EP0642829A1 - Pipette en matière plastique - Google Patents

Pipette en matière plastique Download PDF

Info

Publication number
EP0642829A1
EP0642829A1 EP94113354A EP94113354A EP0642829A1 EP 0642829 A1 EP0642829 A1 EP 0642829A1 EP 94113354 A EP94113354 A EP 94113354A EP 94113354 A EP94113354 A EP 94113354A EP 0642829 A1 EP0642829 A1 EP 0642829A1
Authority
EP
European Patent Office
Prior art keywords
pipette
piston
sliding layer
pipette according
electrically conductive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94113354A
Other languages
German (de)
English (en)
Inventor
Holger Pufahl
Martin Schleicher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of EP0642829A1 publication Critical patent/EP0642829A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips

Definitions

  • the present invention relates to a pipette with a pipette body and a pipette piston, this pipette being usable as a liquid detector, with either the pipette body or the pipette piston being electrically conductive.
  • Such a pipette is e.g. B. described in EP-A-0 226 867.
  • the execution of such a plastic syringe usually consists of two different materials such. B. polypropylene (PP) and polyethylene (PE).
  • the body is preferably made from the mechanically more stable material (PP). Since the conductivity z. B. is achieved by embedding graphite in the plastic, it is obvious to make the pipette piston from the conductive material, so that the possibility of optical control of the liquid sucked into the pipette is not affected by the coloring of the pipette body.
  • such pipettes have at least one sealing lip that comes into contact with the media to be pipetted.
  • detergents for use in such solutions and the detergent concentrations used are known to the person skilled in the art.
  • the object underlying the present invention was therefore to find a pipette which does not have the above disadvantages.
  • the pipette according to the invention thus preferably has an electrically conductive pipette plunger, which is essentially made of plastic, and an essentially transparent pipette body, the pipette plunger and pipette body being separated, at least in the areas in which they are in contact, by a layer of a sufficiently lubricious material are.
  • the pipette is a so-called "positive displacement pipette" (dead volume-free pipette), the separation between the pipette body and pipette piston preferably being coated by coating the pipette body and / or the pipette piston with silicone oil at temperatures above 50, very preferably at temperatures of about 70 ° C.
  • Suitable silicone oils are known per se to the person skilled in the art, e.g. B. Baysilone® oil MPH 1000 or paste (Bayer, Leverkusen, Germany) and oil AK 12500 (WACKER).
  • this sliding layer is coated with materials known to the person skilled in the art, such as, for. B. a liquid PTFE product, e.g. B. VYDAX®500 or OSIXO TS (Costenoble) or a chemically related product.
  • a liquid PTFE product e.g. B. VYDAX®500 or OSIXO TS (Costenoble) or a chemically related product.
  • this sliding layer is generated in that a seal between the piston and body z.
  • an O-ring is inserted so that the piston and body no longer touch directly. Suitable materials are known per se to the person skilled in the art.
  • the ring is preferably made of silicone rubber, rubber or another plastic which has low friction.
  • a, preferably mechanically self-supporting insert made of a particularly slidable plastic, e.g. B. PTFE inserted.
  • the pipette according to FIG. 1 consists of a pipette body (3) with the inside (4) and a pipette piston (2), the pipette piston (2) consisting of plastic made electrically conductive and the piston (2) provided with a sealing lip (7) is.
  • the pipette piston (2) has an end section (1) consisting essentially of two disks, on which the pipette piston (2) can be manipulated in an automatic analyzer with the aid of a receiving device.
  • the pipette body (3) has a predominantly disc-shaped end section (8) which is used for manipulation in the automatic analyzer.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP94113354A 1993-09-09 1994-08-26 Pipette en matière plastique Withdrawn EP0642829A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19934330562 DE4330562A1 (de) 1993-09-09 1993-09-09 Kunststoffpipette
DE4330562 1993-09-09

Publications (1)

Publication Number Publication Date
EP0642829A1 true EP0642829A1 (fr) 1995-03-15

Family

ID=6497272

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94113354A Withdrawn EP0642829A1 (fr) 1993-09-09 1994-08-26 Pipette en matière plastique

Country Status (5)

Country Link
EP (1) EP0642829A1 (fr)
JP (1) JPH07171423A (fr)
AU (1) AU7169894A (fr)
CA (1) CA2131653A1 (fr)
DE (1) DE4330562A1 (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115026A1 (fr) * 2009-04-02 2010-10-07 Abbott Point Of Care, Inc. Procédé et dispositif permettant de transférer des échantillons de fluides biologiques
US7903241B2 (en) 2008-03-21 2011-03-08 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US7929121B2 (en) 2008-03-21 2011-04-19 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
US7951599B2 (en) 2008-03-21 2011-05-31 Abbott Point Of Care, Inc. Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US7995194B2 (en) 2008-04-02 2011-08-09 Abbott Point Of Care, Inc. Virtual separation of bound and free label in a ligand assay for performing immunoassays of biological fluids, including whole blood
US8045165B2 (en) 2008-03-21 2011-10-25 Abbott Point Of Care, Inc. Method and apparatus for determining a focal position of an imaging device adapted to image a biologic sample
US8081303B2 (en) 2008-03-21 2011-12-20 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
WO2012085006A1 (fr) * 2010-12-21 2012-06-28 Ge Healthcare Uk Limited Dispositif et procédé de filtration
US8326008B2 (en) 2008-04-09 2012-12-04 Abbott Point Of Care, Inc. Method for measuring the area of a sample disposed within an analysis chamber
US8472693B2 (en) 2010-03-18 2013-06-25 Abbott Point Of Care, Inc. Method for determining at least one hemoglobin related parameter of a whole blood sample
US8837803B2 (en) 2009-12-31 2014-09-16 Abbott Point Of Care, Inc. Method and apparatus for determining mean cell volume of red blood cells

