SE9500148D0 - Antibodies for use in cancer therapy and diagnosis - Google Patents
Antibodies for use in cancer therapy and diagnosisInfo
- Publication number
- SE9500148D0 SE9500148D0 SE9500148A SE9500148A SE9500148D0 SE 9500148 D0 SE9500148 D0 SE 9500148D0 SE 9500148 A SE9500148 A SE 9500148A SE 9500148 A SE9500148 A SE 9500148A SE 9500148 D0 SE9500148 D0 SE 9500148D0
- Authority
- SE
- Sweden
- Prior art keywords
- diagnosis
- cancer
- antibody
- antibodies
- therapy
- Prior art date
Links
Abstract
The present invention discloses the PA1-3F10 monoclonal antibody and a hybridoma cell line producing it. The antibody is shown to bind to a variety of carcinomas and malignant cells with haematopoietic origin with a high intensity and degree of selectivity as demonstrated by immunohistochemistry analysis and cell binding assays. The invention also includes antibodies having substantially the same binding specificity as the monoclonal antibody PA1-3F10, and mutants, derivatives, functional equivalents or fragments of the antibody. Applications of the antibodies include the therapy or diagnosis of cancer, e.g. in targetting cytotoxic compounds to cancer cells. In particular, the present invention relates to cancer therapy and diagnosis of colorectal cancer.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9500148A SE9500148D0 (en) | 1995-01-18 | 1995-01-18 | Antibodies for use in cancer therapy and diagnosis |
PCT/SE1996/000029 WO1996022310A1 (en) | 1995-01-18 | 1996-01-15 | Antibodies for use in cancer therapy and diagnosis |
AU44991/96A AU4499196A (en) | 1995-01-18 | 1996-01-15 | Antibodies for use in cancer therapy and diagnosis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9500148A SE9500148D0 (en) | 1995-01-18 | 1995-01-18 | Antibodies for use in cancer therapy and diagnosis |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9500148D0 true SE9500148D0 (en) | 1995-01-18 |
Family
ID=20396855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9500148A SE9500148D0 (en) | 1995-01-18 | 1995-01-18 | Antibodies for use in cancer therapy and diagnosis |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU4499196A (en) |
SE (1) | SE9500148D0 (en) |
WO (1) | WO1996022310A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10016877A1 (en) | 2000-04-05 | 2001-10-18 | Scintec Diagnostics Gmbh Zug | (Glyco) proteins with high immunoreactivity and a process for their preparation |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK172686A (en) * | 1985-04-22 | 1986-10-23 | Hybritech Inc | ANTIGEN DERIVED FROM HUMAN TISSUE, PROCEDURE FOR USING THE ANTIGEN TO MAKE MONOCLONAL ANTIBODIES FOR DIAGNOSIS AND TREATMENT OF CANCER, PROCEDURE FOR DETECTION OF CANCER, AND OTHER |
JPS63157995A (en) * | 1986-12-18 | 1988-06-30 | Kyowa Hakko Kogyo Co Ltd | Anti-human colon carcinoma monoclonal antibody acc-574 |
US4892933A (en) * | 1988-04-20 | 1990-01-09 | New England Deaconess Hospital Corporation | Monoclonal antibody for colorectal carcinoma |
CA2065874C (en) * | 1989-09-15 | 2001-12-11 | Joseph P. Brown | Hybridoma ct43 producing a monoclonal antibody to a mucin epitope of colorectal cancer |
EP0519866A1 (en) * | 1991-06-18 | 1992-12-23 | Ciba-Geigy Ag | Novel anti-HIV antibodies |
ZA936260B (en) * | 1992-09-09 | 1994-03-18 | Smithkline Beecham Corp | Novel antibodies for conferring passive immunity against infection by a pathogen in man |
WO1994012214A1 (en) * | 1992-12-01 | 1994-06-09 | Protein Design Labs, Inc. | Humanized antibodies reactive with cd18 |
-
1995
- 1995-01-18 SE SE9500148A patent/SE9500148D0/en unknown
-
1996
- 1996-01-15 AU AU44991/96A patent/AU4499196A/en not_active Abandoned
- 1996-01-15 WO PCT/SE1996/000029 patent/WO1996022310A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
AU4499196A (en) | 1996-08-07 |
WO1996022310A1 (en) | 1996-07-25 |
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