EP0034595A1 - Nouvelles compositions pour la revelation et l'inhibition de la plaque dentaire - Google Patents

Nouvelles compositions pour la revelation et l'inhibition de la plaque dentaire

Info

Publication number
EP0034595A1
EP0034595A1 EP80901502A EP80901502A EP0034595A1 EP 0034595 A1 EP0034595 A1 EP 0034595A1 EP 80901502 A EP80901502 A EP 80901502A EP 80901502 A EP80901502 A EP 80901502A EP 0034595 A1 EP0034595 A1 EP 0034595A1
Authority
EP
European Patent Office
Prior art keywords
dental plaque
compositions according
constituents
compositions
revealing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP80901502A
Other languages
German (de)
English (en)
French (fr)
Inventor
Jean-Noel Thorel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP0034595A1 publication Critical patent/EP0034595A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/411—Aromatic amines, i.e. where the amino group is directly linked to the aromatic nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42—Colour properties
    • A61K2800/43—Pigments; Dyes

Definitions

  • the present invention relates to new compositions for dental hygiene and treatment having, among other aims, that of revealing and treating dental plaque.
  • a dental plaque denotes a film depositing on the surface of the teeth and which is interposed between the teeth and the oral environment. It is essentially made up of a layer of more or less denatured natural and salivary proteins, salivary mucin and various living or dead microorganisms. Physico-chemically, dental plaque has properties linked to its high protein content. This largely protein film therefore constitutes a barrier between the teeth and the buccal volume in which the free saliva is slightly acidic or substantially neutral (pH 5.6 to 7.6 most generally). It tends to be more acidic at rest than during the active period.
  • the object of the present invention is therefore, when the user so desires, and in particular when he is washing his teeth, to allow him to see appear, thanks to a clear coloration, said dental plaque, coloration then easily eliminated by washing and / or conventional brushing generally carried out using toothpaste.
  • compositions revealing dental plaque in accordance with the invention, only, which requires subsequent elimination, or to use a unique composition including that according to the invention revealing dental plaque by coloring and the constituents of any conventional ifrice tooth.
  • the latter solution being the simplest, we will insist on it in the examples which follow, without this limiting the scope of the invention.
  • compositions according to the present invention therefore contain at least one body hereinafter called a developer which brings to the dental plaque a color which does not appear or appears differently on the other surfaces of the oral cavity.
  • a developer which brings to the dental plaque a color which does not appear or appears differently on the other surfaces of the oral cavity.
  • This staining of dental plaque can be obtained using any product which, in sufficient concentration, fixes physically, chemically and / or biologically, a layer, a film or particles, the time necessary for observation, and can then be easily removed. It is therefore important that the coloration be apparent during this observation, so that it can appear only at the time of contact between developer and dental plaque, by physical, chemical and / or biological interaction between the developers and one or more constituents of dental plaque.
  • compositions having the following properties:
  • a toothpaste is prepared on the basis of the following weight composition given as a percentage, with mention of the property generally considered to be the most characteristic. teristic in the context of the present invention:
  • Nipasol propyl parahydroxybenzoate 0.07 preservative
  • solution B 100 liters of purified water are dissolved and with electric stirring, the sodium rinocleatate, sodium saccharinate and sodium dihydroxyallantoinate, which gives the so-called solution B.
  • a sufficient quantity of purified water is introduced into a disperser with the mixture of silica, xylitol, oxy- of titanium and aluminum hydroxide. The mixture is allowed to homogenize. Solution B is then added by filtering and pumping, then boric acid, lauric alcohol sul fane and any chloroform. After a few minutes, solution A is added as well as the fragrance essences in which the preservatives have previously been dissolved. The apparatus is left to rotate until good homogeneity, then the neutral red is incorporated and it is turned until perfect homogeneity, that is to say for about thirty minutes. Then deaerated under vacuum for a quarter of an hour.
  • the paste thus obtained is crushed and stored in tanks for 48 hours.
  • composition in accordance with the invention can be used as a toothpaste, the dental plaque being, in a first phase, directly colored, here essentially thanks to neutral red, the toothpaste acting in a second phase, removing the staining with all or part of the dental plaque.
  • neutral red indicates the pH (red at pH 6.8, yellow at 8.0) and allows the revelation and detection of plaque microorganisms.
  • cetylpyridinium chloride associated with neutral red acts as an energetic inhibitor of plaque and dissolves mucins.
  • Example 1 is repeated, replacing cetylpyridinium chloride with chlorhexidine and neutral red (Basic Red 5 of the Color Index) with toluidine blue 0 (Basic blue 17 of the Color Index) or methyl violet (Basic Violet of color Index).
  • Example 3 We obtain results as satisfactory as in Example 1 and in the case of methyl violet (Example 3) an enhanced action on the microorganisms of the plate.
  • Example 3 there are obtained revealing, inhibiting, toothpaste and, with certain dyes, indicating pH compositions.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
EP80901502A 1979-08-20 1981-03-09 Nouvelles compositions pour la revelation et l'inhibition de la plaque dentaire Withdrawn EP0034595A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7920929A FR2463613A1 (fr) 1979-08-20 1979-08-20 Nouvelles compositions pour la revelation de la plaque dentaire
FR7920929 1979-08-20

