EP0298235B1 - Zwischenwirbel-Prothese - Google Patents
Zwischenwirbel-Prothese Download PDFInfo
- Publication number
- EP0298235B1 EP0298235B1 EP88108216A EP88108216A EP0298235B1 EP 0298235 B1 EP0298235 B1 EP 0298235B1 EP 88108216 A EP88108216 A EP 88108216A EP 88108216 A EP88108216 A EP 88108216A EP 0298235 B1 EP0298235 B1 EP 0298235B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- prosthesis
- vertebrae
- intervertebral
- prosthesis body
- prosthesis according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30112—Rounded shapes, e.g. with rounded corners
- A61F2002/30133—Rounded shapes, e.g. with rounded corners kidney-shaped or bean-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30576—Special structural features of bone or joint prostheses not otherwise provided for with extending fixation tabs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30576—Special structural features of bone or joint prostheses not otherwise provided for with extending fixation tabs
- A61F2002/30578—Special structural features of bone or joint prostheses not otherwise provided for with extending fixation tabs having apertures, e.g. for receiving fixation screws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
- A61F2002/30909—Nets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0015—Kidney-shaped, e.g. bean-shaped
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S606/00—Surgery
- Y10S606/907—Composed of particular material or coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S606/00—Surgery
- Y10S606/907—Composed of particular material or coated
- Y10S606/91—Polymer
Definitions
- the invention relates to an intervertebral prosthesis for an arthrodesis.
- two adjacent vertebrae are fixed relative to one another by cross-shaped plates which are firmly connected from the dorsal side to the two vertebral bodies, for example also by screws.
- the cross plates in the dorsal region of the vertebrae which are relatively far away from the intervertebral discs - especially in the case of larger intervertebral disc damage or when a complete intervertebral disc is replaced - cause inadequate fixation at the location of the intervertebral discs, and also cause instabilities in the other Vertebrae tend to stiffen.
- an intervertebral prosthesis which consists of a disc, on the disc surfaces of which there are bead-like elevations in the form of spherical segments.
- This disc is movably supported in surgically created hollow spherical depressions in the vertebrae.
- the disc is stiff and not deformable, while the beads are elastic. Arthrodesis of two vertebrae is not possible with this construction.
- the object of the invention is to create an intervertebral prosthesis that can be implanted and fixed with relatively little operative effort, with which a fixed and stable stiffening of two vertebrae is achieved as an intervertebral disc replacement.
- This object is achieved with the present invention in that it consists of a disk-like prosthesis body which can be inserted from the ventral side between two vertebrae as an intervertebral disk replacement, and bead-like elevations are present on the disk surfaces thereof are composed of cylinder segments enclosing an acute angle.
- the new prosthesis is characterized by great simplicity, since it only consists of a plate replacing the intervertebral disc.
- the transverse stability of the arthrodesis is ensured and the primary fixation is ensured by the bulge-like elevations, which are designed as cylindrical segments enclosing an acute angle and are inserted from the ventral side into bores of the vertebral bodies that are surgically adapted to the elevations.
- the prosthesis body is kidney-shaped and / or if the thickness of the prosthesis body tapers conically from ventrally to dorsally. It is also advantageous if the angle enclosed by elevations is ⁇ / 2.
- the disk is a plastic, for example polyethylene of the specifications customary for implants, and its surfaces are covered with a metal grid, for example a multilayer wire mesh made of titanium or a titanium alloy, in order to prevent tissue from growing in and growing on and thus to promote long-term fixation.
- the disk itself is made of titanium or a titanium alloy; its disk surfaces are also provided with a structure which promotes tissue ingrowth or growth, which can also be formed, for example, by a wire mesh which is fixed to the disk with spot welds distributed over the surfaces.
- the primary fixation of the prosthesis until tissue ingrowth can be considerably improved by tabs on the convex, ventral edge of the prosthesis body provided with openings for bone screws. These tabs can both be integrated into the prosthesis body and also be present as additional individual elements; they are screwed into the vertebral bodies of the two vertebrae, whereby these can be preloaded by compressing them beforehand.
