EP0851774A1 - Spritzenkolben mit lineargetriebe - Google Patents

Spritzenkolben mit lineargetriebe

Info

Publication number
EP0851774A1
EP0851774A1 EP96919518A EP96919518A EP0851774A1 EP 0851774 A1 EP0851774 A1 EP 0851774A1 EP 96919518 A EP96919518 A EP 96919518A EP 96919518 A EP96919518 A EP 96919518A EP 0851774 A1 EP0851774 A1 EP 0851774A1
Authority
EP
European Patent Office
Prior art keywords
syringe
aggregate
syringe body
seal
syringe plunger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96919518A
Other languages
English (en)
French (fr)
Inventor
Jean-Claude Berney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0851774A1 publication Critical patent/EP0851774A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod

Definitions

  • the plunger-syringe system In all areas where liquids have to be dispensed, the plunger-syringe system is widely used and appreciated for its ease of use. In the medical field in particular, it is universally widespread for practicing drug injections. In the majority of cases, these are short-term manual injections where the injection speed does not have to be precisely controlled. However, there are more and more frequent cases where the drugs must no longer be injected but infused, that is to say administered slowly over time, and this in a perfectly measured manner. For this there are different types of pumps whose flow can be programmed precisely. One of the solutions consists in using a "syringe pump", that is to say a motorized system making it possible to linearly push the piston at a speed corresponding to the desired flow rate.
  • a first problem resides in the filling system of the syringe. Using pre-filled syringes limits potential uses of the system. Furthermore, the use of an overly sophisticated system can be penalizing. It is therefore beneficial to get as close as possible to the current filling system which is easy to assimilate, quick and efficient.
  • a second problem lies in the means of linear transmission between the motorization system and the piston.
  • these means are integral with the motorization system and it is necessary to reset them to 0 before any new use, which represents a relatively complex additional manipulation.
  • disposable type means provided for a single use. It is therefore important that the filling and commissioning operations of the device remain very simple. It is the aim of the present invention to provide an effective solution to this problem.
  • a syringe plunger for infusion comprising a seal intended to seal between the syringe body and the plunger, the latter being characterized in that it comprises an aggregate formed by a plurality of mechanical parts comprising at less linear transmission means arranged to be driven by external control and motorization means and a support for these transmission means, said piston also comprising removable means arranged so as to be able to freely move said aggregate inside the body syringe before commissioning, and means arranged to fix the aggregate at least indirectly to the syringe body during commissioning.
  • Figures la and lb show by way of example a syringe plunger according to the invention in the pushed position and in the pulled position.
  • FIG. 2 shows by way of example the piston with its seal and the mechanical unit with its support, its linear transmission means and a removable pull tab for carrying out the filling operations before putting into service.
  • Figures 3a and 3b show the piston fixed by the syringe body by an intermediate fastener in the starting position and in the fully deployed position.
  • FIG. 4 shows by way of example a double action filling puller for piston according to the invention.
  • FIG. 5 shows by way of example coding means making it possible to transmit to the control and motorization means information concerning the characteristics of the piston.
  • Figures la and lb show a syringe body 1 which can be a standard syringe body as currently used for the injection of medicaments or other liquid substances.
  • a piston comprising the seal 2 making it possible to seal between the syringe body 1 and the piston.
  • This seal 2 is mounted on a mechanical aggregate 3.
  • This aggregate 3 comprises, among other things, linear transmission means formed by a combination of mother screws 4 and a support 5.
  • This support 5 slides freely in the syringe body 1, so much so that the friction force between the piston and the syringe body is given essentially by the friction of the seal 2 on the syringe body 1.
  • a removable pull tab 6 makes it possible to move the entire piston.
  • the piston is in the pushed position ez the volume of the reservoir formed between the syringe body 1 and the seal 2 is practically zero.
  • FIG. 2 we have an example of a piston according to the invention on which we find the seal 20 and the mechanical aggregate comprising the support 21.
  • a lead screw 22 driven by a transmission wheel 23.
  • a first telescopic element 24 on which is mounted a second telescopic element 25.
  • the seal 20 is mounted on the telescopic element 25.
  • the elements 22, 24 and 25 have the same pitch and all of the elements 22, 23, 24 and 25 form the means of linear transmission.
