EP0419490B1 - Verschlussvorrichtung für ein insbesondere evakuierbares zylinderförmiges gehäuse - Google Patents

Verschlussvorrichtung für ein insbesondere evakuierbares zylinderförmiges gehäuse Download PDF

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Publication number
EP0419490B1
EP0419490B1 EP89903957A EP89903957A EP0419490B1 EP 0419490 B1 EP0419490 B1 EP 0419490B1 EP 89903957 A EP89903957 A EP 89903957A EP 89903957 A EP89903957 A EP 89903957A EP 0419490 B1 EP0419490 B1 EP 0419490B1
Authority
EP
European Patent Office
Prior art keywords
cap
cylindrical housing
seal according
sealing device
sealing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP89903957A
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German (de)
English (en)
French (fr)
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EP0419490A1 (de
Inventor
Franz Konrad
Günther Pakanecz
Manfred Lederer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
greiner Bio-One GmbH
Original Assignee
Greiner & Soehne C A
CA Greiner and Soehne GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Priority claimed from AT97288A external-priority patent/AT403369B/de
Priority claimed from AT314188A external-priority patent/AT391951B/de
Application filed by Greiner & Soehne C A, CA Greiner and Soehne GmbH filed Critical Greiner & Soehne C A
Publication of EP0419490A1 publication Critical patent/EP0419490A1/de
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure device as described in the preamble of claims 1 and 2.
  • an open end face of an evacuable, cylindrical housing is closed with a cap comprising this and a sealing device arranged in it.
  • the sealing device can be pierced and has a sealing surface which is assigned to an inner contact surface of the cylindrical housing. Adjacent to this sealing surface in the direction of the longitudinal axis, a coupling device is arranged between the cap and the sealing device.
  • the coupling parts of this coupling device are formed by a locking extension projecting radially outward from the sealing surface and two extensions. These extensions are arranged at a distance from an end wall of the cap arranged on the side of the sealing device opposite the evacuable, cylindrical housing.
  • the end wall of the cap is provided with a piercing opening for the needle to be inserted into the sealing device.
  • Another known closure device according to EP-A-102 851 describes a closure device for a cylindrical housing which has a closed end and an open end face opposite this.
  • the open end face can be closed with a cap that encompasses this.
  • the cap has a bore in an end wall in which a pierceable sealing device is arranged.
  • the sealing device is provided with a flange-like circumferential projection, which projects beyond the circumferential sealing surface in the region of an end face of the cylindrical housing by approximately the wall thickness of the housing. With this flange-like approach, the sealing device is supported on a projection of the cap. It is disadvantageous that when the sealing device is inserted into the cylindrical housing or when a needle used to fill the housing or to withdraw liquids from the housing is pulled out, the sealing device can be pulled out of the cap.
  • a closure device for a cylindrical housing in particular a blood sample tube, is known - according to AT-B-379 069 and EP-A-0 150 172 by the same applicant - which is formed by a cap comprising an open end face of the cylindrical housing.
  • a bore is arranged in the cap and a sealing device is provided between this and an interior of the cylindrical housing.
  • protruding projections are provided over the surface of the cap, which are covered by the sealing device.
  • a disadvantage of these closure devices is that sometimes very high forces have to be applied in the longitudinal direction of the cylindrical housing in order to increase the adhesive forces between the sealing device and the cylindrical housing overcome, so that it can repeatedly come out of the medication or body fluids stored in these cylindrical housings and thus lead to burns or infections, especially when processing blood contaminated with AIDS. It is also disadvantageous with these closure devices that when the sealing device is pierced with a needle to remove the contents, the closure device can be opened unintentionally.
  • the present invention has for its object to provide a closure device for a cylindrical housing, in particular a blood sample tube, with which a secure gas-tight closure of the interior of such a cylindrical housing can be maintained even over a longer storage period and which on the one hand a relative movement between the closure device and to effectively prevent the cylindrical housing in the longitudinal direction and to enable careful opening.
  • a closure device for a cylindrical housing in particular a blood sample tube
  • a secure gas-tight closure of the interior of such a cylindrical housing can be maintained even over a longer storage period and which on the one hand a relative movement between the closure device and to effectively prevent the cylindrical housing in the longitudinal direction and to enable careful opening.
  • an abrupt escape of the content from the cylindrical housing is also to be prevented.
  • This object of the invention is achieved by the features in the characterizing part of claim 1.
  • the surprising advantage of this arrangement is that a clear movement connection between the sealing device and the cap can be achieved in both directions of movement, that is to say both when the sealing device is inserted into the cylindrical housing and when it is pulled out of the same.
  • a fixed coupling between the sealing device and the cap is created, which, when piercing, i.e. when inserting a needle for filling the housing or for removing the contents from the housing or also when removing this needle from the sealing device, an unintentional release the sealing device is excluded from the cap.
  • this design of the coupling device eliminates the risk of damage to the sealing surfaces and a subsequent leakage or reduced vacuum tightness of the sealing device when the sealing device is inserted into the cap.
  • the surprising advantage of this solution is that the sealing device can be inserted into the cap from any side.
  • this also enables simpler, fully automatic manufacture of such closure devices in the course of a fully automated manufacturing or assembly process.
  • Another embodiment of a closure device as described in the preamble of claim 2 is advantageous.
  • This training is characterized by the features in the characterizing part of claim 2.
  • Another embodiment variant describes claim 3.
  • the fact that the sealing device in the area of the ribs is compressed more when inserted into the tubular insert leads to a better spreading of the sealing device in the tubular extension and to a clawing of the ribs in the surface of the sealing device, so that this is properly carried in the direction of the longitudinal axis of the cap.
