EP0659192A4 - Novel antibodies for conferring passive immunity against infection by a pathogen in humans. - Google Patents

Novel antibodies for conferring passive immunity against infection by a pathogen in humans.

Info

Publication number
EP0659192A4
EP0659192A4 EP93921412A EP93921412A EP0659192A4 EP 0659192 A4 EP0659192 A4 EP 0659192A4 EP 93921412 A EP93921412 A EP 93921412A EP 93921412 A EP93921412 A EP 93921412A EP 0659192 A4 EP0659192 A4 EP 0659192A4
Authority
EP
European Patent Office
Prior art keywords
pathogen
humans
immunity against
against infection
passive immunity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93921412A
Other languages
German (de)
French (fr)
Other versions
EP0659192A1 (en
Inventor
Mitchell Stuart Gross
Martin Rosenberg
Jerald Charles Sadoff
Stephen Hoffman
Daniel R Sylvester
Yupin Charoenvit
Mark Hurle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
US Department of Army
US Department of Navy
SmithKline Beecham Corp
Original Assignee
US Department of Health and Human Services
US Department of Army
US Department of Navy
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, US Department of Army, US Department of Navy, SmithKline Beecham Corp filed Critical US Department of Health and Human Services
Publication of EP0659192A1 publication Critical patent/EP0659192A1/en
Publication of EP0659192A4 publication Critical patent/EP0659192A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
EP93921412A 1992-09-09 1993-09-08 Novel antibodies for conferring passive immunity against infection by a pathogen in humans. Withdrawn EP0659192A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94165492A 1992-09-09 1992-09-09
US941654 1992-09-09
PCT/US1993/008435 WO1994005690A1 (en) 1992-09-09 1993-09-08 Novel antibodies for conferring passive immunity against infection by a pathogen in humans

Publications (2)

Publication Number Publication Date
EP0659192A1 EP0659192A1 (en) 1995-06-28
EP0659192A4 true EP0659192A4 (en) 1996-09-11

Family

ID=25476840

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93921412A Withdrawn EP0659192A4 (en) 1992-09-09 1993-09-08 Novel antibodies for conferring passive immunity against infection by a pathogen in humans.

Country Status (9)

Country Link
EP (1) EP0659192A4 (en)
JP (1) JPH08500979A (en)
KR (1) KR950703573A (en)
CN (1) CN1087681A (en)
AU (1) AU4851193A (en)
CA (1) CA2143417A1 (en)
NZ (1) NZ256232A (en)
WO (1) WO1994005690A1 (en)
ZA (1) ZA936260B (en)