- the disk 1 forming the prosthesis body which is kidney-shaped or bean-shaped, the convex curvature being directed ventrally, has a thickness that decreases from ventrally to dorsally (FIG. 2).
- the disc 1 is for fixing in the vertebral bodies on their disc surfaces with bead-like elevations 2, which have the shape of cylinder segments.
- the two cylinder segments are perpendicular to each other, so their axes form an angle of ⁇ / 2.
- the elevations 2 extend to the dorsal edge, while in the second embodiment (FIG. 3) they are cut off in the region of the angle apex and replaced by a bridge-like web 3.
- Both disc surfaces, including the elevations 2, are covered with a multilayer titanium wire mesh 4, which is embedded in the plastic of the disc 1 in a known manner with at least one layer.
- the mesh cover serves as a structure promoting the growth and ingrowth of tissue.
- the ventral edge 5 (FIG. 1) of the prosthesis body 1 can be covered by tabs 6 for an improvement of the primary fixation - before bone tissue has grown or grown on or into the implant. While FIG. 5 shows two separate tabs 6, which only partially cover the edge 5, FIG. 6 shows a tab designed as a cross plate 7, which covers the ventral edge 5 of the prosthesis body 1 over its entire circumference.
- the tabs 6 or 7 can either be an integral part of the prosthesis body 1 or separate individual elements. They have passage openings 8 for bone screws which are screwed into the vertebrae 9.
- the openings 8 are designed as part of a spherical shell in order to facilitate alignment of the screws (not shown) in any direction.
- the tabs 6 and 7 are screwed into the vertebral bodies after they have been lightly pressed together in order to generate a contact pressure of the vertebrae 9 on the prosthesis body 1.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT88108216T ATE69943T1 (de) | 1987-07-09 | 1988-05-21 | Zwischenwirbel-prothese. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH2606/87 | 1987-07-09 | ||
CH2606/87A CH672589A5 (pt) | 1987-07-09 | 1987-07-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0298235A1 EP0298235A1 (de) | 1989-01-11 |
EP0298235B1 true EP0298235B1 (de) | 1991-12-04 |
Family
ID=4237540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP88108216A Expired - Lifetime EP0298235B1 (de) | 1987-07-09 | 1988-05-21 | Zwischenwirbel-Prothese |
Country Status (5)
Country | Link |
---|---|
US (1) | US4917704A (pt) |
EP (1) | EP0298235B1 (pt) |
AT (1) | ATE69943T1 (pt) |
CH (1) | CH672589A5 (pt) |
DE (1) | DE3866614D1 (pt) |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6802867B2 (en) | 1999-06-04 | 2004-10-12 | Depuy Acromed, Inc. | Orthopedic implant |
US7658765B2 (en) | 1999-08-18 | 2010-02-09 | Intrinsic Therapeutics, Inc. | Resilient intervertebral disc implant |
US7682396B2 (en) | 2002-11-05 | 2010-03-23 | Ldr Medical | Intervertebral disc prosthesis |
US7695516B2 (en) | 2004-12-22 | 2010-04-13 | Ldr Medical | Intervertebral disc prosthesis |
US7717961B2 (en) | 1999-08-18 | 2010-05-18 | Intrinsic Therapeutics, Inc. | Apparatus delivery in an intervertebral disc |
US7727241B2 (en) | 2003-06-20 | 2010-06-01 | Intrinsic Therapeutics, Inc. | Device for delivering an implant through an annular defect in an intervertebral disc |