  • Due to the longitudinal corrugation with the ribs on the inner Surface of the tubular extension is also improved entrainment of the sealing device in the circumferential direction, since the projecting ribs act in the manner of a toothing and thus reliably take the sealing device along with this toothing when the cap is rotated in the circumferential direction.
  • An embodiment according to claim 5 is also advantageous, since the position of the sealing device can thus be exactly maintained not only when the cap is pulled out, but also when the cylindrical housing is pushed in and closed.
  • Another embodiment variant is characterized in claim 6, whereby the ribs claw particularly well in the cylindrical housing, particularly when the sealing device is pulled out, and thus reliable removal from the cylindrical housing is achieved.
  • An embodiment according to claim 7 is also advantageous, since such sealing devices already have many years of experience with regard to medication and body fluid tolerance, and corresponding experience with dimensioning, on the one hand to achieve gas tightness and on the other hand to permit piercing with hollow needles.
  • the sealing device of the closure device can withstand an axial load such as occurs when piercing with a larger diameter needle.
  • the liquid stored in the tube can be removed from the tube, e.g. can be suctioned off without the closure device having to be opened.
  • Another embodiment variant is provided according to claim 10.
  • the assembly of the sealing device in the cap is facilitated by the spacing of the coupling parts on the circumference.
  • This version is particularly advantageous where automated assembly methods for closing the cylindrical housing are used.
  • An embodiment according to claim 12 is also advantageous. This surprisingly easily achieves a rotation-proof connection of the sealing device in the cap.
  • Another embodiment variant is characterized in claim 13. This makes it easier to join the sealing device and the cap 5.
  • An embodiment according to claim 16 is also advantageous. Through the opening in the attachment part, it is also possible to use the sealing device with, for example to pierce a needle for taking the drug or the body fluid from the cylindrical housing.
  • the C-shaped spring ring is a surprisingly simple component for the effective mounting of the sealing device against undesired axial displacements relative to the cap. It also enables the use of a hard casing arranged on the circumference of the sealing device. In this embodiment, the replacement of the sealing device is also surprisingly easy.
  • An embodiment according to claim 18 is also advantageous.
  • the advantage of designing the sealing arrangement from a composite material is that a core area of the cylindrical sealing device can be designed to be highly elastic, as a result of which reliable sealing is ensured even after the sealing device has been pierced with a needle.
  • the hard sheathing of the sealing device ensures that the sealing device is properly fixed and held between the locking projections arranged in the cap or molded onto the cap.
  • a further development according to claim 19 is also advantageous.
  • the high elasticity is achieved in the core area, which enables the sealing device to be closed elastically after the piercing.
  • the harder design of the coupling parts ensures that the sealing device is fixed in a surprisingly simple manner against the effects of forces in the axial and radial directions.
  • Another embodiment variant is characterized in claim 20. It is thereby advantageously achieved that the guide extensions disengage from the grooves formed between the webs and can be rotated as desired in the circumferential direction without the closure device being opened. Only by moving the cap in the longitudinal direction of the axis of the cylindrical housing away from it, do the webs or the grooves located between them come into engagement with the guide extensions and then the locking device can be turned further be opened. As a result, a safety lock is achieved in a simple manner, by means of which unintentional opening of the cylindrical housing is reliably avoided.
  • Another embodiment describes claim 21. This makes it possible, even if the guide extensions are not arranged directly in the region of the front end of the cylindrical housing, to achieve that in the closed state the guide extensions can be freely rotated in the circumferential direction without it an unintentional opening of the closure device comes.
  • Another embodiment is characterized in claim 23, whereby the course of the webs and the opening movement can be easily adapted to the type of sealing surfaces or sealing devices used, for example O-rings, plugs or caps or the like.
  • cap itself can be used both for sealing and for mechanical fixation on the cylindrical housing and the sealing device or the sealing element with the sealing surface running perpendicular to the longitudinal axis of the cylindrical housing on the additionally necessary medical Requirements such as sufficient gas tightness can also be eliminated after piercing a hollow needle or the like.
  • a further development according to claim 26 is also possible, as a result of which a movement-resistant connection between the sealing device and the cap is created both in the longitudinal direction of the longitudinal axis of the cylindrical housing and in the circumferential direction.
  • This makes it possible to detach the cap from the cylindrical housing by means of a combined longitudinal and rotary movement in the manner of a helix.
  • the relatively high adhesion existing after a longer transport can be fastened by the rotationally fixed connection between the cap or the sealing device in the cylindrical housing by rotating the sealing device relative to the cylindrical housing and thereby removing the cap with less effort in the direction of the longitudinal axis of the cylindrical housing are made possible.
  • Another embodiment variant is provided according to claim 28.
  • This makes it possible to find what is needed with a single sealing device, which has both the circumferential and the sealing surface running perpendicular to the longitudinal axis.
  • the tubular extension also makes it possible to generate a desired prestress or surface pressure between the circumferential sealing surface and the inner surface of the cylindrical housing if an outer diameter of the sealing device is larger than an inner diameter of the cylindrical housing. Due to the strength of the tubular extension or its elasticity, the contact pressure can be fixed in the radial direction between the sealing device and the inner surface of the cylindrical housing and can be maintained over a longer period even if the material of the sealing device shrinks due to the higher elasticity.
  • a further development according to claim 29 is also advantageous since the adhesive forces which can cause the sealing surface to adhere firmly to the inner surface of the cylindrical housing are smaller due to the smaller contact surface. Nevertheless, a very good seal can also be achieved against gas leakage.
  • An embodiment variant according to claim 32 is also possible, as a result of which a sufficient contact of the tubular attachment on the inner surface of the cylindrical housing and thus an adequate seal against both the escape of liquid and the exit or entry of gases is achieved.
