EP0847285A2 - Hohlfaser-oxygenator - Google Patents

Hohlfaser-oxygenator

Info

Publication number
EP0847285A2
EP0847285A2 EP96930684A EP96930684A EP0847285A2 EP 0847285 A2 EP0847285 A2 EP 0847285A2 EP 96930684 A EP96930684 A EP 96930684A EP 96930684 A EP96930684 A EP 96930684A EP 0847285 A2 EP0847285 A2 EP 0847285A2
Authority
EP
European Patent Office
Prior art keywords
fibers
blood
chamber
hollow fiber
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96930684A
Other languages
English (en)
French (fr)
Inventor
José BISCEGLI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CPP Holding Representacoes Ltda
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of EP0847285A2 publication Critical patent/EP0847285A2/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • A61M1/1625—Dialyser of the outside perfusion type, i.e. blood flow outside hollow membrane fibres or tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1629—Constructional aspects thereof with integral heat exchanger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3623—Means for actively controlling temperature of blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/0231—Manufacturing thereof using supporting structures, e.g. filaments for weaving mats
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/033—Specific distribution of fibres within one potting or tube-sheet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/22—Cooling or heating elements
    • B01D2313/221—Heat exchangers

Definitions

  • US-3,422,008 discloses a hollow fiber blood oxygenator and a method for forming it, wherein hollow fibers are helically wound on the core in such a way that intermediate helical windings are reversed. Thus, successive layers have opposite winding sense with respect to the core axis.
  • the blood flow is radial.
  • the annular space is not substantially filled with the fibers.
  • the hollow fiber arrangement according to the first embodiment of the present invention cannot be obtained by rotating the core and winding the filaments from a continuous roll of filaments onto the core by reversing the feed direction of the filament at the top and bottom ends of the core, since this process for manufacturing the fiber mat is only applicable when the second plurality of the fibers are wound in the other sense with respect to the first plurality.
  • the circumferential angle differences of the first plurality of fibers and the second plurality of fibers differ by at least 5°.
  • strips of mats of single layers of fiber filaments are prepared by first arranging a layer of long parallel fibers substantial- ly equally spaced from each other which are then fixed in their position by a connecting element, preferably a cross thread which is a flexible small diameter monofilament.
  • the thread must be sufficiently flexible to be easily bent around the hollow fibers. Furthermore, it must have sufficient tensile strength and tension to fix the filaments in their posi- tion, like in known tissues of clothes. This monofilament allows a regular spacing between the short single fiber filaments.
  • a known hollow fiber filament filling may be applied in which the hollow fiber filaments extend inside the chamber between the first cap and the second cap.
  • the circumferential angle difference of the fiber filaments between the sealings is not restricted and the directional sense of the fibers is not restricted either.
  • a partitioning wall described below has to be provided in this embodiment.
  • the hollow fiber filaments have the arrangement described above for the first embodiment.
  • a partitioning wall is provided between the core wall and the outer wall in a spaced position therefrom, which extends from one sealing towards the other sealing, thus forming sections in the chamber.
  • the sections have a flow connec ⁇ tion in the vicinity of the other sealing.
  • the flow connection in the vicinity of the other sealing may be provided in several ways.
  • the partitioning wall may extend into the other sealing being sealed there and exhibiting apertures in the vicinity of this other sealing. Annular slits may be provided in this partitioning wall.
  • the whole partitioning wall may extend only to a distance from the other sealing thus leaving an annular space between the end of the partitioning wall and the sealing.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing & Machinery (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
EP96930684A 1995-09-01 1996-08-29 Hohlfaser-oxygenator Withdrawn EP0847285A2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19532365A DE19532365C2 (de) 1995-09-01 1995-09-01 Hohlfaseroxygenator
DE19532365 1995-09-01
PCT/US1996/014148 WO1997008933A2 (en) 1995-09-01 1996-08-29 Hollow fiber oxygenator

Publications (1)

Publication Number Publication Date
EP0847285A2 true EP0847285A2 (de) 1998-06-17

Family

ID=7771069

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96930684A Withdrawn EP0847285A2 (de) 1995-09-01 1996-08-29 Hohlfaser-oxygenator

Country Status (7)