US7749275B2 (en) | 1999-08-18 | 2010-07-06 | Intrinsic Therapeutics, Inc. | Method of reducing spinal implant migration |
US7842088B2 (en) | 2005-09-23 | 2010-11-30 | Ldr Medical | Intervertebral disc prosthesis |
US7867278B2 (en) | 1999-08-18 | 2011-01-11 | Intrinsic Therapeutics, Inc. | Intervertebral disc anulus implant |
US7942104B2 (en) | 2007-01-22 | 2011-05-17 | Nuvasive, Inc. | 3-dimensional embroidery structures via tension shaping |
US7946236B2 (en) | 2007-01-31 | 2011-05-24 | Nuvasive, Inc. | Using zigzags to create three-dimensional embroidered structures |
US7959679B2 (en) | 1999-08-18 | 2011-06-14 | Intrinsic Therapeutics, Inc. | Intervertebral anulus and nucleus augmentation |
US7972337B2 (en) | 2005-12-28 | 2011-07-05 | Intrinsic Therapeutics, Inc. | Devices and methods for bone anchoring |
US8002835B2 (en) | 2004-04-28 | 2011-08-23 | Ldr Medical | Intervertebral disc prosthesis |
US8323341B2 (en) | 2007-09-07 | 2012-12-04 | Intrinsic Therapeutics, Inc. | Impaction grafting for vertebral fusion |
US8439931B2 (en) | 2005-06-29 | 2013-05-14 | Ldr Medical | Instrumentation and methods for inserting an intervertebral disc prosthesis |
US8454612B2 (en) | 2007-09-07 | 2013-06-04 | Intrinsic Therapeutics, Inc. | Method for vertebral endplate reconstruction |
US8465546B2 (en) | 2007-02-16 | 2013-06-18 | Ldr Medical | Intervertebral disc prosthesis insertion assemblies |
US8858635B2 (en) | 2004-02-04 | 2014-10-14 | Ldr Medical | Intervertebral disc prosthesis |
US9265618B2 (en) | 2005-11-30 | 2016-02-23 | Ldr Medical | Intervertebral disc prosthesis and instrumentation for insertion of the prosthesis between the vertebrae |
US9333095B2 (en) | 2001-05-04 | 2016-05-10 | Ldr Medical | Intervertebral disc prosthesis, surgical methods, and fitting tools |
Families Citing this family (233)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7491205B1 (en) | 1988-06-13 | 2009-02-17 | Warsaw Orthopedic, Inc. | Instrumentation for the surgical correction of human thoracic and lumbar spinal disease from the lateral aspect of the spine |
SE462137B (sv) * | 1988-10-18 | 1990-05-14 | Freddy Rafael Astudillo Ley | Anordning foer tillslutning av en oeppning i sternum |
CA1318469C (en) * | 1989-02-15 | 1993-06-01 | Acromed Corporation | Artificial disc |
DE8912648U1 (pt) * | 1989-10-23 | 1990-11-22 | Mecron Medizinische Produkte Gmbh, 1000 Berlin, De | |
US5306307A (en) * | 1991-07-22 | 1994-04-26 | Calcitek, Inc. | Spinal disk implant |
DE4213771C1 (de) * | 1992-04-27 | 1993-09-30 | Eska Medical Gmbh & Co | Bandscheibenendoprothese |
US5306309A (en) * | 1992-05-04 | 1994-04-26 | Calcitek, Inc. | Spinal disk implant and implantation kit |
FR2694882B1 (fr) * | 1992-08-24 | 1994-10-21 | Sofamor | Prothèse discale intervertébrale. |
DE9216092U1 (pt) * | 1992-11-26 | 1993-01-14 | S + G Implants Gmbh, 2400 Luebeck, De | |
DE4323956C1 (de) * | 1993-07-19 | 1994-10-27 | Eska Medical Gmbh & Co | Wirbelkörperfusionsdübel |
US5397364A (en) * | 1993-10-12 | 1995-03-14 | Danek Medical, Inc. | Anterior interbody fusion device |
CA2551185C (en) * | 1994-03-28 | 2007-10-30 | Sdgi Holdings, Inc. | Apparatus and method for anterior spinal stabilization |