  • An embodiment variant according to claim 33 is also advantageous, as a result of which the contact pressure of the sealing surfaces on the inner surface of the cylindrical housing can be easily determined by means of the predetermined difference. This system pressure can also ensure the desired gas and liquid tightness at the same time.
  • an embodiment according to claim 34 is also possible. Due to the elastic adjustability of the locking projections designed in the manner of pawls, it is surprisingly simple to also seal devices, e.g. consist of composite materials with a highly elastic core and a resistant ring-shaped sheathing.
  • a further development according to claim 35 is also advantageous, as a result of which no additional parts are required for holding the sealing device in the cap.
  • the cap can thus be produced in a single operation, for example by injection molding in a multiple arrangement in injection molds can be produced inexpensively.
  • Another embodiment variant is characterized in claim 36.
  • the elasticity of the finger-like extensions can be easily adapted to application-specific requirements by selecting the spring force of the metal springs.
  • the closure device 1 shows a closure device 1 for closing an open end face 2 of a cylindrical housing 3.
  • This cylindrical housing 3 can be used, for example, as a blood sample tube 4.
  • the closure device 1 consists of a cap 5 comprising this open end face 2 and a sealing device 6.
  • the cap 5 is provided with a bore 8 running concentrically to a longitudinal axis 7.
  • a tubular extension 9 adjoins this, which extends from an end wall 10 in the direction of an open end 11 of the cap 5 and thus parallel to a cap jacket 12.
  • a coupling device 13 between the cap 5 and the sealing device 6 consists of the tubular extension 9, a groove 14 arranged in the sealing device and locking projections 16 arranged on an inner surface 15 of the tubular extension 9.
  • the sealing device 6 is a sealing cap 17 formed and has a circumferential sealing surface 18 and a vertical to the longitudinal axis 7 of the cap 5 and to a longitudinal axis 19 of the cylindrical housing 3 extending sealing surface 20.
  • the circumferential sealing surface 18 is assigned to a contact surface 21 in the interior of the cylindrical housing 3.
  • This cylindrical housing 3 is further provided with guide projections 22, 23 which project over the surface 24 of the cylindrical housing 3 on the circumference and are arranged in the region of the open end face 2 thereof.
  • These guide extensions 22, 23 are arranged together with webs 25, 26 on an inner side 27 of the cap jacket 12 and run in a spiral shape. They form a coupling device 28 between the cap 5 and the cylindrical housing 3.
  • FIG. 2 it is shown that the guide extensions 22, 23 are arranged approximately at an angle 29 in the size of approximately 180 ° distributed over the circumference of the cylindrical housing 3.
  • the webs 25 and 26 extend over an opening angle 30 which is less than 180 °.
  • the sealing device 6 is inserted into the cap 5.
  • the sealing cap 17 is pushed onto the extension 9 so that it penetrates into the groove 14.
  • the sealing cap 17 is deformed when pushed over the locking projections 16 designed as ribs 31.
  • these ribs 31 are provided on their end facing the end wall 10 with end faces 32 running approximately perpendicular to the longitudinal axis 7.
  • the sealing cap 17 slides, which can be formed, for example, from a rubber, in particular bromobutyl rubber, silicone rubber, thermoplastic rubber or the like.
  • a rubber in particular bromobutyl rubber, silicone rubber, thermoplastic rubber or the like.
  • the sealing cap 17 can be pulled out of the cap, even if it is held in the cylindrical housing 3 by high adhesive forces between the sealing surface 18 and the contact surface 21, without becoming detached from the cap 5 to solve.
  • the sealing cap 17 is furthermore deformed in the manner of a gearwheel by the ribs 31 distributed over the circumference of the inner surface 15.
  • the closure device 1 also has a further coupling device 28, which, however, does not necessarily have to be arranged in connection with the illustrated embodiment of the cap 5.
  • the function of this coupling device 28 is such that when the cap 5 is pushed in the direction of the longitudinal axis 7 and 19 onto the open end face of the cylindrical housing 3, the webs 25, 26 run onto the guide extensions 22, 23 with a corresponding clockwise rotation. The cap is then pushed onto the cylindrical housing 3 by the combined rotary and longitudinal movement due to the guide of the webs 25, 26 along the guide extensions 22 and 23. This adjustment movement is continued until the guide extensions 22, 23 are from a lower transverse plane 33, in each of which there is a start 34 of the webs 25, 26, into the region of an upper transverse plane 35, in which ends 36 of the webs 25 and 26 are adjusted.
  • the cylindrical housing 3 can be made from glass or from a corresponding plastic, for example polyethylene terephthalate or its copolymers.
  • a gas barrier layer 41 to the outer surface 24, which can be formed, for example, from a polyvinylidene chloride.
  • This gas barrier layer is to be applied towards the open end face on the cylindrical housing 3 to such an extent that the contact surface 21 or sealing surface 18 and this gas barrier layer 41 overlap.
  • the sealing cap 17 is integrally formed and includes the circumferential sealing surface 18 and the vertical sealing surface 20, this sealing cap 17 also forms the gas barrier for an interior 42 of the cylindrical housing 3rd
  • a distance 43 between the end wall 10 and the transverse plane 35 closer to it is larger than a length 44 of the guide extensions 22, 23 parallel to it Longitudinal axis 19 of the cylindrical housing 3.
  • a thickness 45 of the circular ring of the sealing cap 17 located between the groove 14 and the sealing surface 18 is greater than half the difference between an outer diameter 46 of the extension 9 and an inner diameter 47 of the cylindrical housing 3. Having an outer diameter the groove 14 substantially corresponds to the outer diameter 46 of the extension 9, the sealing cap 17 cannot deflect inwards when the sealing cap 17 is pressed into the cylindrical housing 3. The excess of the sealing cap 17 due to the greater thickness 45 must therefore be absorbed by an elastic deformation of the sealing cap 17, as a result of which a correspondingly high surface pressure is built up between the sealing surface 18 and the contact surface 21, which also provides a gas-tight closure of the interior over a longer period of time 42 enables.
  • FIG. 3 shows an embodiment variant of the coupling device 13 in which 3 coupling openings 48 are arranged in a cap 5 for closing a cylindrical housing.
  • Coupling arms 49 which protrude above the sealing device 6, engage in these coupling openings 48.
  • the coupling openings 48 are distributed over the circumference of the cap 5 at the same angular distance as the coupling arms 49 on the sealing device 6.
