EP0517606A2 - Verfahren und Vorrichtung zur Einführung von keimfreien Artikeln in einen keimfreien Raum - Google Patents

Verfahren und Vorrichtung zur Einführung von keimfreien Artikeln in einen keimfreien Raum Download PDF

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Publication number
EP0517606A2
EP0517606A2 EP92401556A EP92401556A EP0517606A2 EP 0517606 A2 EP0517606 A2 EP 0517606A2 EP 92401556 A EP92401556 A EP 92401556A EP 92401556 A EP92401556 A EP 92401556A EP 0517606 A2 EP0517606 A2 EP 0517606A2
Authority
EP
European Patent Office
Prior art keywords
guide tube
receptacle
door
objects
sterile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92401556A
Other languages
English (en)
French (fr)
Other versions
EP0517606A3 (en
Inventor
Bernard Saint Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iso Concept SA
Original Assignee
Iso Concept SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iso Concept SA filed Critical Iso Concept SA
Publication of EP0517606A2 publication Critical patent/EP0517606A2/de
Publication of EP0517606A3 publication Critical patent/EP0517606A3/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/02—Air-pressure chambers; Air-locks therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G10/00—Treatment rooms or enclosures for medical purposes
    • A61G10/005—Isolators, i.e. enclosures generally comprising flexible walls for maintaining a germ-free environment
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
    • F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
    • F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
    • F24F3/167—Clean rooms, i.e. enclosed spaces in which a uniform flow of filtered air is distributed

