234811A (en) * 1991-09-27 1993-08-10 The Scripps Research Institute Assay for a new gaucher disease mutation
CA2096497A1 (en) * 1992-05-26 1993-11-27 Patricia Anne Spears Mycobacteria probes
WO1994011531A1 (en) * 1992-11-13 1994-05-26 California Institute Of Biological Research Identification of neoplasms by detection of genetic insertions and deletions
WO1995002328A1 (en) * 1993-07-15 1995-01-26 Indiana University Foundation Mammalian low molecular weight phospholipase a2 nucleotide and amino acid sequences

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015602A1 (en) * 1991-02-28 1992-09-17 Dana-Farber Cancer Institute, Inc. Cancer diagnosis and therapy
WO1992021771A1 (en) * 1991-06-03 1992-12-10 Triton Diagnostics, Inc. Epidermal growth factor receptor ectodomain
WO1995024503A1 (en) * 1994-03-07 1995-09-14 Rapaport, Erich Sensitive cancer test

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
CLAUDIO P P ET AL: "P120/PRB2 HAS GROWTH SUPPRESSIVE PROPORTIES SIMILAR TO YET DISTINCTIVE FROM THOSE OF RETINOBLASTOMA FAMILY MEMBERS PRB AND P107", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 54, no. 21, 1 November 1994 (1994-11-01), pages 5556 - 5560, XP002910339, ISSN: 0008-5472 *
DEPASQUALE S E ET AL: "DIFFERENTIAL EXPRESSION OF THE RB2 TUMOR SUPPRESSOR GENE IN HUMAN EPITHELIAL OVARIAN CARCINOMA", LABORATORY INVESTIGATION, UNITED STATES AND CANADIAN ACADEMY OF PATHOLOGY, BALTIMORE,, US, vol. 76, no. 1, 1 March 1997 (1997-03-01), pages 98A, XP008008523, ISSN: 0023-6837 *
HANNON G J ET AL: "Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins.", GENES & DEVELOPMENT. DEC 1993, vol. 7, no. 12A, December 1993 (1993-12-01), pages 2378 - 2391, XP009034493, ISSN: 0890-9369 *
HONG F D ET AL: "Structure of the human retinoblastoma gene.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. JUL 1989, vol. 86, no. 14, July 1989 (1989-07-01), pages 5502 - 5506, XP001182757, ISSN: 0027-8424 *
KHALIFA A ET AL: "The value of tumor markers in the diagnosis, staging and prognosis of lung cancer", CANCER MOLECULAR BIOLOGY 1995 EGYPT, vol. 2, no. 3, 1995, pages 541 - 547, XP009034802, ISSN: 1110-5313 *
PICARDO A L ET AL: "Quantitative analysis of carcinoembryonic antigen, squamous cell carcinoma antigen, CA 125, and CA 50 cytosolic content in non-small cell lung cancer", CANCER 1994 UNITED STATES, vol. 73, no. 9, 1994, pages 2305 - 2311, XP009034800, ISSN: 0008-543X *
XU H J ET AL: "Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma.", JOURNAL OF THE NATIONAL CANCER INSTITUTE. 4 MAY 1994, vol. 86, no. 9, 4 May 1994 (1994-05-04), pages 695 - 699, XP009034424, ISSN: 0027-8874 *

Also Published As

Publication number Publication date
EP0906448B1 (de) 2009-02-25
EP0906448A1 (de) 1999-04-07
AU2438997A (en) 1997-10-29
ATE423852T1 (de) 2009-03-15
CA2250854A1 (en) 1997-10-16
EP2014772A3 (de) 2009-05-27
WO1997038125A1 (en) 1997-10-16
EP2014772A2 (de) 2009-01-14
DE69739276D1 (de) 2009-04-09
JP2000510330A (ja) 2000-08-15
CA2250854C (en) 2011-06-21
EP2014772A8 (de) 2009-04-29
JP2008283985A (ja) 2008-11-27

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