EP0629407A3 - Utilisation de protéine C humaine dans l'empêchement et le traitement des dépÔts de trombocytes. - Google Patents

Utilisation de protéine C humaine dans l'empêchement et le traitement des dépÔts de trombocytes. Download PDF

Info

Publication number
EP0629407A3
EP0629407A3 EP94109293A EP94109293A EP0629407A3 EP 0629407 A3 EP0629407 A3 EP 0629407A3 EP 94109293 A EP94109293 A EP 94109293A EP 94109293 A EP94109293 A EP 94109293A EP 0629407 A3 EP0629407 A3 EP 0629407A3
Authority
EP
European Patent Office
Prior art keywords
thrombocytes
treatment
prevention
human protein
depositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP94109293A
Other languages
German (de)
English (en)
Other versions
EP0629407B1 (fr
EP0629407A2 (fr
Inventor
Johann Dr Eibl
Hans-Peter Schwarz
Miquel Lozano-Molero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter AG
Original Assignee
Immuno AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno AG filed Critical Immuno AG
Publication of EP0629407A2 publication Critical patent/EP0629407A2/fr
Publication of EP0629407A3 publication Critical patent/EP0629407A3/fr
Application granted granted Critical
Publication of EP0629407B1 publication Critical patent/EP0629407B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP94109293A 1993-06-18 1994-06-16 Utilisation de protéine C humaine dans l'empêchement et le traitement des dépôts de thrombocytes Expired - Lifetime EP0629407B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4320294A DE4320294A1 (de) 1993-06-18 1993-06-18 Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
DE4320294 1993-06-18

Publications (3)

Publication Number Publication Date
EP0629407A2 EP0629407A2 (fr) 1994-12-21
EP0629407A3 true EP0629407A3 (fr) 1995-05-24
EP0629407B1 EP0629407B1 (fr) 2001-09-12

Family

ID=6490672

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94109293A Expired - Lifetime EP0629407B1 (fr) 1993-06-18 1994-06-16 Utilisation de protéine C humaine dans l'empêchement et le traitement des dépôts de thrombocytes

Country Status (14)

Country Link
US (1) US5614493A (fr)
EP (1) EP0629407B1 (fr)
JP (1) JP3106059B2 (fr)
AT (2) AT407704B (fr)
AU (1) AU680894B2 (fr)
CA (1) CA2126135C (fr)
CZ (1) CZ148294A3 (fr)
DE (2) DE4320294A1 (fr)
DK (1) DK0629407T3 (fr)
ES (1) ES2162829T3 (fr)
FI (1) FI942941A (fr)
HU (1) HU217609B (fr)
NO (1) NO942298L (fr)
SK (1) SK282358B6 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9806966D0 (en) * 1998-03-31 1998-06-03 Ppl Therapeutics Scotland Ltd Bioloically modified device
JP2004535461A (ja) * 2001-07-19 2004-11-25 ディーエムアイ バイオサイエンシズ インコーポレイテッド プロテインｃの不活性化を抑制するための銅キレート剤の使用
EP2539448B1 (fr) * 2010-02-26 2016-12-14 The Children's Hospital of Philadelphia Zymogène de la protéine c et ses procédés d'utilisation pour prévenir les métastases cancéreuses

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191606A2 (fr) * 1985-02-08 1986-08-20 Eli Lilly And Company Vecteurs et méthodes d'expression d'activité de protéine C humaine
EP0443875A2 (fr) * 1990-02-23 1991-08-28 Eli Lilly And Company Vecteurs et composés pour l'expression de formes zymogènes de la protéine C humaine
EP0575054A2 (fr) * 1992-05-21 1993-12-22 Eli Lilly And Company Dérivés de la protéine C

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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191606A2 (fr) * 1985-02-08 1986-08-20 Eli Lilly And Company Vecteurs et méthodes d'expression d'activité de protéine C humaine
EP0443875A2 (fr) * 1990-02-23 1991-08-28 Eli Lilly And Company Vecteurs et composés pour l'expression de formes zymogènes de la protéine C humaine
EP0575054A2 (fr) * 1992-05-21 1993-12-22 Eli Lilly And Company Dérivés de la protéine C

Also Published As

Publication number Publication date
FI942941A0 (fi) 1994-06-17
DK0629407T3 (da) 2001-11-12
DE69428231D1 (de) 2001-10-18
FI942941A (fi) 1994-12-19
NO942298D0 (no) 1994-06-17
AU680894B2 (en) 1997-08-14
HU217609B (hu) 2000-03-28
NO942298L (no) 1994-12-19
ATA119394A (de) 2000-10-15
US5614493A (en) 1997-03-25
ES2162829T3 (es) 2002-01-16
DE69428231T2 (de) 2002-06-13
CA2126135C (fr) 2002-02-19
CA2126135A1 (fr) 1994-12-19
JPH0748275A (ja) 1995-02-21
EP0629407B1 (fr) 2001-09-12
AT407704B (de) 2001-05-25
ATE205396T1 (de) 2001-09-15
DE4320294A1 (de) 1994-12-22
JP3106059B2 (ja) 2000-11-06
SK282358B6 (sk) 2002-01-07
AU6471994A (en) 1994-12-22
SK74894A3 (en) 1995-05-10
HUT67074A (en) 1995-01-30
EP0629407A2 (fr) 1994-12-21
HU9401817D0 (en) 1994-09-28
CZ148294A3 (en) 1995-01-18

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