Country Link
EP (1) EP0847285A2 (de)
JP (1) JP3878675B2 (de)
AU (1) AU714100B2 (de)
BR (1) BR9610126A (de)
DE (1) DE19532365C2 (de)
WO (1) WO1997008933A2 (de)
ZA (1) ZA967361B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9910313B1 (pt) 1998-05-08 2008-11-18 reservatàrio de sangue/permutador tÉrmico combinado.
JP4041254B2 (ja) 1999-12-15 2008-01-30 テルモ株式会社 中空糸膜型人工肺
JP5477034B2 (ja) * 2010-02-15 2014-04-23 ニプロ株式会社 熱交換器一体型人工肺
JP5418274B2 (ja) * 2010-02-15 2014-02-19 ニプロ株式会社 熱交換器および熱交換器一体型人工肺
WO2011099609A1 (ja) * 2010-02-15 2011-08-18 ニプロ株式会社 熱交換器および熱交換器一体型人工肺
JP5418275B2 (ja) * 2010-02-15 2014-02-19 ニプロ株式会社 熱交換器および熱交換器一体型人工肺
JP5844585B2 (ja) * 2011-09-15 2016-01-20 ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータ 変更された流路を有する血液処理ユニット
DE102016006013A1 (de) * 2016-05-18 2017-11-23 Xenios Ag System für die extrakorporale Membranoxygenierung mit einer Blutpumpe und einem Oxygenator
DE102016010398A1 (de) 2016-06-10 2017-12-14 Hemovent Gmbh Gas-Austausch-Einheit, Verfahren zum Herstellen einer Gas-Austausch-Einheit und Set mit einer Gas-Austausch-Einheit und einer Befeuchtungs- und Wärmevorrichtung
LU100759B1 (de) 2017-09-20 2019-07-17 Hemovent Gmbh Gas-Austausch-Einheit
IT202000025762A1 (it) * 2020-10-29 2022-04-29 Qura S R L Ossigenatore di fluidi organici

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422008A (en) * 1963-10-24 1969-01-14 Dow Chemical Co Wound hollow fiber permeability apparatus and process of making the same
BE793624A (fr) * 1972-01-10 1973-05-02 Baxter Laboratories Inc Dispositif pour le transfert de masses, presentant une membrane de diffision tubulaire enroulee
FR2231421B1 (de) * 1973-05-30 1976-05-07 Rhone Poulenc Ind
GB1481064A (en) * 1973-08-30 1977-07-27 Teijin Ltd Membrane apparatus for treating fluids
JPS50131395A (de) * 1974-04-04 1975-10-17
US4031012A (en) * 1975-09-17 1977-06-21 Gics Pharmaceuticals, Inc. Separatory apparatus
US4289623A (en) * 1975-11-05 1981-09-15 Extracorporeal Medical Specialties, Inc. Hollow fiber dialysis
DE2646358C2 (de) * 1976-10-14 1982-05-13 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG Apparatebau KG, 6380 Bad Homburg Hohlfaserdialysator
FR2374932A1 (fr) * 1976-12-24 1978-07-21 Rhone Poulenc Ind Appareil a fibres creuses, utilisable notamment comme rein artificiel
US4239729A (en) * 1978-06-06 1980-12-16 Terumo Corporation Oxygenator
AU565652B2 (en) * 1982-02-19 1987-09-24 Dow Chemical Company, The Hollow fibre oxygenator element
FR2525487B1 (de) * 1982-04-27 1988-04-22 Hospal Sodip
CA1267339A (en) * 1985-01-08 1990-04-03 Anthony Badolato Mass transfer device having a microporous, spirally wound hollow fiber membrane
US5217698A (en) * 1986-02-06 1993-06-08 Steris Corporation Office size instrument sterilization system
DE3803693A1 (de) * 1987-03-10 1988-09-22 Akzo Gmbh Mehrlagiger hohlfadenwickelkoerper
JPH01281125A (ja) * 1988-04-30 1989-11-13 Daikin Ind Ltd 膜式気体分離装置
JPH0779954B2 (ja) * 1988-08-25 1995-08-30 宇部興産株式会社 ガス分離膜モジュール
JP2792048B2 (ja) * 1988-10-07 1998-08-27 大日本インキ化学工業株式会社 中空糸型流体処理装置
US5217689A (en) * 1989-10-26 1993-06-08 Baxter International Inc. Blood oxygenation system
US5013437A (en) * 1989-10-30 1991-05-07 The Dow Chemical Company Hollow fiber membrane fluid separation device adapted for boreside feed which contains multiple concentric stages
DK168031B1 (da) * 1991-04-03 1994-01-24 Polystan Holding As Oxygenator med et ringformet mellemrum mellem et indre roer og en ydre roerformet kappe, hvilket mellemrum i det vaesentlige er udfyldt af en omkring det indre roer opviklet bane af hulfibre

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9708933A2 *

Also Published As

Publication number Publication date
DE19532365C2 (de) 1998-12-17
JP3878675B2 (ja) 2007-02-07
DE19532365A1 (de) 1997-03-06
AU714100B2 (en) 1999-12-16
JP2001507245A (ja) 2001-06-05
BR9610126A (pt) 1999-12-07
WO1997008933A2 (en) 1997-03-13
AU6964696A (en) 1997-03-27
WO1997008933A3 (en) 1997-06-05
ZA967361B (en) 1997-09-16

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