SE9500148D0 - Antibodies for use in cancer therapy and diagnosis - Google Patents

Antibodies for use in cancer therapy and diagnosis

Info

Publication number
SE9500148D0
SE9500148D0 SE9500148A SE9500148A SE9500148D0 SE 9500148 D0 SE9500148 D0 SE 9500148D0 SE 9500148 A SE9500148 A SE 9500148A SE 9500148 A SE9500148 A SE 9500148A SE 9500148 D0 SE9500148 D0 SE 9500148D0
Authority
SE
Sweden
Prior art keywords
diagnosis
cancer
antibody
antibodies
therapy
Prior art date
Application number
SE9500148A
Other languages
Swedish (sv)
Inventor
Roland Carlsson
Bo Jansson
Original Assignee
Bioinvent Internatioal Ab
Pronova As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioinvent Internatioal Ab, Pronova As filed Critical Bioinvent Internatioal Ab
Priority to SE9500148A priority Critical patent/SE9500148D0/en
Publication of SE9500148D0 publication Critical patent/SE9500148D0/en
Priority to PCT/SE1996/000029 priority patent/WO1996022310A1/en
Priority to AU44991/96A priority patent/AU4499196A/en

Links

Abstract

The present invention discloses the PA1-3F10 monoclonal antibody and a hybridoma cell line producing it. The antibody is shown to bind to a variety of carcinomas and malignant cells with haematopoietic origin with a high intensity and degree of selectivity as demonstrated by immunohistochemistry analysis and cell binding assays. The invention also includes antibodies having substantially the same binding specificity as the monoclonal antibody PA1-3F10, and mutants, derivatives, functional equivalents or fragments of the antibody. Applications of the antibodies include the therapy or diagnosis of cancer, e.g. in targetting cytotoxic compounds to cancer cells. In particular, the present invention relates to cancer therapy and diagnosis of colorectal cancer.
SE9500148A 1995-01-18 1995-01-18 Antibodies for use in cancer therapy and diagnosis SE9500148D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9500148A SE9500148D0 (en) 1995-01-18 1995-01-18 Antibodies for use in cancer therapy and diagnosis
PCT/SE1996/000029 WO1996022310A1 (en) 1995-01-18 1996-01-15 Antibodies for use in cancer therapy and diagnosis
AU44991/96A AU4499196A (en) 1995-01-18 1996-01-15 Antibodies for use in cancer therapy and diagnosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500148A SE9500148D0 (en) 1995-01-18 1995-01-18 Antibodies for use in cancer therapy and diagnosis

Publications (1)

Publication Number Publication Date
SE9500148D0 true SE9500148D0 (en) 1995-01-18

Family

ID=20396855

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9500148A SE9500148D0 (en) 1995-01-18 1995-01-18 Antibodies for use in cancer therapy and diagnosis

Country Status (3)

Country Link
AU (1) AU4499196A (en)
SE (1) SE9500148D0 (en)
WO (1) WO1996022310A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10016877A1 (en) 2000-04-05 2001-10-18 Scintec Diagnostics Gmbh Zug (Glyco) proteins with high immunoreactivity and a process for their preparation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172686A (en) * 1985-04-22 1986-10-23 Hybritech Inc ANTIGEN DERIVED FROM HUMAN TISSUE, PROCEDURE FOR USING THE ANTIGEN TO MAKE MONOCLONAL ANTIBODIES FOR DIAGNOSIS AND TREATMENT OF CANCER, PROCEDURE FOR DETECTION OF CANCER, AND OTHER
JPS63157995A (en) * 1986-12-18 1988-06-30 Kyowa Hakko Kogyo Co Ltd Anti-human colon carcinoma monoclonal antibody acc-574
US4892933A (en) * 1988-04-20 1990-01-09 New England Deaconess Hospital Corporation Monoclonal antibody for colorectal carcinoma
CA2065874C (en) * 1989-09-15 2001-12-11 Joseph P. Brown Hybridoma ct43 producing a monoclonal antibody to a mucin epitope of colorectal cancer
EP0519866A1 (en) * 1991-06-18 1992-12-23 Ciba-Geigy Ag Novel anti-HIV antibodies
ZA936260B (en) * 1992-09-09 1994-03-18 Smithkline Beecham Corp Novel antibodies for conferring passive immunity against infection by a pathogen in man
WO1994012214A1 (en) * 1992-12-01 1994-06-09 Protein Design Labs, Inc. Humanized antibodies reactive with cd18

Also Published As

Publication number Publication date
AU4499196A (en) 1996-08-07
WO1996022310A1 (en) 1996-07-25

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