Publications (1)

Publication Number Publication Date
EP0034595A1 true EP0034595A1 (fr) 1981-09-02

Family

ID=9228939

Family Applications (1)

Application Number Title Priority Date Filing Date
EP80901502A Withdrawn EP0034595A1 (fr) 1979-08-20 1981-03-09 Nouvelles compositions pour la revelation et l'inhibition de la plaque dentaire

Country Status (10)

Country Link
EP (1) EP0034595A1 (el)
JP (1) JPS57501280A (el)
AU (1) AU6223080A (el)
BE (1) BE884850A (el)
FR (1) FR2463613A1 (el)
GR (1) GR82353B (el)
NO (1) NO811325L (el)
OA (1) OA07365A (el)
PT (1) PT71709B (el)
WO (1) WO1981000513A1 (el)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009017090A1 (de) * 2009-04-15 2010-11-11 Festo Ag & Co. Kg Verfahren zur Ermittlung von Reglerparametern einer Regelungseinrichtung zur Antriebsregelung eines Antriebssystems

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01246214A (ja) * 1988-03-28 1989-10-02 Shiseido Co Ltd 口腔用組成物
FR2791890B1 (fr) * 1999-04-12 2004-12-10 Gilbert Lab Solution de chlorhexidine alcoolique coloree et sa methode de fabrication
ITMI20011315A1 (it) * 2001-06-21 2002-12-21 Herbariorum Medicaminum Offici Composizione per pasta dentifricia antiplacca con rilevatore di placca
US20050058602A1 (en) * 2003-09-11 2005-03-17 The Procter & Gamble Company Dye composition and method for detection of demineralized lesions in teeth
PL1951184T3 (pl) 2005-11-09 2012-06-29 Valeant Pharmaceuticals Int Inc Kompozycje do wybielania zębów i sposoby
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
CA2742942C (en) 2008-11-07 2016-09-06 Klox Technologies Inc. Combination of an oxidant and a photoactivator for the healing of wounds
CA2948258C (en) 2009-07-17 2021-06-01 Klox Technologies Inc. Oral composition for accelerating closure of an open dental socket
AU2011381025B2 (en) * 2011-11-15 2015-09-17 Colgate-Palmolive Company Oral care gel dispenser systems
IN2014DN03045A (el) 2011-11-15 2015-05-08 Colgate Palmolive Co
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
KR20150082189A (ko) 2012-09-14 2015-07-15 밸리언트 파마슈티컬즈 인터내셔널, 인코퍼레이션 치아미백용 조성물 및 치아미백 방법
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
MX366292B (es) 2013-07-03 2019-07-04 Klox Tech Inc Composiciones biofotónicas que comprenden un cromóforo y un agente gelificante para el tratamiento de heridas.
CN106413766A (zh) 2014-04-01 2017-02-15 克洛克斯科技公司 组织填料组合物及使用方法
RU2017117187A (ru) 2014-10-31 2018-11-30 Клокс Текнолоджиз Инк. Фотоактивируемые волокна и тканые материалы

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723613A (en) * 1971-01-22 1973-03-27 J Derdivanis Dental plaque disclosing agent
AU6703974A (en) * 1973-03-30 1975-09-25 Selwyn S L Dental plaque disclosing agents
US4080441A (en) * 1976-12-27 1978-03-21 Colgate-Palmolive Company Antibacterial oral composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO8100513A1 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009017090A1 (de) * 2009-04-15 2010-11-11 Festo Ag & Co. Kg Verfahren zur Ermittlung von Reglerparametern einer Regelungseinrichtung zur Antriebsregelung eines Antriebssystems

Also Published As

Publication number Publication date
PT71709A (fr) 1980-09-01
PT71709B (fr) 1981-06-17
OA07365A (fr) 1984-06-30
NO811325L (no) 1981-04-15
FR2463613A1 (fr) 1981-02-27
WO1981000513A1 (fr) 1981-03-05
GR82353B (el) 1984-12-13
FR2463613B1 (el) 1983-01-28
JPS57501280A (el) 1982-07-22
AU6223080A (en) 1981-03-18
BE884850A (fr) 1980-12-16

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19810907

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Effective date: 19840124