  • a distance 50 between the sealing surface 18 when the sealing device 6 is relaxed and the inside 27 of the cap 5 is smaller than a wall thickness 51 of the cylindrical housing 3.
  • the sealing surface 18 of the sealing device 6 can be provided with longitudinal slots 52. These have the effect that, before the sealing device 6 emerges from the cylindrical housing, air can already enter the interior 42 through the longitudinal slots 52 and pressure equalization takes place. If the sealing device 6 is then completely pulled out of the cylindrical housing, the medication or the body fluid does not spill over.
  • the sealing device 6 is firmly connected to the cap 5 both in the direction parallel to the longitudinal axis 7 of the cap 5 and in the circumferential direction.
  • the cap 5 is provided with a tubular extension 9, as already shown, for example, with the aid of the representations in FIGS. 1 and 2.
  • the sealing device 6 is pushed over the tubular extension 9 and is designed approximately in the manner of a sealing cap 17.
  • the coupling device 13 between the cap 5 and the sealing device 6 further comprises locking projections 16 which are designed in the manner of barbs 53. Namely, they consist essentially of tips directed against the end wall 10 of the cap 5, which drill holes when the sealing device 6 is pushed in the direction of the end wall 10 onto the tubular extension 9 into the interior of the sealing device 6, and thus the position of the sealing device 6 opposite the cap 5 clearly set.
  • FIG. 5 shows another embodiment variant of the coupling device 13 between the cap 5 and the sealing device 6.
  • locking projections 16 are arranged on an end of a tubular extension 9 projecting in the direction of the open end 11 of the cap 5, into which a coupling disk 54, the anchoring 55 of which is injected or cast into the sealing device 6, engages.
  • sealing device 6 shows an embodiment variant in which the sealing device 6 is formed by two different sealing elements 56 and 57.
  • the sealing elements 57 form the circumferential sealing surface 18, while the sealing element 56 forms the sealing surface running perpendicular to the longitudinal axis 7.
  • grooves 58 which support the sealing elements 57 designed as O-rings, can be provided with transverse ribs 59 or a corrugation, so that when they are clamped between the cylindrical housing 3 and the tubular extension 9 of the cap 5 , rotate with it when the cap 5 is turned.
  • cap 5 is provided with webs 25, 26 in order to enable careful opening and closing of a cylindrical housing 3 via this coupling device 28.
  • FIG. 7 shows an embodiment of a coupling device 28 between a cap 5 and a cylindrical housing 3 in a diagrammatic representation. It can be seen from this illustration that the beginning 34 of the webs 25, 26 is arranged on a transverse plane 33, while the ends 36 are located on a transverse plane 35. The beginning of the web 25 or 26 and the end 36 are each offset by approximately 180 ° in the circumferential direction of the cap 5. Guide projections 22 and 23 are assigned to the two webs 25 and 26, which project over an outer surface 24 of the cylindrical housing 3, for example a blood test tube 4.
  • the guide extensions 22 and 23 with the guide extensions come after the cap has been pushed onto the cylindrical housing 3 up to the transverse plane 33 Bars 25 and 26 are engaged. If the cap 5 is rotated in the clockwise direction - arrow 61 - its end wall 10 moves it ever closer to the guide extensions 22, 23 until the end 36 of the webs 25, 26 has passed in the area of the transverse plane 35. In this position, the cap 5 can now be rotated as desired. As long as it is not removed from the cylindrical housing 3 and the guide extensions 22 and 23 come to rest on the underside 39 of the webs 25, 26, the cap 5 cannot be removed.
  • the cap 5 also has a bore 8 through which access to the interior 42 of the cylindrical housing 3 is possible by means of an injection needle or the like.
  • the hole can be omitted in the event that removal of the liquid should only be possible after opening the cap 5.
  • the cap 5 can be coupled to a sealing device 6 via this bore 8 or in any other manner according to the exemplary embodiments described above, with which a sealing of the cylindrical housing is also possible.
  • FIGS. 8 and 9 show an embodiment variant of a closure device 1 in which the coupling device 28 has three webs 25, 26 and 62.
  • the webs 25, 26 and 62 each extend over an angular range of approximately 270 °.
  • Each of the webs 25, 26, 62 is assigned a guide extension 22, 23 and 63, which is connected in one piece to the cylindrical housing 3, for example a blood test tube, or molded onto it or produced by a special shaping, for example a subsequent hot deformation.
  • the individual guide extensions 22, 23 and 63 are offset in the circumferential direction by an angle 64 of approximately 120 °. The same applies approximately to the beginning 34 of the webs 25, 26 and 62.
  • the sealing device 6, which forms both the circumferential sealing surface 18 and the sealing surface 20 running perpendicular to the longitudinal axis 7, is positively connected to the cap jacket 12 .
  • This form-fitting connection is achieved in that another plastic with highly elastic properties for producing the sealing device 6 is injected into the mold during the injection molding process for producing the cap jacket 12 with the end wall 10. This results in a fusion process between the two types of material in the area of a seam 65 indicated by a serrated line.
  • the sealing device 6, after the cap 5 has been produced is injection molded into the bore 8 of the cap 5 is injected or foamed.
  • this sealing device 6 is formed from a plastic foam, for example a polyvinylidene chloride foam or a polyurethane foam or the like. It is only essential that the plastic used is a has sufficient gas tightness and elasticity to enable a gas-tight closure of the cylindrical housing 3 or the blood sample tube 4.
  • FIG. 10 shows an embodiment in which a cap 5 is in turn provided with a sealing device 6 molded onto it.
  • the cap 5 webs 25, 26 are arranged, the beginning 34 of which are arranged on a transverse plane 33 and the ends 36 of which are arranged on a transverse plane 35.
  • a pitch angle 66.67 of the webs 25.26 is different over their course.
  • the pitch angle 66 runs relatively flat in the start and end area of the webs 25, 26, i.e. approximately perpendicular to the longitudinal axis 7 of the cap 5, while it runs very steeply between these regions, that is to say almost parallel to the longitudinal axis 7.
  • FIG. 11 shows a further embodiment of the invention, in which three webs 25, 26 and 62 are arranged in a cap 5.
  • the arrangement of the webs and their circumferential length, over which these webs extend, can take place, as shown, for example, with reference to the illustration in FIGS. 8 and 9.
  • the webs 25, 26, 62 arranged in the cap 5 are assigned guide extensions, of which only the guide extension 22 can be seen on the cylindrical housing 3.
  • This guide extension 22 is arranged parallel to a longitudinal axis 19 of the cylindrical housing 3 by a distance 68 from an end face 2 of the cylindrical housing 3.
