EP0729345A1 - Combinaisons de substances actives desodorisantes a base d'acides alpha-omega-alcanedicarboxyliques et de glycerides partiels d'acides gras - Google Patents
Combinaisons de substances actives desodorisantes a base d'acides alpha-omega-alcanedicarboxyliques et de glycerides partiels d'acides grasInfo
- Publication number
- EP0729345A1 EP0729345A1 EP95900064A EP95900064A EP0729345A1 EP 0729345 A1 EP0729345 A1 EP 0729345A1 EP 95900064 A EP95900064 A EP 95900064A EP 95900064 A EP95900064 A EP 95900064A EP 0729345 A1 EP0729345 A1 EP 0729345A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- acid
- partial glycerides
- acids
- cosmetic deodorants
- cosmetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/05—Stick
Definitions
- Deodorant active ingredient combinations based on alpha-omega-alkanedicarboxylic acids and fatty acid partial glycerides
- the present invention relates to cosmetic active ingredient combinations, in particular active ingredient combinations as an effective principle in cosmetic deodorants.
- Cosmetic deodorants serve to eliminate body odor which arises when the fresh, odorless sweat is decomposed by microorganisms.
- the usual cosmetic deodorants are based on different active principles.
- astringents primarily aluminum salts such as aluminum hydroxychloride (aluminum chlorohydrate) - can prevent the formation of sweat.
- aluminum salts such as aluminum hydroxychloride (aluminum chlorohydrate)
- the substances used for this depending on their dosage, have a drastic effect on the heat balance of the armpit region and should only be used in exceptional cases.
- the sweat flow itself is not affected by this, in the ideal case only the microbial decomposition of the sweat is temporarily stopped.
- body odor can also be covered by fragrances, a method that least meets the aesthetic needs of the consumer, since the mixture of body odor and perfume smells rather unpleasant.
- Perfuming cosmetic preparations containing active ingredients is not infrequently problematic because active ingredients and perfume components can occasionally react with one another and render them ineffective.
- Deodorants should meet the following conditions:
- liquid deodorants for example aerosol sprays, roll-ons and the like
- solid preparations for example deodorant sticks ("sticks"), powder, powder sprays, intimate cleansing agents, etc.
- the object of the present invention was therefore to develop cosmetic deodorants which do not have the disadvantages of the prior art.
- the deodorants should largely protect the microflora of the skin, but selectively reduce the number of microorganisms which are responsible for body odor.
- a further task was to develop cosmetic deodorants which harmonize with the largest possible number of customary cosmetic auxiliaries and additives, in particular those which are deodorising or antiperspirant. formulations of significant perfume ingredients with a pirating effect.
- a further object of the invention was to provide cosmetic deodorants which are effective over a longer period of time, on the order of at least half a day, without their action noticeably diminishing.
- EP-0 036 134 describes deodorising compositions, characterized by a content of derivatives of medium- to long-chain alkanoic acids, which also include the ⁇ , ⁇ -alkanedicarboxylic acids of the general formula
- German Offenlegungsschrift DE-OS 27 03 642 describes deodorising agents for personal hygiene, which include, among other things, certain ⁇ , ⁇ -alkanedicarboxylic acids, but there is no reference to the teaching presented here in this document either.
- the ⁇ , ⁇ -alkanedicarboxylic acids are preferably selected from the group of substances which are of the generic formula
- n can take numbers from 1 to 8.
- the di- or triglycerol units of the partial glycerides according to the invention are present as linear, unbranched molecules, ie "monoglycerol molecules” etherified via the respective OH groups in the 1- or 3-position.
- a small proportion of cyclic di- or triglycerol units and glycerol molecules etherified via the OH groups in the 2-position can be tolerated. However, it is advantageous to keep such impurities as low as possible.
- R ' represents an unbranched alkyl radical of 5 to 17 carbon atoms.
- H2Ct-C H-CH2 "-0-CH2-CiH-CH2-O-CH. • CH-CH-,
- R represents an unbranched alkyl radical of 5 to 17 carbon atoms.
