EP0423239A4 - Post-transfusion, non-a, non-b hepatitis virus and antigens - Google Patents

Post-transfusion, non-a, non-b hepatitis virus and antigens

Info

Publication number
EP0423239A4
EP0423239A4 EP19890909076 EP89909076A EP0423239A4 EP 0423239 A4 EP0423239 A4 EP 0423239A4 EP 19890909076 EP19890909076 EP 19890909076 EP 89909076 A EP89909076 A EP 89909076A EP 0423239 A4 EP0423239 A4 EP 0423239A4
Authority
EP
European Patent Office
Prior art keywords
transfusion
antigens
post
hepatitis virus
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890909076
Other languages
English (en)
Other versions
EP0423239A1 (en
Inventor
Gregory R. Reyes
Daniel W. Bradley
Linda Rabin
Kirk E. Fry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Genelabs Inc
Original Assignee
US Department of Health and Human Services
Genelabs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, Genelabs Inc filed Critical US Department of Health and Human Services
Publication of EP0423239A1 publication Critical patent/EP0423239A1/en
Publication of EP0423239A4 publication Critical patent/EP0423239A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24221—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP19890909076 1988-07-06 1989-06-28 Post-transfusion, non-a, non-b hepatitis virus and antigens Withdrawn EP0423239A4 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US21572888A 1988-07-06 1988-07-06
US22833488A 1988-08-04 1988-08-04
US228334 1988-08-04
US33470189A 1989-04-06 1989-04-06
US35057089A 1989-05-11 1989-05-11
US350570 1989-05-11
US334701 1994-11-04
US215728 2002-08-09

Publications (2)

Publication Number Publication Date
EP0423239A1 EP0423239A1 (en) 1991-04-24
EP0423239A4 true EP0423239A4 (en) 1992-05-20

Family

ID=27499018

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890909076 Withdrawn EP0423239A4 (en) 1988-07-06 1989-06-28 Post-transfusion, non-a, non-b hepatitis virus and antigens

Country Status (5)

Country Link
EP (1) EP0423239A4 (ja)
JP (1) JPH04501203A (ja)
CN (1) CN1041005A (ja)
AU (1) AU4046489A (ja)
WO (1) WO1990000597A1 (ja)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5191064A (en) * 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
WO1990011089A1 (en) * 1989-03-17 1990-10-04 Chiron Corporation Nanbv diagnostics and vaccines
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
US7166287B1 (en) 1989-12-18 2007-01-23 Glaxo Wellcome Inc. Viral agent
LU87861A1 (fr) 1989-12-18 1991-10-08 Wellcome Found Agent viral
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
US5747239A (en) * 1990-02-16 1998-05-05 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines
CA2079677A1 (en) * 1990-04-03 1991-10-04 Kenneth H. Burk Purified hcv and hcv proteins and peptides
US5712087A (en) * 1990-04-04 1998-01-27 Chiron Corporation Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens
ES2152922T3 (es) * 1990-04-06 2001-02-16 Genelabs Tech Inc Epitopos del virus de la hepatitis c.
CA2044296A1 (en) * 1990-06-12 1991-12-13 Hiroaki Okamoto Oligonucleotide primers, and their application for high-fidelity detection of non-a, non-b hepatitis virus
US5747339A (en) * 1990-06-25 1998-05-05 Research Foundation For Microbial Diseases Of Osaka Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide
EP0933426A1 (en) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides
CA2090335A1 (en) * 1990-08-25 1992-02-26 Suzanne Zebedee Non-a, non-b hepatitis virus antigen, diagnostic methods and vaccines
AU640569B2 (en) * 1991-03-26 1993-08-26 Dade International Inc. Assay for non-a non-b hepatitis
FR2677372B1 (fr) 1991-06-06 1994-11-10 Pasteur Institut Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.
US5866139A (en) * 1992-06-04 1999-02-02 Institut Pasteur Nucleotide and peptide sequences of a hepatitis C virus isolate, diagnostic and therapeutic applications
US5552310A (en) * 1992-06-12 1996-09-03 Hiroshi Yoshikura Replication of hepatitis C virus genome and identification of virus having high infectivity
US5859230A (en) * 1992-07-30 1999-01-12 Genelabs Technologies, Inc. Non-A/non-B/non-C/non-D/non-E hepatitis agents and molecular cloning thereof
JPH07504333A (ja) * 1992-12-29 1995-05-18 アクゾ・ノベル・エヌ・ベー Ｃ型肝炎ウイルスに対するモノクローナル抗体及び抗イディオタイプ抗体
AU6943994A (en) * 1993-05-04 1994-11-21 United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hepatitis c virus cell propagation and related methods
US6720166B2 (en) 1994-02-14 2004-04-13 Abbott Laboratories Non-a, non-b, non-c, non-c, non-d, non-e hepatitis reagents and methods for their use
US6451578B1 (en) 1994-02-14 2002-09-17 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US6558898B1 (en) 1994-02-14 2003-05-06 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US6051374A (en) * 1994-02-14 2000-04-18 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US5981172A (en) * 1994-02-14 1999-11-09 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
US5843450A (en) * 1994-02-14 1998-12-01 Abbott Laboratories Hepatitis GB Virus synthetic peptides and uses thereof
US6156495A (en) * 1994-02-14 2000-12-05 Abbott Laboratories Hepatitis GB virus recombinant proteins and uses thereof
US6586568B1 (en) 1994-02-14 2003-07-01 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US5824507A (en) * 1994-05-20 1998-10-20 Genelabs Technologies, Inc. Hepatitis G virus and molecular cloning thereof
US5874563A (en) * 1994-05-20 1999-02-23 Genelabs Technologies, Inc. Hepatitis G virus and molecular cloning thereof
PT763114E (pt) * 1994-05-20 2002-05-31 Genelabs Tech Inc Virus da hepatite g e sua clonagem molecular
US5709997A (en) * 1995-08-14 1998-01-20 Abbott Laboratories Nucleic acid detection of hepatitis GB virus
US5955318A (en) * 1995-08-14 1999-09-21 Abbott Laboratories Reagents and methods useful for controlling the translation of hepatitis GBV proteins
US5807670A (en) * 1995-08-14 1998-09-15 Abbott Laboratories Detection of hepatitis GB virus genotypes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464474A (en) * 1980-07-09 1984-08-07 Connaught Laboratories Limited Non-A, non-B hepatitis assay and vaccine
US4702909A (en) * 1982-05-05 1987-10-27 Louisiana State University A & M Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent
DE3316464A1 (de) * 1983-05-05 1984-11-08 Heinrich Prof Dr Med Liehr Virusantigen, verfahren zu seiner gewinnung und anwendung in diagnose und therapie (impfstoff)
ZA8410091B (en) * 1984-03-02 1985-08-28 Warner Lambert Co Detection of non-a,non-b hepatitis
US4707439A (en) * 1984-10-26 1987-11-17 The United States Of America As Represented By The Department Of Health And Human Services Screening test for reverse-transcriptase containing virus such as non-A, non-B hepatitis, NANBH
US4673634A (en) * 1985-03-08 1987-06-16 The United States Of America As Represented By The Department Of Health And Human Services Purified antigen from non-A, non-B hepatitis causing factor
JPS62181798A (ja) * 1986-02-06 1987-08-10 Isao Ono モノクロ−ナル抗体
WO1987005930A1 (en) * 1986-04-01 1987-10-08 Genelabs Incorporated Immortalized virus-specific tissue cells
JPS6391328A (ja) * 1986-10-07 1988-04-22 Mitsubishi Kasei Corp 非ａ非ｂ型肝炎抗原
FR2606515B1 (fr) * 1986-11-07 1992-02-21 Pasteur Institut Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie
US5032511A (en) * 1987-03-31 1991-07-16 Mitsubishi Kasei Corporation DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens
JPH06156196A (ja) * 1992-11-25 1994-06-03 Mitsuba Electric Mfg Co Ltd ワイパ装置の間欠時間制御方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No relevant documents have been disclosed. *

