EP0781846A3 - Antigène de fusion de treponema palladium, essai d'anticorps anti-treponema palladium avec ces antigènes de fusion - Google Patents

Antigène de fusion de treponema palladium, essai d'anticorps anti-treponema palladium avec ces antigènes de fusion Download PDF

Info

Publication number
EP0781846A3
EP0781846A3 EP96402904A EP96402904A EP0781846A3 EP 0781846 A3 EP0781846 A3 EP 0781846A3 EP 96402904 A EP96402904 A EP 96402904A EP 96402904 A EP96402904 A EP 96402904A EP 0781846 A3 EP0781846 A3 EP 0781846A3
Authority
EP
European Patent Office
Prior art keywords
treponema pallidum
fused antigen
assay
antibodies
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP96402904A
Other languages
German (de)
English (en)
Other versions
EP0781846A2 (fr
EP0781846B1 (fr
Inventor
Nobuyuki Ise
Takeya Hori
Katsuya Fujimura
Tetsuji Tanimoto
Masahisa Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujirebio Inc filed Critical Fujirebio Inc
Publication of EP0781846A2 publication Critical patent/EP0781846A2/fr
Publication of EP0781846A3 publication Critical patent/EP0781846A3/fr
Application granted granted Critical
Publication of EP0781846B1 publication Critical patent/EP0781846B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP96402904A 1995-12-25 1996-12-26 Antigène de fusion de treponema palladium, essai d'anticorps anti-treponema palladium avec ces antigènes de fusion Expired - Lifetime EP0781846B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP350072/95 1995-12-25
JP35007295 1995-12-25
JP35007295 1995-12-25

Publications (3)

Publication Number Publication Date
EP0781846A2 EP0781846A2 (fr) 1997-07-02
EP0781846A3 true EP0781846A3 (fr) 1998-05-13
EP0781846B1 EP0781846B1 (fr) 2003-09-17

Family

ID=18408044

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96402904A Expired - Lifetime EP0781846B1 (fr) 1995-12-25 1996-12-26 Antigène de fusion de treponema palladium, essai d'anticorps anti-treponema palladium avec ces antigènes de fusion

Country Status (7)

Country Link
US (2) US6248331B1 (fr)
EP (1) EP0781846B1 (fr)
KR (1) KR100257574B1 (fr)
AT (1) ATE250128T1 (fr)
CA (1) CA2193870C (fr)
DE (1) DE69630008T2 (fr)
ES (1) ES2207671T3 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0985931A3 (fr) * 1998-09-04 2000-03-29 Becton Dickinson and Company Immunoessai utilisant un antigène recombinant pour la diagnose de syphilis
US20050153382A1 (en) * 2002-06-06 2005-07-14 Chengdu Kuachang Science And Technology Co., Ltd. Biochip kit comprising biochip based on antigen-antibody reactions, and its usage
JP5414972B2 (ja) * 2003-12-23 2014-02-12 バイオキット, エセ.アー. 病原体感染の検出のための組成物および方法
US20100003706A1 (en) * 2005-04-14 2010-01-07 Washington, University Of Syphilis diagnostic tests and kits
US20060234321A1 (en) * 2005-04-14 2006-10-19 University Of Washington Syphilis diagnostic tests and kits
CN101858916A (zh) * 2010-05-19 2010-10-13 厦门大学附属中山医院 梅毒特异性IgM抗体胶体金免疫层析检测试剂条及其制备方法
CN101858915A (zh) * 2010-05-19 2010-10-13 厦门大学附属中山医院 梅毒特异性IgG抗体胶体金免疫层析检测试剂条及其制备方法
EP2663642B1 (fr) 2011-01-13 2017-03-01 Ortho-Clinical Diagnostics, Inc. Antigène triplet treponema pallidum
EP2617731A1 (fr) * 2012-01-19 2013-07-24 Roche Diagnostics GmbH Antigènes TpN47 de Treponema pallidum immunoréactifs solubles
BR112017019236A2 (pt) 2015-03-10 2018-04-24 Bio Rad Laboratories kit, e, método para detectar a presença de anticorpos de sífilis em uma amostra
CN111116718A (zh) * 2020-02-17 2020-05-08 北京博生福生物技术有限责任公司 一种蛋白连接肽及其在改造tp重组抗原中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995004145A1 (fr) * 1993-07-30 1995-02-09 Yale University Nouveaux polypeptides b. burgdorferi
JPH0763365A (ja) * 1993-08-24 1995-03-07 Takenaka Komuten Co Ltd 大空間施設の気流発生装置
WO1995012676A1 (fr) * 1993-11-01 1995-05-11 Associated Universities, Inc. Proteines chimeres comprenant des polypeptides de borrelia et leurs utilisations
EP0670494A2 (fr) * 1994-02-28 1995-09-06 FUJIREBIO Inc. Essai immunologique d'anticorps anti-tréponèmes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59502131A (ja) 1982-11-12 1984-12-27 ザ リ−ジエンツ オブ ユニバ−シテイ オブ カリフオルニア 組換えdna誘導型梅毒トレポネ−マ抗原
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995004145A1 (fr) * 1993-07-30 1995-02-09 Yale University Nouveaux polypeptides b. burgdorferi
JPH0763365A (ja) * 1993-08-24 1995-03-07 Takenaka Komuten Co Ltd 大空間施設の気流発生装置
WO1995012676A1 (fr) * 1993-11-01 1995-05-11 Associated Universities, Inc. Proteines chimeres comprenant des polypeptides de borrelia et leurs utilisations
EP0670494A2 (fr) * 1994-02-28 1995-09-06 FUJIREBIO Inc. Essai immunologique d'anticorps anti-tréponèmes

