EP0857142A1 - Remplissage d'emballages pharmaceutiques a compartiments multiples - Google Patents

Remplissage d'emballages pharmaceutiques a compartiments multiples

Info

Publication number
EP0857142A1
EP0857142A1 EP95934034A EP95934034A EP0857142A1 EP 0857142 A1 EP0857142 A1 EP 0857142A1 EP 95934034 A EP95934034 A EP 95934034A EP 95934034 A EP95934034 A EP 95934034A EP 0857142 A1 EP0857142 A1 EP 0857142A1
Authority
EP
European Patent Office
Prior art keywords
computer
robot arm
packaged
individual chambers
filling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP95934034A
Other languages
German (de)
English (en)
Other versions
EP0857142B1 (fr
Inventor
Matthias Vogelsanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fleximation AG
Original Assignee
Fleximation AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fleximation AG filed Critical Fleximation AG
Publication of EP0857142A1 publication Critical patent/EP0857142A1/fr
Application granted granted Critical
Publication of EP0857142B1 publication Critical patent/EP0857142B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/12—Introducing successive articles, e.g. confectionery products, of different shape or size in predetermined positions

Definitions

  • the invention relates to a method for automatically filling pharmaceutical multi-body packaging for clinical studies according to the preamble of patent claim 1 and a device for carrying out this method according to the preamble of patent claim 6.
  • the aforementioned method is further developed by the features of the characterizing part of independent claim 1 and the device provided for this purpose by the features of the characterizing part of independent claim 6.
  • the products to be packaged are fed from a container, preferably by means of vibration technology, or by gravitational action via a movable feed, such as e.g. a flexible spring tube to the robot arm.
  • a movable feed such as e.g. a flexible spring tube
  • the robot arm brings the feed to the desired position in the packaging, whereupon the product is inserted in a targeted manner.
  • the products can be stowed in the movable feeder and mechanically separated before loading if the product to be packaged so requires.
  • the advantage can be achieved - thanks to the free programmability - of producing multi-chamber packagings with different product contents without retrofitting work.
  • the programming of the automatic filling process can in principle be carried out in various ways, which are described below.
  • the insertion points in the packaging are displayed on a screen.
  • the operator assigns the desired product to the intended insertion point (eg blister yard) with a pointing device (eg mouse).
  • a program ensures that the filling units receive the corresponding driving commands, so that the search control can then run the process independently.
  • a camera with an image processing system can be used to record the insertion points, or the packaging layout can be adopted by a CAD program.
  • a preferred development of the invention consists in that after the individual chambers have been filled by means of an electronic image processing device, a comparison is made between the filling obtained and the programmed specification, so that the corresponding defective multi-chamber packaging can be eliminated in the event of a deviation.
  • FIG. 1 shows a schematic representation of a device according to the invention for a single product
  • FIG. 2 shows a schematic representation of a device according to the invention for three different products.
  • the device according to the invention shown in FIG. 1 consists of a storage container 1 for the product to be packaged, a transport means 2 for the product to be packaged in the form of a vibrating device, a movable feed line 3 for the product to be packaged, in the form of a flexible spiral tube and one, which engages at the free end of the feed line 3 in two mutually orthogonal, freely programmable traversing axes, movable robot arm 5.
  • the robot arm 5 is controlled by a computer 7.
  • the robot arm 5 can also have only one or more than two freely programmable travel axes.
  • a 2-axis configuration with Cartesian XY kinematics is preferably used, which allows the products in the plane to be optionally introduced into the blister pockets of the multi-chamber packaging 6 according to a production program.
  • the traversing axes can be driven, for example, by a servo motor that converts the rotary movement into a linear movement via a spiral spindle.
  • a third vertically arranged axis or a pneumatically driven lifting element can be used if the product to be packaged so requires.
  • the different axes of the robot arm 5 can be controlled individually or in a coordinated manner by means of a path control that is common on the market.
  • the control also takes over the storage of the production program.
  • a plurality of filling units 10 can also be combined with one another in order to insert different products in a single multi-chamber packaging 6. If several filling units 10 are combined, the multi-chamber packaging 6 can be transported between the filling units 10 in cycles or continuously. In the first case, the multi-chamber packaging 6 stands still during the insertion process, in the second case the computer can be controlled
  • FIG. 2 shows a device according to the invention with three filling units 10 in order to automatically and flexibly pack test samples with different product assignments.
  • the multi-chamber packaging 6 is shaped in the form of Busters from roll material and transported to the filling section 9, where a filling unit 10 places a product type according to the production program stored in the computer 7.
  • a camera 4 (FIG. 1) with electronic image processing system arranged after each filling unit 10 above the multi-chamber packs 6, after automatic filling, checks whether the filling process has been carried out in accordance with the programmed specification.
  • the filled multi-chamber packagings 6 are transported further on the filling section 9, provided with a cover film at the station 12 and on the station 13 cut.
  • One or more computers 7 control the molding station 8, the filling units 10, the stations 12 and 13, and the cameras 4 with an image processing system.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Container Filling Or Packaging Operations (AREA)