  • the telescopic elements 24 and 25 deploy linearly at a speed which is directly proportional to the speed of rotation of the mother screw 22.
  • the seal must not be rotated, which may be the case if the section of the syringe body is circular.
  • a guide system formed for example of an intermediate part 26 which is deployed between the telescopic element 25 which carries the seal 20 and the support 21, and prevents these two parts from rotating one by compared to each other.
  • the piston comprises a metallic piece of annular shape 27 fixed on the support 21. This piece makes it possible to fix the aggregate to the syringe body as we will describe later.
  • the aggregate is fixed relative to the syringe body, which could be done with fixing means integrated directly in the support of the aggregate .
  • the aggregate is fixed by its support 35 inside an intermediate fixing piece 36.
  • This piece has an annular magnet 37.
  • this magnet 37 comes opposite the annular metal part 38 of the support. If this part is for example made of ferrous metal, the magnetic force of retention enters the magnet 37 and the metal part 38 makes it possible to fix the aggregate to the intermediate fixing part 36.
  • this intermediate piece 36 can be attached to the syringe body by a bayonet system 39 as is commonly done when using syringes with compressed air.
  • the aggregate was indirectly attached to the syringe body by means of the fixing part 36.
  • the control and motorization means are also fixed to this intermediate part 36. The latter can therefore serve as an adapter . It would thus be possible to use the same control and motorization means with pistons and syringe bodies of different dimensions and capacities, 10 cc, 20 cc, 50 cc, using intermediate pieces 36 of suitable configuration.
  • Figure 3a shows the starting position. In this position, the linear transmission means formed by the lead screw and the two telescopic elements are completely folded back so that the reservoir formed between the syringe body and the seal is maximum.
  • Figure 3b shows the final position. In this position the linear transmission means are fully deployed and the tank is almost empty. When the syringe is completely emptied, the control and motorization means as well as the intermediate piece can be recovered and reused on another syringe. On the other hand, it is preferable to discard the syringe piston assembly with its mechanical aggregate.
  • the piston with its aggregate will therefore preferably be made with synthetic materials so that the price is acceptable, with the exception of the lead screw itself which could be made of metal for reasons that we will see later.
  • FIG 4 shows by way of example a pull tab 40 for moving the piston before commissioning. It has been said that this zipper is removable.
  • this pull tab 40 has a clamp-shaped end 41 which can be opened by means of a rod 42 placed in the center of the pull rod 40.
  • This rod 42 has a conical end 43. By pressing on this rod 42, the conical end 43 opens the clamp 41 which allows the puller 40 to be released.
  • the clamp 41 is connected directly to the transmission wheel 44 which drives the lead screw, these two parts being preferably metallic so as to provide sufficient tensile strength. It is thus possible by means of the pull tab 40 to move the piston assembly linearly to carry out the filling operations of the syringe.
  • FIG. 5 shows, by way of example, means for coding the type of syringe used.
  • the same control and motorization means could be mounted on syringes of different capacities using suitable intermediate parts. If this is the case, the same speed of rotation of these motorization means will produce different flow rates depending on the type of syringe used.
  • One of the most important parameters during infusion therapy is flow.
  • a useful solution to avoid errors and facilitate the programming of the control means consists in introducing a means of coding the plunger / syringe system used which can be read by said control means.
  • this coding is carried out by means of two pins 50 and 51 mounted on the intermediate part 52. These two pins collaborate with two contacts 53 and 54 of the control and motorization means. Depending on the length of the nipples, the corresponding contacts are open or closed. In the configuration shown the contact 53 is closed and the contact 54 open, which corresponds for example to a 10 cc syringe.
  • the two contacts form a 2-bit binary combination that can be read by the control circuit, and which allows the latter to differentiate 4 different types of plunger / syringe systems. To increase the number of possibilities, simply increase the number of contacts.
  • the representation of Figure 5 is schematic, because there are very numerous possibilities known to those skilled in the art for carrying out this kind of coding, with contacts, without contacts, and it is not necessary to go into all the details.
EP96919518A 1995-06-14 1996-06-11 Spritzenkolben mit lineargetriebe Withdrawn EP0851774A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH175195 1995-06-14
CH175195 1995-06-14
PCT/CH1996/000221 WO1997000091A1 (fr) 1995-06-14 1996-06-11 Piston de seringue avec transmission lineaire