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EP0782626A1 (en) * 1994-09-19 1997-07-09 Rijkslandbouwuniversiteit Wageningen Gene constructs encoding crop-protecting agents, as well as transformed plants containing and expressing such constructs, and methods of controlling plague organisms and pathogens in crops
SE9500148D0 (en) * 1995-01-18 1995-01-18 Bioinvent Internatioal Ab Antibodies for use in cancer therapy and diagnosis
AUPP221098A0 (en) 1998-03-06 1998-04-02 Diatech Pty Ltd V-like domain binding molecules
US6455677B1 (en) 1998-04-30 2002-09-24 Boehringer Ingelheim International Gmbh FAPα-specific antibody with improved producibility
EP0953639A1 (en) * 1998-04-30 1999-11-03 Boehringer Ingelheim International GmbH FAPalpha-specific antibody with improved producibility
US7829084B2 (en) 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
AU2002241922B2 (en) * 2001-01-17 2007-10-25 Aptevo Research And Development Llc Binding domain-immunoglobulin fusion proteins
AU2008200400B2 (en) * 2001-01-17 2012-06-07 Aptevo Research And Development Llc Binding domain-immunoglobulin fusion proteins
AU2002256985B8 (en) * 2001-01-26 2008-03-20 Inhibitex, Inc Monoclonal antibodies to the ClfA protein and method of use in treating or preventing infections
JP4794301B2 (en) 2003-06-11 2011-10-19 中外製薬株式会社 Antibody production method
US7754209B2 (en) 2003-07-26 2010-07-13 Trubion Pharmaceuticals Binding constructs and methods for use thereof
TW200530269A (en) 2003-12-12 2005-09-16 Chugai Pharmaceutical Co Ltd Anti-Mpl antibodies
US10011858B2 (en) * 2005-03-31 2018-07-03 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
TW200722518A (en) 2005-03-31 2007-06-16 Chugai Pharmaceutical Co Ltd Sc(fv)2 structural isomers
JP5085322B2 (en) 2005-06-10 2012-11-28 中外製薬株式会社 Pharmaceutical composition containing sc (Fv) 2
JP5068167B2 (en) 2005-06-10 2012-11-07 中外製薬株式会社 Stabilizer for protein preparation containing meglumine and use thereof
DK1912675T3 (en) 2005-07-25 2014-03-24 Emergent Product Dev Seattle B-cell reduction using specific and cd37-cd20-specific binding molecules
ES2654040T3 (en) 2006-03-31 2018-02-12 Chugai Seiyaku Kabushiki Kaisha Antibody modification method for the purification of bispecific antibodies
DK3056568T3 (en) 2006-03-31 2021-11-01 Chugai Pharmaceutical Co Ltd PROCEDURES FOR CONTROL OF THE BLOOD PHARMACOKINETICS OF ANTIBODIES
JP2009539413A (en) 2006-06-12 2009-11-19 トゥルビオン・ファーマシューティカルズ・インコーポレーテッド Single-chain multivalent binding protein with effector function
CN106519025B (en) 2007-09-26 2021-04-23 中外制药株式会社 Method for changing isoelectric point of antibody by using amino acid substitution of CDR
CL2008002886A1 (en) 2007-09-26 2009-12-04 Chugai Pharmaceutical Co Ltd Constant region of a human antibody; anti-interleukin-6 (yl-6) receptor antibody and pharmaceutical composition comprising it.
ES2368700T3 (en) 2008-04-11 2011-11-21 Emergent Product Development Seattle, Llc IMMUNOTHERAPEUTIC AGENT FOR CD37 AND COMBINATION WITH A BIFUNCTIONAL CHEMOTHERAPEUTIC AGENT OF THE SAME.
JP5787446B2 (en) 2009-03-19 2015-09-30 中外製薬株式会社 Antibody constant region variants
WO2010107110A1 (en) 2009-03-19 2010-09-23 中外製薬株式会社 Antibody constant region variant
EP2473530B1 (en) * 2009-09-03 2015-04-22 Vancouver Biotech Ltd. Monoclonal antibodies against gonadotropin-releasing hormone receptor
WO2011037158A1 (en) 2009-09-24 2011-03-31 中外製薬株式会社 Modified antibody constant regions
US10435458B2 (en) 2010-03-04 2019-10-08 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variants with reduced Fcgammar binding
TR201802772T4 (en) 2010-11-17 2018-03-21 Chugai Pharmaceutical Co Ltd Multi-specific antigen binding molecule with alternative function for the function of blood coagulation factor VIII.
CN109134658B (en) 2011-10-31 2022-10-14 中外制药株式会社 Antigen binding molecules that control association of heavy and light chains
KR102353885B1 (en) 2013-03-13 2022-01-20 이미지냅 인코포레이티드 Antigen binding constructs to cd8
BR112016006197B1 (en) 2013-09-27 2023-04-11 Chugai Seiyaku Kabushiki Kaisha METHOD FOR PRODUCING A BISPECIFIC POLYPEPTIDE ANTIBODY
FR3025517B1 (en) 2014-09-10 2016-12-23 Repropharm LIGANDS POTENTIATING THE BIOACTIVITY OF GONADOTROPHINS
MA40764A (en) 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd THERAPEUTIC AGENT INDUCING CYTOTOXICITY
EP3279216A4 (en) 2015-04-01 2019-06-19 Chugai Seiyaku Kabushiki Kaisha Method for producing polypeptide hetero-oligomer
NZ739721A (en) 2015-08-07 2019-09-27 Imaginab Inc Antigen binding constructs to target molecules
EP3352760A4 (en) 2015-09-21 2019-03-06 Aptevo Research and Development LLC Cd3 binding polypeptides
WO2017115773A1 (en) 2015-12-28 2017-07-06 中外製薬株式会社 Method for promoting efficiency of purification of fc region-containing polypeptide
TW202342540A (en) 2016-03-14 2023-11-01 日商中外製藥股份有限公司 Cell injury inducing therapeutic drug for use in cancer therapy
WO2018147960A1 (en) 2017-02-08 2018-08-16 Imaginab, Inc. Extension sequences for diabodies

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632909A (en) * 1983-10-31 1986-12-30 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies which block infectivity of malarial parasites to mosquitoes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63267295A (en) * 1986-12-03 1988-11-04 Sumitomo Chem Co Ltd Human antibody, antibody gene and corresponding recombinant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632909A (en) * 1983-10-31 1986-12-30 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies which block infectivity of malarial parasites to mosquitoes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
D. SYLVESTER ET AL.: "Construction and in-vitro characterization of a humanized monoclonal antibody against Plasmodium falciparum sporozoites.", THE AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, vol. 47, no. 4 suppl., October 1992 (1992-10-01), LAWRENCE, USA, pages 233, XP002007068 *
L. RIECHMANN ET AL.: "Reshaping human antibodies for therapy.", NATURE, vol. 332, 24 March 1988 (1988-03-24), LONDON, GB, pages 323 - 327, XP002007067 *
See also references of WO9405690A1 *

Also Published As

Publication number Publication date
JPH08500979A (en) 1996-02-06
KR950703573A (en) 1995-09-20
WO1994005690A1 (en) 1994-03-17
CA2143417A1 (en) 1994-03-17
AU4851193A (en) 1994-03-29
EP0659192A1 (en) 1995-06-28
CN1087681A (en) 1994-06-08
NZ256232A (en) 1997-02-24
ZA936260B (en) 1994-03-18

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