EP0471323A1 - Nébulisateur pour médicaments liquides - Google Patents

Nébulisateur pour médicaments liquides Download PDF

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Publication number
EP0471323A1
EP0471323A1 EP91113500A EP91113500A EP0471323A1 EP 0471323 A1 EP0471323 A1 EP 0471323A1 EP 91113500 A EP91113500 A EP 91113500A EP 91113500 A EP91113500 A EP 91113500A EP 0471323 A1 EP0471323 A1 EP 0471323A1
Authority
EP
European Patent Office
Prior art keywords
nozzle
nebulizer
tip
gap
cylinder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP91113500A
Other languages
German (de)
English (en)
Other versions
EP0471323B1 (fr
Inventor
Waltraud Hecker
Ludwig Hallmannseder
Rudolf Schinagl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PARI GmbH Spezialisten fuer Effektive Inhalation
Original Assignee
PAUL RITZAU PARI-WERK GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6856490&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0471323(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PAUL RITZAU PARI-WERK GmbH filed Critical PAUL RITZAU PARI-WERK GmbH
Publication of EP0471323A1 publication Critical patent/EP0471323A1/fr
Application granted granted Critical
Publication of EP0471323B1 publication Critical patent/EP0471323B1/fr
Anticipated expiration legal-status Critical
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/0012Apparatus for achieving spraying before discharge from the apparatus

Definitions

  • the invention relates to a liquid nebulizer for nebulizing aqueous or oily medications during inhalation therapy with an atomizing nozzle for the discharge of compressed air, this nebuliser being intended for installation in a two-part nebulizing device, the lower part of which has a storage container for the liquid through the bottom thereof sealed the liquid nebulizer working on the Venturi principle is guided.
  • the invention has for its object to improve a liquid nebulizer so that optimal particle sizes are achieved in the sense of a fine atomization.
  • a nozzle body at the upper end has a nozzle opening which is surrounded by a concentric, annular gap which is connected to the storage container via channels, and that is at a distance from the nozzle opening a baffle plate is arranged, which carries a pin directed against the nozzle opening with a conical tip.
  • Negative pressure is generated by the compressed air flowing out of the nozzle opening.
  • liquid emerges from the annular gap, which is carried away by the rapidly flowing air and broken down into the finest drops rotating around its center, which burst further due to their high speed and form even smaller droplets.
  • This effect is further increased by the arrangement of the pin with the conical tip and by the baffle plate, because this creates a swirling of the stream consisting of compressed air and atomized liquid which is important for the atomization.
  • a defined amount of a medication must be inhaled for the treatment of respiratory diseases.
  • a maximum of medication is atomized by the invention, so that the inhalation time is minimized.
  • Another advantage of the invention is that the liquid is supplied to the gap through channels and thus in a controlled manner.
  • the liquid nebulizer shown in Figures 1 and 2 is part of a hand-held device for inhalations.
  • the liquid nebulizer is located within a two-part housing, of which the reservoir 20 for the liquid is shown in FIG. 2.
  • the housing (not shown in the rest) has a hose for the supply of compressed air (not shown) and a mouthpiece (not shown) at the top and is also equipped with a known nebulizer button (not shown), at the pressure of which the compressed air is operated becomes.
  • the liquid nebulizer consists of three parts, namely the nozzle body A, the cylinder sleeve B and the attachment C. These parts are connected to one another by simple plug connections.
  • the nozzle body A which is shown in FIG. 4, has a downwardly directed nozzle body extension 21 to which a compressed air line is connected. In the area of the nozzle body extension 21, the nozzle body A is guided through the bottom of the storage container 20 in a sealed manner.
  • the nozzle body A has a central nozzle channel 1 which runs in the longitudinal direction through the entire nozzle body.
  • the upper section of the nozzle body A is designed in the form of a nozzle cone 4 with a nozzle tip 3.
  • the nozzle opening 2 sits in the center of the nozzle tip 3, which is cylindrical on the outside.
  • the nozzle body A has ribs 5 on the outside, which together with the inner wall of the cylinder sleeve B form channels 7 in which the Liquid is sucked from the reservoir to the gap 2a.
  • the cylinder sleeve B shown in FIGS. 5 and 6 has an outer cylinder surface 9.
  • the cylinder formed in this way passes over a shoulder into the nozzle jacket 8 of smaller diameter.
  • the top of the nozzle jacket is designed as a depression 14.
  • the cylinder ring 12 forms together with the nozzle tip 3 an annular gap 2a which concentrically surrounds the nozzle opening 2 at a distance.
  • the cylinder sleeve B ends at the bottom somewhat above the bottom of the storage container 20, so that an annular gap 6 is formed.
  • the attachment C has a cylinder 15 at the bottom, the wall thickness of which corresponds to the dimension of the shoulder formed between the cylinder outer surface 9 and the nozzle jacket 8.
  • the cylinder 15 is connected to a baffle plate 16 via webs 19.
  • the baffle plate 16 has a pin 17, which is directed towards the nozzle opening 2 and has a conical tip 18.
  • the height of the cylinder 15 is dimensioned such that, in the installed state, its top is higher than the top of the nozzle jacket 8.
  • the top of the cylinder 15 is approximately at the height of the tip 18, a maximum distance of 0.2 mm should be provided.
  • the device described works as follows: If compressed air is passed through the nozzle channel 1, a negative pressure is created at the nozzle opening 2. The air is also swirled by deflecting the emerging air at the tip 18 of the pin 17 and at the baffle plate 16.
  • the effect of the Venturi principle is optimally used. This effect is further increased by the fact that the top of the nozzle jacket 8 is designed as a depression 14 and that the tip 18 has a tip angle of 140-160.

