EP0175701A1 - Skin treatment compositions - Google Patents

Skin treatment compositions

Info

Publication number
EP0175701A1
EP0175701A1 EP19850900954 EP85900954A EP0175701A1 EP 0175701 A1 EP0175701 A1 EP 0175701A1 EP 19850900954 EP19850900954 EP 19850900954 EP 85900954 A EP85900954 A EP 85900954A EP 0175701 A1 EP0175701 A1 EP 0175701A1
Authority
EP
European Patent Office
Prior art keywords
weight
active ingredients
composition according
acceptable carrier
cosmetically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19850900954
Other languages
German (de)
French (fr)
Inventor
John Francis Plunkett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0175701A1 publication Critical patent/EP0175701A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

Definitions

  • the invention relates to skin treatment compositions and in particular to compositions which lessen brown pigmentation marks on the hands, face, arms and body.
  • a flawless skin is a woman's chief beauty and is a characteristic of normal skin.
  • the invention provides a composition for topical application comprising, in low concentration, active ingredients hydroquinone or its monobenzyl ether, and salicyclic acid together with a cosmetically acceptable carrier.
  • a process for preparing a topical application which comprises mixing together the ingredients in the cosmetically acceptable carrier and then gradually adding thereto the active ingredients and mixing until dispersed.
  • composition according to the invention can contain ingredients other than those below mentioned, depending upon the form of the intended product. It is, for example possible, to include moisturisers, sunscreen agents, preservatives, anti-oxidants, emulsifiers, perfumes and colouring agents. Such other ingredients are well known in the trade and, as they do not form part of the present invention, will not be further discussed.
  • Example 1 The invention is illustrated by the following examples of a composition for topical application to human skin.
  • Example 1 The invention is illustrated by the following examples of a composition for topical application to human skin.
  • This example illustrates the preferred composition prepared from the following ingredients:
  • This example illustrates the another composition prepared from the following ingredients:
  • Vitamin E oil - 2,000 I.U./100G
  • composition of the cosmetically acceptable carrier may be varied without departing from the scope of the present invention as defined by the following claims.

Abstract

Compositions de traitement cutané qui réduisent les marques de pigmentation brunes sur le corps, contenant à de faibles concentrations (0,5 à 2,0% en poids) en tant qu'ingrédients actifs de l'hydroquinone ou son éther monobenzylique et de l'acide salicylique avec un porteur cosmétiquement acceptable.Skin treatment compositions which reduce brown pigmentation marks on the body, containing in low concentrations (0.5 to 2.0% by weight) as active ingredients of hydroquinone or its monobenzyl ether and salicylic acid with a cosmetically acceptable carrier.

Description

SKIN TREATMENT COMPOSITIONS
The invention relates to skin treatment compositions and in particular to compositions which lessen brown pigmentation marks on the hands, face, arms and body. A flawless skin is a woman's chief beauty and is a characteristic of normal skin.
With age and exposure to ultra-violet radiation* excess pigmentation in the skin gives rise to areas of brown or darkened marks. These commonly occur on the hands, arms, neck and face.
Whilst cosmetics can mask the brown spots they in no way act to alleviate the condition.
It is apparent that there exists a need for an effective treatment for such skin blemishes which will restore the condition of the skin to normal.
It was discovered that a combination, in low concentration 0.5% - 2.0% weight/weight, of hydroquinone or its monobenzyl ether, and salicyclic acid as active ingredients in a cosmetically acceptable carrier acted synergistically.
Accordingly, the invention provides a composition for topical application comprising, in low concentration, active ingredients hydroquinone or its monobenzyl ether, and salicyclic acid together with a cosmetically acceptable carrier.
In a further aspect of the invention there is provided a process for preparing a topical application, which comprises mixing together the ingredients in the cosmetically acceptable carrier and then gradually adding thereto the active ingredients and mixing until dispersed.
The composition according to the invention can contain ingredients other than those below mentioned, depending upon the form of the intended product. It is, for example possible, to include moisturisers, sunscreen agents, preservatives, anti-oxidants, emulsifiers, perfumes and colouring agents. Such other ingredients are well known in the trade and, as they do not form part of the present invention, will not be further discussed.
The invention is illustrated by the following examples of a composition for topical application to human skin. Example 1
This example illustrates the preferred composition prepared from the following ingredients:
Active Ingredient %weight/weight monobenzyl ether 1.5 salicyclic acid 1.5
Cosmetically Acceptable Carrier %weight/weight
Vitamin E oil - 2,000 I, .U./100G
Panthenol 0.5
Escalol 3
Cetomacrogol Wax 3.2
Cetostearyl Alcohol 9.7
Soft White Paraffin 8.6
Liquid Paraffin 6.7
Chlorocresol 0.1
Arlacel 165 2.5
Propylene Glycol 4.55
Glyce ine 9
Water 47.15 The vitamin E oil, cetomacrogol 1,000 wax, cetostearyl alcohol, soft white paraffin, liquid paraffin, chlorocresol escalol 507 and arlacel 165 were mixed together at a f temperature between 70 - 80°C. - Mixture (1) .
5 In a second container propylene glycol, glycerine,
D-panthenol and water were mixed together at a temperature between 70 - 80°C. - Mixture (2).
Add (2) to (1) while mixing with silverson.
Continue mixing and gradually add the active
10 ingredients, salicylic acid and mono-benzone. Continue mixing until completely dispersed.
Cool the final mixture and re-mix the following day.
Tests have been carried out in vivo and have proved most encouraging.
15 Example 2
This example illustrates the another composition prepared from the following ingredients:
Active Ingredient %weight/weight hydroquinone 1.0
20 salicyclic acid 1.5
Cosmetically Acceptable Carrier %weight/weight
Vitamin E oil - 2,000 I.U./100G
Panthenol 0.5
Escalol 3 25 Cetomacrogol Wax 3.2
Cetostearyl Alcohol 9.7
* Soft White Paraffin 8.6
Liquid Paraffin 6.7
Chlorocresol 0.1
30 Arlacel 165 2.5
Propylene Glycol 4.55
Glycerine 9
Water remainder This composition was prepared in a similar manner as set out in Example 1.
It will be apparent to those skilled in the art that the composition of the cosmetically acceptable carrier may be varied without departing from the scope of the present invention as defined by the following claims.

