EP0355825A3 - Virusbekämpfungssystem - Google Patents

Virusbekämpfungssystem Download PDF

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Publication number
EP0355825A3
EP0355825A3 EP19890115606 EP89115606A EP0355825A3 EP 0355825 A3 EP0355825 A3 EP 0355825A3 EP 19890115606 EP19890115606 EP 19890115606 EP 89115606 A EP89115606 A EP 89115606A EP 0355825 A3 EP0355825 A3 EP 0355825A3
Authority
EP
European Patent Office
Prior art keywords
persons
suffering
pharmaceutical formulations
drug treatment
infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890115606
Other languages
English (en)
French (fr)
Other versions
EP0355825A2 (de
Inventor
Patrick T. Prendergast
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0355825A2 publication Critical patent/EP0355825A2/de
Publication of EP0355825A3 publication Critical patent/EP0355825A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP19890115606 1988-08-25 1989-08-24 Virusbekämpfungssystem Withdrawn EP0355825A3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE882585A IE882585L (en) 1988-08-25 1988-08-25 Viral treatment system
IE258588 1988-08-25

Publications (2)

Publication Number Publication Date
EP0355825A2 EP0355825A2 (de) 1990-02-28
EP0355825A3 true EP0355825A3 (de) 1991-12-27

Family

ID=11035556

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890115606 Withdrawn EP0355825A3 (de) 1988-08-25 1989-08-24 Virusbekämpfungssystem

Country Status (12)

Country Link
US (1) US5681831A (de)
EP (1) EP0355825A3 (de)
JP (1) JP3237836B2 (de)
KR (1) KR900002786A (de)
AU (1) AU636574B2 (de)
CA (1) CA1339854C (de)
DK (1) DK418489A (de)
FI (1) FI893948A (de)
IE (1) IE882585L (de)
IL (1) IL91415A (de)
OA (1) OA09427A (de)
ZA (1) ZA896450B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung
PH30703A (en) * 1990-06-21 1997-09-16 Patrick T Prendergast Administering particular compounds against variousparasites, mycoplasmas, other indications and otheer indications and other infections.
WO1997038695A1 (en) * 1996-04-17 1997-10-23 Prendergast Patrick T Dhea combination therapy
US5789416B1 (en) * 1996-08-27 1999-10-05 Cv Therapeutics Inc N6 mono heterocyclic substituted adenosine derivatives
FR2759091B1 (fr) * 1997-02-06 1999-03-19 Expertises Ind Et Procede biologique d'obtention de nouveaux derives de l'adenosine et les compositions pharmaceutiques qui les contiennent
AU5221998A (en) * 1997-04-17 1998-11-13 Patrick T. Prendergast Combination therapy utilising 17-ketosteroids and interleukin inhibitors, or interleukin-10 potionally with interleukin inhibitors
US6800616B2 (en) 1998-02-26 2004-10-05 Supergen, Inc. Treatment of HIV infections
CA2552596A1 (en) * 2005-08-09 2007-02-09 Solvay Pharmaceuticals B.V. Methods and systems for determining mid-value titers
AU2011230619C1 (en) 2010-03-25 2016-06-23 Oregon Health & Science University CMV glycoproteins and recombinant vectors
LT2691530T (lt) 2011-06-10 2018-08-10 Oregon Health & Science University Cmv glikoproteinai ir rekombinantiniai vektoriai
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
EP2679596B1 (de) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 Env-proteinvariante
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (de) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2079150A (en) * 1980-06-25 1982-01-20 Iizuka Chiyokichi Antiviral substance from Basidiomycetes

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759011A (fr) * 1969-11-17 1971-05-17 Wellcome Found Aminopurines
DE2052596A1 (de) * 1970-10-27 1972-05-04 Boehringer Mannheim Gmbh, 6800 Mannheim Neuartige Verwendung von N(6)-substituierten Adenosin-Derivaten
US3758684A (en) * 1971-09-07 1973-09-11 Burroughs Wellcome Co Treating dna virus infections with amino purine derivatives
US3966916A (en) * 1972-09-09 1976-06-29 Boehringer Mannheim G.M.B.H. N(6)-disubstituted adenoisine compounds and therapeutic compositions
US4016262A (en) * 1973-08-01 1977-04-05 Boehringer Mannheim G.M.B.H. Therapeutic compositions and methods employing N(6)-disubstituted adenosine compounds
US4007186A (en) * 1974-09-20 1977-02-08 Emanuel Carl F Process for preparing uric acid
JPS57171998A (en) * 1981-04-15 1982-10-22 Fujisawa Pharmaceut Co Ltd Adenosine derivative and its salt, preparation thereof and medicinal composition containing the same
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US5093318A (en) * 1983-11-01 1992-03-03 Scripps Clinic And Research Foundation Immunostimulating guanosine derivatives and their pharmaceutical compositions
US4687733A (en) * 1984-01-30 1987-08-18 Ohio State University Early cancer detection method
US4657897A (en) * 1984-06-22 1987-04-14 Warner-Lambert Company N6 -substituted adenosines for treating pain
US4791103A (en) * 1985-02-08 1988-12-13 Warner-Lambert Company 2,N6 -disubstituted adenosines, derivatives and methods of use
US4605644A (en) * 1985-02-07 1986-08-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia employing ribose and adenine
NZ222051A (en) * 1986-10-06 1990-07-26 Univ Virginia Solution containing adenosine or hypoxanthine and optionally ribose for heart protection during surgery
US4843066A (en) * 1986-11-27 1989-06-27 Nippon Zoki Pharmaceutical Co., Ltd. Novel adenosine derivatives and pharmaceutical composition containing them as an active ingredient
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
IL86009A (en) * 1987-04-10 1991-09-16 Us Health Liposome-encapsulated phosphorylated nucleosides for treatment of retroviral diseases
ATE141796T1 (de) * 1988-06-09 1996-09-15 Univ Temple 2',5'-oligoadenylat-derivate zur verwendung als heilmittel
US5292725A (en) * 1988-08-25 1994-03-08 Prendergast Patrick T Administering particular compounds against various parasites, mycoplasmas, other indications and other infections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2079150A (en) * 1980-06-25 1982-01-20 Iizuka Chiyokichi Antiviral substance from Basidiomycetes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
STN INTERNATIONAL, FILE CA, access. no. 90(11): 80810k; O.I. BRATSLAVISKAYA et al.: "Study of the mechanism of inhibition of moloney's mouse sarcoma virus by N6-(.delta.2-isopentenyl adenosine", & ONKORNAVIRUSY I NESPETSIFICH. REZISTENTNOST ORGANIZMA 29-33 *
VIROLOGY, vol. 38, no. 1, 1969, pages 26-31; G.E. MILO, Jr. et al.: "Effect of cytokinins on tobacco mosaic virus production in local-lesion and systemic hosts" *

Also Published As

Publication number Publication date
FI893948A (fi) 1990-02-26
FI893948A0 (fi) 1989-08-23
JP3237836B2 (ja) 2001-12-10
OA09427A (en) 1992-10-15
AU636574B2 (en) 1993-05-06
ZA896450B (en) 1991-04-24
DK418489D0 (da) 1989-08-24
CA1339854C (en) 1998-05-05
DK418489A (da) 1990-02-26
IL91415A (en) 1995-08-31
AU4025689A (en) 1990-03-01
KR900002786A (ko) 1990-03-23
IL91415A0 (en) 1990-04-29
JPH02237996A (ja) 1990-09-20
EP0355825A2 (de) 1990-02-28
IE882585L (en) 1990-02-25
US5681831A (en) 1997-10-28

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Effective date: 19940301