EP0711160A4 - Procede d'inhibition de la replication des virus de l'immunodeficience humaine a l'aide d'azaspirannes substitues - Google Patents
Procede d'inhibition de la replication des virus de l'immunodeficience humaine a l'aide d'azaspirannes substituesInfo
- Publication number
- EP0711160A4 EP0711160A4 EP94922685A EP94922685A EP0711160A4 EP 0711160 A4 EP0711160 A4 EP 0711160A4 EP 94922685 A EP94922685 A EP 94922685A EP 94922685 A EP94922685 A EP 94922685A EP 0711160 A4 EP0711160 A4 EP 0711160A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- replication
- inhibiting
- human immunodeficiency
- immunodeficiency viruses
- azaspiranes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9315340 | 1993-07-23 | ||
GB939315340A GB9315340D0 (en) | 1993-07-23 | 1993-07-23 | Methods |
PCT/US1994/008276 WO1995003042A1 (fr) | 1993-07-23 | 1994-07-22 | Procede d'inhibition de la replication des virus de l'immunodeficience humaine a l'aide d'azaspirannes substitues |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0711160A1 EP0711160A1 (fr) | 1996-05-15 |
EP0711160A4 true EP0711160A4 (fr) | 1998-09-09 |
Family
ID=10739357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94922685A Withdrawn EP0711160A4 (fr) | 1993-07-23 | 1994-07-22 | Procede d'inhibition de la replication des virus de l'immunodeficience humaine a l'aide d'azaspirannes substitues |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0711160A4 (fr) |
JP (1) | JPH09500648A (fr) |
CN (1) | CN1130871A (fr) |
AU (1) | AU7370994A (fr) |
CA (1) | CA2167842A1 (fr) |
GB (1) | GB9315340D0 (fr) |
NZ (1) | NZ269991A (fr) |
WO (1) | WO1995003042A1 (fr) |
ZA (1) | ZA945418B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9315351D0 (en) * | 1993-07-23 | 1993-09-08 | Smithkline Beecham Corp | Methods |
GB9315306D0 (en) * | 1993-07-23 | 1993-09-08 | Smithkline Beecham Corp | Methods |
BR9601909A (pt) * | 1995-07-13 | 1999-10-13 | Smithkline Beecham Corp | N,n-dietil-8,8-dipropil-2-azaspiro(4,5)decano-2-propan amina dimaleato |
CZ367598A3 (cs) * | 1996-05-17 | 1999-05-12 | Anormed Inc. | Použití substituovaného azaspiranu |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992014462A1 (fr) * | 1991-02-19 | 1992-09-03 | Smithkline Beecham Corporation | Inhibiteurs de cytokines |
WO1993014760A2 (fr) * | 1992-01-28 | 1993-08-05 | Smithkline Beecham Corporation | Procedes |
WO1993015735A1 (fr) * | 1992-01-28 | 1993-08-19 | Smithkline Beecham Corporation | Procede (non descriptif) de retardement du sida chez des sujets contamines par le vih par administration de composes d'azaspirane substitue |
WO1995003048A1 (fr) * | 1993-07-23 | 1995-02-02 | Smithkline Beecham Corporation | Azaspiranes anti-hiv |
WO1995003049A1 (fr) * | 1993-07-23 | 1995-02-02 | Smithkline Beecham Corporation | Procedes de traitement du vih au moyen d'azaspiranes |
WO1995003041A1 (fr) * | 1993-07-23 | 1995-02-02 | Smithkline Beecham Corporation | Procede d'inhibition de la production de virus de l'immunodeficience chez l'homme au moyen d'azaspiranes substitues |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963557A (en) * | 1987-09-28 | 1990-10-16 | Smithkline Beecham Corporation | Immunomodulatory azaspiranes |
-
1993
- 1993-07-23 GB GB939315340A patent/GB9315340D0/en active Pending
-
1994
- 1994-07-22 CA CA002167842A patent/CA2167842A1/fr not_active Abandoned
- 1994-07-22 CN CN94193381A patent/CN1130871A/zh active Pending
- 1994-07-22 JP JP7505332A patent/JPH09500648A/ja not_active Ceased
- 1994-07-22 WO PCT/US1994/008276 patent/WO1995003042A1/fr not_active Application Discontinuation
- 1994-07-22 EP EP94922685A patent/EP0711160A4/fr not_active Withdrawn
- 1994-07-22 ZA ZA945418A patent/ZA945418B/xx unknown
- 1994-07-22 AU AU73709/94A patent/AU7370994A/en not_active Abandoned
- 1994-07-22 NZ NZ269991A patent/NZ269991A/xx unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992014462A1 (fr) * | 1991-02-19 | 1992-09-03 | Smithkline Beecham Corporation | Inhibiteurs de cytokines |
WO1993014760A2 (fr) * | 1992-01-28 | 1993-08-05 | Smithkline Beecham Corporation | Procedes |
WO1993015735A1 (fr) * | 1992-01-28 | 1993-08-19 | Smithkline Beecham Corporation | Procede (non descriptif) de retardement du sida chez des sujets contamines par le vih par administration de composes d'azaspirane substitue |
WO1995003048A1 (fr) * | 1993-07-23 | 1995-02-02 | Smithkline Beecham Corporation | Azaspiranes anti-hiv |
WO1995003049A1 (fr) * | 1993-07-23 | 1995-02-02 | Smithkline Beecham Corporation | Procedes de traitement du vih au moyen d'azaspiranes |
WO1995003041A1 (fr) * | 1993-07-23 | 1995-02-02 | Smithkline Beecham Corporation | Procede d'inhibition de la production de virus de l'immunodeficience chez l'homme au moyen d'azaspiranes substitues |
Non-Patent Citations (4)
Title |
---|
BADGER A M ET AL: "ANTIARTHRITIC AND SUPPRESSOR CELL INDUCING ACTIVITY OF AZASPIRANES:STRUCTURE-FUNCTION RELATIONSHIPS OF A NOVEL CLASS OF IMMUNOMODULATORY AGENTS", JOURNAL OF MEDICINAL CHEMISTRY, vol. 33, no. 11, November 1990 (1990-11-01), pages 2963 - 2970, XP000605424 * |
P.S. SARIN ET AL.: "INHIBITION OF HTLV-III REPLICATION IN CELL CULTURES", NATO ASI SER., SER. A, vol. 120, 1986, pages 329 - 42, XP002069579 * |
S. GOODMAN: "THERAPEUTIC EFFECTS OF ORGANIC GERMANIUM", MEDICAL HYPOTHESES, vol. 26, 1988, pages 207 - 215, XP002069578 * |
See also references of WO9503042A1 * |
Also Published As
Publication number | Publication date |
---|---|
ZA945418B (en) | 1995-05-10 |
WO1995003042A1 (fr) | 1995-02-02 |
CN1130871A (zh) | 1996-09-11 |
JPH09500648A (ja) | 1997-01-21 |
GB9315340D0 (en) | 1993-09-08 |
NZ269991A (en) | 1999-07-29 |
AU7370994A (en) | 1995-02-20 |
EP0711160A1 (fr) | 1996-05-15 |
CA2167842A1 (fr) | 1995-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 19960201 |
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RAX | Requested extension states of the european patent have changed |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 19980722 |
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18D | Application deemed to be withdrawn |
Effective date: 19981009 |
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