US5674296A (en) * | 1994-11-14 | 1997-10-07 | Spinal Dynamics Corporation | Human spinal disc prosthesis |
US6206922B1 (en) * | 1995-03-27 | 2001-03-27 | Sdgi Holdings, Inc. | Methods and instruments for interbody fusion |
US5782919A (en) | 1995-03-27 | 1998-07-21 | Sdgi Holdings, Inc. | Interbody fusion device and method for restoration of normal spinal anatomy |
ES2287636T3 (es) * | 1995-03-27 | 2007-12-16 | Warsaw Orthopedic, Inc. | Implante para la fusion vertebral. |
US5989289A (en) | 1995-10-16 | 1999-11-23 | Sdgi Holdings, Inc. | Bone grafts |
EP0915687A4 (en) * | 1995-12-08 | 1999-11-10 | Robert S Bray Jr | PREVIOUS STABILIZATION DEVICE |
US5865845A (en) * | 1996-03-05 | 1999-02-02 | Thalgott; John S. | Prosthetic intervertebral disc |
US5895426A (en) * | 1996-09-06 | 1999-04-20 | Osteotech, Inc. | Fusion implant device and method of use |
US20050165483A1 (en) * | 2004-01-27 | 2005-07-28 | Ray Eddie F.Iii | Bone grafts |
KR20000052740A (ko) * | 1996-10-23 | 2000-08-25 | 에스디지아이 홀딩스 인코포레이티드 | 척수간극기 |
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US6139550A (en) * | 1997-02-11 | 2000-10-31 | Michelson; Gary K. | Skeletal plating system |
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US5824094A (en) | 1997-10-17 | 1998-10-20 | Acromed Corporation | Spinal disc |
US20010016773A1 (en) * | 1998-10-15 | 2001-08-23 | Hassan Serhan | Spinal disc |
AU753521B2 (en) | 1997-10-24 | 2002-10-17 | Robert S. Bray Jr. | Bone plate and bone screw guide mechanism |
US6139579A (en) | 1997-10-31 | 2000-10-31 | Depuy Motech Acromed, Inc. | Spinal disc |
DE29901612U1 (de) * | 1998-01-23 | 1999-04-08 | Aesculap Ag & Co Kg | Zwischenwirbelimplantat |
AT405367B (de) * | 1998-01-23 | 1999-07-26 | Fuss Franz K Dipl Biomech Dr | Implantat |
US6482233B1 (en) | 1998-01-29 | 2002-11-19 | Synthes(U.S.A.) | Prosthetic interbody spacer |
US6241769B1 (en) | 1998-05-06 | 2001-06-05 | Cortek, Inc. | Implant for spinal fusion |
US6086593A (en) | 1998-06-30 | 2000-07-11 | Bonutti; Peter M. | Method and apparatus for use in operating on a bone |
EP1100416B1 (en) | 1998-07-22 | 2007-06-06 | Warsaw Orthopedic, Inc. | Threaded cylindrical multidiscoid single or multiple array disc prosthesis |
US6099531A (en) * | 1998-08-20 | 2000-08-08 | Bonutti; Peter M. | Changing relationship between bones |
US6749635B1 (en) * | 1998-09-04 | 2004-06-15 | Sdgi Holdings, Inc. | Peanut spectacle multi discoid thoraco-lumbar disc prosthesis |
JP2002524141A (ja) * | 1998-09-04 | 2002-08-06 | スパイナル ダイナミックス コーポレイション | 複数の円板を含むピーナッツ眼鏡形胸腰部椎間板プロテーゼ |
WO2000038574A1 (en) | 1998-12-23 | 2000-07-06 | Nuvasive, Inc. | Nerve surveillance cannulae systems |
US6342074B1 (en) | 1999-04-30 | 2002-01-29 | Nathan S. Simpson | Anterior lumbar interbody fusion implant and method for fusing adjacent vertebrae |
US6419704B1 (en) | 1999-10-08 | 2002-07-16 | Bret Ferree | Artificial intervertebral disc replacement methods and apparatus |
US6969404B2 (en) * | 1999-10-08 | 2005-11-29 | Ferree Bret A | Annulus fibrosis augmentation methods and apparatus |
US20060247665A1 (en) * | 1999-05-28 | 2006-11-02 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
