EP0743981A4 - Hoch auflösender zellkultur-bioreaktor und seine verwendung - Google Patents

Hoch auflösender zellkultur-bioreaktor und seine verwendung

Info

Publication number
EP0743981A4
EP0743981A4 EP94915758A EP94915758A EP0743981A4 EP 0743981 A4 EP0743981 A4 EP 0743981A4 EP 94915758 A EP94915758 A EP 94915758A EP 94915758 A EP94915758 A EP 94915758A EP 0743981 A4 EP0743981 A4 EP 0743981A4
Authority
EP
European Patent Office
Prior art keywords
cell culture
high performance
culture bioreactor
performance cell
bioreactor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94915758A
Other languages
English (en)
French (fr)
Other versions
EP0743981A1 (de
Inventor
Randal A Goffe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genespan Corp
Original Assignee
UniSyn Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UniSyn Technologies Inc filed Critical UniSyn Technologies Inc
Publication of EP0743981A1 publication Critical patent/EP0743981A1/de
Publication of EP0743981A4 publication Critical patent/EP0743981A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
EP94915758A 1994-02-09 1994-02-09 Hoch auflösender zellkultur-bioreaktor und seine verwendung Withdrawn EP0743981A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/002140 WO1995021911A1 (en) 1994-02-09 1994-02-09 High performance cell culture bioreactor and method

Publications (2)

Publication Number Publication Date
EP0743981A1 EP0743981A1 (de) 1996-11-27
EP0743981A4 true EP0743981A4 (de) 1999-09-08

Family

ID=22242305

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94915758A Withdrawn EP0743981A4 (de) 1994-02-09 1994-02-09 Hoch auflösender zellkultur-bioreaktor und seine verwendung

Country Status (4)

Country Link
EP (1) EP0743981A4 (de)
JP (1) JPH09511392A (de)
AU (1) AU687059B2 (de)
WO (1) WO1995021911A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622857A (en) * 1995-08-08 1997-04-22 Genespan Corporation High performance cell culture bioreactor and method
US5882918A (en) * 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
US6680166B1 (en) * 1995-06-07 2004-01-20 Claudy Jean Paul Mullon Dual fiber bioreactor
WO1996041810A1 (en) * 1995-06-08 1996-12-27 Progen Industries Limited Method and apparatus for dna extraction
WO1997012960A2 (en) * 1995-10-06 1997-04-10 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Solid support for use in cell cultivation, especially for the cultivation of liver cells, biological reactor containing said solid support and the use thereof in a bio-artificial liver system
US5993406A (en) * 1997-05-14 1999-11-30 Cedars-Sinai Medical Center Artificial gut
US6027937A (en) * 1998-08-18 2000-02-22 Harper; William Method for propagation of insecta germ cells
CN1316014C (zh) * 2004-04-09 2007-05-16 华东理工大学 骨髓间充质干细胞的规模化制备方法
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
CA2680130C (en) 2007-03-05 2016-01-12 Caridianbct, Inc. Cell expansion system and methods of use
EP2148922B1 (de) 2007-04-13 2020-03-04 Terumo BCT, Inc. Zellexpansionssystem und verfahren zu seiner verwendung
US9057045B2 (en) 2009-12-29 2015-06-16 Terumo Bct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
WO2011140231A1 (en) 2010-05-05 2011-11-10 Caridianbct, Inc. Method of reseeding adherent cells grown in a hollow fiber bioreactor system
EP2625264B1 (de) 2010-10-08 2022-12-07 Terumo BCT, Inc. Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen
DK2718416T3 (da) 2011-06-06 2020-02-24 ReGenesys BVBA Ekspansion af stamceller i hulfiberbioreaktorer
CA2863795A1 (en) 2012-02-13 2013-08-22 Gamida-Cell Ltd. Culturing of mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
CN104540933A (zh) 2012-08-20 2015-04-22 泰尔茂比司特公司 在细胞扩增系统的生物反应器中加载和分配细胞的方法
JP2014117190A (ja) * 2012-12-13 2014-06-30 Mitsubishi Rayon Co Ltd 浮遊細胞培養のための装置、モジュール及び方法
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2015164808A1 (en) 2014-04-24 2015-10-29 Terumo Bct, Inc. Measuring flow rate
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (de) 2016-05-25 2020-01-01 Terumo BCT, Inc. Zellexpansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63240774A (ja) * 1987-03-27 1988-10-06 Ube Ind Ltd バイオリアクタ−
JPS63317075A (ja) * 1987-06-19 1988-12-26 Nok Corp バブリング式バイオリアクタ−
JPH01222768A (ja) * 1988-03-01 1989-09-06 Ube Ind Ltd バイオリアクター

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061736A (en) * 1975-02-02 1977-12-06 Alza Corporation Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin
US4220725A (en) * 1978-04-03 1980-09-02 United States Of America Capillary cell culture device
FR2580514B1 (fr) * 1985-04-17 1989-08-18 Lyonnaise Eaux Ensemble composite de membranes de filtration et son utilisation dans un bioreacteur
US4720462A (en) * 1985-11-05 1988-01-19 Robert Rosenson Culture system for the culture of solid tissue masses and method of using the same
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
GB8921458D0 (en) * 1989-09-22 1989-11-08 Univ Strathclyde Cell culture apparatus
US5278063A (en) * 1989-09-28 1994-01-11 Board Of Regents The University Of Texas System Chemical modification of promote animal cell adhesion on surfaces

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63240774A (ja) * 1987-03-27 1988-10-06 Ube Ind Ltd バイオリアクタ−
JPS63317075A (ja) * 1987-06-19 1988-12-26 Nok Corp バブリング式バイオリアクタ−
JPH01222768A (ja) * 1988-03-01 1989-09-06 Ube Ind Ltd バイオリアクター

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 013, no. 042 (C - 564) 30 January 1989 (1989-01-30) *
PATENT ABSTRACTS OF JAPAN vol. 013, no. 169 (C - 587) 21 April 1989 (1989-04-21) *
PATENT ABSTRACTS OF JAPAN vol. 013, no. 546 (C - 661) 6 December 1989 (1989-12-06) *
See also references of WO9521911A1 *

Also Published As

Publication number Publication date
AU687059B2 (en) 1998-02-19
WO1995021911A1 (en) 1995-08-17
AU6765594A (en) 1995-08-29
JPH09511392A (ja) 1997-11-18
EP0743981A1 (de) 1996-11-27

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