Definitions

  • the invention relates to a method and a device for introducing sterile objects, initially contained in sachets, into a clean volume under overpressure such as a sealed insulator.
  • Certain medical treatments require placing the patients in a sterile atmosphere delimited by a sealed isolator or by any other confinement enclosure.
  • this atmosphere is generally at overpressure relative to the outside.
  • the subject of the invention is precisely a method and a device making it possible to introduce sterile bagged objects inside a clean volume under overpressure in a much faster manner than with the procedure currently used and without the sterile nature of the objects and the atmosphere in the insulator are unaffected.
  • the receptacle is articulated about a horizontal axis orthogonal to a longitudinal axis of the guide tube, so that it can be moved between a horizontal position for receiving a bagged object and a tilted position for introducing the object into the guide tube, in which the receptacle is substantially aligned with a bottom wall of the guide tube.
  • a surface for receiving objects in the clean volume can also be provided, immediately below the lower end of the guide tube, beyond the door.
  • the stop means comprise a retractable lug, mounted on an upper wall of the guide tube, and the door is articulated around a horizontal upper axis, so as to be able to tilt towards the inside the clean volume when it is opened.
  • Means for cutting the sachets can also be mounted on the guide tube, near the receptacle.
  • the reference 10 designates a vertical wall of a sealed containment isolator, the sterile interior volume 12 of which is kept under overpressure by a conventional ventilation circuit (not shown).
  • a device allowing rapid insertion of sterile objects inside the volume 12 is installed on the wall 10.
  • a window 14, of rectangular shape is formed in the vertical wall 10, so that the peripheral edges of a rectangular plate 16 of the device for introducing sterile objects according to the invention are tightly fixed in this opening 14.
  • the rectangular plate 16 is deformed towards the outside of the insulator in its central part, to form a protuberance 16a, of generally circular vertical section, in which is housed a circular door 18 provided with an annular seal 20.
  • Gate 18 normally occupies a closed position, in which the seal 20 is in leaktight contact against the flat bottom 16b of the protrusion 16a of the plate 16, so as to close a rectangular opening 22 formed in this bottom 16b.
  • the door 18 comprises a yoke 24 to which is fixed a horizontal pivot axis 26, rotatably mounted in a projection formed at the upper part of the protuberance 16a.
  • the axis 26 is fixed to a first end of a lever 28, the opposite end of which is articulated on the rod 30 of a jack 32 by an axis 29 parallel to the axis 26.
  • the opposite end of the body of the jack 32 is articulated by a pin 34 on a frame 36, by which the device according to the invention rests on the ground.
  • the chassis 36 of the device for introducing sterile objects according to the invention also supports an inclined guide tube 38, of rectangular section, of which a lower outlet end is tightly connected, for example by welding, to the rectangular opening. 22 formed in the bottom 16b of the protuberance of the plate 16.
  • the dimensions presented in section by the guide tube 38 are chosen so as to allow the passage through this tube of sterile objects to be introduced into the sealed volume 12, such as box B in Figure 1.
  • the inclination of the guide tube 38 is determined so that objects such as the box B can descend by gravity inside of the guide tube, from an upper end of the latter, open towards the outside, to its lower end connected to the rectangular opening 22.
  • the chassis 36 of the insertion device supports a receptacle 40, constituted by a shelf which normally occupies the horizontal position illustrated in FIG. 1.
  • the upper plane of the tablet forming the receptacle 40 is located approximately halfway up the open upper end of the guide tube 38. This horizontal position of the tablet is obtained when the latter rests on supports 41 of the chassis 36.
  • the shelf forming the receptacle 40 has oblong holes 42 which pass through a horizontal axis 44 carried by the frame 36, in a direction orthogonal to the longitudinal axis of the guide tube 38.
  • the oblong holes 42 are also oriented horizontally and the axis 44 is in the part of the holes 42 closest to the upper end of the guide tube 38.
  • the tablet forming the receptacle 40 In its part furthest from the guide tube 38, the tablet forming the receptacle 40 is provided with an operating handle 46 allowing a user to tilt the tablet around the axis 44 and to slide it so that this axis approaches the opposite ends of the oblong holes 42. In the corresponding position, determined by the abutment of the tablet against a stop 48 formed on the frame 36, the upper face of the tablet forming the receptacle 40 is substantially in the extension of the lower wall of the guide tube 38 and at a lesser distance from this wall. The tilting of the tablet forming the receptacle 40 makes it possible to descend by gravity into the guide tube 38 an object such as the box B, previously placed on the tablet.
  • this retractable lug 50 is constituted by the folded down end of a plate 52, the opposite end of which is mounted on a rod 54 slidingly passing through the upper wall of the tube guide 38 in a direction perpendicular to this wall.
  • a compression spring 56 is interposed between the opposite end of the rod 54 and a cup 58 carried by a support 60 fixed on the upper wall of the guide tube 38, outside of the latter. This spring 56 normally maintains the lug 50 in its active position illustrated in FIGS. 1 and 2, in which this lug is in the path of an object such as the box B descending in the guide tube 38, so that it immobilizes this object before it reaches door 18.
  • a link 62 is pivotally mounted on the support 60, around an axis 64 oriented parallel to the horizontal axis of the guide tube 38.
  • One end of the link 62 has a fork which overlaps a finger 66 carried by the rod 54, while the opposite end of the link 62 is located opposite a protuberance 68 formed on the lever 28.
  • the device for introducing sterile objects further comprises a ventilation cabinet 70 which makes it possible to inject clean or sterile air inside the guide tube 38.
  • the ventilation cabinet 70 communicates with a pipe 72, of relatively large section, opening on the lower wall of the guide tube 38, in the immediate vicinity of the door 18.
  • a pipe 74 of smaller section is connected in branch on the pipe 72 and connected on the lower wall of the guide tube 38, in the immediate vicinity of the open upper end of the latter.
  • the device for introducing sterile objects further comprises a system for cutting the bag in which there are one or more objects to be inserted inside the 'insulator, when this object is placed on the tablet forming the receptacle 40.
  • This cutting system which is interposed between the open upper end of the guide tube 38 and the shelf forming the receptacle 40, comprises a horizontal upper support plate 76 fixed on the open upper end of the guide tube 38, in the part superior of the latter.
  • a horizontal lower support plate 78 is mounted below the horizontal upper support plate 76 on the vertical rod 80 of a jack 82 whose body is fixed to the chassis 36.
  • An actuation of the jack 82 in the direction of elongation thus has the effect of applying the lower support plate 78 against the upper support plate 76. If a sterile object such as box B, packed in a sachet, is placed on the tablet forming the receptacle 40, the edge of the bag is therefore pinched between the support plates 76 and 78.
  • the guide tube 38 also supports two horizontal columns 84 which are oriented parallel to the adjacent edges of the shelf forming the receptacle 40 and of the open upper end of the guide tube 38.
  • a slide 86 capable of being maneuvered by a handle 88, is slidably mounted on the balusters 84.
  • This slide 86 supports a cutting wheel 90 about an horizontal axis orthogonal to the axes of the columns 84.
  • the cutting wheel 90 is arranged such that it is permanently flush with an edge of the upper support plate 76, while projecting slightly below the latter in a slot formed for this purpose in the lower support plate 78, in line with the dial 90.
  • the door 18 normally occupies its closed position preserving the confinement of the volume 12 vis-à-vis the external atmosphere.
  • the lug 50 is then in the active position in the guide tube 38.
  • the ventilation cabinet 70 is permanently actuated.
  • the edge of the bag S adjacent to the open end of the guide tube 38 can therefore be cut using the knurled wheel 90, after actuation of the jack 82 (FIG. 1), without the the sterile nature of box B is disturbed.
  • the device for introducing sterile objects according to the invention makes it possible to introduce these objects in a particularly rapid manner, without, however, the sterile nature of these objects or the cleanliness of the room in which they are introduced and are not disturbed.
  • the invention is not limited to the embodiment which has just been described by way of example, but covers all its variants.
  • the cutting of the sachets in which the sterile objects which are to be introduced into the room are located can be carried out by cutting means not belonging to the device.
  • the lug making it possible to stop the fall of objects in the guide tube can be replaced by any other equivalent retractable stop system, for example pivoting, and the pivoting door 18 can be replaced, for example, by a sliding door. .

