EP0471323B1 - Nébulisateur pour médicaments liquides - Google Patents

Nébulisateur pour médicaments liquides Download PDF

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Publication number
EP0471323B1
EP0471323B1 EP91113500A EP91113500A EP0471323B1 EP 0471323 B1 EP0471323 B1 EP 0471323B1 EP 91113500 A EP91113500 A EP 91113500A EP 91113500 A EP91113500 A EP 91113500A EP 0471323 B1 EP0471323 B1 EP 0471323B1
Authority
EP
European Patent Office
Prior art keywords
nozzle
nebulizer
nebulizer according
annular gap
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP91113500A
Other languages
German (de)
English (en)
Other versions
EP0471323A1 (fr
Inventor
Waltraud Hecker
Ludwig Hallmannseder
Rudolf Schinagl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PARI GmbH Spezialisten fuer Effektive Inhalation
Original Assignee
PARI GmbH Spezialisten fuer Effektive Inhalation
PARI GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6856490&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0471323(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PARI GmbH Spezialisten fuer Effektive Inhalation, PARI GmbH filed Critical PARI GmbH Spezialisten fuer Effektive Inhalation
Publication of EP0471323A1 publication Critical patent/EP0471323A1/fr
Application granted granted Critical
Publication of EP0471323B1 publication Critical patent/EP0471323B1/fr
Anticipated expiration legal-status Critical
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/0012—Apparatus for achieving spraying before discharge from the apparatus

Definitions

  • the invention relates to a nebulizer device for the Nebulization of watery or oily medication at the Inhalation therapy with the characteristics of the generic term of the Claim 1.
  • a nebulizer device with these features is known from EP-A-0 261 649.
  • the atomizing nozzle is in one Inhalation therapy device integrated and in the bottom of a Storage container for the liquid arranged.
  • the Atomizer nozzle works on the Venturi principle and has plus a nozzle body with a nozzle opening at the top has that of a concentric, annular gap is surrounded.
  • the nozzle body also has channels through which the liquid from the reservoir to the ring-shaped Gap is suckable.
  • Embodiments adjusting means provided the distance adjustable between the surface and the nozzle openings do.
  • a nebulizer with a Venturi principle working nozzle is also known from EP-A-0 170 715. At This nozzle is next to the compressed gas channel arranged opposite two intake ducts. The Across from the nozzle openings is a air flow control extending the nozzle with a wedge-shaped Bottom.
  • nebulizers from US 3,762,409 and AU-B-483 193 are nebulizers with a mixing chamber, i.e. with a closed room above the compressed air nozzle opening in which the drug is sucked in and already partially nebulized. From the The aspirated medication joins the mixing chamber Compressed gas flow from a further opening that the Opposed nozzle opening for the compressed gas and which differs from outside as the only nozzle opening.
  • These nebulizers differ from the nebulizers described above due to the mixing chamber and due to the fact that after a nozzle opening appears on the outside.
  • nebulizers The different designs of the previously described The aim of nebulizers is always the best, i.e. to produce respiratory aerosol.
  • the invention also has the object to improve a liquid nebulizer so that Optimal particle sizes in the sense of fine atomization can be achieved.
  • a defined amount is one Inhale medication.
  • a maximum is achieved by the invention
  • the drug is nebulized so that the inhalation time is minimized.
  • Another Advantage of the invention is that the liquid through channels and thus regulated the gap is fed.
  • the liquid nebulizer shown in Figures 1 and 2 is part of a Handheld devices for inhalations.
  • the liquid nebulizer is inside a two-part housing, of which in Fig. 2 the reservoir 20 for the Liquid is shown.
  • the housing (otherwise not shown) faces below a hose for the supply of compressed air (not shown) and a top Mouthpiece (not shown) and is also with a known nebulizer button (not shown) equipped, at the pressure of which compressed air is actuated.
  • the liquid nebulizer consists of three parts, namely the nozzle body A, the Cylinder sleeve B and the attachment C. These parts are made by simple plug connections connected with each other.
  • the nozzle body A which is shown in FIG. 4, points downwards directed nozzle body extension 21 to which a compressed air line is connected becomes. In the area of the nozzle body extension 21, the nozzle body A is sealed passed through the bottom of the reservoir 20.
  • the nozzle body A has a central, through the entire nozzle body in Nozzle channel 1 running in the longitudinal direction.
  • the upper section of the Nozzle body A is in the form of a nozzle cone 4 with a nozzle tip 3 executed.
  • nozzle tip 3 In the middle of the nozzle tip 3, which is cylindrical on the outside, sits Nozzle opening 2.
  • the nozzle body A has ribs 5 on the outside, which together with the inner wall of the cylinder sleeve B form channels 7 in which the liquid is sucked from the reservoir to the gap 2a.
  • the cylinder sleeve B shown in FIGS. 5 and 6 has an outer cylinder surface 9.
  • the cylinder thus formed goes over a shoulder in the nozzle jacket 8 smaller diameter over.
  • the top of the Nozzle jacket is designed as a depression 14.
  • the cylinder ring 12 forms together with the nozzle tip 3 an annular gap 2a which the nozzle opening 2 with Distance concentrically surrounds.
  • the cylinder sleeve B ends at the bottom somewhat above the bottom of the storage container 20 so that an annular gap 6 is formed.
  • the attachment C has a cylinder 15 at the bottom, the wall thickness of which Dimension of the formed between the outer cylinder surface 9 and the nozzle jacket 8 Paragraph corresponds.
  • the cylinder 15 is provided with a baffle plate 16 via webs 19 connected.
  • the baffle plate 16 has a center against the nozzle opening 2 directed pin 17, which has a conical tip 18.
  • the height of the cylinder 15 is dimensioned so that its in the installed state Top is higher than the top of the nozzle shell 8.
  • the top of the Cylinder 15 is approximately at the height of the tip 18, the maximum distance is 0.2 mm.
  • the described device works as follows: If compressed air is passed through the nozzle channel 1, a negative pressure is created at the nozzle opening 2. The air is also swirled by deflecting the emerging air at the tip 18 of the pin 17 and at the baffle plate 16.