  • This distance 68 corresponds to a distance 69 between the end wall 10 of the cap 5 and the transverse plane 35 or is slightly smaller.
  • the circumferential sealing surface 18 can be brought into engagement with the contact surface 21 in the cylindrical housing 3.
  • two different sealing elements 70, 71 are arranged for producing the sealing surface 20 running perpendicular to the longitudinal axis and for producing the circumferential sealing surface 18.
  • the sealing element 71 is designed in the manner of a stubble, which is secured by a corresponding design of the bore 8 in the end wall 10 against falling out in both directions when subjected to a force from the outside.
  • the sealing element 71 is, for example, foamed or sprayed onto a tubular extension 9 which connects to the bore 8. This foaming or spraying can take place simultaneously with the manufacture of the cap 5 or separately therefrom. With such a separation of the sealing surface 18 from the sealing surface 20 and the use of two different sealing elements, care must be taken that the tubular extension 9 is also appropriately gas-tight or is provided with a gas barrier layer 41, so that gas entry or exit through the Plastic of this part is sufficiently prevented.
  • the coupling device for connecting the cap 5 to the sealing device 6 has both the circumferential sealing surface 18 and the sealing surface 20 running perpendicular to the longitudinal axis 19, from the front wall 10 of the cap 5 in the direction of the open end 11 projecting coupling arms 72 which engage in coupling openings 73 of the sealing device 6 is formed.
  • the sealing device 6 is connected to the cap 5 so as to be fixed in terms of motion both in the direction of the longitudinal axis 19 and in the circumferential direction.
  • An interior 42 is accessible through the bore 8 in the cap 5.
  • a further coupling device 28 with webs 25, 26 for locking the cap 5 on a cylindrical housing 3, for example a housing of an injection syringe or on a blood test tube 4, can be provided.
  • the two coupling devices 13 and 28 can also be used completely independently of one another only for such caps 5 or closures for containers for receiving medication, food, body fluids, cleaning agents or the like.
  • the use of such coupling devices is advantageous wherever a gas-tight seal is to be achieved and there is a risk that, due to the gas-tight seal, the contents will spurt out, especially when opened, and this can lead to infections, infections or burns.
  • the sealing device 6 or the sealing elements 56, 57 or 70, 71 are connected to the cap 5 via an adhesive layer.
  • the coupling arms 72 can be glued in the coupling openings 73 or the coupling arms 49 in the coupling openings 48.
  • FIG. 13 also shows an embodiment in which the webs 25 or 26 and 62 are arranged on the cylindrical housing 3.
  • the webs can be molded directly into the cylindrical housing 3 during the manufacturing process or can be produced by subsequent thermal deformation.
  • the guide extensions 22, 23 and 63 assigned to these webs 25, 26 and 62 protrude inward beyond the cap jacket 12.
  • An inner diameter 74 of the cap jacket 12 is larger than a maximum outer diameter 75 of the cylindrical housing 3 in the region of the webs 25, 26 and 62.
  • a length 76 of the guide projections 22, 23 and 63 projecting inward beyond the cap jacket 12 is less than half of a difference between the inner diameter 74 and the outer diameter 75. This ensures that the guide extensions 22, 23, 63 and the webs 25, 26, 62 overlap one another, so that the guide extensions 22, 23, 63 are guided along the webs 25, 26 and 62 is possible.
  • the function of opening and closing the cylindrical housing 3 with the closure device 1 in the illustrated embodiment is as follows:
  • the cap 5 with the guide extensions 22, 23, 63 is moved towards the cylindrical housing 3 by a movement in the direction of the arrow 60, that is to say in the direction of the longitudinal axis 19, and is turned in the direction of the arrow 77 with a slight application of force in the direction of the cylindrical housing 3 .
  • the guide extensions 22, 23, 63 come to rest on the underside 39 of the webs 25, 26, 62.
  • the cap 5 is pulled onto the cylindrical housing in the direction of arrow 60. If the ends 36 of the webs 25, 26, 62 are now reached, the cap 5 can be rotated endlessly and ratchets with its guide extensions 22, 23, 63 over the ends 36 of the webs 25, 26, 62.
  • the cap 5 is to be rotated in the direction opposite the arrow 77 and in the process is to be moved relative to the cylindrical housing 3 in the direction opposite the arrow 60 or to be lifted off from it.
  • the guide extensions 22, 23, 63 run onto the upper side 38 of the webs 25, 26, 62 and the cap becomes in the direction of further rotation the arrow 77 pulled out of the cylindrical housing 3.
  • a groove width 78 between the webs 25, 26, 62 running perpendicular to the longitudinal axis 7 of the cap 5 or 19 of the cylindrical housing 3 is greater than a width 79 of the guide extensions 22, 23, 63, as this can be seen better with reference to FIGS. 8 and 9. If the width 79 is chosen too large, jamming between the guide extensions and the webs can occur when opening and closing. These deadlocks can be reduced if the edges of the extensions are rounded or these extensions are formed, for example, in the form of a spherical cap.
  • the sealing device 6 is designed approximately in the manner of a cup and, as the coupling part 81, has a flange-shaped locking extension 16 with a diameter 82 which is approximately twice the wall thickness 51 of the cylindrical housing 3 larger than a diameter 83 of a cylindrical one adjoining the locking extension Sealing surface 18.
  • the tubular cap 5 receiving the sealing device 6 has an inner diameter which essentially corresponds to the diameter 82 of the flange-shaped locking extension 16 and thus roughly corresponds to a diameter 84 of the cylindrical housing 3.
  • coupling parts 81 for example annular extensions 86, 87, which extend over the cylindrical inner surface of the cap 5 in the direction of the longitudinal axis 19 protrude and delimit a groove-shaped receiving area 88 for the locking extension 16.
  • An inner diameter of an opening 89 of the extensions 86, 87 corresponds approximately to the diameter 83 of the cylindrical housing 3.
  • the diameter 84 of the cylindrical housing 3 protrudes uniformly on the circumference in a vertical plane to the longitudinal axis 19, for example guide extensions 22 arranged at an angular distance of 120 °.
  • these guide extensions 22 are assigned spiral guide tracks 90 on the cylindrical inner surface of the cap 5, which together form the coupling device 28 form for the closure device 1 with the cylindrical housing 3.
  • the closure device 1 can be released from the cylindrical housing 3 without jerky movement by making a counter-rotating movement of the cap 5 and the sealing device 6, according to arrows 91, 92.
  • the contents of the cylindrical housing 3 can also be sucked out of the cylindrical housing by means of a cannula 93 shown in dashed lines after the sealing device 6 has been pierced.