Also Published As

Publication number Publication date
CN1041005A (zh) 1990-04-04
EP0423239A1 (en) 1991-04-24
AU4046489A (en) 1990-02-05
WO1990000597A1 (en) 1990-01-25
JPH04501203A (ja) 1992-03-05

Similar Documents

Publication Publication Date Title
EP0423239A4 (en) Post-transfusion, non-a, non-b hepatitis virus and antigens
NZ236491A (en) Post-transfusional non-a non-b hepatitis viral polypeptides, dna, antigenic polypeptides and antibodies to the polypeptides
CA2005950A1 (en) Non-a, non-b hepatitis virus genome rna, cdna and virus antigen protein
EP0463848A3 (en) Non-a, non-b hepatitis virus particles
EP0058676A4 (en) NON-A, NON-B HEPATITIS SAMPLE AND VACCINE.
AU6860891A (en) Non-a, non-b hepatitis virus genomic cdna and antigen polypeptide
GB2108527B (en) Non-a non-b hepatitis virus
ZA912040B (en) Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
EP0419576A4 (en) Enterically transmitted non-a/non-b hepatitis viral agent
EP0532167A3 (en) Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
AU4193789A (en) Detection of non-a, non-b hepatitis
EP0586065A3 (en) Antigenic peptides for grouping hepatitis c virus, kit comprising the same and methods for its grouping using the same
DE3267565D1 (en) Non-a, non-b hepatitis-associated antibody conjugate, the use thereof and detection reagent
EP0093438A3 (en) Non-a, non-b hepatitis antigen
ZA8410091B (en) Detection of non-a,non-b hepatitis
ZA928954B (en) Peptides immunochemically reactive with antibodies directed against hepatitis non-A, non-B virus.
DE3175439D1 (en) Non-a, non-b hepatitis assay and vaccine
EP0516270A3 (en) Non-a, non-b hepatitis virus related antigen, antibody, detection systems, polynucleotides and polypeptides
EP0441644A3 (en) Non-a, non-b hepatitis related nucleic acids, antigens, antibodies and their detection reagents
ZA927243B (en) Non-A, Non-B peptides
EP0532746A4 (en) Assay for non-a non-b hepatitis
NO912459L (no) Non-a non-b hepatittviruspartikler.
EP0628572A3 (en) DNA from a NON-A, NON-B hepatitis virus gene and constituent polypeptides.
NO950527D0 (no) Analogifremgangsmåte ved fremstilling av non-A, non-B hepatittvirus-antigenpeptid
AU540153B2 (en) Detection of non-a, non-b hepatitis associated antigen

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19910102

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19920402

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17Q First examination report despatched

Effective date: 19920827

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930107