Landscapes

  • Nozzles (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Claims (10)

  1. Nébulisateur pour la nébulisation de médicaments liquides ou huileux, dans la thérapie par inhalation, avec une buse de pulvérisateur destinée à la sortie d'air comprimé, ce nébulisateur étant adapté à l'intégration dans un appareil de nébulisation réalisé en deux parties, dont la partie inférieure présente un réservoir de stockage (20) destiné au liquide, à travers le fond duquel le dispositif nébulisateur travaillant selon le principe du venturi est guidé de façon étanche, avec un corps de buse (A), présentant à l'extrémité supérieure une ouverture de buse (2) entourée par un intervalle annulaire (2a) concentrique et présentant des canaux (7) par l'intermédiaire desquels le liquide peut être aspiré du réservoir de stockage vers l'intervalle (2a), caractérisé en ce qu'une plaque d'impact (16), portant une tige (17) à pointe (18) conique et orientée vers l'ouverture de buse (2), est disposée en regard de l'ouverture de buse (2), à distance de celle-ci.
  2. Nébulisateur selon la revendication 1, caractérisé en ce que l'intervalle annulaire (2a) est constitué par la pointe de buse (3) et une enveloppe de buse (8), et en ce que l'enveloppe de buse (8) constitue la partie supérieure d'une douille cylindrique (B) entourant le corps de buse (A).
  3. Nébulisateur selon la revendication 2, caractérisé en ce que la douille cylindrique (B) est montée sur des nervures extérieures (5) appartenant au corps de buse (A), en formant un intervalle annulaire inférieur (6) servant d'ouverture d'accès au réservoir de stockage (20), et en ce que les canaux (7) menant à l'intervalle annulaire (2a) sont constitués par les nervures (5) et la paroi intérieure de la douille cylindrique (B).
  4. Nébulisateur selon l'une des revendications 1 à 3, caractérisé en ce que le diamètre de la tige (17) correspond au diamètre extérieur de l'intervalle annulaire (2a).
  5. Nébulisateur selon l'une des revendications 2 à 4, caractérisé en ce que la face supérieure de l'enveloppe de buse (8) est réalisée sous la forme de creusement (14) dont le point le plus bas est situé dans le plan de l'ouverture de buse (2) ou bien au-dessus.
  6. Nébulisateur selon l'une des revendications 2 à 5, caractérisé en ce que sur la douille cylindrique (B) est monté un cylindre (15), relié par des nervures (19), à la plaque d'impact (16) et constituant avec celle-ci un ensemble (chapeau ou élément rapporté C).
  7. Nébulisateur selon la revendication 6, caractérisé en ce que l'arête supérieure du cylindre (15) est disposée à une distance maximale de 0,2 mm de la pointe (18) de la tige (17).
  8. Nébulisateur selon l'une des revendications 1 à 7, caractérisé en ce que le cône constituant la pointe (18) a un angle de pointe de 140-160°.
  9. Nébulisateur selon l'une des revendications 1 à 8, caractérisé en ce que le fond du récipient à liquide (20) va en descendant en allant vers le centre.
  10. Nébulisateur selon l'une des revendications 1 à 9, caractérisé en ce qu'il est formé par emboítement de pièces en matière plastique.
EP91113500A 1990-08-13 1991-08-12 Nébulisateur pour médicaments liquides Expired - Lifetime EP0471323B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE9011768U DE9011768U1 (fr) 1990-08-13 1990-08-13
DE9011768U 1990-08-13

