EP0539141A1 - Container for a liquid specimen - Google Patents

Container for a liquid specimen Download PDF

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Publication number
EP0539141A1
EP0539141A1 EP92309546A EP92309546A EP0539141A1 EP 0539141 A1 EP0539141 A1 EP 0539141A1 EP 92309546 A EP92309546 A EP 92309546A EP 92309546 A EP92309546 A EP 92309546A EP 0539141 A1 EP0539141 A1 EP 0539141A1
Authority
EP
European Patent Office
Prior art keywords
container
specimen
cap
main body
opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92309546A
Other languages
German (de)
English (en)
French (fr)
Inventor
Yukio Hamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Publication of EP0539141A1 publication Critical patent/EP0539141A1/en
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs

Definitions

  • the present invention relates to a container for a liquid specimen such as blood, urine or the like which is used in the field of clinical examination or the like.
  • the specimen in the container Before presenting (supplying) the liquid specimen to the analyzer, the specimen in the container must be stirred uniformly.
  • agitation by tumbling (inverting) is generally used.
  • the specimen in the container is small in quantity, the motion of the specimen in the container is excessive, and the specimen (such as blood) may be damaged.
  • the specimen such as blood
  • the size of the container may differ for each specimen, which is inconvenient for feeding (supplying) automatically to the automatic analyzer. It hence gives rise to a need for a container for liquid specimen small only in the internal volume, while the external shape is the same as an ordinary container for liquid specimen.
  • Japanese Laid-open Utility Model Hei. 2-27565 discloses accommodating a container of small volume (a test tube) inside a container of large volume, when using a small volume of reagent, but it relates to a container for reagent for handling different amounts of reagents on the same turn-table, and not to a container for a liquid specimen.
  • a container for a liquid specimen comprising a cap and a container main body having a specimen cavity which is openable and closable by the cap, wherein the bottom of the specimen cavity is disposed towards the middle of the main body.
  • the container is easy to use in both open and closed systems, and can be handled in the same way as an ordinary container.
  • the cap includes a circumferentially extending cover part for covering the upper end of the container main body, and an elastically deformable member located in an opening in the upper surface of the cap so as to close the opening.
  • a downwardly extending specimen adhering part is disposed at a position offset from the middle of the opening containing the elastically deformable member, the specimen adhering part may be used to smear specimen on a slide glass or the like.
  • the offset of the specimen adhering part it will not obstruct the sampling needle of a closed system particle analyzer or the like.
  • the container main body comprises a tubular body made of transparent material and a light shielding part for use in detecting the presence of the container, the light shielding part being disposed at the lower end of the tubular body.
  • the light shielding part attenuates the quantity of light reaching a detector so as to permit the optical detection of the difference between the presence and absence of the container.
  • the container of the invention is usable in a closed system when the cap is attached, and usable in an open system when the cap is detached.
  • a fine tube e.g. a syringe needle
  • pierces the elastically deformable member and aspirates the specimen.
  • the open system the cap is removed, and a specimen aspiration pipe is inserted into the upper opening of the container main body, and the specimen in the container is aspirated.
  • the embodiment comprises, as shown in Fig. 1, a container for liquid specimen comprising a cap 10, and a tubular container main body 12.
  • the cap 10 is made of synthetic resin, and has an elastic soft member 22 made of rubber.
  • the container main body 12 is made of transparent glass or transparent synthetic resin.
  • the rubber material of the elastic soft member 22 (also called rubber member 22) is fitted in an opening 20 provided in the centre of the cap and held in place by projections (clipping pieces) 30, 32.
  • projections (clipping pieces) 30, 32 When the cap 10 is screwed onto the container main body 10, the projection 32 of the rubber member is located between the main part of the cap 10 and the container main body 12, and the inside of the container is kept airtight.
  • the container In the case of a closed system, the container is kept airtight by the cap 10 and is repeatedly tumbled to stir the contents. Then, with the cap 10 facing downwards, a fine tube (a syringe needle) for aspirating the specimen is pushed through the central part of the rubber member 22, so that the specimen in the container is aspirated.
  • a fine tube a syringe needle
  • the cap 10 is manually detached from the container main body 12, and the specimen aspiration pipe is inserted in the upper opening, and the specimen is aspirated.
  • the rubber member 22 has a annular skirt 33 extending downwards so as to abut tightly against the upper inner wall of the container main body 12 when the cap 10 is attached to the container main body 12. From the lower end of the skirt 33, there projects a specimen adhering part 34 to which a small amount of specimen adheres.
  • the lower end part 36 of the specimen adhering part 34 is slightly broadened (see Fig. 3). This is intended to increase the surface area and increase the amount of specimen that adheres.
  • the area of the lower end part 36 may be adjusted to suit particular requirements.
  • a specimen groove may be provided at the lower end of the specimen adhering part 34.
  • the cap 10 When preparing a smeared specimen, the cap 10 is turned by hand and detached from the container main body 12, and the specimen adhered to the specimen adhering part 34 is deposited on a slide glass plate. Because of the cover part 18, the specimen does not come in contact with the user's hand when the user detaches the cap 10.
  • the specimen adhering part 34 is offset from the centre of the cap 10 and points directly downwards, it does not get in the way when piercing the rubber member 22 with the fine tube (syringe needle) in a closed system.
  • a light shielding part 28 extends around the lower part of the tubular body 16 of the container main body 12.
  • Symbols P, D are respectively a light emitting device such as a light emitting diode, and a photo detector such as a photo transistor.
  • the light shielding part 28 attenuates (decreases) the light passing across the detection region between the light emitting device P and photo detector D.
  • Any material that scatters light may be used.
  • the material may be ground (frosted) glass or may be coloured (for example, red).
  • the container of the invention has, so to speak, a raised bottom 14 of the internal cavity, and the volume for accommodating the specimen is smaller than for a conventional container.
  • the tubular body 16 may have the conventional external dimensions, and therefore the overall dimensions of the container of the invention may be the same as those of a conventional container.
  • the presence or absence of the container may be detected by the presence or absence of the transmission of light as disclosed in Japanese Laid-open Utility Model Sho. 63-141455.
  • the presence of a container is detected.
  • the presence of specimen in the container is also detected. Without the light shielding part 28, however, the light passes through the tubular body 16 and reaches the photo detector, and it is judged that the container is absent. In the case of a conventional container, since the light is refracted by the curved portion of the container bottom, the light does not reach the photo detector.
  • specimen adhering part 34 Specimen sticks to the specimen adhering part 34. Accordingly, by removing the cap 10 and causing the lower end of the specimen adhering part 34 to touch a slide glass, the specimen may be deposited on the slide glass. Hence, a smeared specimen may be prepared. Since the specimen adhering part 34 is offset from the centre of the cap, it does not interfere with the sampling tube of a closed system analyzer, unlike the projection of Japanese Laid-open Patent Hei. 1-219561.
  • the above embodiment of the container for a liquid specimen has the following characteristics.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
EP92309546A 1991-10-22 1992-10-20 Container for a liquid specimen Withdrawn EP0539141A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9447991U JPH0536364U (ja) 1991-10-22 1991-10-22 検体容器
JP94479/91 1991-10-22