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Combustion & Propulsion (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Chutes (AREA)
  • Vacuum Packaging (AREA)
EP19920401556 1991-06-07 1992-06-05 Device and process to introduce sterile objects in a sterile space Withdrawn EP0517606A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9106945A FR2677245B1 (fr) 1991-06-07 1991-06-07 Procede et dispositif d'introduction d'objets steriles dans un volume propre.
FR9106945 1991-06-07

Publications (2)

Publication Number Publication Date
EP0517606A2 true EP0517606A2 (de) 1992-12-09
EP0517606A3 EP0517606A3 (en) 1993-02-10

Family

ID=9413602

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19920401556 Withdrawn EP0517606A3 (en) 1991-06-07 1992-06-05 Device and process to introduce sterile objects in a sterile space

Country Status (4)

Country Link
EP (1) EP0517606A3 (de)
JP (1) JPH05178460A (de)
CA (1) CA2070461A1 (de)
FR (1) FR2677245B1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997039327A1 (en) * 1996-04-15 1997-10-23 The Technology Partnership Plc Chemical sampling/dispensing apparatus
DE102022101774A1 (de) 2022-01-26 2023-07-27 Atec Pharmatechnik Gmbh Aufnahme-Port zum Übertragen von Gegenständen in einen Behälter sowie Rapid-Transfer-System mit einem Aufnahme-Port

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR772020A (fr) * 1933-07-17 1934-10-22 Roussel Uclaf Appareil pour le travail sous atmosphère neutre des substances altérables, telles que les substances organiques destinées à la préparation des cachets opothérapiques et similaires
FR1506930A (fr) * 1966-12-29 1967-12-22 Snyder Mfg Co Procédé et installation permettant d'isoler dans des conditions stériles une zone de son environnement
FR2366918A1 (fr) * 1976-10-11 1978-05-05 Usifroid Installation de traitements de produits conditionnes dans des recipients permettant le prelevement d'echantillons
US4111753A (en) * 1976-06-07 1978-09-05 National Appliance Company Controlled atmosphere apparatus and method of transferring specimens to same
EP0374047A1 (de) * 1988-12-15 1990-06-20 Iso Concept Vorrichtungen zur schnellen Aus- und Einführung von Gegenständen für einen nach aussen dicht abgeschlossenen Raum

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR772020A (fr) * 1933-07-17 1934-10-22 Roussel Uclaf Appareil pour le travail sous atmosphère neutre des substances altérables, telles que les substances organiques destinées à la préparation des cachets opothérapiques et similaires
FR1506930A (fr) * 1966-12-29 1967-12-22 Snyder Mfg Co Procédé et installation permettant d'isoler dans des conditions stériles une zone de son environnement
US4111753A (en) * 1976-06-07 1978-09-05 National Appliance Company Controlled atmosphere apparatus and method of transferring specimens to same
FR2366918A1 (fr) * 1976-10-11 1978-05-05 Usifroid Installation de traitements de produits conditionnes dans des recipients permettant le prelevement d'echantillons
EP0374047A1 (de) * 1988-12-15 1990-06-20 Iso Concept Vorrichtungen zur schnellen Aus- und Einführung von Gegenständen für einen nach aussen dicht abgeschlossenen Raum

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997039327A1 (en) * 1996-04-15 1997-10-23 The Technology Partnership Plc Chemical sampling/dispensing apparatus
DE102022101774A1 (de) 2022-01-26 2023-07-27 Atec Pharmatechnik Gmbh Aufnahme-Port zum Übertragen von Gegenständen in einen Behälter sowie Rapid-Transfer-System mit einem Aufnahme-Port
WO2023143679A1 (de) 2022-01-26 2023-08-03 Atec Pharmatechnik Gmbh Aufnahme-port zum übertragen von gegenständen in einen behälter sowie rapid-transfer-system mit einem aufnahme-port

Also Published As

Publication number Publication date
FR2677245B1 (fr) 1993-09-24
EP0517606A3 (en) 1993-02-10
JPH05178460A (ja) 1993-07-20
CA2070461A1 (en) 1992-12-08
FR2677245A1 (fr) 1992-12-11

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