Also Published As

Publication number Publication date
DE69630008D1 (de) 2003-10-23
KR970048455A (ko) 1997-07-29
US20010002311A1 (en) 2001-05-31
CA2193870A1 (fr) 1997-06-26
KR100257574B1 (ko) 2000-08-01
US6794155B2 (en) 2004-09-21
ES2207671T3 (es) 2004-06-01
EP0781846A2 (fr) 1997-07-02
ATE250128T1 (de) 2003-10-15
DE69630008T2 (de) 2004-07-08
CA2193870C (fr) 2000-07-18
EP0781846B1 (fr) 2003-09-17
US6248331B1 (en) 2001-06-19

Similar Documents

Publication Publication Date Title
AU1520895A (en) Purified primate ctla-8 antigens and related reagents
AU8432498A (en) Human-cd28 specific monoclonal antibodies for antigen non-specific activation oft-lymphocytes
AU5869596A (en) Anti-gp130 monoclonal antibodies
AU4042195A (en) Anti-alphaV-integrin monoclonal antibody
AU4752696A (en) Monoclonal antibodies for human osteogenic cell surface antigens
EP2270047A3 (fr) Anticorps contre C5 et leurs utilisations thérapeutiques
AU3407197A (en) Purified sperm surface antigen, monoclonal antibody therefor and applications therefor
EP0842948A4 (fr) ANTICORPS DE LIGAND ANTIFas ET PROCEDE D'EPREUVE LE FAISANT INTERVENIR
EP0781846A3 (fr) Antigène de fusion de treponema palladium, essai d'anticorps anti-treponema palladium avec ces antigènes de fusion
AU2645297A (en) Hepatitis b monoclonal antibodies
AU2477792A (en) Monoclonal antibody specific for an antigen on dendritic cells
AU6220096A (en) Method for the simultaneous detection of different antibodies and/or antigens
AU6031090A (en) Monoclonal antibodies against a tumor-associated antigen
AU1423892A (en) Monoclonal antibodies directed towards mycobacterial antigens
AU7068587A (en) Monoclonal antibody immunoblot assay for antigens
AU2696495A (en) Method for determining hiv-1 antigen and antibody
AU2547995A (en) Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1, the antigen itself, and uses thereof
EP0670494A3 (fr) Essai immunologique d'anticorps anti-tréponèmes.
AU9052491A (en) Assay device and method for antibody and antigen detection
AU1437695A (en) Monoclonal antibodies against hev orf-2 and methods for using same
AU2759899A (en) Purified sperm surface antigen, monoclonal antibody therefor and application therefor
GB9710875D0 (en) Assay for detecting HIV antigens and HIV antibodies
AU687932B2 (en) A method for the determinatin of antigens or antibodies in the presence of an immune complex
EP0629857A3 (fr) Immunoessai pour la determination quantitative d'antigènes.
AU2412692A (en) Novel peptide antigens and immunoassays, test kits and vaccines using the same

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

17P Request for examination filed

Effective date: 19981102

17Q First examination report despatched

Effective date: 20020320

GRAH Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOS IGRA

RIN1 Information on inventor provided before grant (corrected)

Inventor name: OKADA, MASAHISA

Inventor name: TANIMOTO, TETSUJI

Inventor name: FUJIMURA, KATSUYA

Inventor name: HORI, TAKEYA

Inventor name: ISE, NOBUYUKI

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20030917

Ref country code: LI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20030917

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20030917

Ref country code: CH

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20030917

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20030917

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20030917

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REF Corresponds to:

Ref document number: 69630008

Country of ref document: DE

Date of ref document: 20031023

Kind code of ref document: P

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20031217

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20031217

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20031217

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20031226

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20031226

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20031230

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20031231

NLV1 Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act
REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2207671

Country of ref document: ES

Kind code of ref document: T3

ET Fr: translation filed
PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20040618

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

REG Reference to a national code

Ref country code: GB

Ref legal event code: 732E

REG Reference to a national code

Ref country code: FR

Ref legal event code: TP

Ref country code: FR

Ref legal event code: CD

REG Reference to a national code

Ref country code: FR

Ref legal event code: CA

Effective date: 20130719

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20151223

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20151112

Year of fee payment: 20

Ref country code: FR

Payment date: 20151110

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20151222

Year of fee payment: 20

Ref country code: IT

Payment date: 20151221

Year of fee payment: 20

REG Reference to a national code

Ref country code: DE

Ref legal event code: R071

Ref document number: 69630008

Country of ref document: DE

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Expiry date: 20161225

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20161225

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20161227