Publications (1)

Publication Number Publication Date
EP0539141A1 true EP0539141A1 (en) 1993-04-28

Family

ID=14111417

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92309546A Withdrawn EP0539141A1 (en) 1991-10-22 1992-10-20 Container for a liquid specimen

Country Status (4)

Country Link
EP (1) EP0539141A1 (ja)
JP (1) JPH0536364U (ja)
AU (1) AU2713592A (ja)
CA (1) CA2080928A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034381A2 (en) * 1994-06-14 1995-12-21 Samco Scientific Inc. Perforable cap for a biological specimen container
DE9418060U1 (de) * 1994-11-11 1996-03-14 Sc Sanguis Counting Kontrollbl Probenröhre und Abschlußkappe, insesondere für Kapillar-Blutentnahme
WO1997012681A1 (en) * 1995-10-02 1997-04-10 Analyte Diagnostics, Inc. Sample collection, recovery and dispensing device for saliva
WO2014064548A1 (en) 2012-10-23 2014-05-01 Copan Italia S.P.A. A closing element of a container for biological fluids
US8747381B2 (en) 2007-07-12 2014-06-10 Sysmex Corporation Specimen container
CN113184356A (zh) * 2021-03-16 2021-07-30 李亚峰 一种密封性好的炎症生化检测试剂盒