Publications (2)

Publication Number Publication Date
EP0471323A1 EP0471323A1 (fr) 1992-02-19
EP0471323B1 true EP0471323B1 (fr) 1999-12-01

Family

ID=6856490

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91113500A Expired - Lifetime EP0471323B1 (fr) 1990-08-13 1991-08-12 Nébulisateur pour médicaments liquides

Country Status (4)

Country Link
EP (1) EP0471323B1 (fr)
JP (1) JPH04244168A (fr)
AT (1) ATE187084T1 (fr)
DE (2) DE9011768U1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547292B2 (en) 2001-01-11 2009-06-16 Powderject Research Limited Needleless syringe
US8540665B2 (en) 2007-05-04 2013-09-24 Powder Pharmaceuticals Inc. Particle cassettes and processes therefor

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114080D0 (en) * 1991-06-28 1991-08-14 Weston Terence E Atomising valve
DE9113446U1 (fr) * 1991-10-29 1992-01-16 Kendall Medizinische Erzeugnisse Gmbh, 8425 Neustadt, De
GB9311614D0 (en) * 1993-06-04 1993-07-21 Aid Medic Ltd Nebulizer
US5875774A (en) * 1996-01-05 1999-03-02 Sunrise Medical Hhg Inc. Nebulizer
EP1896188B1 (fr) 2005-06-29 2010-08-18 Boehringer Ingelheim International GmbH Procede et dispositif d'atomisation de liquide
EP2608829A4 (fr) 2010-08-23 2015-11-18 Darren Rubin Systèmes et procédés d'administration d'un aérosol avec régulation du flux d'air
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
CN109172965A (zh) * 2018-10-24 2019-01-11 威海盛洁医疗科技有限公司 一种雾化颗粒大小可调节的雾化杯

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE100333C (fr) *
DE1006354B (de) * 1954-03-19 1957-04-11 Paul Tegtmeier Fluessigkeitsbrause
US3762409A (en) * 1970-11-03 1973-10-02 V Lester Nebulizer
AU483193B2 (en) * 1975-12-03 1976-02-26 Hudson Oxygen Therapy Sales Company A nebulizer
DE3470380D1 (en) * 1984-08-09 1988-05-19 Inge Brugger Nebulizer
ES2029248T3 (es) * 1986-09-22 1992-08-01 Omron Tateisi Electronics Co. Pulverizador.

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7547292B2 (en) 2001-01-11 2009-06-16 Powderject Research Limited Needleless syringe
USRE43824E1 (en) 2001-01-11 2012-11-20 Powder Pharmaceuticals Inc. Needleless syringe
US8540665B2 (en) 2007-05-04 2013-09-24 Powder Pharmaceuticals Inc. Particle cassettes and processes therefor
US9044546B2 (en) 2007-05-04 2015-06-02 Powder Pharmaceuticals Incorporated Particle cassettes and processes therefor
US9358338B2 (en) 2007-05-04 2016-06-07 Powder Pharmaceuticals Incorporated Particle cassettes and processes therefor

Also Published As

Publication number Publication date
EP0471323A1 (fr) 1992-02-19
DE9011768U1 (fr) 1990-11-08
ATE187084T1 (de) 1999-12-15
JPH04244168A (ja) 1992-09-01
DE59109170D1 (de) 2000-01-05

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