EP0620860A1 - Herstellung rekombinanter borrelia-proteine - Google Patents
Herstellung rekombinanter borrelia-proteineInfo
- Publication number
- EP0620860A1 EP0620860A1 EP92922390A EP92922390A EP0620860A1 EP 0620860 A1 EP0620860 A1 EP 0620860A1 EP 92922390 A EP92922390 A EP 92922390A EP 92922390 A EP92922390 A EP 92922390A EP 0620860 A1 EP0620860 A1 EP 0620860A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- protein
- plasmid
- ospa
- gene
- lipoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77904891A | 1991-10-18 | 1991-10-18 | |
| US779048 | 1991-10-18 | ||
| US88876592A | 1992-05-27 | 1992-05-27 | |
| US888765 | 1992-05-27 | ||
| PCT/US1992/008697 WO1993008299A1 (en) | 1991-10-18 | 1992-10-16 | Preparation of recombinant borrelia proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0620860A1 true EP0620860A1 (de) | 1994-10-26 |
| EP0620860A4 EP0620860A4 (en) | 1997-05-02 |
Family
ID=27119531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP92922390A Withdrawn EP0620860A4 (en) | 1991-10-18 | 1992-10-16 | Preparation of recombinant borrelia proteins. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0620860A4 (de) |
| JP (1) | JPH06511154A (de) |
| AU (1) | AU676140B2 (de) |
| CA (1) | CA2121121C (de) |
| FI (1) | FI941749A (de) |
| IL (1) | IL103462A0 (de) |
| NO (1) | NO310417B1 (de) |
| PT (1) | PT100980B (de) |
| WO (1) | WO1993008299A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4015911A1 (de) | 1989-09-19 | 1991-03-28 | Max Planck Gesellschaft | Impfstoff gegen die lyme-krankheit |
| US6676942B1 (en) | 1991-08-15 | 2004-01-13 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| JPH07501687A (ja) * | 1991-08-15 | 1995-02-23 | スミスクライン・ビーチャム・バイオロジカルス（ソシエテ・アノニム） | ボレリア・ブルグドルフェリのサブグループのｏｓｐ ａ 蛋白、それをコードしている遺伝子およびワクチン |
| CA2105629A1 (en) * | 1992-09-14 | 1994-03-15 | Robert S. Becker | Potentiation of immunogenic response |
| US6248562B1 (en) | 1993-11-01 | 2001-06-19 | Research Foundation State University Of New York | Chimeric proteins comprising borrelia polypeptides and uses therefor |
| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| US6610838B1 (en) | 1997-09-10 | 2003-08-26 | Symbicom Aktiebolag | P13 antigens from Borrelia |
| US6224882B1 (en) | 1997-11-07 | 2001-05-01 | Protein Science Corp. | Insect cells or fractions as adjuvant for antigens |
| GB9811219D0 (en) * | 1998-05-26 | 1998-07-22 | Smithkline Beecham Biolog | Novel process |
| EP1173577A2 (de) * | 1999-04-21 | 2002-01-23 | Boston Medical Center Corporation | Vorbeugung, diagnose und behandlung von lyme-krankheit |
| DK1311540T3 (da) | 2000-08-18 | 2008-04-28 | Brookhaven Sciences Ass Llc | Ændret OspA af Borrelia Burgdorferi |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0418827A1 (de) * | 1989-09-19 | 1991-03-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Impfstoff gegen die Lyme-Krankheit |
| WO1991009870A1 (de) * | 1989-12-22 | 1991-07-11 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff |
| WO1993004175A1 (en) * | 1991-08-15 | 1993-03-04 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of borrelia burgdorferi subgroups, encoding genes and vaccines |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK590288D0 (da) * | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| CA2057536C (en) * | 1990-12-21 | 1999-10-26 | John J. Dunn | Cloning and expression of borrelia lipoproteins |
-
1992
- 1992-10-16 PT PT100980A patent/PT100980B/pt not_active IP Right Cessation
- 1992-10-16 EP EP92922390A patent/EP0620860A4/en not_active Withdrawn
- 1992-10-16 AU AU28011/92A patent/AU676140B2/en not_active Ceased
- 1992-10-16 WO PCT/US1992/008697 patent/WO1993008299A1/en not_active Application Discontinuation
- 1992-10-16 JP JP5507751A patent/JPH06511154A/ja active Pending
- 1992-10-16 CA CA002121121A patent/CA2121121C/en not_active Expired - Fee Related
- 1992-10-18 IL IL103462A patent/IL103462A0/xx unknown
-
1994
- 1994-04-15 NO NO19941376A patent/NO310417B1/no not_active IP Right Cessation
- 1994-04-15 FI FI941749A patent/FI941749A/fi unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0418827A1 (de) * | 1989-09-19 | 1991-03-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Impfstoff gegen die Lyme-Krankheit |
| WO1991009870A1 (de) * | 1989-12-22 | 1991-07-11 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff |
| WO1993004175A1 (en) * | 1991-08-15 | 1993-03-04 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of borrelia burgdorferi subgroups, encoding genes and vaccines |
Non-Patent Citations (2)
| Title |
|---|
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 87, May 1990, WASHINGTON US, pages 3768-3772, XP002025454 SCHAIBLE UE ET AL.: "Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice" * |
| See also references of WO9308299A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| PT100980B (pt) | 1999-07-30 |
| FI941749A0 (fi) | 1994-04-15 |
| JPH06511154A (ja) | 1994-12-15 |
| AU2801192A (en) | 1993-05-21 |
| IL103462A0 (en) | 1993-03-15 |
| PT100980A (pt) | 1994-01-31 |
| NO310417B1 (no) | 2001-07-02 |
| EP0620860A4 (en) | 1997-05-02 |
| NO941376D0 (no) | 1994-04-15 |
| WO1993008299A1 (en) | 1993-04-29 |
| FI941749A (fi) | 1994-05-25 |
| NO941376L (no) | 1994-06-17 |
| AU676140B2 (en) | 1997-03-06 |
| CA2121121A1 (en) | 1993-04-29 |
| CA2121121C (en) | 2003-06-10 |
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