EP0571838A2 - Füllkappe zum Einfüllen von Blut in ein Messröhrchen - Google Patents

Füllkappe zum Einfüllen von Blut in ein Messröhrchen Download PDF

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Publication number
EP0571838A2
EP0571838A2 EP93107871A EP93107871A EP0571838A2 EP 0571838 A2 EP0571838 A2 EP 0571838A2 EP 93107871 A EP93107871 A EP 93107871A EP 93107871 A EP93107871 A EP 93107871A EP 0571838 A2 EP0571838 A2 EP 0571838A2
Authority
EP
European Patent Office
Prior art keywords
measuring tube
filling cap
cap according
closed
section
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93107871A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0571838A3 (enrdf_load_stackoverflow
Inventor
Amerigo Montefiori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUEST MEDICAL AG
Original Assignee
GUEST MEDICAL AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GUEST MEDICAL AG filed Critical GUEST MEDICAL AG
Publication of EP0571838A2 publication Critical patent/EP0571838A2/de
Publication of EP0571838A3 publication Critical patent/EP0571838A3/xx
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs

Definitions

  • the present invention relates to a filler cap according to the preamble of claim 1.
  • Such a filler cap is known, for example, from US Pat. No. 4,622,847. Its stopper is constructed in two parts and forms an overflow chamber for the blood displaced into the measuring tube between the fixed wall and a removable cover.
  • the blood to be examined is first filled into the displacement chamber. Thinner and an anticoagulant are then added to the blood sample and the stopper is placed on the mixing chamber. If the stopper sits tightly on the mixing chamber, the filling cap is shaken and the sample is mixed. Then the plug is removed, placed on the upper end of the measuring tube and the measuring tube is pushed into the displacement chamber with the foot end.
  • This filler cap has the disadvantage that it is comparatively expensive because of its three-part production and, due to the above-mentioned channel in the wall and the ventilation opening in the lid, it does not seal sufficiently when the blood sample is mixed forms, whereby the laboratory person can become infected with the blood sample during sample preparation.
  • a further risk of infection is that after the sample has been mixed, the stopper has to be pulled out of the mixing chamber and put on the measuring tube, as a result of which the lower, infected edge can be touched by the laboratory person.
  • the present invention has for its object to provide a filler cap of the type mentioned, which is much easier to manufacture and handle much safer.
  • the plastic filler cap 1 shown in the drawing has a cylindrical section 3 delimiting a displacement chamber 2, which is closed at the bottom and which adjoins a cylindrical section 5 of larger diameter at the top via a conical section 4.
  • the latter forms a mixing chamber 6.
  • This is closed by a stopper 7 with a cylindrical cross section, the clear cross section of which is closed at the top by a tearable membrane 8.
  • the seal between the section 5 and the plug 7 is ensured by an annular rib 9.
  • the stopper 7 is pulled out of the section 5 and the displacement chamber 2 is partially filled with the blood to be examined.
  • a thinner and an anticoagulant are then added to the blood, unless this was already contained in the filler cap before the blood was added.
  • the plug 7 is reinserted into the section 5. If the stopper 7 sits tightly in section 5, the filler cap 1 is turned upside down (stopper 7 downwards) and shaken until the required homogeneity of the sample is achieved. The filling cap with the stopper 7 is then turned up again, the blood is shaken down into the displacement chamber 2 and a measuring tube 11 is pushed through the membrane 8 from above, bulging against the mixing chamber 6 and then tearing along the predetermined tear point 10. A conical centering zone at the upper end of the plug 7 facilitates the insertion of the measuring tube 11.
  • the measuring tube 11 When the measuring tube 11 is pushed in further, it penetrates an inner ring rib 12 which is arranged at the upper end of the section and lies liquid and gas-tight against the outer wall of the measuring tube 11. The now displaced blood rises in the measuring tube 11 up to the desired zero mark.
  • the distance of the inner ring rib 12 from the bottom of the displacement chamber 2 is selected such that an equal, sufficient amount of blood is always displaced into the measuring tube 11 when it is pushed into the filler cap 1 as far as the bottom.
  • the air displaced in the mixing chamber 6 escapes through the slots 13 which form laterally from the measuring tube and which are created by the gaping apart of the groove 10.
  • the measuring tube is closed at the upper end in a known manner by an (air-permeable) cotton ball or an air-permeable plastic plug, the risk is eliminated. that the blood escapes from the tube at the top and can contaminate the environment.
  • a radial or an annular groove could also be arranged in the membrane 8. It is also possible to choose a membrane with a conical shape instead of a membrane with a flat extension, whereby the cone apex can be directed both outwards and inwards.
  • the thickness of the membrane 8 is preferably 0.3 to 0.6 millimeters. At the bottom of the groove, it is preferably only 0.05 to 0.12 millimeters.
  • FIGS. 4 and 5 A particularly advantageous embodiment of the filler cap 1 is shown in FIGS. 4 and 5.
  • the measuring tube 10 has a cross-sectional taper in the region of its lower end, which consists of four flat, radially symmetrically arranged wall sections 15. These each pass over an inclined surface 16 upwards into the cylindrical inner tube wall. If the measuring tube 10 is inserted into the filler cap 1, it is braked as soon as it hits the inclined surfaces 16.
  • a gradually increasing force is now required to push the tube all the way down onto the filler cap base and thereby radially stretch the filler cap. This greater expenditure of force signals to the operator that the filling process is nearing the end and greater caution, that is to say a slower insertion of the tube, is required if blood leakage is to be avoided.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP93107871A 1992-05-27 1993-05-14 Füllkappe zum Einfüllen von Blut in ein Messröhrchen Withdrawn EP0571838A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH174092A CH685360A5 (de) 1992-05-27 1992-05-27 Füllkappe zum Einfüllen von Blut in ein Messröhrchen.
CH1740/92 1992-05-27