Abstract

L'invention concerne un procédé de remplissage automatique d'emballages pharmaceutiques à compartiments multiples pour des études cliniques. Les emballages à compartiments multiples sont constitués d'une pluralité de compartiments individuels disposés dans un plan, sous la forme, par exemple, d'une plaquette alvéolaire. Les produits à emballer sont amenés à chaque fois depuis un réservoir (1) au moyen d'un dispositif de transport (2) circulant dans une conduite (3) d'alimentation mobile, l'extrémité libre de ladite conduite étant guidée jusqu'au compartiment souhaité au moyen d'un bras (4) de robot qui se meut parallèlement au plan des compartiments. Le produit à emballer est alors introduit dans le compartiment souhaité, la commande des différentes opérations étant réalisée par un ordinateur (6). Le bras (4) de robot dispose d'au moins un axe de mobilité librement programmable de telle façon que les produits à emballer peuvent être transportés et introduits dans le compartiment prédéterminé dans le plan conformément à un programme librement sélectionné pouvant être mémorisé dans l'ordinateur (6).
EP95934034A 1995-10-23 1995-10-23 Remplissage d'emballages pharmaceutiques a compartiments multiples Expired - Lifetime EP0857142B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH1995/000247 WO1997015494A1 (fr) 1995-10-23 1995-10-23 Remplissage d'emballages pharmaceutiques a compartiments multiples

Publications (2)

Publication Number Publication Date
EP0857142A1 true EP0857142A1 (fr) 1998-08-12
EP0857142B1 EP0857142B1 (fr) 1999-08-11

Family

ID=4549984

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95934034A Expired - Lifetime EP0857142B1 (fr) 1995-10-23 1995-10-23 Remplissage d'emballages pharmaceutiques a compartiments multiples

Country Status (4)

Country Link
US (1) US6115990A (fr)
EP (1) EP0857142B1 (fr)
DE (1) DE59506611D1 (fr)
WO (1) WO1997015494A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU742980B2 (en) * 1999-10-13 2002-01-17 Kawasaki Jukogyo Kabushiki Kaisha Random work arranging device
ES2570739T3 (es) * 2000-03-31 2016-05-20 Mts Medication Tech Inc Máquina de envasado automático de productos farmacéuticos sólidos
ES2246599B1 (es) * 2002-03-26 2006-11-01 Grifols, S.A. Procedimiento y aparato para el control del envasado en condiciones asepticas.
BR0314155A (pt) 2002-09-09 2005-07-05 Arbor Vita Corp Métodos para diagnosticar câncer cervical
EP3323405A1 (fr) * 2006-09-11 2018-05-23 Synergie Medicale BRG INC. Système et procédé de distribution de médicaments
EP2062822A1 (fr) * 2007-11-24 2009-05-27 UHLMANN PAC-SYSTEME GmbH & Co. KG Procédé et dispositif de remplissage individuel de blisters
US8781616B2 (en) 2011-06-27 2014-07-15 The Procter & Gamble Company Robotic unscrambler and method
US9394070B2 (en) * 2012-10-08 2016-07-19 Pearson Medical Technologies, Llc Pill packaging machine
US10293963B2 (en) 2016-01-29 2019-05-21 Carefusion Germany 326 Gmbh Filling station and method for filling a transport tray

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080033A (en) * 1962-08-15 1963-03-05 Northern Electric Co Sorting apparatus
US3530639A (en) * 1968-11-12 1970-09-29 Merrill Machinery Co Pill box filler
US3889447A (en) * 1973-05-24 1975-06-17 Smithkline Corp Quality control monitor for medicinal capsule packaging apparatus
IT1145011B (it) * 1981-01-23 1986-11-05 Ima Spa Apparecchiatura per il controllo delle operazioni lungo la linea operativa di macchine confezionatrici, particolarmente di confezioni-"blisters" e simili
CH655698A5 (fr) * 1984-03-15 1986-05-15 Sapal Plieuses Automatiques Installation pour le remplissage avec differentes sortes de produits, de barquettes preformees pour boites d'assortiments.
DE3513507A1 (de) * 1984-05-09 1985-11-14 "LOESCH"-Verpackungstechnik GmbH & Co KG, 8602 Altendorf Vorrichtung zum einlegen von pralinen
US4655026A (en) * 1985-12-11 1987-04-07 Wigoda Luis T Pill dispensing machine
DE3704423A1 (de) * 1987-02-12 1988-08-25 Lesch Hans Bernd Verfahren und vorrichtung zum vollautomatischen einlegen von gegenstaenden, insbesondere pralinen, in eine verpackungseinheit
DE3709015A1 (de) * 1987-03-19 1988-10-20 Fraunhofer Ges Forschung Vorrichtung zum orientierungsbestimmten und positionierten ablegen von kleinteilen
US4881356A (en) * 1988-01-25 1989-11-21 Stelron Components Apparatus for assembling multi-part article
DE4208818C2 (de) * 1992-03-19 1994-09-08 Haensel Otto Gmbh Verfahren und Vorrichtung zum Einlegen von Artikeln in Verpackungseinsätze
DE19617014C2 (de) * 1996-04-27 1998-04-09 Uhlmann Pac Systeme Gmbh & Co Verfahren und Vorrichtung zum Nachfüllen von Füllgut in Näpfe einer Folienbahn

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9715494A1 *

Also Published As

Publication number Publication date
WO1997015494A1 (fr) 1997-05-01
DE59506611D1 (de) 1999-09-16
US6115990A (en) 2000-09-12
EP0857142B1 (fr) 1999-08-11

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