EP0620860A4 - Preparation of recombinant borrelia proteins. - Google Patents

Preparation of recombinant borrelia proteins.

Info

Publication number
EP0620860A4
EP0620860A4 EP92922390A EP92922390A EP0620860A4 EP 0620860 A4 EP0620860 A4 EP 0620860A4 EP 92922390 A EP92922390 A EP 92922390A EP 92922390 A EP92922390 A EP 92922390A EP 0620860 A4 EP0620860 A4 EP 0620860A4
Authority
EP
European Patent Office
Prior art keywords
preparation
borrelia proteins
recombinant borrelia
recombinant
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92922390A
Other languages
English (en)
Other versions
EP0620860A1 (de
Inventor
Lorne Franklin Erdile
Mary-Ann Brandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Sanofi Pasteur Inc
Original Assignee
Connaught Laboratories Ltd
Connaught Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Laboratories Ltd, Connaught Laboratories Inc filed Critical Connaught Laboratories Ltd
Publication of EP0620860A1 publication Critical patent/EP0620860A1/de
Publication of EP0620860A4 publication Critical patent/EP0620860A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP92922390A 1991-10-18 1992-10-16 Preparation of recombinant borrelia proteins. Withdrawn EP0620860A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77904891A 1991-10-18 1991-10-18
US779048 1991-10-18
US88876592A 1992-05-27 1992-05-27
US888765 1992-05-27
PCT/US1992/008697 WO1993008299A1 (en) 1991-10-18 1992-10-16 Preparation of recombinant borrelia proteins

Publications (2)

Publication Number Publication Date
EP0620860A1 EP0620860A1 (de) 1994-10-26
EP0620860A4 true EP0620860A4 (en) 1997-05-02

Family

ID=27119531

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92922390A Withdrawn EP0620860A4 (en) 1991-10-18 1992-10-16 Preparation of recombinant borrelia proteins.

Country Status (9)

Country Link
EP (1) EP0620860A4 (de)
JP (1) JPH06511154A (de)
AU (1) AU676140B2 (de)
CA (1) CA2121121C (de)
FI (1) FI941749A (de)
IL (1) IL103462A0 (de)
NO (1) NO310417B1 (de)
PT (1) PT100980B (de)
WO (1) WO1993008299A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4015911A1 (de) 1989-09-19 1991-03-28 Max Planck Gesellschaft Impfstoff gegen die lyme-krankheit
EP0878545A3 (de) * 1991-08-15 1998-12-16 SMITHKLINE BEECHAM BIOLOGICALS s.a. OspA Proteine von Borrelia Burgdorferi Untergruppen , dafür kodierende Gene sowie Impfstoffe
US6676942B1 (en) 1991-08-15 2004-01-13 Smithkline Beecham Biologicals (S.A.) Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
CA2105629A1 (en) * 1992-09-14 1994-03-15 Robert S. Becker Potentiation of immunogenic response
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
US6248562B1 (en) 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
US6610838B1 (en) 1997-09-10 2003-08-26 Symbicom Aktiebolag P13 antigens from Borrelia
US6224882B1 (en) 1997-11-07 2001-05-01 Protein Science Corp. Insect cells or fractions as adjuvant for antigens
GB9811219D0 (en) * 1998-05-26 1998-07-22 Smithkline Beecham Biolog Novel process
US6667038B1 (en) * 1999-04-21 2003-12-23 Boston Medical Center Corp. Prevention, diagnosis and treatment of lyme disease
WO2002016421A2 (en) 2000-08-18 2002-02-28 Research Foundation Of The State University Of New York Altered ospa of borrelia burgdorferi

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418827A1 (de) * 1989-09-19 1991-03-27 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Impfstoff gegen die Lyme-Krankheit
WO1991009870A1 (de) * 1989-12-22 1991-07-11 Mikrogen Molekularbiologische Entwicklungs-Gmbh Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff
WO1993004175A1 (en) * 1991-08-15 1993-03-04 Smithkline Beecham Biologicals (S.A.) Osp a proteins of borrelia burgdorferi subgroups, encoding genes and vaccines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) * 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
CA2057536C (en) * 1990-12-21 1999-10-26 John J. Dunn Cloning and expression of borrelia lipoproteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418827A1 (de) * 1989-09-19 1991-03-27 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Impfstoff gegen die Lyme-Krankheit
WO1991009870A1 (de) * 1989-12-22 1991-07-11 Mikrogen Molekularbiologische Entwicklungs-Gmbh Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff
WO1993004175A1 (en) * 1991-08-15 1993-03-04 Smithkline Beecham Biologicals (S.A.) Osp a proteins of borrelia burgdorferi subgroups, encoding genes and vaccines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SCHAIBLE UE ET AL.: "Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 87, May 1990 (1990-05-01), WASHINGTON US, pages 3768 - 3772, XP002025454 *
See also references of WO9308299A1 *

Also Published As

Publication number Publication date
NO941376D0 (no) 1994-04-15
AU2801192A (en) 1993-05-21
AU676140B2 (en) 1997-03-06
IL103462A0 (en) 1993-03-15
PT100980B (pt) 1999-07-30
FI941749A (fi) 1994-05-25
NO310417B1 (no) 2001-07-02
FI941749A0 (fi) 1994-04-15
PT100980A (pt) 1994-01-31
WO1993008299A1 (en) 1993-04-29
CA2121121C (en) 2003-06-10
NO941376L (no) 1994-06-17
JPH06511154A (ja) 1994-12-15
CA2121121A1 (en) 1993-04-29
EP0620860A1 (de) 1994-10-26

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20020416