Publications (2)

Publication Number Publication Date
EP0571838A2 true EP0571838A2 (de) 1993-12-01
EP0571838A3 EP0571838A3 (enrdf_load_stackoverflow) 1994-04-20

Family

ID=4217476

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93107871A Withdrawn EP0571838A2 (de) 1992-05-27 1993-05-14 Füllkappe zum Einfüllen von Blut in ein Messröhrchen

Country Status (2)

Country Link
EP (1) EP0571838A2 (enrdf_load_stackoverflow)
CH (1) CH685360A5 (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103063552A (zh) * 2012-08-29 2013-04-24 浙江硕华医用塑料有限公司 一种血沉管组件
US20220401946A1 (en) * 2017-07-27 2022-12-22 Biomerieux, Inc. Isolation tube

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB191221525A (en) * 1912-09-21 1913-09-18 Louis Naglee Bruner Improvements in or relating to the Stoppering of Glass Bottles and the like.
GB2048836B (en) * 1979-04-20 1983-09-28 Guest Ltd Blood testing apparatus
DE2935371C2 (de) * 1979-09-01 1983-07-07 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht Blutsenkunsvorrichtung.
IT1153640B (it) * 1982-11-05 1987-01-14 Italiana L P Spa Apparecchio per la misura della verlocita' di eritrosedimentazione del sangue
DE3421955C2 (de) * 1984-06-13 1986-10-09 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht Blutsenkungsvorrichtung
US4545497A (en) * 1984-11-16 1985-10-08 Millipore Corporation Container cap with frangible septum

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103063552A (zh) * 2012-08-29 2013-04-24 浙江硕华医用塑料有限公司 一种血沉管组件
US20220401946A1 (en) * 2017-07-27 2022-12-22 Biomerieux, Inc. Isolation tube
US12070745B2 (en) * 2017-07-27 2024-08-27 Biomerieux, Inc. Isolation tube woth and endcap

Also Published As

Publication number Publication date
EP0571838A3 (enrdf_load_stackoverflow) 1994-04-20
CH685360A5 (de) 1995-06-15

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