Claims

Claims :
1. A composition for topical application comprising, in low concentration, active ingredients hydroquinone or its monobenzyl ether, and salicyclic acid together with a cosmetically acceptable carrier.
2. A composition according to claim 1, in which each of the active ingredients are present in a concentration of 0.5% - 2.0% weight/weight.
3. A composition according to claim 1, as herein described in Example 1 or 2.
4. A method of preparing a composition according to any of the preceding claims, which comprises mixing together the ingredients in the cosmetically acceptable carrier and then gradually adding thereto the active ingredients and mixing until dispersed.
5. - A method of preparing a composition according to claim 4, wherein each of the active ingredients are present in a concentraton of 0.5 - 2.0% weight/weight.
6. A method of preparing a composition according to claim 1, as herein described in Example 1.
EP19850900954 1984-03-19 1985-02-19 Skin treatment compositions Withdrawn EP0175701A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU4128/84 1984-03-19
AU412884 1984-03-19

Publications (1)

Publication Number Publication Date
EP0175701A1 true EP0175701A1 (en) 1986-04-02

Family

ID=3694594

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850900954 Withdrawn EP0175701A1 (en) 1984-03-19 1985-02-19 Skin treatment compositions

Country Status (2)

Country Link
EP (1) EP0175701A1 (en)
WO (1) WO1985004101A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792443A (en) * 1985-12-20 1988-12-20 Warner-Lambert Company Skin bleaching preparations
US5279834A (en) * 1987-06-12 1994-01-18 Lvmh Recherche Pharmaceutical or cosmetic composition containing hydroquinone and kojic acid
FR2616325B1 (en) * 1987-06-12 1990-11-09 Moet Hennessy Rech COMPOSITION CONTAINING HYDROQUINONE AND KOJIC ACID AND PHARMACEUTICAL COMPOSITION, ESPECIALLY DERMATOLOGICAL, WITH DEPIGMENTING OR ANTI-INFLAMMATORY ACTIVITY, OR COSMETIC COMPRISING KOJIC ACID AND HYDROQUINONE
US5523077A (en) * 1992-02-06 1996-06-04 Yale University Composition and method for whitening skin
WO1993021899A1 (en) * 1992-05-05 1993-11-11 The Procter & Gamble Company Acne treating composition
ATE171616T1 (en) * 1992-05-15 1998-10-15 Shiseido Co Ltd EXTERNAL SKIN PREPARATION
DE4420625C1 (en) * 1994-06-14 1995-11-02 Beiersdorf Ag Active substance combination with a content of glycerylalkyl ethers and cosmetic and dermatological preparations containing such active substance combinations
FR2754253A1 (en) * 1996-10-07 1998-04-10 Roche Posay Lab Pharma Composition containing hydroquinone and salicylic acid compound
US20030017181A1 (en) 2001-05-31 2003-01-23 Rood Gloria A. Dermatological compositions and methods
DE102006053360A1 (en) * 2006-11-10 2008-05-15 Evonik Stockhausen Gmbh Skin cleansing preparations, in particular cold protection cream

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1224145A (en) * 1969-01-16 1971-03-03 Dso Farmacim Composition for bleaching hyperpigmentation of the skin
US3856934A (en) * 1970-06-24 1974-12-24 A Kligman Skin depigmentation
US3821370A (en) * 1971-03-11 1974-06-28 L Tenta Topical composition for treating seborrheic keratosis
US3949072A (en) * 1971-03-11 1976-04-06 Tenta Louis T Topical composition for treatment of seborrheic keratosis
US4136166A (en) * 1977-04-18 1979-01-23 Helena Rubinstein, Inc. Skin lightening composition
DE3127590A1 (en) * 1980-07-12 1982-08-12 Kozak, Pavel, 6600 Saarbrücken Composition for the external treatment of skin disorders

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO8504101A1 *

Also Published As

Publication number Publication date
WO1985004101A1 (en) 1985-09-26

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