- the fatty acids or monocarboxylic acids on which these esters are based are the
- esters of diglycerol are preferred to those of triglycerol according to the invention.
- TML Triglycerol Monolaurate
- TMS Triglycerol Monomyristate
- Diglycerol monocaprinate has proven to be the preferred partial glyceride according to the invention. Partial glycerides based on such monocarboxylic acid esters, which are obtainable by a process as described in DE-OS 38 18 293, are particularly advantageous.
- mixtures of one or more monocarboxylic acid esters of diglycerol with one or more monocarboxylic acid esters of triglycerol are used as partial glycerides of unbranched fatty acids.
- one or more monocarboxylic acid esters of diglycerol and / or one or more monocarboxylic acid esters of triglycerol in combination with other active substances (substitute active substances) customary in cosmetics are used as partial glycerides of unbranched fatty acids, auxiliary substances , Blending and / or additives used.
- the blends and / or replacement active ingredients are then advantageously present in a concentration of up to 50 parts by weight, preferably up to 35 parts by weight, based on the 100 parts by weight of the total amount resulting from the monocarboxylic acid ester or the monocarboxylic acid esters of diglycerol and / or triglycerol and these substitute active ingredients and / or blends.
- a method for combating human body odor caused by microbial decomposition of apocrine sweat is further characterized in that an effective amount of
- a suitable cosmetic carrier for controlling gram-positive, in particular coryneform bacteria, or the use of mixtures of
- the cosmetic deodorants according to the invention are particularly advantageously characterized in that the ⁇ , ⁇ -alkanedicarboxylic acids are present in concentrations of 0.05-10.00 % By weight, preferably 0.1-5.0% by weight, are present, in each case based on the total weight of the preparations.
- the cosmetic deodorants according to the invention are also particularly advantageously characterized in that the fatty acid partial glycerides of unbranched fatty acids are present in concentrations of 0.05-10.00% by weight, preferably 0.1-5.0% by weight, based in each case on the Total weight of the preparations.
- the cosmetic deodorants according to the invention can be in the form of aerosols, that is to say from aerosol containers, squeeze bottles or preparations which can be sprayed by a pump device, or in the form of liquid compositions which can be applied by means of roll-on devices, as deodorant sticks (deodorant sticks). Sticks) and in the form of W / 0 or O / W emulsions that can be applied from normal bottles and containers, e.g. Creams or lotions.
- the cosmetic deodorants can advantageously be in the form of deodorizing tinctures, deodorizing intimate cleansing agents, deodorizing shampoos, deodorising shower or bath preparations, deodorising powders or deodorising powder sprays.
- ethanol and isopropanol, glycerol and propylene glycol, skin-caring fat or fat-like substances, such as oleic acid decyl ester, cetyl alcohol, cetylstearyl alcohol and 2-0ctyldodecanol, can be used as customary cosmetic carriers for the production of the deodorant preparations according to the invention in the quantitative amounts customary for such preparations ⁇ ratios are used as well as slime-forming substances and thickeners, such as hydroxyethyl or hydroxypropyl cellulose, polyvinyl pyrrolidone, but also in small quantities cyclic silicone oils (polydimethylsiloxanes) and liquid polymethylphenylsiloxanes of low viscosity.
- Suitable blowing agents for cosmetic deodorants according to the invention which can be sprayed from aerosol containers are the customary, known volatile, liquefied blowing agents, for example hydrocarbons (propane, butane, isobutane), which can be used alone or in a mixture with one another. Compressed air can also be used advantageously.
- hydrocarbons propane, butane, isobutane
- emulsifiers for the production of the cosmetic deodorants according to the invention which should advantageously be applied as liquid preparations to the desired skin areas by means of a roll-on device, and which are present in the preparations in small amounts, for example 2 to 5 Ge wichts.- 0 ⁇ , based on the total composition, can be used non-ionic types, such as polyoxyethylene fatty alcohol ethers, for example cetostearyl alcohol polyethylene glycol ethers with 12 or 20 added ethylene oxide units per molecule, cetostearyl alcohol and sorbitan esters and sorbitan esters -Ethylene oxide compounds (eg sorbitan monostearate and polyoxyethylene sorbitan onostearate) and long-chain, higher molecular weight waxy polyglycol ethers have been found to be suitable.