  • the axial forces that occur when the cannula 93 is pierced and pulled out of the sealing device 6 are absorbed by the flange-like locking extension 16 of the sealing device 6 and the extensions 86, 87 of the cap 5.
  • the closure device 1 is therefore particularly suitable for automated blood analysis apparatuses, such as are often used in laboratories and hospitals.
  • the interlocking coupling parts 80, 81 namely the locking extension 16 and the groove-shaped receiving area 88, achieve a firm holding between the cap 5 and the sealing device 6 in the direction of the longitudinal axis 19.
  • recesses can be provided on the circumference of the locking extension 16 in the direction of the longitudinal axis 19, to which rib-like connecting webs between the extensions 86, 87 are assigned, which form a toothed connection with the recesses in the locking extension 16.
  • a rotational movement connection is also achieved between the sealing device 6 and the cap 5, which means that when the cylindrical housing 3 is opened by unscrewing the closure device 1, the sealing device 6 also carries out the rotating movement of the cap 5 and thus any gluing of the sealing surfaces 18 on the inner wall of the cylindrical housing 3 is released gently for the sealing device 6.
  • FIGS. Hiebei are the flange-shaped locking extension 16 of the sealing device 6 coupling parts 94, formed by extensions 95, 96, assigned to the cap 5, which form the receiving area 88 for the flange-like locking extension 16 of the sealing device 6.
  • the extensions 95, 96 are arranged in the form of a circular segment on the inner circumference of the cap 5 and protrude in the direction of the longitudinal axis 19 and form a circular opening 89 with a diameter which corresponds approximately to the inner diameter 83 of the cylindrical housing 3.
  • the coupling parts are preferably composed of four extensions 95 arranged at an angular distance of 90 °, the total inner circumferential length of which is smaller than the eighth part of the circumference of the circle circumscribed by the extensions 95, which corresponds to the inner diameter 83 of the cylindrical housing 3.
  • the radial axes of symmetry 97, 98 of the coupling parts 94 are arranged at an angular distance 99, which corresponds to approximately 45 °.
  • the space formed by the arrangement of the coupling parts 94 described facilitates the assembly of the sealing device 6, but the flange-like locking extension 16 of the sealing device 6 is held against axial displacement as a result of an axial force acting between the cannula 93 and the sealing device 6 due to the adhesive force.
  • FIG. 17 and 18 also show an embodiment variant in which the coupling part 81 of the sealing device 6 in the form of a flange-like locking extension 16 of the sealing device 6 in the cap 5 is provided by finger-like fingers 80 serving as coupling parts 80 and evenly distributed on the circumference and arranged parallel to the longitudinal axis 19 of the cap 5 Extensions 100 is supported.
  • the tubular cap 5 has an annular projection 101, which protrudes from the cylindrical inner circumference of the cap in the direction of the longitudinal axis 19, an inner diameter of the opening 89 delimited by the projection 101 roughly corresponding to the inner diameter 83 of the cylindrical housing 3 and with the cap 5 integrally connected finger-like extensions 100.
  • contact surfaces 103 arranged on the extension 101 at a distance 102, which corresponds approximately to the width of the flange-shaped locking extension 16 of the sealing device 6.
  • the flange-like locking extension 16 of the sealing device 6 is held between the shoulder 101 and the contact surface 103.
  • An opening 104 enclosed by the finger-like extensions 100 and arranged concentrically to the longitudinal axis 19 is widened in the shape of a truncated cone in the direction of an end face 105 of the cap 5 opposite the cylindrical housing 3, with a diameter 106 corresponds approximately to the outer diameter of the flange-shaped locking extension 16.
  • a radial elasticity of the extensions 100 is achieved. This considerably simplifies the insertion of the sealing device 6 into the receiving area 88 of the cap 5, which also makes it possible without further ado to form the sealing device 6 from multi-component material, for example with a highly elastic core and a resistant, harder casing, for example in the area of the flange-like locking extension 16 to press this sealing device 6, which is very resistant to axial displacement, into the receiving area 88.
  • the radial elasticity of the finger-like extensions 100 can be achieved or changed by weakening the material in the area of the shoulder 101 and by an annular spring element inserted in a groove on the outer circumference.
  • FIG. 19 shows a further embodiment variant of a closure device 1 with a sealing device 6.
  • the sealing device 6 has a coupling part 81, e.g. a flange-shaped locking extension 16, to which a projection 101 projecting from the inner surface of the cap 5 in the direction of the longitudinal axis 19 is assigned as a coupling part 80.
  • an annular front end 107 is formed in a bead shape in the direction of the longitudinal axis 19 following the insertion of the sealing device 6. This transformation can e.g. done thermally with a cap 5 made of thermoplastic material.
  • This reshaping forms the receiving area 88 for the flange-like locking extension 16 of the sealing device 6, which secures the immovable positioning in the axial direction.
  • the axial securing of the sealing device 6 can be carried out by a resilient ring 109 inserted in a groove 108 arranged in the cylindrical inner surface of the cap 5.
  • a tubular cap 5 has a cylindrical receiving area 110, which is delimited at a distance 111 from the front end 107 by the attachment 101.
  • this receiving area 110 is the flange Arresting extension 16 of the sealing device 6 is arranged.
  • the front end 107 of the cap 5 encompasses an approximately bow-shaped attachment part 112 which engages like a catch in receptacles 113 arranged diametrically opposite on the outer circumference of the cap 5.
  • the attachment part 112 has an opening 104 concentric to the longitudinal axis 19, the diameter of which is smaller than the diameter of the flange-shaped locking extension 16 of the sealing device 6 and corresponds approximately to the inner diameter 83 of the cylindrical housing 3.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Insulating Bodies (AREA)
  • Pipe Accessories (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pressure Vessels And Lids Thereof (AREA)
  • Catching Or Destruction (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Package Closures (AREA)
  • Making Paper Articles (AREA)
EP89903957A 1988-04-15 1989-04-04 Verschlussvorrichtung für ein insbesondere evakuierbares zylinderförmiges gehäuse Expired - Lifetime EP0419490B1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT97288A AT403369B (de) 1988-04-15 1988-04-15 Verschlussvorrichtung für ein insbesondere evakuierbares zylinderförmiges gehäuse
AT314188A AT391951B (de) 1988-12-23 1988-12-23 Verschlussvorrichtung fuer ein gehaeuse
AT3141/88 1988-12-23
AT972/88 1988-12-23

