EP0349902A3 - Procédés pour la préparation de morniflumate et de composés analogues - Google Patents
Procédés pour la préparation de morniflumate et de composés analogues Download PDFInfo
- Publication number
- EP0349902A3 EP0349902A3 EP19890111854 EP89111854A EP0349902A3 EP 0349902 A3 EP0349902 A3 EP 0349902A3 EP 19890111854 EP19890111854 EP 19890111854 EP 89111854 A EP89111854 A EP 89111854A EP 0349902 A3 EP0349902 A3 EP 0349902A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- processes
- morniflumate
- preparation
- analogous compounds
- particularly advantageous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title abstract 2
- LDXSPUSKBDTEKA-UHFFFAOYSA-N morniflumate Chemical compound FC(F)(F)C1=CC=CC(NC=2C(=CC=CN=2)C(=O)OCCN2CCOCC2)=C1 LDXSPUSKBDTEKA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003251 morniflumate Drugs 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8821300A IT1226386B (it) | 1988-07-08 | 1988-07-08 | Procedimento di preparazione di morniflumato e analoghi. |
| IT2130088 | 1988-07-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0349902A2 EP0349902A2 (fr) | 1990-01-10 |
| EP0349902A3 true EP0349902A3 (fr) | 1991-04-10 |
Family
ID=11179752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19890111854 Withdrawn EP0349902A3 (fr) | 1988-07-08 | 1989-06-29 | Procédés pour la préparation de morniflumate et de composés analogues |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0349902A3 (fr) |
| KR (1) | KR0146352B1 (fr) |
| DK (1) | DK336289A (fr) |
| FI (1) | FI893293A7 (fr) |
| IT (1) | IT1226386B (fr) |
| MY (1) | MY104452A (fr) |
| PT (1) | PT91079B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5248781A (en) * | 1992-09-21 | 1993-09-28 | The Trustees Of Princeton University | Preparation of substituted anilino-nicotinic acid derivatives |
| US7608640B2 (en) | 1999-03-02 | 2009-10-27 | Jallal Messadek | Glycine betaine and its use |
| WO2002062322A2 (fr) * | 2001-02-05 | 2002-08-15 | Jallal Messadek | Glycine-betaine et utilisation correspondante |
| BE1015608A6 (fr) | 2003-07-15 | 2005-06-07 | Messadek Jallal | Traitement des arterites. |
| WO2006050581A2 (fr) | 2004-11-10 | 2006-05-18 | Jallal Messadek | Betaine en tant qu'agent de lutte contre des maladies transmises par des arthropodes ou des moustiques |
| EP2242489A1 (fr) | 2005-02-15 | 2010-10-27 | Jallal Messadek | Compositions therapeutiques combinees et leurs procedes d utilisation |
| RU2007143510A (ru) | 2005-04-27 | 2009-06-10 | Яллал МЕССАДЕК (BE) | Инсулиновые композиции |
| CN105777624A (zh) * | 2014-12-26 | 2016-07-20 | 辽宁药联制药有限公司 | 一种微粉化吗尼氟酯及其组合物 |
| WO2018138050A1 (fr) | 2017-01-26 | 2018-08-02 | Bayer Aktiengesellschaft | Dérivés hétérocycliques bicycliques condensés utilisés comme pesticides |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2187317A2 (fr) * | 1972-06-07 | 1974-01-18 | Hexachimie | |
| FR2193580A1 (en) * | 1972-07-26 | 1974-02-22 | Synthelabo | Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines |
| FR2258840A1 (en) * | 1974-01-29 | 1975-08-22 | Synthelabo | (4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use |
-
1988
- 1988-07-08 IT IT8821300A patent/IT1226386B/it active
-
1989
- 1989-06-29 EP EP19890111854 patent/EP0349902A3/fr not_active Withdrawn
- 1989-07-06 PT PT91079A patent/PT91079B/pt not_active IP Right Cessation
- 1989-07-06 MY MYPI89000918A patent/MY104452A/en unknown
- 1989-07-06 DK DK336289A patent/DK336289A/da not_active Application Discontinuation
- 1989-07-06 FI FI893293A patent/FI893293A7/fi not_active Application Discontinuation
- 1989-07-06 KR KR1019890009606A patent/KR0146352B1/ko not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2187317A2 (fr) * | 1972-06-07 | 1974-01-18 | Hexachimie | |
| FR2193580A1 (en) * | 1972-07-26 | 1974-02-22 | Synthelabo | Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines |
| FR2258840A1 (en) * | 1974-01-29 | 1975-08-22 | Synthelabo | (4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use |
Non-Patent Citations (1)
| Title |
|---|
| JOURNAL OF MEDICINAL CHEMISTRY, vol. 22, no. 5, 1979, pages 554-559; P.M. MANOURY et al.: "Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates" * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR0146352B1 (ko) | 1998-08-17 |
| MY104452A (en) | 1994-03-31 |
| IT8821300A0 (it) | 1988-07-08 |
| PT91079A (pt) | 1990-02-08 |
| DK336289A (da) | 1990-01-09 |
| DK336289D0 (da) | 1989-07-06 |
| FI893293A0 (fi) | 1989-07-06 |
| FI893293A7 (fi) | 1990-01-09 |
| EP0349902A2 (fr) | 1990-01-10 |
| KR900001655A (ko) | 1990-02-27 |
| IT1226386B (it) | 1991-01-15 |
| PT91079B (pt) | 1995-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
|
| PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
| AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
|
| 17P | Request for examination filed |
Effective date: 19910914 |
|
| 17Q | First examination report despatched |
Effective date: 19931110 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 19940322 |