FR2606515B1 - Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie - Google Patents

Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie

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Publication number
FR2606515B1
FR2606515B1 FR8615625A FR8615625A FR2606515B1 FR 2606515 B1 FR2606515 B1 FR 2606515B1 FR 8615625 A FR8615625 A FR 8615625A FR 8615625 A FR8615625 A FR 8615625A FR 2606515 B1 FR2606515 B1 FR 2606515B1
Authority
FR
France
Prior art keywords
antigen
viral agent
isolating
detecting
immunological reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8615625A
Other languages
English (en)
Other versions
FR2606515A1 (fr
Inventor
Jacques Pillot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut Pasteur de Lille
Priority to FR8615625A priority Critical patent/FR2606515B1/fr
Priority to NZ222465A priority patent/NZ222465A/xx
Priority to ZA878303A priority patent/ZA878303B/xx
Priority to NZ23540287A priority patent/NZ235402A/xx
Priority to DE8787402519T priority patent/DE3784484T2/de
Priority to EP87402519A priority patent/EP0277437B1/fr
Priority to ES87402519T priority patent/ES2054696T3/es
Priority to AU82734/87A priority patent/AU611402B2/en
Priority to PCT/FR1987/000441 priority patent/WO1988003410A1/fr
Priority to JP62506994A priority patent/JP2602517B2/ja
Priority to AT87402519T priority patent/ATE86120T1/de
Publication of FR2606515A1 publication Critical patent/FR2606515A1/fr
Priority to DK375388A priority patent/DK375388A/da
Application granted granted Critical
Publication of FR2606515B1 publication Critical patent/FR2606515B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24221Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
FR8615625A 1986-11-07 1986-11-07 Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie Expired - Lifetime FR2606515B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8615625A FR2606515B1 (fr) 1986-11-07 1986-11-07 Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie
ZA878303A ZA878303B (en) 1986-11-07 1987-11-05 A process for isolating and characterizing a new viral agent and its associated antigen,the antigen and viral agent obtained by this process,and detection procedures for non a,non b hepatitis using suitable immunological reagents
NZ23540287A NZ235402A (en) 1986-11-07 1987-11-05 Detection of non-a, non-b hepatitis, reagents and kits
NZ222465A NZ222465A (en) 1986-11-07 1987-11-05 Nanb (non a, non b hepatitis viral) antigen
EP87402519A EP0277437B1 (fr) 1986-11-07 1987-11-06 Agent viral de l'hépatite NANB, antigène et réactif immunologique
ES87402519T ES2054696T3 (es) 1986-11-07 1987-11-06 Agente viral de la hepatitis nanb, antigen y reactivo inmunologico.
DE8787402519T DE3784484T2 (de) 1986-11-07 1987-11-06 Hepatitis nanb-viraler stoff, antigen und immunologisches reagenz.
AU82734/87A AU611402B2 (en) 1986-11-07 1987-11-06 Viral agent for nanb hepatitis, antigen and immunologic reagent
PCT/FR1987/000441 WO1988003410A1 (fr) 1986-11-07 1987-11-06 Agent viral de l'hepatite nanb, antigene et reactif immunologique
JP62506994A JP2602517B2 (ja) 1986-11-07 1987-11-06 非a非b型肝炎由来の新規ウイルス因子及びそれに結合した抗原の単離方法、この方法で得られたウイルス因子及び抗原、この抗原の検出方法並びに非a非b型ウイルス性肝炎検出用免疫試薬、その製造法及び用途
AT87402519T ATE86120T1 (de) 1986-11-07 1987-11-06 Hepatitis nanb-viraler stoff, antigen und immunologisches reagenz.
DK375388A DK375388A (da) 1986-11-07 1988-07-06 Nanb hepatitisvirusmiddel, antigen og immunologisk reagens

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8615625A FR2606515B1 (fr) 1986-11-07 1986-11-07 Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie

Publications (2)

Publication Number Publication Date
FR2606515A1 FR2606515A1 (fr) 1988-05-13
FR2606515B1 true FR2606515B1 (fr) 1992-02-21

Family

ID=9340678

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8615625A Expired - Lifetime FR2606515B1 (fr) 1986-11-07 1986-11-07 Procede pour l'isolement d'un nouvel agent viral et de l'antigene qui lui est associe, agent viral et antigene obtenus par ce procede et procede de detection dudit antigene a l'aide d'un reactif immunologique approprie

Country Status (2)

Country Link
FR (1) FR2606515B1 (fr)
ZA (1) ZA878303B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5218099A (en) * 1986-04-01 1993-06-08 The United States Of America As Represented By The Department Of Health And Human Services Post-transfusion, non-A, non-B hepatitis virus polynucleotides
US5789559A (en) 1988-06-17 1998-08-04 Genelabs Technologies, Inc. DNA sequences of enterically transmitted non-A/non-B hepatitis viral agent
US5824649A (en) * 1988-06-17 1998-10-20 Genelabs Technologies, Inc. DNA sequences of enterically transmitted non-A/non-B hepatitis viral agent and characteristic epitopes thereof
AU3748489A (en) * 1988-06-17 1990-01-12 Genelabs Incorporated Enterically transmitted non-a/non-b hepatitis viral agent
JPH04501203A (ja) * 1988-07-06 1992-03-05 ジェネラブズ インコーポレイティド 後―輸血性,非―a,非―b型肝炎ウィルス及び抗原

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356164A (en) * 1979-05-21 1982-10-26 Govt. of the U.S., as represented by the Secretary, Dept. of Health & Human Services Detection of non-A, non-B hepatitis associated antigen
WO1982002774A1 (fr) * 1981-02-11 1982-08-19 Baxter Travenol Lab Virus de l'hepatite non a et non b
US4542016A (en) * 1981-03-27 1985-09-17 Institut Merieux Non-a non-b hepatitis surface antigen useful for the preparation of vaccines and methods of use
FR2502154A1 (fr) * 1981-03-30 1982-09-24 Trepo Christian Procede de preparation d'antigenes de l'hepatite virale nanb, et application a la realisation d'un reactif permettant le diagnostic et le pronostic des infections provoquees par les virus des hepatites virales
JPS57198867A (en) * 1981-06-02 1982-12-06 Eisai Co Ltd Non-a, non-b hepatitis related antigen and diagnostic therefor
JPS58753A (ja) * 1981-06-25 1983-01-05 Eisai Co Ltd 非a非b型肝炎関連抗体および検出試薬
DE3377401D1 (de) * 1982-05-05 1988-08-25 Univ Louisiana State Non-a, non-b hepatitis antigen

Also Published As

Publication number Publication date
ZA878303B (en) 1989-05-30
FR2606515A1 (fr) 1988-05-13

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