Publications (2)

Publication Number Publication Date
EP0419490A1 EP0419490A1 (de) 1991-04-03
EP0419490B1 true EP0419490B1 (de) 1993-11-10

Family

ID=25594475

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89903957A Expired - Lifetime EP0419490B1 (de) 1988-04-15 1989-04-04 Verschlussvorrichtung für ein insbesondere evakuierbares zylinderförmiges gehäuse

Country Status (9)

Country Link
EP (1) EP0419490B1 (pt)
JP (1) JP2823914B2 (pt)
AT (1) ATE97085T1 (pt)
AU (2) AU3412589A (pt)
CA (1) CA1322185C (pt)
DE (2) DE8915637U1 (pt)
HK (1) HK30497A (pt)
RU (1) RU2062737C1 (pt)
WO (1) WO1989009735A1 (pt)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5361921A (en) * 1993-06-29 1994-11-08 Becton Dickinson And Company Combination stopper-shield closure
EP2277625A1 (de) 2004-01-23 2011-01-26 Greiner Bio-One GmbH Aufnahmeeinrichtung für Blut, Körperflüssigkeiten, Gewebeteile bzw. Gewebekulturen
WO2015154115A2 (de) 2014-04-09 2015-10-15 Greiner Bio-One Gmbh Aufnahmebehälter sowie aufnahmeeinheit zur aufnahme von körperflüssigkeit
US10618049B2 (en) 2015-05-04 2020-04-14 Greiner Bio-One Gmbh Sampling assembly, in particular for collecting a relatively small quantity
US11305286B2 (en) 2017-05-02 2022-04-19 Greiner Bio-One Gmbh Collection assembly or test tube for a small amount of a body fluid, comprising an extender element