Publications (1)

Publication Number Publication Date
EP0851774A1 true EP0851774A1 (de) 1998-07-08

Family

ID=4217713

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96919518A Withdrawn EP0851774A1 (de) 1995-06-14 1996-06-11 Spritzenkolben mit lineargetriebe

Country Status (2)

Country Link
EP (1) EP0851774A1 (de)
WO (1) WO1997000091A1 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11504481B2 (en) 2007-10-02 2022-11-22 West Pharma. Services IL, Ltd. Anti-rotation feature for infusion pump cartridge
US11672904B2 (en) 2016-01-21 2023-06-13 West Pharma. Services IL, Ltd. Needle insertion and retraction mechanism
US11724034B2 (en) 2015-10-09 2023-08-15 West Pharma. Services, IL, Ltd. Injector system
US11819666B2 (en) 2017-05-30 2023-11-21 West Pharma. Services IL, Ltd. Modular drive train for wearable injector

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DE59610766D1 (de) 1996-07-05 2003-11-13 Disetronic Licensing Ag Injektionsgerät zum injizieren von flüssigkeit
DE19717107B4 (de) 1997-04-23 2005-06-23 Disetronic Licensing Ag System aus Behältnis und Antriebsvorrichtung für einen Kolben, der in dem ein Medikamentfluid enthaltenden Behältnis gehalten ist
DE19723648C1 (de) 1997-06-05 1998-08-27 Disetronic Licensing Ag Vorrichtung zur dosierten Verabreichung einer Medikamentflüssigkeit
FR2770136B1 (fr) * 1997-10-27 2000-03-10 Njc Innovations Dispositif d'administration de substances therapeutiques a seringue motorisee
DE19840992A1 (de) 1998-09-08 2000-03-09 Disetronic Licensing Ag Drucküberwachung eines bei einer Infusion oder Injektion dosiert zu verabreichenden Produktfluids
WO2000015280A1 (fr) 1998-09-15 2000-03-23 Njc Innovations Dispositifs d'administration de substances therapeutiques a seringue motorisee
US6508788B2 (en) 2000-10-27 2003-01-21 Novo Nordisk A/S Medication delivery device with telescopic piston rod
WO2002034315A1 (en) * 2000-10-27 2002-05-02 Novo Nordisk A/S A medication delivery device with telescopic piston rod
JP4549079B2 (ja) 2004-03-05 2010-09-22 パナソニック株式会社 医療用投与器具
EP1974759A1 (de) * 2007-03-29 2008-10-01 Jürgen Schmidt-Evers Injektionsgerät, insbesondere Insulin-Pen
US9345836B2 (en) 2007-10-02 2016-05-24 Medimop Medical Projects Ltd. Disengagement resistant telescoping assembly and unidirectional method of assembly for such
US7967795B1 (en) 2010-01-19 2011-06-28 Lamodel Ltd. Cartridge interface assembly with driving plunger
US9656019B2 (en) 2007-10-02 2017-05-23 Medimop Medical Projects Ltd. Apparatuses for securing components of a drug delivery system during transport and methods of using same
US10420880B2 (en) 2007-10-02 2019-09-24 West Pharma. Services IL, Ltd. Key for securing components of a drug delivery system during assembly and/or transport and methods of using same
EP2140897B1 (de) * 2008-06-30 2011-05-25 Animas Corporation Antriebsmechanismus
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
CA2750470A1 (en) 2009-02-05 2010-08-12 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
AU2010210158B2 (en) * 2009-02-05 2014-09-25 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