- non-ionic types such as polyoxyethylene fatty alcohol ethers, for example cetostearyl alcohol polyethylene glycol ethers with 12 or 20 added ethylene oxide units per molecule, ce
- BHT butylated hydroxytoluene
- the pH of the preparations according to the invention is particularly advantageously selected in the range from 4.5 to 6.5, in particular around 5.5.
- the amount of cosmetic carrier and perfume to be used in each case can easily be determined by a person skilled in the art depending on the type of product in question by simply trying it out.
- the cosmetic preparations are produced in a customary manner, usually simply by mixing with stirring, if appropriate with gentle heating. It offers no difficulties.
- fat phase and water phase e.g. prepared separately, optionally with heating and then emulsified.
- the suspension bases for this can advantageously be selected from the group Silica gels (e.g. those sold under the trade name
- Aerosil are available), diatomaceous earth, talc, modified starch, titanium dioxide, silk powder, nylon powder, polyethylene powder and related substances.
- the components under a) are heated with stirring until the mixture is melted clear.
- Mixture b) is prepared after the required amount of NaOH solution has been determined in order to obtain a pH of about 5.5 in the finished product. Examples 5-8
- Mixture c) is prepared after preliminary determination of the required amount of NaOH solution in order to obtain a pH of about 5.5 in the finished product and added to a). The mixture is allowed to swell at room temperature, a solution of the below (b) mentioned components are added after about 15 minutes. The resulting mixture is homogenized and can be filled.
- a solution is prepared from the components b), which is heated to 35 ° C. and added to the mixture of a) and c) with stirring.
- Glyceryl stearate self-emitting 10.00 1 0,. 00
- the ingredients are melted at approx. 75 ° C, mixed well and poured into suitable molds.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
Désodorisants cosmétiques contenant des mélanges I) d'acides α, Φ-alcanedicarboxyliques et II) de glycérides partiels d'acides gras non ramifiés.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4339605 | 1993-11-20 | ||
DE4339605A DE4339605A1 (de) | 1993-11-20 | 1993-11-20 | Desodorierende Wirkstoffkombinationen auf der Basis von alpha, omega-Alkandicarbonsäuren und Fettsäurepartialglyceriden |
PCT/DE1994/001303 WO1995014458A1 (fr) | 1993-11-20 | 1994-11-05 | Combinaisons de substances actives desodorisantes a base d'acides alpha-omega-alcanedicarboxyliques et de glycerides partiels d'acides gras |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0729345A1 true EP0729345A1 (fr) | 1996-09-04 |
Family
ID=6503042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95900064A Ceased EP0729345A1 (fr) | 1993-11-20 | 1994-11-05 | Combinaisons de substances actives desodorisantes a base d'acides alpha-omega-alcanedicarboxyliques et de glycerides partiels d'acides gras |
Country Status (5)
Country | Link |
---|---|
US (1) | US5780019A (fr) |
EP (1) | EP0729345A1 (fr) |
JP (1) | JPH09505311A (fr) |
DE (1) | DE4339605A1 (fr) |
WO (1) | WO1995014458A1 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1000681C2 (nl) * | 1995-06-28 | 1996-12-31 | Suiker Unie | Deo-samenstelling. |
DE19543696A1 (de) * | 1995-11-23 | 1997-05-28 | Beiersdorf Ag | Gegen Bakterien, Mycota und Viren wirksame Wirkstoffkombinationen auf der Basis von Partialglyceriden und dialkylsubstituierte Essigsäuren |
