EP0259485A4 - Schwermetallsalze von hyaluronsäure zur verwendung als antimikrobielles mittel. - Google Patents

Schwermetallsalze von hyaluronsäure zur verwendung als antimikrobielles mittel.

Info

Publication number
EP0259485A4
EP0259485A4 EP19870902255 EP87902255A EP0259485A4 EP 0259485 A4 EP0259485 A4 EP 0259485A4 EP 19870902255 EP19870902255 EP 19870902255 EP 87902255 A EP87902255 A EP 87902255A EP 0259485 A4 EP0259485 A4 EP 0259485A4
Authority
EP
European Patent Office
Prior art keywords
metal salts
heavy metal
hyaluronic acid
antimicrobial agents
acid useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19870902255
Other languages
English (en)
French (fr)
Other versions
EP0259485A1 (de
Inventor
Abraham Nimrod
Benjamin Greenman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Savient Pharmaceuticals Inc
Original Assignee
Savient Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/840,419 external-priority patent/US4746504A/en
Priority claimed from US07/023,666 external-priority patent/US4784991A/en
Application filed by Savient Pharmaceuticals Inc filed Critical Savient Pharmaceuticals Inc
Publication of EP0259485A1 publication Critical patent/EP0259485A1/de
Publication of EP0259485A4 publication Critical patent/EP0259485A4/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dentistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19870902255 1986-03-14 1987-03-13 Schwermetallsalze von hyaluronsäure zur verwendung als antimikrobielles mittel. Ceased EP0259485A4 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US06/840,419 US4746504A (en) 1986-03-14 1986-03-14 Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
US840419 1986-03-14
US1947487A 1987-02-26 1987-02-26
US07/023,666 US4784991A (en) 1986-03-14 1987-03-09 Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
US23666 1987-03-09
US19474 1987-03-09

Publications (2)

Publication Number Publication Date
EP0259485A1 EP0259485A1 (de) 1988-03-16
EP0259485A4 true EP0259485A4 (de) 1988-07-29

Family

ID=27361231

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19870902255 Ceased EP0259485A4 (de) 1986-03-14 1987-03-13 Schwermetallsalze von hyaluronsäure zur verwendung als antimikrobielles mittel.

Country Status (4)