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3473409B2 (ja) * 1998-06-11 2003-12-02 松下電器産業株式会社 分注装置
DE102006031460B4 (de) * 2006-07-07 2008-10-30 Eppendorf Ag Pipettiervorrichtung
JP2011149767A (ja) * 2010-01-20 2011-08-04 Fukae Kasei Kk ピペット装置
CN103080724B (zh) 2010-04-26 2016-04-13 电流感应器公司 便携式粘度计

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1048267A (fr) * 1951-03-29 1953-12-21 Perfectionnements apportés aux seringues à injection et en particulier à celles fabriquées en matière moulée
US2895773A (en) * 1956-10-22 1959-07-21 Robert K Mcconnaughey Variable diameter tensed ring piston
CH580427A5 (fr) * 1975-07-28 1976-10-15 Contraves Ag
EP0226867A2 (fr) * 1985-12-17 1987-07-01 Hamilton Bonaduz AG Pipette et dispositif de pipettage
US4822632A (en) * 1985-05-16 1989-04-18 Becton, Dickinson And Company Ionizing plasma lubricant method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1048267A (fr) * 1951-03-29 1953-12-21 Perfectionnements apportés aux seringues à injection et en particulier à celles fabriquées en matière moulée
US2895773A (en) * 1956-10-22 1959-07-21 Robert K Mcconnaughey Variable diameter tensed ring piston
CH580427A5 (fr) * 1975-07-28 1976-10-15 Contraves Ag
US4822632A (en) * 1985-05-16 1989-04-18 Becton, Dickinson And Company Ionizing plasma lubricant method
EP0226867A2 (fr) * 1985-12-17 1987-07-01 Hamilton Bonaduz AG Pipette et dispositif de pipettage

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8310659B2 (en) 2008-03-21 2012-11-13 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
US7951599B2 (en) 2008-03-21 2011-05-31 Abbott Point Of Care, Inc. Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US9733233B2 (en) 2008-03-21 2017-08-15 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
US7929122B2 (en) 2008-03-21 2011-04-19 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US8310658B2 (en) 2008-03-21 2012-11-13 Abbott Point Of Care, Inc. Method and apparatus for identifying reticulocytes within a blood sample
US8778687B2 (en) 2008-03-21 2014-07-15 Abbott Point Of Care, Inc. Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US8045165B2 (en) 2008-03-21 2011-10-25 Abbott Point Of Care, Inc. Method and apparatus for determining a focal position of an imaging device adapted to image a biologic sample
US8077296B2 (en) 2008-03-21 2011-12-13 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
US8081303B2 (en) 2008-03-21 2011-12-20 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
US8133738B2 (en) 2008-03-21 2012-03-13 Abbott Point Of Care, Inc. Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US8502963B2 (en) 2008-03-21 2013-08-06 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
US8467063B2 (en) 2008-03-21 2013-06-18 Abbott Point Of Care, Inc. Method and apparatus for determining a focal position of an imaging device adapted to image a biologic sample
US8269954B2 (en) 2008-03-21 2012-09-18 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
US8284384B2 (en) 2008-03-21 2012-10-09 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
US7929121B2 (en) 2008-03-21 2011-04-19 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
US7903241B2 (en) 2008-03-21 2011-03-08 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US8361799B2 (en) 2008-03-21 2013-01-29 Abbott Point Of Care, Inc. Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US8221985B2 (en) 2008-04-02 2012-07-17 Abbott Point Of Care, Inc. Self-calibrating gradient dilution in a constituent assay and gradient dilution apparatus performed in a thin film sample
US8319954B2 (en) 2008-04-02 2012-11-27 Abbott Point Of Care, Inc. Virtual separation of bound and free label in a ligand assay for performing immunoassays of biological fluids, including whole blood
US8569076B2 (en) 2008-04-02 2013-10-29 Abbott Point Of Care, Inc. Method for serologic agglutination and other immunoassays performed in a thin film fluid sample
US7995194B2 (en) 2008-04-02 2011-08-09 Abbott Point Of Care, Inc. Virtual separation of bound and free label in a ligand assay for performing immunoassays of biological fluids, including whole blood
US8842264B2 (en) 2008-04-02 2014-09-23 Abbott Point Of Care, Inc. Virtual separation of bound and free label in a ligand assay for performing immunoassays of biological fluids, including whole blood
US9274094B2 (en) 2008-04-02 2016-03-01 Abbott Point Of Care, Inc. Self-calibrating gradient dilution in a constitutent assay and gradient dilution apparatus performed in a thin film sample
US8326008B2 (en) 2008-04-09 2012-12-04 Abbott Point Of Care, Inc. Method for measuring the area of a sample disposed within an analysis chamber
WO2010115026A1 (fr) * 2009-04-02 2010-10-07 Abbott Point Of Care, Inc. Procédé et dispositif permettant de transférer des échantillons de fluides biologiques
US8837803B2 (en) 2009-12-31 2014-09-16 Abbott Point Of Care, Inc. Method and apparatus for determining mean cell volume of red blood cells
US8472693B2 (en) 2010-03-18 2013-06-25 Abbott Point Of Care, Inc. Method for determining at least one hemoglobin related parameter of a whole blood sample
WO2012085006A1 (fr) * 2010-12-21 2012-06-28 Ge Healthcare Uk Limited Dispositif et procédé de filtration
US9919248B2 (en) 2010-12-21 2018-03-20 Ge Healthcare Uk Limited Filtration device and method

Also Published As

Publication number Publication date
JPH07171423A (ja) 1995-07-11
CA2131653A1 (fr) 1995-03-10
AU7169894A (en) 1995-03-23
DE4330562A1 (de) 1995-03-16

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