CH700630A1 (de) * 2009-03-18 2010-09-30 Tecpharma Licensing Ag Verabreichungsvorrichtung mit hydraulischer Kraftübertragung.
US9339607B2 (en) 2009-03-31 2016-05-17 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
US10071196B2 (en) 2012-05-15 2018-09-11 West Pharma. Services IL, Ltd. Method for selectively powering a battery-operated drug-delivery device and device therefor
US10071198B2 (en) 2012-11-02 2018-09-11 West Pharma. Servicees IL, Ltd. Adhesive structure for medical device
JP4873061B2 (ja) * 2009-10-09 2012-02-08 パナソニック株式会社 医療用投与器具
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
EP2569031B1 (de) 2010-05-10 2017-10-11 Medimop Medical Projects Ltd. Genauer injektor für geringe volumen
USD702834S1 (en) 2011-03-22 2014-04-15 Medimop Medical Projects Ltd. Cartridge for use in injection device
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
CN102793966B (zh) * 2012-08-02 2014-04-16 联合质量实业有限公司 便携可编程自动给药装置
US9421323B2 (en) 2013-01-03 2016-08-23 Medimop Medical Projects Ltd. Door and doorstop for portable one use drug delivery apparatus
US9011164B2 (en) 2013-04-30 2015-04-21 Medimop Medical Projects Ltd. Clip contact for easy installation of printed circuit board PCB
CN104132038B (zh) * 2013-04-30 2018-03-27 麦迪莫普医疗工程有限公司 伸缩组件和组装伸缩螺纹件的方法
US20170007774A1 (en) * 2014-02-03 2017-01-12 Novo Nordisk A/S Telescopic Drive Arrangement
FR3017436B1 (fr) * 2014-02-07 2016-03-04 Ad Hoc Scient Dispositif de controle de la translation axiale d'un element coulissant par rapport a une structure porteuse
EP3107604A1 (de) * 2014-02-17 2016-12-28 Novo Nordisk A/S Teleskopische antriebsanordnung mit oldham-kupplung
EP3122401B1 (de) * 2014-03-28 2020-08-05 Repro-Med Systems, Inc. Kompakte mechanische pumpe
US10137254B2 (en) 2014-05-02 2018-11-27 Novo Nordisk A/S Telescopic drive arrangement for drug delivery device
US10293120B2 (en) 2015-04-10 2019-05-21 West Pharma. Services IL, Ltd. Redundant injection device status indication
US10149943B2 (en) 2015-05-29 2018-12-11 West Pharma. Services IL, Ltd. Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly
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US9987432B2 (en) 2015-09-22 2018-06-05 West Pharma. Services IL, Ltd. Rotation resistant friction adapter for plunger driver of drug delivery device
JP7017512B2 (ja) 2015-10-09 2022-02-08 ウェスト ファーマ サービシーズ イスラエル リミテッド 充填済流体容器の屈曲流体路型付属物
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Publication number Priority date Publication date Assignee Title
US11504481B2 (en) 2007-10-02 2022-11-22 West Pharma. Services IL, Ltd. Anti-rotation feature for infusion pump cartridge
US11590291B2 (en) 2007-10-02 2023-02-28 West Pharma. Services IL, Ltd. External drug pump
US11724034B2 (en) 2015-10-09 2023-08-15 West Pharma. Services, IL, Ltd. Injector system
US11759573B2 (en) 2015-10-09 2023-09-19 West Pharma. Services, IL, Ltd. Bent fluid path add on to a prefilled reservoir
US11672904B2 (en) 2016-01-21 2023-06-13 West Pharma. Services IL, Ltd. Needle insertion and retraction mechanism
US11819666B2 (en) 2017-05-30 2023-11-21 West Pharma. Services IL, Ltd. Modular drive train for wearable injector

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