US6458574B1 (en) | 1996-09-12 | 2002-10-01 | Transkaryotic Therapies, Inc. | Treatment of a α-galactosidase a deficiency |
DE59913680D1 (de) * | 1998-05-15 | 2006-08-31 | Goldschmidt Gmbh | Fettsäurepartialester von Polyolen |
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
WO2001007002A1 (fr) * | 1999-07-26 | 2001-02-01 | Kao Corporation | Desodorisants |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
JP2002299602A (ja) * | 2001-03-28 | 2002-10-11 | Mitsubishi Heavy Ind Ltd | バイポーラトランジスタ |
ES2367257T3 (es) | 2002-04-25 | 2011-10-31 | Shire Human Genetic Therapies, Inc. | Tratamiento de deficit de alfa-galactosidasa a. |
JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
CA2864810A1 (fr) | 2003-04-18 | 2004-11-04 | Biogen Idec Ma, Inc. | Neublastine a conjugaison polymere glycosylee |
NZ553420A (en) | 2004-08-19 | 2010-02-26 | Biogen Idec Inc | Refolding transforming growth factor beta family proteins |
EP2238983B1 (fr) * | 2004-08-19 | 2014-07-23 | Biogen Idec MA Inc. | Variantes de la neuroblastine |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
ES2450065T3 (es) * | 2006-03-01 | 2014-03-21 | Biogen Idec Ma Inc. | Composiciones y métodos para la administración de proteínas de la familia de ligandos del GDNF |
US8329655B2 (en) * | 2007-05-01 | 2012-12-11 | Biogen Idec Ma Inc. | Methods for increasing vascularization |
WO2009020964A2 (fr) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anticorps anti-neublastine et leurs utilisations |
DE102010022064A1 (de) * | 2010-05-31 | 2011-12-01 | Beiersdorf Ag | Deodorant- oder Antitranspirantzubereitung mit Polyolpartialester |
NL2017294B1 (en) | 2016-08-05 | 2018-02-14 | Univ Erasmus Med Ct Rotterdam | Natural cryptic exon removal by pairs of antisense oligonucleotides. |
EP4153123A1 (fr) * | 2020-05-20 | 2023-03-29 | Unilever IP Holdings B.V. | Compositions et méthodes permettant d'apporter des bénéfices pour le soin du cuir chevelu |
WO2021234055A1 (fr) * | 2020-05-20 | 2021-11-25 | Unilever Ip Holdings B.V. | Compositions et méthodes pour fournir des bénéfices pour le soin de la peau |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4089942A (en) * | 1976-01-29 | 1978-05-16 | L'oreal | Deodorant composition and process |
US4725431A (en) * | 1984-06-15 | 1988-02-16 | American Cyanamid Company | Method for the preparation of water-in-oil emulsion antiperspirants |
JPS61143317A (ja) * | 1984-12-15 | 1986-07-01 | Sunstar Inc | 抗微生物剤組成物 |
DE3818293C2 (de) * | 1988-05-30 | 1997-05-07 | Solvay Werke Gmbh | Verfahren zur Herstellung von nichtionogenen Tensiden, deren Verwendung sowie Zubereitungen unter Verwendung derselben |
FR2655542B1 (fr) * | 1989-12-13 | 1994-02-11 | Oreal | Composition cosmetique pour application topique contenant des huiles essentielles. |
-
1993
- 1993-11-20 DE DE4339605A patent/DE4339605A1/de not_active Ceased
-
1994
- 1994-11-05 US US08/640,881 patent/US5780019A/en not_active Expired - Fee Related
- 1994-11-05 EP EP95900064A patent/EP0729345A1/fr not_active Ceased
- 1994-11-05 WO PCT/DE1994/001303 patent/WO1995014458A1/fr not_active Application Discontinuation
- 1994-11-05 JP JP7514732A patent/JPH09505311A/ja active Pending
Non-Patent Citations (1)
Title |
---|
See references of WO9514458A1 * |
Also Published As
Publication number | Publication date |
---|---|
US5780019A (en) | 1998-07-14 |
DE4339605A1 (de) | 1995-05-24 |
JPH09505311A (ja) | 1997-05-27 |
WO1995014458A1 (fr) | 1995-06-01 |
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Legal Events
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