Landscapes

  • Nozzles (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
EP91113500A 1990-08-13 1991-08-12 Nébulisateur pour médicaments liquides Expired - Lifetime EP0471323B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE9011768U 1990-08-13
DE9011768U DE9011768U1 (de) 1990-08-13 1990-08-13 Flüssigkeitsvernebler für Medikamente

Publications (2)

Publication Number Publication Date
EP0471323A1 true EP0471323A1 (fr) 1992-02-19
EP0471323B1 EP0471323B1 (fr) 1999-12-01

Family

ID=6856490

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91113500A Expired - Lifetime EP0471323B1 (fr) 1990-08-13 1991-08-12 Nébulisateur pour médicaments liquides

Country Status (4)

Country Link
EP (1) EP0471323B1 (fr)
JP (1) JPH04244168A (fr)
AT (1) ATE187084T1 (fr)
DE (2) DE9011768U1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370317A (en) * 1991-06-28 1994-12-06 Glaxo Group Limited Atomizing device for producing a spray from a liquid under pressure
EP0627266A2 (fr) * 1993-06-04 1994-12-07 Medic-Aid Limited Nébuliseur
US5875774A (en) * 1996-01-05 1999-03-02 Sunrise Medical Hhg Inc. Nebulizer
WO2007000330A2 (fr) 2005-06-29 2007-01-04 Boehringer Ingelheim International Gmbh Procede et dispositif d'atomisation de liquide
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
CN109172965A (zh) * 2018-10-24 2019-01-11 威海盛洁医疗科技有限公司 一种雾化颗粒大小可调节的雾化杯
EP3950028A1 (fr) 2010-08-23 2022-02-09 Darren Rubin Systèmes et procédés d'administration d'un aérosol avec régulation du flux d'air

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9113446U1 (de) * 1991-10-29 1992-01-16 Kendall Medizinische Erzeugnisse GmbH, 8425 Neustadt Handvernebler für das Zerstäuben von therapeutischen Flüssigkeiten
GB0100756D0 (en) 2001-01-11 2001-02-21 Powderject Res Ltd Needleless syringe
GB0708758D0 (en) 2007-05-04 2007-06-13 Powderject Res Ltd Particle cassettes and process thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE100333C (fr) *
DE1006354B (de) * 1954-03-19 1957-04-11 Paul Tegtmeier Fluessigkeitsbrause
US3762409A (en) * 1970-11-03 1973-10-02 V Lester Nebulizer
AU483193B2 (en) * 1975-12-03 1976-02-26 Hudson Oxygen Therapy Sales Company A nebulizer
EP0170715A1 (fr) * 1984-08-09 1986-02-12 Inge Brugger Dispositif de pulvérisation
EP0261649A2 (fr) * 1986-09-22 1988-03-30 Omron Tateisi Electronics Co. Nébuliseur

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE100333C (fr) *
DE1006354B (de) * 1954-03-19 1957-04-11 Paul Tegtmeier Fluessigkeitsbrause
US3762409A (en) * 1970-11-03 1973-10-02 V Lester Nebulizer
AU483193B2 (en) * 1975-12-03 1976-02-26 Hudson Oxygen Therapy Sales Company A nebulizer
EP0170715A1 (fr) * 1984-08-09 1986-02-12 Inge Brugger Dispositif de pulvérisation
EP0261649A2 (fr) * 1986-09-22 1988-03-30 Omron Tateisi Electronics Co. Nébuliseur

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370317A (en) * 1991-06-28 1994-12-06 Glaxo Group Limited Atomizing device for producing a spray from a liquid under pressure
US5370318A (en) * 1991-06-28 1994-12-06 Glaxo Group Limited Atomizing nozzle for producing a spray from a liquid under pressure
EP0627266A2 (fr) * 1993-06-04 1994-12-07 Medic-Aid Limited Nébuliseur
EP0627266A3 (fr) * 1993-06-04 1995-09-13 Aid Medic Ltd Nébuliseur.
US5875774A (en) * 1996-01-05 1999-03-02 Sunrise Medical Hhg Inc. Nebulizer
WO2007000330A2 (fr) 2005-06-29 2007-01-04 Boehringer Ingelheim International Gmbh Procede et dispositif d'atomisation de liquide
US7611072B2 (en) 2005-06-29 2009-11-03 Boehringer Ingelheim International Gmbh Method and device for atomizing liquid
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
EP3950028A1 (fr) 2010-08-23 2022-02-09 Darren Rubin Systèmes et procédés d'administration d'un aérosol avec régulation du flux d'air
CN109172965A (zh) * 2018-10-24 2019-01-11 威海盛洁医疗科技有限公司 一种雾化颗粒大小可调节的雾化杯

Also Published As

Publication number Publication date
JPH04244168A (ja) 1992-09-01
DE9011768U1 (de) 1990-11-08
ATE187084T1 (de) 1999-12-15
EP0471323B1 (fr) 1999-12-01
DE59109170D1 (de) 2000-01-05

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