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT401341B (de) * 1990-03-09 1996-08-26 Greiner & Soehne C A Verschlussvorrichtung für ein, insbesondere evakuierbares gehäuse
AT407007B (de) 1998-12-23 2000-11-27 Greiner Labortechnik Gmbh Aufnahmeeinrichtung für ein einsatzelement
DE19962664C2 (de) 1999-12-23 2003-01-30 Helvoet Pharma Verschlußvorrichtung für einen Unterdruck-Probensammelbehälter
AT500247B1 (de) 2001-03-30 2007-06-15 Greiner Bio One Gmbh Aufnahmeeinrichtung, insbesondere für körperflüssigkeiten, mit einer trennvorrichtung sowie trennvorrichtung hierzu
DE20106406U1 (de) * 2001-04-12 2002-08-22 Sulzer Chemtech Ag Winterthur Verschluß für eine Zweikomponenten-Kartusche
DE10223560B4 (de) * 2002-05-27 2006-01-19 Fresenius Kabi Deutschland Gmbh Konnektor für medizinische Flüssigkeiten enthaltende Verpackungen und Verpackung für medizinische Flüssigkeiten
ITVI20020131A1 (it) * 2002-06-17 2003-12-17 Vacutest Kima Srl Tappo con protezione per provette
AT500525A1 (de) * 2003-04-17 2006-01-15 Greiner Bio One Gmbh Aufnahmevorrichtung sowie aus einer dichtungsvorrichtung und kappe gebildete verschlussvorrichtung
EP2111795A4 (en) * 2006-12-27 2017-12-27 Kaneka Corporation Vacuum blood collection tube
ITMI20121793A1 (it) * 2012-10-23 2014-04-24 Copan Italia Spa Elemento di chiusura di un contenitore per fluidi biologici
ES2735090T3 (es) 2014-11-18 2019-12-16 Daikyo Seiko Ltd Cápsula de vial
AT525932A1 (de) 2022-02-17 2023-09-15 Greiner Bio One Gmbh Abnahmebaugruppe für organisches Material

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Publication number Priority date Publication date Assignee Title
US3017050A (en) * 1955-01-10 1962-01-16 Sr Courtland H Barr Blood sample collection apparatus
US3088615A (en) * 1960-07-25 1963-05-07 Owens Illinois Glass Co Closure caps
US3709395A (en) * 1971-07-01 1973-01-09 Hospital Service Technology Co Closure for containers
DE7239445U (de) * 1972-10-27 1973-08-02 Merten Utz P Einwegspritze, insbesondere zur Entnahme von Blutproben
CH566905A5 (pt) * 1973-08-28 1975-09-30 Barrel Fresh Service Ag
CH580962A5 (en) * 1974-08-26 1976-10-29 Kyburz Hans Piston type ampoule closure - with air vent channel on the piston and O-ring or end flange seal
GB1505082A (en) * 1974-11-13 1978-03-22 Searle & Co Containers with screw caps
AU529500B2 (en) * 1978-11-02 1983-06-09 Baxter Travenol Laboratories Inc. Closure for pharmaceutical container
US4206852A (en) * 1979-01-26 1980-06-10 Aluminum Company Of America Linerless closure for pressurized container
US4331233A (en) * 1980-05-30 1982-05-25 The Upjohn Company Activation closure for vial
JPS58213145A (ja) * 1982-06-04 1983-12-12 Matsushita Electric Ind Co Ltd 給湯システム
GB8323954D0 (en) * 1982-09-08 1983-10-12 Donnelly T K Blood sampling containers
US4465200A (en) * 1983-06-06 1984-08-14 Becton, Dickinson And Company Low contamination closure for blood collection tubes
AT379069B (de) * 1984-01-11 1985-11-11 Greiner & Soehne C A Blutprobenroehrchen

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5361921A (en) * 1993-06-29 1994-11-08 Becton Dickinson And Company Combination stopper-shield closure
EP2277625A1 (de) 2004-01-23 2011-01-26 Greiner Bio-One GmbH Aufnahmeeinrichtung für Blut, Körperflüssigkeiten, Gewebeteile bzw. Gewebekulturen
WO2015154115A2 (de) 2014-04-09 2015-10-15 Greiner Bio-One Gmbh Aufnahmebehälter sowie aufnahmeeinheit zur aufnahme von körperflüssigkeit
US10618049B2 (en) 2015-05-04 2020-04-14 Greiner Bio-One Gmbh Sampling assembly, in particular for collecting a relatively small quantity
US11305286B2 (en) 2017-05-02 2022-04-19 Greiner Bio-One Gmbh Collection assembly or test tube for a small amount of a body fluid, comprising an extender element

Also Published As

Publication number Publication date
AU3412589A (en) 1989-11-03
RU2062737C1 (ru) 1996-06-27
HK30497A (en) 1997-03-21
JPH03505320A (ja) 1991-11-21
DE58906179D1 (de) 1993-12-16
ATE97085T1 (de) 1993-11-15
EP0419490A1 (de) 1991-04-03
AU3305089A (en) 1989-10-19
AU626849B2 (en) 1992-08-13
JP2823914B2 (ja) 1998-11-11
DE8915637U1 (de) 1990-11-29
WO1989009735A1 (en) 1989-10-19
CA1322185C (en) 1993-09-14

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