US7273497B2 (en) * | 1999-05-28 | 2007-09-25 | Anova Corp. | Methods for treating a defect in the annulus fibrosis |
US20070038231A1 (en) * | 1999-05-28 | 2007-02-15 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
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FR2897259B1 (fr) | 2006-02-15 | 2008-05-09 | Ldr Medical Soc Par Actions Si | Cage intersomatique transforaminale a greffon de fusion intervetebrale et instrument d'implantation de la cage |
US6793677B2 (en) * | 1999-08-13 | 2004-09-21 | Bret A. Ferree | Method of providing cells and other biologic materials for transplantation |
US7435260B2 (en) * | 1999-08-13 | 2008-10-14 | Ferree Bret A | Use of morphogenetic proteins to treat human disc disease |
US6755863B2 (en) * | 1999-10-08 | 2004-06-29 | Bret A. Ferree | Rotator cuff repair using engineered tissues |
US6685695B2 (en) * | 1999-08-13 | 2004-02-03 | Bret A. Ferree | Method and apparatus for providing nutrition to intervertebral disc tissue |
US6454804B1 (en) | 1999-10-08 | 2002-09-24 | Bret A. Ferree | Engineered tissue annulus fibrosis augmentation methods and apparatus |
US7201776B2 (en) * | 1999-10-08 | 2007-04-10 | Ferree Bret A | Artificial intervertebral disc replacements with endplates |
US6425919B1 (en) | 1999-08-18 | 2002-07-30 | Intrinsic Orthopedics, Inc. | Devices and methods of vertebral disc augmentation |
EP1624832A4 (en) | 1999-08-18 | 2008-12-24 | Intrinsic Therapeutics Inc | DEVICES AND METHOD FOR AUGMENTING A WINDOW NUCLEUS |
US20040024465A1 (en) | 1999-08-18 | 2004-02-05 | Gregory Lambrecht | Devices and method for augmenting a vertebral disc |
US6936072B2 (en) * | 1999-08-18 | 2005-08-30 | Intrinsic Therapeutics, Inc. | Encapsulated intervertebral disc prosthesis and methods of manufacture |
US7060100B2 (en) * | 1999-10-08 | 2006-06-13 | Ferree Bret A | Artificial disc and joint replacements with modular cushioning components |
US6648920B2 (en) * | 1999-10-08 | 2003-11-18 | Bret A. Ferree | Natural and synthetic supplements to engineered annulus and disc tissues |
US20040172019A1 (en) * | 1999-10-08 | 2004-09-02 | Ferree Bret A. | Reinforcers for artificial disc replacement methods and apparatus |
US20030026788A1 (en) * | 1999-10-08 | 2003-02-06 | Ferree Bret A. | Use of extracellular matrix tissue to preserve cultured cell phenotype |
US20030004574A1 (en) * | 1999-10-08 | 2003-01-02 | Ferree Bret A. | Disc and annulus augmentation using biologic tissue |
US6645247B2 (en) * | 1999-10-08 | 2003-11-11 | Bret A. Ferree | Supplementing engineered annulus tissues with autograft of allograft tendons |
US20040186573A1 (en) * | 1999-10-08 | 2004-09-23 | Ferree Bret A. | Annulus fibrosis augmentation methods and apparatus |
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- 1988-05-21 EP EP88108216A patent/EP0298235B1/de not_active Expired - Lifetime
- 1988-06-08 US US07/204,020 patent/US4917704A/en not_active Expired - Lifetime
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Also Published As
Publication number | Publication date |
---|---|
CH672589A5 (pt) | 1989-12-15 |
ATE69943T1 (de) | 1991-12-15 |
US4917704A (en) | 1990-04-17 |
EP0298235A1 (de) | 1989-01-11 |
DE3866614D1 (de) | 1992-01-16 |
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