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5506168B2 (ja) * 2008-08-04 2014-05-28 村角工業株式会社 検体収容容器
JP5484849B2 (ja) * 2009-09-30 2014-05-07 シスメックス株式会社 血液試料処理装置及び血液試料処理方法
JP5735361B2 (ja) 2010-08-02 2015-06-17 シスメックス株式会社 検体処理装置
JP5699235B2 (ja) * 2014-02-20 2015-04-08 シスメックス株式会社 血液試料処理装置及び血液試料処理方法
WO2019050802A1 (en) * 2017-09-05 2019-03-14 Beckman Coulter, Inc. COLLECTION AND PREPARATION OF BLOOD SAMPLES FOR INTERVENTION DIAGNOSES
CN210401441U (zh) * 2018-04-24 2020-04-24 深圳市帝迈生物技术有限公司 全自动进样血细胞分析测量装置及末梢血试管
CN111366738A (zh) * 2018-12-26 2020-07-03 北京普利生仪器有限公司 一种体外诊断设备及进样方法、适配器

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH330179A (de) * 1954-12-13 1958-05-31 Paul Dr Med Boettger Verfahren zum Verpacken von medizinischem Untersuchungsmaterial sowie Behälter zur Durchführung des Verfahrens
FR2339851A1 (fr) * 1976-01-29 1977-08-26 Siemens Ag Tube d'essai pour des echantillons de liquides
DE2813680B1 (de) * 1978-03-30 1979-06-13 Sarstedt Kunststoff Halter fuer eine Kapillare zur Aufnahme einer Blutprobe
JPH01219561A (ja) * 1988-02-26 1989-09-01 Terumo Corp 栓体およびそれを備えた試料採取用管体
EP0383262A2 (en) * 1989-02-13 1990-08-22 Terumo Kabushiki Kaisha Liquid collection tube
US4980129A (en) * 1989-12-22 1990-12-25 Eastman Kodak Company Kit of collection vessels of uniform outside dimensions, different volumes
EP0448795A2 (en) * 1990-03-29 1991-10-02 Becton, Dickinson and Company Compartmental body fluid collection tube

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH330179A (de) * 1954-12-13 1958-05-31 Paul Dr Med Boettger Verfahren zum Verpacken von medizinischem Untersuchungsmaterial sowie Behälter zur Durchführung des Verfahrens
FR2339851A1 (fr) * 1976-01-29 1977-08-26 Siemens Ag Tube d'essai pour des echantillons de liquides
DE2813680B1 (de) * 1978-03-30 1979-06-13 Sarstedt Kunststoff Halter fuer eine Kapillare zur Aufnahme einer Blutprobe
JPH01219561A (ja) * 1988-02-26 1989-09-01 Terumo Corp 栓体およびそれを備えた試料採取用管体
EP0383262A2 (en) * 1989-02-13 1990-08-22 Terumo Kabushiki Kaisha Liquid collection tube
US4980129A (en) * 1989-12-22 1990-12-25 Eastman Kodak Company Kit of collection vessels of uniform outside dimensions, different volumes
EP0448795A2 (en) * 1990-03-29 1991-10-02 Becton, Dickinson and Company Compartmental body fluid collection tube

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 13, no. 533 (P-967)28 November 1989 & JP-A-01 219 561 ( TERUMO CORP ) 1 September 1989 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034381A2 (en) * 1994-06-14 1995-12-21 Samco Scientific Inc. Perforable cap for a biological specimen container
WO1995034381A3 (en) * 1994-06-14 1996-04-04 Samco Scient Inc Perforable cap for a biological specimen container
DE9418060U1 (de) * 1994-11-11 1996-03-14 Sc Sanguis Counting Kontrollbl Probenröhre und Abschlußkappe, insesondere für Kapillar-Blutentnahme
WO1997012681A1 (en) * 1995-10-02 1997-04-10 Analyte Diagnostics, Inc. Sample collection, recovery and dispensing device for saliva
US8747381B2 (en) 2007-07-12 2014-06-10 Sysmex Corporation Specimen container
WO2014064548A1 (en) 2012-10-23 2014-05-01 Copan Italia S.P.A. A closing element of a container for biological fluids
CN113184356A (zh) * 2021-03-16 2021-07-30 李亚峰 一种密封性好的炎症生化检测试剂盒

Also Published As

Publication number Publication date
JPH0536364U (ja) 1993-05-18
CA2080928A1 (en) 1993-04-23
AU2713592A (en) 1993-04-29

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