Country Link
EP (1) EP0259485A4 (de)
AU (1) AU600483B2 (de)
CA (1) CA1291123C (de)
WO (1) WO1987005517A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0356435B1 (de) * 1987-03-19 1995-10-18 Arthropharm Pty. Limited Antientzündungsmittel und zusammensetzungen
HU203372B (en) * 1989-02-24 1991-07-29 Richter Gedeon Vegyeszet Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient
DE4115454A1 (de) * 1991-05-11 1992-11-12 Basf Ag Eisen-(iii)-hyaluronate
JP3419785B2 (ja) * 1995-09-28 2003-06-23 サングスタット メディカル コーポレイション 免疫抑制剤としてのヒアルロン酸の使用
HU225991B1 (en) * 1997-04-29 2008-02-28 Richter Gedeon Nyrt Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer
HU225329B1 (en) * 1996-09-12 2006-09-28 Richter Gedeon Vegyeszet Use of zinc or cobalt hyaluronate associate for the manufacture of pharmaceutical compositions of antimicrobial activity
JP2003089647A (ja) * 1999-03-10 2003-03-28 Takada Seiyaku Kk 関節性疾患治療剤
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
AU8136801A (en) * 2000-07-31 2002-02-13 Dermal Res Lab Inc Methods of preventing or treating diseases and conditions using complex carbohydrates
GB2392913B (en) * 2002-09-11 2007-04-04 Johnson & Johnson Medical Ltd Wound dressings comprising complexes of oxidised celluloses with silver
PL207044B1 (pl) 2002-09-11 2010-10-29 Johnson & Johnson Medical Ltd Materiał opatrunkowy na rany zawierający kompleks utlenionej celulozy ze srebrem, opatrunek zawierający ten materiał, oraz zastosowanie kompleksu do wytwarzania materiału opatrunkowego
GB2402880B (en) * 2003-06-20 2008-01-23 Johnson & Johnson Medical Ltd Antimicrobial compositions comprising silver
GB2408206B (en) 2003-11-18 2007-11-28 Johnson & Johnson Medical Ltd Antioxidant and antimicrobial wound dressing materials
AU2004248971A1 (en) * 2003-06-20 2004-12-29 Johnson & Johnson Medical Limited Antioxidant wound dressing materials
US8425926B2 (en) 2003-07-16 2013-04-23 Yongxing Qiu Antimicrobial medical devices
US20110130473A1 (en) 2007-11-13 2011-06-02 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
TWI516269B (zh) 2009-08-14 2016-01-11 禾伸堂生技股份有限公司 使用於炎症性腸疾病（ｉｂｄ）治療和預防之透明質酸混合物
TWI383796B (zh) 2009-08-14 2013-02-01 Holy Stone Healthcare Co Ltd Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer
US8575130B2 (en) 2010-01-04 2013-11-05 Holy Stone Healthcare Co., Ltd. Mixture of hyaluronic acid for treating and preventing inflammatory bowel disease
US8722644B2 (en) 2010-01-04 2014-05-13 Holy Stone Healthcare Co., Ltd. Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer
US9029347B2 (en) 2010-08-05 2015-05-12 Holy Stone Healthcare Co., Ltd. Method and mixture for treating and preventing inflammatory bowel disease
IT1402786B1 (it) * 2010-11-19 2013-09-18 Fidia Farmaceutici Composizioni farmaceutiche ad attivita' antibatterica e cicatrizzante
CN102552309B (zh) * 2010-12-15 2013-06-05 北京理工大学 一种透明质酸金的用途及其制备方法
DK2543357T3 (en) 2011-07-07 2018-07-02 Holy Stone Healthcare Co Ltd COMPOSITION FOR USE FOR TREATMENT AND PREVENTION OF INFLAMMATION-RELATED DISORDERS
ES2665254T3 (es) 2011-07-12 2018-04-25 Holy Stone Healthcare Co., Ltd. Composiciones que comprenden ácido hialurónico para tratamiento y prevención de enfermedades relacionadas con las mucosas
FR2978664B1 (fr) 2011-08-04 2014-01-10 Petcare Innovation Composition antiseptique
CZ303722B6 (cs) * 2012-01-16 2013-04-03 Contipro Biotech S.R.O. Kyselina hyaluronová znacená tritiem, zpusob znacení kyseliny hyaluronové tritiem a její pouzití
RU2014137454A (ru) * 2012-02-17 2016-04-10 Кимфлексор, С.Л. Серебряные и золотые соли частично деполимеризованного гликозаминогликана
FR3002452B1 (fr) 2013-02-28 2016-02-12 Dermaconcept Jmc Composition dermatologique antimicrobienne topique
CN112500505A (zh) * 2020-11-19 2021-03-16 徐州医科大学 一种高分子银复合物及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197718A2 (de) * 1985-04-05 1986-10-15 FIDIA S.p.A. Arzneimittel zur topischen Anwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172128A (en) * 1975-03-26 1979-10-23 Erhard Thiele Process of degrading and regenerating bone and tooth material and products
US4211769A (en) * 1977-08-24 1980-07-08 Takeda Chemical Industries, Ltd. Preparations for vaginal administration
US4487865A (en) * 1983-12-15 1984-12-11 Biomatrix, Inc. Polymeric articles modified with hyaluronate
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197718A2 (de) * 1985-04-05 1986-10-15 FIDIA S.p.A. Arzneimittel zur topischen Anwendung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8705517A1 *

Also Published As

Publication number Publication date
AU7206887A (en) 1987-10-09
EP0259485A1 (de) 1988-03-16
WO1987005517A1 (en) 1987-09-24
AU600483B2 (en) 1990-08-16
CA1291123C (en) 1991-10-22

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19880314

A4 Supplementary search report drawn up and despatched

Effective date: 19880729

17Q First examination report despatched

Effective date: 19900112

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19910528

RIN1 Information on inventor provided before grant (corrected)

Inventor name: NIMROD, ABRAHAM

Inventor name: GREENMAN, BENJAMIN